GREMLIN Database
YJJP - Inner membrane protein YjjP
UniProt: P0ADD5 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12592
Length: 256 (240)
Sequences: 2333 (1672)
Seq/√Len: 108.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
91_L105_R5.7101.00
124_G149_T4.5101.00
105_R108_Q4.3371.00
98_D101_G4.2711.00
124_G145_F3.8631.00
88_I109_I3.8361.00
8_A100_K3.5681.00
115_P118_L3.4791.00
41_L92_A3.3531.00
226_L230_A3.1991.00
127_C148_S3.1971.00
128_A145_F2.7301.00
154_I175_A2.5341.00
8_A103_E2.4911.00
213_A229_W2.4581.00
20_L25_A2.4341.00
131_C136_G2.4271.00
92_A102_V2.4251.00
137_G140_G2.4211.00
16_C85_V2.3031.00
217_M225_G2.2291.00
18_L70_R2.1781.00
174_F246_A2.1401.00
17_G34_S2.0881.00
33_L89_V2.0791.00
91_L96_L2.0351.00
87_H91_L2.0211.00
34_S48_S1.9771.00
143_I183_L1.9371.00
147_A179_I1.9011.00
85_V106_F1.8941.00
128_A141_A1.8841.00
18_L22_Q1.8601.00
17_G55_I1.8371.00
104_K108_Q1.8351.00
88_I102_V1.8311.00
15_Q107_S1.8281.00
16_C37_L1.8181.00
123_V152_M1.8021.00
13_C38_G1.7261.00
16_C106_F1.6541.00
86_Q90_I1.6541.00
56_V69_T1.6521.00
130_F202_L1.6521.00
13_C37_L1.6391.00
116_R156_Q1.6361.00
182_L186_L1.5941.00
38_G46_V1.5821.00
202_L205_V1.5801.00
131_C199_A1.5771.00
19_F85_V1.5511.00
80_H84_E1.5481.00
15_Q103_E1.5331.00
86_Q89_V1.4991.00
151_A176_A1.4981.00
181_G246_A1.4971.00
12_L102_V1.4691.00
166_Q238_A1.4671.00
153_Y157_L1.4611.00
140_G192_T1.4541.00
120_A149_T1.4411.00
188_T191_N1.4241.00
13_C34_S1.3841.00
101_G104_K1.3821.00
142_V146_F1.3391.00
12_L16_C1.3340.99
213_A232_A1.3190.99
121_L145_F1.3050.99
178_T182_L1.3020.99
43_M59_T1.2910.99
31_D71_K1.2810.99
9_V41_L1.2800.99
177_T246_A1.2670.99
26_E31_D1.2520.99
75_R231_I1.2500.99
177_T243_V1.2470.99
16_C89_V1.2420.99
151_A203_L1.2410.99
139_D142_V1.2340.99
25_A30_V1.2180.99
58_T67_T1.1910.99
100_K105_R1.1790.99
195_I199_A1.1760.99
164_H169_F1.1760.99
33_L36_R1.1620.99
53_N227_A1.1430.98
14_I68_S1.1410.98
123_V148_S1.1360.98
157_L160_Q1.1220.98
103_E107_S1.1180.98
16_C33_L1.1100.98
97_L102_V1.0980.98
213_A218_F1.0900.98
26_E215_A1.0840.98
221_H224_T1.0670.98
15_Q19_F1.0640.97
169_F235_L1.0640.97
54_A69_T1.0620.97
154_I171_L1.0460.97
35_S39_R1.0440.97
51_S58_T1.0380.97
21_L30_V1.0320.97
33_L86_Q1.0300.97
16_C19_F1.0300.97
52_S222_I1.0170.97
29_L140_G1.0170.97
37_L41_L1.0150.97
191_N196_A1.0130.97
210_L236_T1.0110.97
49_S54_A1.0060.96
41_L88_I0.9920.96
40_A93_E0.9690.96
179_I183_L0.9650.96
81_V109_I0.9640.96
29_L89_V0.9620.95
140_G190_S0.9530.95
37_L92_A0.9490.95
36_R93_E0.9470.95
117_W121_L0.9470.95
173_A176_A0.9420.95
118_L122_M0.9400.95
184_L188_T0.9360.95
101_G105_R0.9330.95
205_V243_V0.9330.95
206_P236_T0.9270.94
114_Y118_L0.9250.94
32_E36_R0.9200.94
84_E110_Q0.9100.94
131_C144_T0.9040.94
140_G196_A0.8990.93
183_L189_F0.8980.93
36_R89_V0.8980.93
148_S152_M0.8850.93
46_V57_L0.8780.93
48_S57_L0.8770.93
127_C203_L0.8770.93
242_G246_A0.8760.93
142_V145_F0.8750.93
127_C202_L0.8720.92
12_L99_Y0.8640.92
126_S130_F0.8450.91
9_V13_C0.8390.91
211_I224_T0.8370.91
42_G129_C0.8330.91
83_T87_H0.8290.90
19_F106_F0.8280.90
95_H102_V0.8270.90
58_T78_N0.8260.90
105_R109_I0.8190.90
84_E88_I0.7890.88
91_L97_L0.7840.88
107_S110_Q0.7810.88
211_I221_H0.7730.87
178_T246_A0.7730.87
9_V43_M0.7710.87
23_H81_V0.7710.87
174_F249_I0.7680.87
39_R178_T0.7670.87
33_L90_I0.7660.87
117_W153_Y0.7640.86
78_N81_V0.7630.86
52_S218_F0.7590.86
157_L161_R0.7560.86
116_R157_L0.7560.86
37_L89_V0.7540.86
217_M231_I0.7540.86
210_L229_W0.7530.86
134_N212_N0.7510.85
75_R220_G0.7510.85
29_L240_C0.7500.85
233_S237_L0.7490.85
201_V239_T0.7490.85
176_A203_L0.7390.85
33_L82_V0.7370.84
215_A231_I0.7360.84
31_D52_S0.7360.84
12_L19_F0.7330.84
19_F23_H0.7310.84
121_L125_L0.7310.84
124_G128_A0.7310.84
145_F149_T0.7210.83
111_P114_Y0.7210.83
47_E70_R0.7190.83
19_F81_V0.7170.83
236_T240_C0.7160.83
136_G216_D0.7160.83
120_A153_Y0.7100.82
27_S52_S0.7080.82
128_A199_A0.7040.82
107_S146_F0.7030.82
31_D79_M0.7020.81
100_K104_K0.7010.81
15_Q70_R0.7010.81
174_F245_M0.7000.81
91_L95_H0.6970.81
26_E86_Q0.6970.81
55_I84_E0.6930.81
32_E90_I0.6920.81
146_F150_T0.6920.81
97_L101_G0.6880.80
200_S248_T0.6830.80
60_I64_Q0.6820.80
99_Y102_V0.6810.79
147_A151_A0.6810.79
118_L121_L0.6800.79
126_S203_L0.6790.79
218_F229_W0.6780.79
23_H109_I0.6750.79
31_D221_H0.6720.79
127_C155_R0.6700.78
113_R119_V0.6670.78
34_S57_L0.6630.78
62_D100_K0.6630.78
48_S51_S0.6600.77
197_M243_V0.6590.77
11_R60_I0.6560.77
105_R182_L0.6550.77
32_E131_C0.6520.76
151_A172_T0.6510.76
134_N205_V0.6510.76
28_A31_D0.6490.76
22_Q74_D0.6490.76
23_H82_V0.6480.76
123_V151_A0.6480.76
147_A196_A0.6480.76
57_L130_F0.6440.76
9_V92_A0.6420.75
176_A243_V0.6390.75
120_A156_Q0.6380.75
32_E199_A0.6350.75
170_C238_A0.6350.75
115_P121_L0.6330.74
203_L208_F0.6320.74
183_L186_L0.6320.74
20_L30_V0.6310.74
206_P212_N0.6300.74
218_F225_G0.6270.74
70_R213_A0.6270.74
41_L93_E0.6260.74
84_E87_H0.6250.73
25_A86_Q0.6220.73
216_D220_G0.6210.73
120_A152_M0.6210.73
220_G231_I0.6200.73
128_A246_A0.6200.73
205_V232_A0.6200.73
174_F181_G0.6200.73
69_T79_M0.6200.73
115_P160_Q0.6180.73
28_A222_I0.6180.73
184_L190_S0.6170.72
36_R90_I0.6160.72
116_R119_V0.6150.72
110_Q249_I0.6150.72
52_S224_T0.6150.72
94_H104_K0.6140.72
137_G191_N0.6120.72
80_H114_Y0.6110.72
105_R192_T0.6110.72
62_D98_D0.6070.71
169_F217_M0.6030.71
76_G171_L0.6030.71
67_T84_E0.6020.71
67_T106_F0.6020.71
75_R216_D0.6010.70
148_S211_I0.6000.70
87_H109_I0.6000.70
24_G224_T0.5990.70
11_R103_E0.5980.70
24_G82_V0.5980.70
134_N245_M0.5960.70
41_L98_D0.5960.70
121_L146_F0.5920.69
220_G247_L0.5910.69
138_W141_A0.5910.69
31_D206_P0.5890.69
10_T65_C0.5870.69
78_N122_M0.5870.69
164_H168_N0.5850.68
135_N141_A0.5800.68
144_T199_A0.5790.68
123_V127_C0.5770.67
115_P181_G0.5760.67
15_Q88_I0.5750.67
26_E33_L0.5740.67
52_S56_V0.5740.67
119_V159_A0.5740.67
34_S38_G0.5720.67
22_Q203_L0.5720.67
82_V229_W0.5700.66
158_L208_F0.5690.66
222_I225_G0.5680.66
139_D249_I0.5680.66
79_M88_I0.5670.66
116_R120_A0.5640.66
8_A11_R0.5640.66
201_V205_V0.5630.65
166_Q216_D0.5600.65
214_V221_H0.5600.65
107_S138_W0.5590.65
173_A204_L0.5560.65
50_I55_I0.5550.64
40_A99_Y0.5540.64
160_Q191_N0.5530.64
234_L238_A0.5490.64
77_I176_A0.5480.63
177_T188_T0.5460.63
27_S127_C0.5450.63
77_I147_A0.5440.63
223_N227_A0.5430.63
25_A236_T0.5430.63
31_D54_A0.5420.63
23_H85_V0.5420.63
21_L71_K0.5400.62
61_K142_V0.5390.62
204_L239_T0.5370.62
44_D92_A0.5360.62
15_Q85_V0.5350.62
19_F34_S0.5340.61
192_T197_M0.5340.61
177_T180_S0.5330.61
84_E98_D0.5320.61
184_L189_F0.5310.61
144_T171_L0.5300.61
155_R168_N0.5300.61
26_E32_E0.5270.60
36_R86_Q0.5260.60
98_D104_K0.5260.60
17_G130_F0.5250.60
111_P139_D0.5240.60
52_S232_A0.5230.60
87_H128_A0.5220.60
69_T133_L0.5220.60
131_C141_A0.5210.60
53_N75_R0.5200.59
172_T236_T0.5190.59
25_A31_D0.5180.59
16_C102_V0.5160.59
150_T179_I0.5150.59
14_I34_S0.5140.59
99_Y138_W0.5140.59
35_S48_S0.5130.58
17_G21_L0.5130.58
158_L171_L0.5130.58
29_L215_A0.5130.58
39_R44_D0.5120.58
175_A182_L0.5120.58
86_Q212_N0.5110.58
139_D191_N0.5110.58
167_I218_F0.5100.58
110_Q185_Q0.5090.58
51_S71_K0.5070.58
239_T246_A0.5060.57
58_T81_V0.5050.57
152_M201_V0.5030.57
64_Q101_G0.5020.57
213_A236_T0.5020.57
49_S71_K0.5010.57
184_L196_A0.5000.56
129_C148_S0.5000.56
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1ua4A 1 0.5117 26.3 0.949 Contact Map
1rfzA 4 0.5156 25.2 0.949 Contact Map
3bz6A 1 0.457 23 0.95 Contact Map
1wozA 3 0.4336 20.4 0.951 Contact Map
1l2lA 1 0.5508 18.6 0.952 Contact Map
4b8rA 1 0.5781 15.8 0.954 Contact Map
1nogA 4 0.418 12.3 0.956 Contact Map
3m66A 1 0.457 10.9 0.957 Contact Map
2idxA 3 0.4023 9 0.959 Contact Map
1z84A 2 0.3477 9 0.959 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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