GREMLIN Database
YJIX - Uncharacterized protein YjiX
UniProt: P0ADC8 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12585
Length: 67 (62)
Sequences: 276 (152)
Seq/√Len: 19.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
43_S46_E4.4721.00
48_F52_Q3.7301.00
11_Y14_Q2.6310.98
15_A18_M2.3450.96
30_E34_T2.2240.94
23_P56_Y2.1830.94
51_R57_G1.8120.85
16_A26_D1.7280.82
23_P51_R1.6210.78
44_Y51_R1.5120.72
14_Q53_N1.4900.71
32_M39_K1.4790.71
4_N34_T1.3950.66
22_I64_M1.3550.64
4_N41_Y1.2780.59
9_K12_L1.2490.57
4_N9_K1.2450.57
19_L65_R1.2100.55
30_E38_D1.1770.53
11_Y44_Y1.1690.52
12_L57_G1.1600.52
58_G63_G1.1180.49
57_G67_C1.0970.48
49_R57_G1.0940.47
30_E40_P1.0570.45
50_E67_C1.0510.45
20_I49_R1.0490.44
54_A58_G1.0270.43
24_D33_K1.0080.42
48_F67_C0.9920.41
58_G64_M0.9680.39
12_L26_D0.9610.39
24_D65_R0.9540.39
38_D42_M0.9340.37
8_A34_T0.9250.37
10_K30_E0.9060.36
41_Y56_Y0.8970.35
22_I52_Q0.8690.34
27_N38_D0.8560.33
20_I38_D0.8530.33
46_E53_N0.8470.32
15_A19_L0.8470.32
42_M49_R0.8410.32
26_D44_Y0.8370.32
5_L20_I0.8190.31
37_P54_A0.8180.31
9_K13_G0.8040.30
13_G22_I0.8010.30
20_I53_N0.8010.30
34_T40_P0.8000.30
44_Y50_E0.7990.30
35_N45_E0.7930.29
6_G39_K0.7850.29
5_L16_A0.7700.28
23_P55_R0.7580.28
39_K50_E0.7510.27
7_Q26_D0.7450.27
10_K44_Y0.7370.27
17_K24_D0.7240.26
10_K39_K0.7180.26
15_A22_I0.7100.25
6_G30_E0.7060.25
16_A24_D0.7040.25
37_P52_Q0.7030.25
9_K43_S0.6930.24
19_L42_M0.6910.24
16_A51_R0.6870.24
46_E49_R0.6840.24
51_R67_C0.6780.24
23_P48_F0.6780.24
22_I56_Y0.6690.23
52_Q57_G0.6660.23
30_E33_K0.6430.22
14_Q24_D0.6330.22
8_A35_N0.6260.21
29_V41_Y0.6240.21
7_Q30_E0.6130.21
41_Y65_R0.6030.20
22_I35_N0.6000.20
32_M54_A0.5990.20
8_A45_E0.5970.20
7_Q11_Y0.5760.19
54_A64_M0.5730.19
12_L15_A0.5610.19
26_D62_G0.5290.18
15_A24_D0.5260.17
32_M38_D0.5250.17
7_Q16_A0.5120.17
43_S56_Y0.5050.17
53_N64_M0.5040.17
42_M51_R0.5030.17
50_E57_G0.5000.16
16_A63_G0.5000.16
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4tpsB 1 0.9552 18.8 0.912 Contact Map
4s28A 2 0.9403 9 0.924 Contact Map
2im9A 1 0.9104 8.9 0.924 Contact Map
2r5oA 3 0.4328 7.8 0.926 Contact Map
2iw0A 1 0.5224 7.2 0.927 Contact Map
3epoA 2 0.9403 6.7 0.928 Contact Map
4q68A 1 0.8209 6.3 0.929 Contact Map
2z4sA 1 0 6.1 0.929 Contact Map
3hkmA 1 0.3433 5.7 0.93 Contact Map
3qtmA 1 0.4925 5.3 0.931 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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