GREMLIN Database
YFCZ - UPF0381 protein YfcZ
UniProt: P0AD33 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14129
Length: 94 (92)
Sequences: 136 (79)
Seq/√Len: 8.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
37_R41_E4.7860.99
52_R55_E4.6000.99
37_R67_E2.5730.79
31_S73_R2.3280.71
24_S34_F2.2700.69
9_T13_C2.0440.61
68_E73_R1.7680.49
44_L76_I1.7660.49
4_C11_V1.7590.49
18_G91_L1.6410.44
34_F43_T1.6390.44
8_E12_C1.5790.42
19_T25_D1.5590.41
4_C14_C1.5190.39
10_P13_C1.5100.39
11_V14_C1.4970.38
49_E53_S1.4760.38
6_A14_C1.4640.37
53_S87_L1.4480.36
36_N39_E1.4410.36
4_C9_T1.3930.34
5_S39_E1.3850.34
6_A13_C1.3800.34
38_A81_A1.3420.32
58_P61_I1.3320.32
11_V15_M1.3210.32
9_T14_C1.3050.31
56_S72_V1.2800.30
6_A15_M1.2640.30
12_C17_V1.2420.29
62_T79_T1.2250.28
38_A63_P1.2160.28
20_I91_L1.2100.28
33_V38_A1.2030.28
4_C15_M1.1910.27
31_S75_D1.1910.27
39_E45_A1.1880.27
25_D55_E1.1610.26
17_V91_L1.1450.26
9_T90_Q1.0950.24
37_R65_F1.0730.23
4_C19_T1.0650.23
6_A10_P1.0570.23
35_A54_V1.0520.23
34_F46_A1.0500.23
4_C13_C1.0470.23
43_T46_A1.0440.23
23_N93_L1.0360.22
28_A90_Q1.0220.22
12_C16_D1.0180.22
6_A9_T1.0110.22
36_N69_S0.9950.21
29_S77_D0.9460.20
49_E60_K0.9360.20
21_M81_A0.9350.20
30_Y33_V0.9340.20
7_D15_M0.9240.19
8_E14_C0.9110.19
72_V81_A0.8980.19
4_C10_P0.8950.19
7_D13_C0.8900.18
44_L78_F0.8850.18
64_T75_D0.8850.18
30_Y34_F0.8780.18
57_E69_S0.8630.18
9_T15_M0.8570.18
67_E81_A0.8410.17
34_F73_R0.8370.17
60_K64_T0.8310.17
3_K63_P0.8190.17
55_E90_Q0.8180.17
47_L78_F0.8120.17
67_E86_M0.8060.16
36_N65_F0.7770.16
65_F72_V0.7740.16
7_D10_P0.7720.16
37_R54_V0.7660.16
54_V92_G0.7640.15
7_D14_C0.7590.15
48_T59_C0.7560.15
5_S27_T0.7550.15
30_Y76_I0.7540.15
3_K21_M0.7460.15
21_M76_I0.7400.15
30_Y47_L0.7280.15
58_P71_G0.7250.15
48_T57_E0.7230.15
49_E57_E0.7180.14
7_D63_P0.7130.14
23_N57_E0.7100.14
15_M19_T0.7100.14
62_T75_D0.7080.14
60_K66_T0.6990.14
37_R75_D0.6860.14
10_P15_M0.6770.14
7_D11_V0.6750.14
21_M24_S0.6710.14
13_C93_L0.6690.14
31_S52_R0.6660.13
12_C78_F0.6620.13
49_E70_D0.6500.13
33_V68_E0.6490.13
52_R63_P0.6460.13
46_A54_V0.6430.13
29_S86_M0.6330.13
55_E59_C0.6300.13
10_P14_C0.6190.13
86_M93_L0.6140.12
33_V70_D0.6130.12
32_R73_R0.6130.12
20_I81_A0.6100.12
65_F76_I0.6090.12
30_Y53_S0.5990.12
16_D88_I0.5980.12
20_I49_E0.5980.12
28_A73_R0.5970.12
16_D91_L0.5950.12
25_D29_S0.5910.12
24_S83_E0.5860.12
21_M54_V0.5830.12
38_A70_D0.5760.12
6_A93_L0.5730.12
83_E87_L0.5720.12
25_D83_E0.5660.12
78_F88_I0.5640.12
55_E61_I0.5430.11
28_A93_L0.5420.11
24_S81_A0.5320.11
63_P69_S0.5310.11
9_T23_N0.5270.11
32_R43_T0.5240.11
79_T93_L0.5220.11
76_I81_A0.5210.11
45_A48_T0.5120.11
35_A75_D0.5100.11
19_T87_L0.5030.11
20_I32_R0.5000.11
17_V20_I0.5000.11
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2k3iA 1 1 100 0.232 Contact Map
2khdA 1 0.9681 100 0.323 Contact Map
2jz5A 1 0.8298 100 0.349 Contact Map
4xesA 1 0.9043 3.3 0.954 Contact Map
2d9qB 1 0.3511 2.8 0.956 Contact Map
3lq9A 1 0.6277 2.3 0.958 Contact Map
2ibfB 1 0.266 2.2 0.958 Contact Map
3ny7A 1 0.4681 2.1 0.959 Contact Map
1ha8A 1 0.2979 1.9 0.96 Contact Map
3b77A 4 0.8191 1.8 0.961 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0056 seconds.