GREMLIN Database
PBP2 - Penicillin-binding protein 2
UniProt: P0AD65 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10606
Length: 633 (518)
Sequences: 15975 (11570)
Seq/√Len: 508.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
575_T588_A3.3761.00
275_V587_V3.3691.00
466_S588_A3.2601.00
516_K577_F3.2261.00
489_E492_K3.2251.00
273_V607_I3.1521.00
207_K211_E3.0811.00
206_G209_G3.0531.00
282_G485_M3.0381.00
282_G482_H2.9921.00
262_I273_V2.8811.00
381_T521_G2.8311.00
200_A210_I2.7771.00
343_A403_R2.7511.00
139_T142_Q2.7481.00
477_I505_G2.7421.00
266_L271_A2.7271.00
278_P586_A2.7011.00
378_L388_A2.6051.00
351_T377_R2.5861.00
160_G170_S2.5331.00
520_Y540_K2.5271.00
277_D280_T2.5201.00
543_A574_M2.5091.00
275_V607_I2.4031.00
342_S511_Y2.3831.00
251_Y486_S2.3771.00
406_E410_K2.3581.00
381_T517_D2.3461.00
382_R386_E2.3171.00
277_D282_G2.2301.00
467_K478_V2.2211.00
605_R609_D2.1781.00
383_S391_F2.1741.00
335_Y468_A2.1521.00
385_E527_N2.1071.00
261_Y610_H2.1051.00
70_I78_P2.1051.00
350_T398_D2.0851.00
276_T466_S2.0771.00
57_N61_L2.0631.00
385_E521_G2.0591.00
382_R385_E2.0361.00
265_L606_Q2.0351.00
284_L585_V2.0191.00
347_T350_T2.0141.00
332_V408_M2.0131.00
375_H388_A2.0131.00
353_F377_R1.9921.00
200_A207_K1.9681.00
379_N382_R1.9411.00
258_L611_I1.9301.00
403_R406_E1.9131.00
339_S407_W1.9041.00
210_I214_Y1.8981.00
260_Q264_T1.8801.00
338_V511_Y1.8771.00
277_D584_Q1.8691.00
279_R584_Q1.8581.00
342_S508_H1.8561.00
585_V611_I1.8531.00
475_D513_E1.8181.00
359_Q366_R1.8131.00
249_D488_A1.8111.00
508_H511_Y1.8051.00
467_K481_P1.7981.00
263_E287_V1.7931.00
269_S593_N1.7901.00
262_I607_I1.7781.00
276_T481_P1.7761.00
509_S513_E1.7721.00
38_N41_N1.7651.00
251_Y485_M1.7651.00
604_M608_L1.7591.00
258_L284_L1.7581.00
370_W596_A1.7491.00
273_V589_M1.7421.00
542_A577_F1.7391.00
475_D509_S1.7301.00
462_P588_A1.7271.00
507_I512_W1.7151.00
520_Y524_N1.7151.00
262_I285_A1.7081.00
261_Y265_L1.7001.00
576_A604_M1.7001.00
396_A452_G1.6981.00
470_M586_A1.6871.00
197_A214_Y1.6871.00
521_G527_N1.6821.00
480_V500_H1.6781.00
277_D284_L1.6551.00
378_L382_R1.6521.00
334_P472_L1.6421.00
275_V585_V1.6341.00
78_P81_L1.6261.00
352_L398_D1.6111.00
469_L519_M1.5841.00
342_S410_K1.5791.00
517_D520_Y1.5751.00
589_M604_M1.5661.00
357_W366_R1.5571.00
57_N60_K1.5471.00
69_G198_N1.5341.00
274_V463_I1.5311.00
328_P460_A1.5281.00
81_L84_T1.5221.00
486_S496_W1.5181.00
59_I159_K1.5161.00
283_V483_L1.5121.00
394_Q398_D1.5071.00
346_I380_V1.4941.00
74_R282_G1.4871.00
469_L575_T1.4761.00
591_L603_L1.4591.00
396_A404_L1.4571.00
384_L518_G1.4511.00
413_Y460_A1.4441.00
338_V507_I1.4411.00
576_A608_L1.4331.00
267_A289_T1.4311.00
369_D388_A1.4271.00
253_T282_G1.4201.00
475_D516_K1.4201.00
383_S392_F1.4121.00
338_V411_F1.4121.00
117_A120_R1.4101.00
472_L515_A1.4081.00
51_Q54_S1.4081.00
266_L287_V1.4041.00
116_I120_R1.4001.00
505_G509_S1.3981.00
471_I478_V1.3971.00
405_S409_G1.3951.00
354_D388_A1.3951.00
523_A543_A1.3881.00
197_A210_I1.3811.00
331_T465_M1.3771.00
232_R235_V1.3731.00
465_M575_T1.3731.00
523_A541_I1.3551.00
264_T610_H1.3551.00
348_R518_G1.3531.00
72_Y249_D1.3441.00
493_Q496_W1.3441.00
61_L204_D1.3391.00
273_V587_V1.3301.00
251_Y488_A1.3281.00
58_R61_L1.3281.00
550_V592_E1.3241.00
473_I542_A1.3231.00
473_I577_F1.3191.00
52_T60_K1.3131.00
72_Y141_V1.3071.00
587_V607_I1.3071.00
355_P394_Q1.3041.00
274_V462_P1.3001.00
359_Q362_G1.2951.00
578_A612_M1.2891.00
198_N201_A1.2861.00
133_P136_T1.2851.00
276_T586_A1.2821.00
474_N479_K1.2821.00
340_A395_V1.2811.00
69_G202_T1.2791.00
488_A493_Q1.2741.00
258_L285_A1.2731.00
180_S207_K1.2721.00
610_H613_L1.2711.00
348_R514_L1.2661.00
411_F507_I1.2621.00
214_Y250_I1.2561.00
536_S605_R1.2521.00
320_R594_G1.2491.00
368_R372_K1.2451.00
142_Q145_R1.2431.00
253_T482_H1.2401.00
262_I287_V1.2371.00
318_V324_G1.2371.00
341_L518_G1.2361.00
402_D406_E1.2361.00
230_N234_R1.2361.00
337_A392_F1.2341.00
276_T470_M1.2291.00
156_V165_Y1.2241.00
40_Y44_I1.2241.00
478_V504_V1.2201.00
198_N202_T1.2171.00
587_V608_L1.2131.00
257_K614_G1.2131.00
358_W397_Y1.2021.00
407_W410_K1.2011.00
70_I249_D1.1991.00
513_E516_K1.1951.00
482_H497_V1.1921.00
286_L321_A1.1901.00
77_I257_K1.1901.00
88_I96_D1.1881.00
524_N527_N1.1861.00
465_M573_L1.1801.00
343_A407_W1.1681.00
66_P222_T1.1671.00
100_Q104_A1.1651.00
516_K542_A1.1641.00
274_V466_S1.1631.00
612_M615_D1.1601.00
397_Y449_I1.1591.00
380_V391_F1.1581.00
58_R172_L1.1571.00
346_I350_T1.1541.00
521_G524_N1.1471.00
181_K184_D1.1471.00
228_E232_R1.1461.00
46_R49_D1.1351.00
231_N235_V1.1261.00
338_V515_A1.1261.00
400_G403_R1.1251.00
66_P198_N1.1251.00
128_R131_S1.1211.00
37_A41_N1.1211.00
354_D369_D1.1181.00
138_L142_Q1.1121.00
116_I121_K1.1111.00
117_A121_K1.1101.00
345_V398_D1.1101.00
407_W411_F1.1091.00
38_N42_L1.1051.00
390_T394_Q1.1041.00
215_E219_H1.1001.00
275_V611_I1.0951.00
52_T145_R1.0941.00
278_P585_V1.0911.00
103_D113_D1.0861.00
589_M603_L1.0851.00
410_K504_V1.0821.00
342_S407_W1.0811.00
409_G415_H1.0811.00
466_S586_A1.0771.00
522_V530_A1.0771.00
52_T141_V1.0731.00
523_A574_M1.0681.00
527_N531_H1.0591.00
375_H386_E1.0591.00
74_R284_L1.0581.00
168_Y256_L1.0531.00
286_L319_N1.0501.00
486_S493_Q1.0481.00
266_L273_V1.0461.00
265_L603_L1.0461.00
512_W516_K1.0451.00
55_N59_I1.0431.00
74_R135_K1.0411.00
335_Y411_F1.0381.00
104_A107_S1.0381.00
338_V407_W1.0351.00
72_Y251_Y1.0341.00
477_I503_P1.0331.00
472_L516_K1.0321.00
541_I578_A1.0291.00
550_V593_N1.0241.00
479_K503_P1.0241.00
378_L391_F1.0211.00
341_L514_L1.0211.00
510_G514_L1.0201.00
70_I81_L1.0181.00
338_V512_W1.0121.00
343_A399_M1.0121.00
63_P176_I1.0121.00
261_Y264_T1.0111.00
516_K519_M1.0091.00
274_V286_L1.0041.00
334_P519_M1.0001.00
371_K375_H1.0001.00
473_I586_A1.0001.00
479_K499_P0.9991.00
248_H494_V0.9951.00
388_A391_F0.9911.00
138_L146_F0.9901.00
278_P470_M0.9881.00
334_P469_L0.9851.00
232_R236_I0.9831.00
406_E409_G0.9831.00
371_K374_G0.9811.00
173_T291_S0.9801.00
598_P601_G0.9781.00
92_P95_V0.9771.00
65_A204_D0.9731.00
335_Y408_M0.9711.00
256_L260_Q0.9671.00
211_E215_E0.9651.00
113_D117_A0.9651.00
572_K597_G0.9611.00
606_Q609_D0.9611.00
257_K260_Q0.9611.00
337_A380_V0.9601.00
265_L610_H0.9601.00
60_K141_V0.9591.00
334_P384_L0.9551.00
455_Q549_Q0.9521.00
276_T467_K0.9491.00
460_A465_M0.9491.00
467_K480_V0.9481.00
381_T518_G0.9481.00
319_N322_T0.9441.00
462_P466_S0.9391.00
579_P584_Q0.9391.00
272_A462_P0.9381.00
393_Y453_I0.9361.00
271_A591_L0.9341.00
197_A201_A0.9331.00
352_L391_F0.9321.00
59_I63_P0.9311.00
403_R407_W0.9301.00
258_L275_V0.9291.00
52_T55_N0.9271.00
597_G601_G0.9261.00
587_V604_M0.9261.00
378_L386_E0.9251.00
68_R74_R0.9241.00
169_G293_D0.9231.00
33_G37_A0.9211.00
338_V472_L0.9201.00
375_H378_L0.9171.00
414_G464_Q0.9161.00
164_R168_Y0.9161.00
380_V395_V0.9151.00
407_W507_I0.9151.00
175_V254_L0.9151.00
151_Y179_V0.9131.00
511_Y515_A0.9131.00
207_K210_I0.9131.00
351_T379_N0.9121.00
413_Y468_A0.9121.00
572_K600_V0.9121.00
133_P137_N0.9111.00
210_I252_L0.9101.00
573_L590_I0.9081.00
336_V404_L0.9061.00
149_N152_R0.9061.00
584_Q618_T0.9031.00
97_N100_Q0.9021.00
70_I73_D0.9001.00
127_H130_T0.8981.00
233_G236_I0.8951.00
336_V452_G0.8941.00
524_N535_A0.8941.00
591_L600_V0.8941.00
415_H464_Q0.8901.00
115_D119_F0.8891.00
584_Q615_D0.8891.00
208_L212_R0.8861.00
530_A545_S0.8851.00
346_I395_V0.8841.00
354_D375_H0.8811.00
40_Y43_Q0.8801.00
404_L408_M0.8791.00
140_E144_A0.8731.00
225_E228_E0.8691.00
221_Q245_Q0.8671.00
56_E59_I0.8661.00
131_S136_T0.8661.00
571_H590_I0.8661.00
578_A608_L0.8631.00
60_K72_Y0.8621.00
272_A321_A0.8611.00
358_W394_Q0.8611.00
211_E214_Y0.8591.00
484_L487_T0.8581.00
262_I275_V0.8551.00
72_Y78_P0.8551.00
63_P153_F0.8541.00
444_Y447_D0.8531.00
278_P473_I0.8531.00
230_N233_G0.8521.00
352_L394_Q0.8491.00
270_R320_R0.8481.00
129_F132_I0.8471.00
89_E92_P0.8441.00
362_G365_K0.8411.00
360_L449_I0.8411.00
74_R255_D0.8411.00
380_V518_G0.8401.00
135_K142_Q0.8391.00
450_P455_Q0.8391.00
231_N234_R0.8381.00
327_P548_A0.8361.00
450_P456_G0.8341.00
98_V102_L0.8331.00
99_Q117_A0.8311.00
227_V230_N0.8301.00
152_R155_G0.8301.00
114_D118_A0.8291.00
128_R132_I0.8291.00
341_L511_Y0.8271.00
273_V603_L0.8211.00
396_A401_I0.8201.00
517_D521_G0.8181.00
369_D375_H0.8131.00
112_T115_D0.8121.00
511_Y514_L0.8121.00
154_P186_D0.8111.00
217_V248_H0.8111.00
209_G212_R0.8091.00
585_V615_D0.8081.00
205_I210_I0.8071.00
530_A533_Y0.8051.00
523_A530_A0.8051.00
228_E253_T0.8031.00
59_I172_L0.7981.00
253_T485_M0.7951.00
262_I265_L0.7941.00
466_S575_T0.7921.00
286_L322_T0.7921.00
331_T575_T0.7921.00
357_W360_L0.7921.00
461_T464_Q0.7911.00
40_Y45_V0.7901.00
200_A214_Y0.7891.00
356_G374_G0.7891.00
540_K617_N0.7881.00
258_L607_I0.7871.00
29_L33_G0.7851.00
283_V463_I0.7831.00
200_A205_I0.7831.00
186_D207_K0.7821.00
197_A200_A0.7811.00
272_A590_I0.7801.00
84_T96_D0.7801.00
22_L26_L0.7781.00
105_L146_F0.7751.00
514_L517_D0.7751.00
23_V27_G0.7741.00
286_L483_L0.7741.00
530_A574_M0.7721.00
513_E517_D0.7721.00
371_K388_A0.7671.00
608_L612_M0.7671.00
399_M403_R0.7661.00
335_Y465_M0.7651.00
127_H131_S0.7641.00
512_W515_A0.7631.00
533_Y601_G0.7631.00
49_D53_R0.7611.00
231_N236_I0.7611.00
111_L116_I0.7601.00
384_L519_M0.7581.00
55_N60_K0.7561.00
229_V232_R0.7501.00
87_Q161_Y0.7501.00
514_L518_G0.7461.00
447_D450_P0.7441.00
382_R527_N0.7431.00
354_D376_G0.7401.00
237_R240_K0.7401.00
510_G513_E0.7391.00
280_T479_K0.7371.00
106_R134_V0.7361.00
255_D258_L0.7351.00
67_S246_A0.7351.00
374_G390_T0.7331.00
462_P573_L0.7331.00
127_H132_I0.7331.00
88_I138_L0.7311.00
52_T72_Y0.7311.00
394_Q397_Y0.7301.00
465_M588_A0.7281.00
160_G164_R0.7261.00
88_I92_P0.7251.00
210_I250_I0.7251.00
226_E229_V0.7241.00
335_Y413_Y0.7221.00
543_A601_G0.7221.00
413_Y465_M0.7221.00
30_L34_V0.7211.00
65_A202_T0.7201.00
130_T133_P0.7201.00
135_K143_V0.7191.00
263_E267_A0.7181.00
515_A518_G0.7161.00
257_K261_Y0.7161.00
274_V588_A0.7141.00
341_L515_A0.7131.00
235_V238_Q0.7131.00
550_V570_D0.7121.00
47_F51_Q0.7111.00
280_T482_H0.7111.00
326_Y571_H0.7101.00
50_Y55_N0.7071.00
340_A346_I0.7071.00
186_D189_R0.7051.00
112_T116_I0.7031.00
346_I398_D0.7021.00
463_I481_P0.6971.00
41_N46_R0.6971.00
392_F395_V0.6951.00
101_T104_A0.6951.00
469_L586_A0.6941.00
353_F394_Q0.6921.00
75_N79_L0.6911.00
541_I604_M0.6911.00
79_L82_N0.6911.00
63_P179_V0.6911.00
519_M577_F0.6901.00
172_L254_L0.6891.00
274_V321_A0.6871.00
39_L43_Q0.6851.00
229_V233_G0.6841.00
55_N58_R0.6821.00
103_D107_S0.6821.00
148_V151_Y0.6811.00
607_I611_I0.6801.00
378_L383_S0.6791.00
47_F50_Y0.6781.00
337_A384_L0.6771.00
539_Y584_Q0.6771.00
328_P332_V0.6771.00
470_M479_K0.6751.00
572_K599_A0.6751.00
339_S343_A0.6741.00
329_A548_A0.6741.00
113_D116_I0.6741.00
58_R209_G0.6731.00
64_I72_Y0.6721.00
32_T36_I0.6711.00
41_N45_V0.6711.00
345_V403_R0.6701.00
126_S129_F0.6671.00
520_Y523_A0.6661.00
475_D512_W0.6661.00
225_E229_V0.6641.00
254_L483_L0.6621.00
375_H382_R0.6611.00
336_V396_A0.6601.00
279_R475_D0.6591.00
62_V199_Y0.6591.00
101_T153_F0.6591.00
265_L607_I0.6581.00
228_E231_N0.6581.00
212_R216_D0.6581.00
384_L392_F0.6571.00
474_N477_I0.6561.00
262_I271_A0.6561.00
599_A602_T0.6561.00
126_S130_T0.6551.00
536_S609_D0.6541.00
381_T385_E0.6541.00
31_L35_L0.6531.00
46_R50_Y0.6531.00
227_V232_R0.6521.00
522_V529_T0.6521.00
115_D118_A0.6501.00
360_L397_Y0.6481.00
131_S135_K0.6481.00
174_H177_G0.6471.00
467_K470_M0.6471.00
23_V26_L0.6461.00
28_I32_T0.6461.00
64_I204_D0.6461.00
589_M600_V0.6461.00
79_L83_R0.6461.00
223_G226_E0.6441.00
541_I574_M0.6421.00
27_G31_L0.6401.00
172_L175_V0.6401.00
39_L42_L0.6401.00
597_G602_T0.6371.00
98_V107_S0.6371.00
606_Q610_H0.6371.00
369_D374_G0.6361.00
574_M604_M0.6351.00
345_V399_M0.6341.00
390_T393_Y0.6341.00
19_R23_V0.6341.00
328_P456_G0.6341.00
153_F159_K0.6321.00
332_V336_V0.6321.00
99_Q103_D0.6321.00
258_L261_Y0.6311.00
591_L599_A0.6301.00
411_F468_A0.6291.00
477_I504_V0.6281.00
326_Y592_E0.6281.00
129_F133_P0.6241.00
332_V335_Y0.6241.00
571_H592_E0.6241.00
572_K598_P0.6231.00
516_K520_Y0.6201.00
24_A28_I0.6201.00
328_P465_M0.6191.00
411_F471_I0.6191.00
467_K471_I0.6181.00
327_P571_H0.6171.00
83_R87_Q0.6171.00
386_E527_N0.6171.00
337_A518_G0.6171.00
531_H535_A0.6161.00
131_S134_V0.6151.00
345_V395_V0.6151.00
385_E522_V0.6131.00
37_A40_Y0.6131.00
180_S185_K0.6121.00
70_I80_A0.6091.00
577_F586_A0.6081.00
405_S451_V0.6050.99
275_V278_P0.6050.99
226_E240_K0.6050.99
328_P455_Q0.6040.99
339_S399_M0.6040.99
101_T105_L0.6030.99
35_L38_N0.6030.99
532_K601_G0.6030.99
89_E157_E0.6020.99
106_R110_D0.6020.99
214_Y217_V0.6010.99
238_Q241_E0.5990.99
539_Y617_N0.5990.99
396_A449_I0.5980.99
88_I156_V0.5980.99
345_V350_T0.5980.99
478_V506_D0.5980.99
352_L395_V0.5950.99
41_N44_I0.5950.99
91_M94_K0.5950.99
51_Q55_N0.5950.99
52_T56_E0.5950.99
77_I256_L0.5940.99
227_V235_V0.5940.99
341_L380_V0.5930.99
405_S447_D0.5920.99
608_L611_I0.5910.99
467_K479_K0.5870.99
242_V246_A0.5870.99
181_K202_T0.5850.99
572_K596_A0.5850.99
325_V464_Q0.5850.99
68_R71_I0.5850.99
164_R170_S0.5850.99
409_G414_G0.5840.99
248_H487_T0.5820.99
36_I40_Y0.5800.99
539_Y612_M0.5800.99
401_I448_T0.5800.99
173_T292_Y0.5800.99
83_R86_Y0.5790.99
283_V286_L0.5790.99
367_Y453_I0.5780.99
89_E95_V0.5780.99
463_I467_K0.5780.99
152_R157_E0.5770.99
355_P390_T0.5770.99
54_S57_N0.5770.99
578_A585_V0.5760.99
471_I506_D0.5740.99
257_K610_H0.5740.99
343_A346_I0.5730.99
132_I135_K0.5730.99
539_Y609_D0.5730.99
293_D296_L0.5720.99
235_V239_L0.5720.99
29_L36_I0.5690.99
260_Q263_E0.5690.99
402_D447_D0.5690.99
369_D390_T0.5690.99
508_H512_W0.5690.99
36_I43_Q0.5680.99
86_Y89_E0.5680.99
400_G448_T0.5660.99
276_T479_K0.5660.99
62_V65_A0.5650.99
51_Q145_R0.5640.99
214_Y484_L0.5630.99
102_L106_R0.5620.99
349_N381_T0.5620.99
507_I511_Y0.5610.99
348_R381_T0.5610.99
106_R109_V0.5600.99
354_D374_G0.5590.99
537_A605_R0.5580.99
322_T463_I0.5570.99
341_L346_I0.5570.99
250_I487_T0.5560.99
489_E494_V0.5560.99
365_K393_Y0.5560.99
116_I119_F0.5560.99
70_I82_N0.5560.99
199_Y215_E0.5550.99
200_A211_E0.5540.99
354_D378_L0.5530.99
39_L44_I0.5530.99
104_A108_V0.5510.99
223_G244_P0.5510.99
367_Y393_Y0.5510.99
213_Y422_A0.5510.99
132_I136_T0.5490.99
466_S470_M0.5490.99
578_A584_Q0.5490.99
76_G251_Y0.5480.99
331_T573_L0.5480.99
77_I128_R0.5470.99
259_Q263_E0.5460.99
118_A126_S0.5460.99
396_A451_V0.5460.99
533_Y536_S0.5450.99
392_F452_G0.5450.99
572_K591_L0.5450.99
453_I549_Q0.5450.99
358_W361_P0.5440.99
330_S333_K0.5440.99
83_R165_Y0.5430.99
168_Y171_A0.5430.99
130_T134_V0.5430.99
478_V481_P0.5420.99
205_I215_E0.5410.99
399_M404_L0.5410.99
522_V574_M0.5410.99
276_T283_V0.5400.99
279_R474_N0.5380.99
107_S113_D0.5360.99
228_E233_G0.5360.99
334_P515_A0.5350.99
473_I516_K0.5350.99
144_A148_V0.5350.99
535_A538_P0.5350.99
128_R135_K0.5350.99
482_H485_M0.5340.99
20_R24_A0.5340.99
270_R592_E0.5340.99
25_F29_L0.5330.99
276_T588_A0.5320.99
485_M496_W0.5320.99
480_V503_P0.5300.99
367_Y450_P0.5290.99
542_A579_P0.5290.99
291_S294_P0.5280.99
230_N236_I0.5280.99
523_A533_Y0.5280.99
345_V348_R0.5280.99
148_V159_K0.5270.99
87_Q91_M0.5270.99
523_A531_H0.5270.99
58_R228_E0.5270.99
337_A395_V0.5260.99
227_V231_N0.5260.99
242_V245_Q0.5260.99
585_V608_L0.5260.99
472_L577_F0.5250.99
385_E518_G0.5240.99
522_V528_G0.5240.99
102_L117_A0.5230.99
222_T225_E0.5220.99
288_S321_A0.5220.99
520_Y619_D0.5210.99
401_I451_V0.5210.99
220_G223_G0.5200.98
250_I484_L0.5190.98
88_I158_V0.5180.98
141_V145_R0.5170.98
47_F52_T0.5160.98
79_L132_I0.5160.98
183_N186_D0.5160.98
61_L224_Y0.5150.98
143_V147_A0.5120.98
140_E143_V0.5120.98
612_M617_N0.5090.98
228_E235_V0.5060.98
358_W393_Y0.5050.98
70_I74_R0.5050.98
224_Y230_N0.5050.98
272_A320_R0.5040.98
88_I91_M0.5040.98
38_N43_Q0.5040.98
269_S595_G0.5030.98
172_L263_E0.5030.98
143_V158_V0.5030.98
245_Q248_H0.5020.98
27_G34_V0.5020.98
536_S541_I0.5000.98
31_L34_V0.5000.98
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2wadA 1 0.7962 100 0.249 Contact Map
4ovdA 2 0.6461 100 0.251 Contact Map
4ye5A 1 0.7994 100 0.257 Contact Map
3equA 1 0.6603 100 0.261 Contact Map
3vskA 2 0.8246 100 0.276 Contact Map
3ue3A 1 0.6682 100 0.289 Contact Map
1qmeA 1 0.6635 100 0.29 Contact Map
3pbtA 1 0.7678 100 0.293 Contact Map
4bjpA 2 0.6335 100 0.293 Contact Map
1vqqA 1 0.8973 100 0.3 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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