GREMLIN Database
YAJG - Uncharacterized lipoprotein YajG
UniProt: P0ADA5 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12182
Length: 192 (181)
Sequences: 300 (202)
Seq/√Len: 15.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
80_L105_I3.5780.99
109_Q126_K3.0070.98
61_V162_I2.8860.97
49_G81_Q2.7320.96
85_E107_V2.5160.94
147_A173_T2.4680.93
103_L133_A2.4530.93
59_A112_A2.3590.92
88_M129_I2.3490.91
108_S130_A2.2730.90
80_L107_V2.2470.89
127_A166_V2.2080.89
6_L11_A2.0860.85
39_S150_N2.0600.85
13_F142_T2.0540.84
35_Q86_K2.0250.84
89_T95_V2.0210.83
58_L166_V1.9220.80
68_V133_A1.9130.80
133_A146_R1.8750.78
87_Q178_S1.8740.78
42_G80_L1.7940.75
112_A162_I1.7740.74
82_E86_K1.7150.72
47_I172_D1.6740.70
35_Q83_V1.6690.70
68_V126_K1.6530.69
105_I131_I1.6500.69
99_G155_F1.6360.68
19_A110_L1.6270.68
61_V143_K1.5960.66
121_Y165_A1.5790.65
141_M173_T1.5530.64
87_Q157_A1.5240.62
105_I129_I1.5230.62
80_L92_G1.5100.62
11_A16_A1.4730.60
33_L105_I1.4730.60
67_I141_M1.4600.59
27_V84_L1.4600.59
25_I167_N1.4510.58
44_T129_I1.4310.57
49_G84_L1.4190.57
16_A46_S1.4170.57
112_A143_K1.3900.55
26_E128_D1.3800.55
125_T143_K1.3730.54
84_L131_I1.3710.54
133_A183_I1.3180.51
59_A157_A1.2950.50
6_L39_S1.2910.50
55_D111_Y1.2830.49
112_A157_A1.2770.49
112_A123_I1.2690.48
15_L108_S1.2680.48
14_M17_G1.2590.48
10_V109_Q1.2520.47
34_P58_L1.2430.47
31_I88_M1.2320.46
12_L131_I1.2310.46
121_Y154_A1.2290.46
84_L88_M1.2260.46
111_Y183_I1.2170.45
142_T173_T1.2150.45
31_I171_T1.1990.44
7_F13_F1.1900.44
107_V110_L1.1840.44
96_G100_P1.1730.43
17_G167_N1.1720.43
58_L127_A1.1690.43
8_P14_M1.1670.43
135_A186_F1.1500.42
146_R185_E1.1500.42
155_F179_Q1.1460.41
105_I177_M1.1440.41
14_M27_V1.1410.41
150_N181_T1.1260.40
117_G169_V1.1180.40
25_I87_Q1.1160.40
125_T166_V1.1130.40
96_G105_I1.1130.40
63_R112_A1.1100.40
114_V121_Y1.1090.39
30_T179_Q1.1080.39
49_G77_R1.0940.39
9_L54_T1.0820.38
30_T48_N1.0820.38
79_L83_V1.0790.38
45_V133_A1.0770.38
10_V21_P1.0710.37
11_A73_S1.0700.37
80_L103_L1.0700.37
93_Y162_I1.0670.37
59_A178_S1.0550.37
28_S167_N1.0520.36
6_L136_Q1.0450.36
102_N145_Y1.0390.36
17_G137_N1.0330.35
82_E94_M1.0320.35
23_T153_G1.0310.35
140_K144_N1.0300.35
72_A132_I1.0200.35
80_L85_E1.0190.35
159_N162_I1.0170.35
58_L170_L1.0160.35
95_V103_L1.0130.34
23_T59_A1.0030.34
14_M73_S1.0010.34
55_D119_V0.9980.34
30_T122_N0.9930.33
15_L56_Q0.9770.33
19_A145_Y0.9720.32
154_A175_A0.9660.32
59_A162_I0.9630.32
93_Y184_H0.9600.32
23_T162_I0.9490.31
56_Q140_K0.9480.31
143_K180_D0.9440.31
114_V157_A0.9280.30
145_Y180_D0.9210.30
112_A121_Y0.9200.30
30_T115_S0.9180.30
25_I163_A0.9160.30
48_N98_N0.9120.30
48_N102_N0.9120.30
148_S173_T0.9110.29
61_V120_R0.9040.29
104_Q145_Y0.8950.29
86_K177_M0.8940.29
22_P68_V0.8930.29
27_V167_N0.8920.29
36_Q101_V0.8860.28
8_P54_T0.8820.28
149_Y163_A0.8820.28
100_P183_I0.8810.28
13_F131_I0.8780.28
35_Q131_I0.8690.28
25_I58_L0.8640.27
12_L16_A0.8640.27
15_L114_V0.8620.27
26_E160_K0.8270.26
22_P97_P0.8150.25
52_Q106_I0.8140.25
109_Q155_F0.8110.25
66_Q115_S0.8020.25
45_V188_K0.8010.25
100_P107_V0.7950.24
7_F181_T0.7920.24
57_A186_F0.7890.24
145_Y169_V0.7890.24
17_G101_V0.7880.24
157_A178_S0.7880.24
8_P33_L0.7870.24
29_P110_L0.7850.24
9_L19_A0.7830.24
100_P124_A0.7810.24
55_D77_R0.7760.24
11_A99_G0.7740.23
24_T75_D0.7720.23
80_L145_Y0.7720.23
15_L180_D0.7710.23
165_A176_D0.7630.23
95_V184_H0.7610.23
77_R81_Q0.7570.23
15_L18_C0.7500.23
27_V182_S0.7460.22
73_S110_L0.7450.22
91_R169_V0.7420.22
177_M186_F0.7250.22
41_M118_N0.7250.22
74_R94_M0.7160.21
8_P12_L0.7070.21
23_T121_Y0.7040.21
18_C51_D0.7030.21
89_T100_P0.7000.21
107_V147_A0.6980.21
31_I165_A0.6930.20
74_R91_R0.6930.20
23_T156_Q0.6910.20
63_R67_I0.6900.20
80_L151_V0.6860.20
128_D146_R0.6770.20
167_N183_I0.6770.20
71_T172_D0.6760.20
60_K147_A0.6750.20
126_K155_F0.6720.20
16_A42_G0.6670.19
34_P129_I0.6650.19
39_S152_E0.6630.19
89_T137_N0.6600.19
143_K177_M0.6590.19
36_Q103_L0.6520.19
101_V174_I0.6500.19
153_G186_F0.6480.19
27_V82_E0.6450.19
126_K148_S0.6420.19
121_Y153_G0.6390.18
59_A93_Y0.6380.18
102_N136_Q0.6340.18
31_I174_I0.6340.18
72_A116_Q0.6310.18
94_M179_Q0.6290.18
107_V174_I0.6270.18
69_T156_Q0.6270.18
35_Q179_Q0.6220.18
122_N132_I0.6220.18
112_A127_A0.6180.18
86_K90_A0.6150.18
125_T162_I0.6140.18
112_A153_G0.6130.18
62_T66_Q0.6130.18
50_A106_I0.6120.18
32_T185_E0.6120.18
125_T157_A0.6070.17
10_V54_T0.6060.17
114_V154_A0.6040.17
42_G126_K0.6020.17
130_A179_Q0.5990.17
55_D104_Q0.5970.17
45_V99_G0.5950.17
19_A107_V0.5930.17
23_T45_V0.5930.17
101_V154_A0.5900.17
72_A140_K0.5880.17
27_V166_V0.5870.17
59_A87_Q0.5870.17
128_D148_S0.5860.17
11_A41_M0.5850.17
69_T127_A0.5820.17
146_R177_M0.5810.17
143_K162_I0.5800.17
84_L143_K0.5800.17
50_A158_S0.5790.17
107_V143_K0.5770.16
61_V112_A0.5710.16
174_I183_I0.5650.16
45_V147_A0.5650.16
93_Y169_V0.5620.16
16_A129_I0.5610.16
133_A186_F0.5610.16
42_G150_N0.5600.16
46_S96_G0.5600.16
112_A125_T0.5560.16
129_I186_F0.5520.16
27_V185_E0.5500.16
147_A169_V0.5360.15
162_I176_D0.5360.15
116_Q161_N0.5320.15
10_V168_S0.5310.15
114_V143_K0.5300.15
89_T118_N0.5300.15
63_R68_V0.5270.15
49_G136_Q0.5260.15
45_V119_V0.5240.15
106_I137_N0.5240.15
36_Q105_I0.5230.15
24_T174_I0.5220.15
110_L166_V0.5180.15
120_R152_E0.5170.15
35_Q85_E0.5140.15
116_Q150_N0.5130.15
40_L59_A0.5120.15
91_R112_A0.5110.15
18_C53_R0.5100.15
76_L144_N0.5080.14
60_K111_Y0.5040.14
17_G151_V0.5030.14
118_N154_A0.5020.14
86_K115_S0.5020.14
149_Y186_F0.5020.14
88_M131_I0.5010.14
95_V161_N0.5000.14
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4n4rB 1 0.6771 96.6 0.865 Contact Map
2iqiA 1 0.8385 96.5 0.866 Contact Map
3zbiC 1 0.1406 95.3 0.879 Contact Map
4fybB 1 0.7292 85.4 0.906 Contact Map
4av2M 1 0.375 70.4 0.918 Contact Map
2hyxA 2 0.8906 58.2 0.925 Contact Map
4qflA 1 0.7708 55.3 0.926 Contact Map
3j6da 3 0.7292 51.3 0.927 Contact Map
4jg9A 2 0.526 49.4 0.928 Contact Map
4yv7A 1 0.5156 44.2 0.93 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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