YEJM - ECOLI - GREMLIN Contacts

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YEJM - Inner membrane protein YejM

UniProt:	P0AD27	Sequences: MVTHRQRYREKVSQMVSWGHWFALFNILLSLVIGSRYLFIADWPTTLAGRIYSYVSIIGHFSFLVFATYLLILFPLTFIVGSQRLMRFLSVILATAGMTLLLIDSEVFTRFHLHLNPIVWQLVINPDENEMARDWQLMFISVPVILLLELVFATWSWQKLRSLTRRRRFARPLAAFLFIAFIASHVVYIWADANFYRPITMQRANLPLSYPMTARRFLEKHGLLDAQEYQRRLIEQGNPDAVSVQYPLSELRYRDMGTGQNVLLITVDGLNYSRFEKQMPALAGFAEQNISFTRHMSSGNTTDNGIFGLFYGISPSYMDGILSTRTPAALITALNQQGYQLGLFSSDGFTSPLYRQALLSDFSMPSVRTQSDEQTATQWINWLGRYAQEDNRWFSWVSFNGTNIDDSNQQAFARKYSRAAGNVDDQINRVLNALRDSGKLDNTVVIITAGRGIPLSEEEETFDWSHGHLQVPLVIHWPGTPAQRINALTDHTDLMTTLMQRLLHVSTPASEYSQGQDLFNPQRRHYWVTAADNDTLAITTPKKTLVLNNNGKYRTYNLRGERVKDEKPQLSLLLQVLTDEKRFIAN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12049
Length:	586 (485)
Sequences:	4256 (3607)
Seq/√Len:	163.8

ECOLI - YEJM EPTC YHBX EPTA EPTB OPGE YIDJ YDEN ASLA
BACSU - YQGS LTAS1 LTAS2 YVGJ
HALSA - Q9HQ44 Q9HSV3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
293_T	486_N	5.941	1.00
281_A	428_N	5.911	1.00
500_Q	517_D	4.299	1.00
384_G	437_S	4.093	1.00
281_A	284_G	4.042	1.00
335_N	360_S	3.935	1.00
265_I	447_I	3.598	1.00
54_Y	57_I	3.376	1.00
263_L	445_V	3.336	1.00
489_T	518_L	3.217	1.00
262_V	503_L	3.034	1.00
267_V	270_L	2.974	1.00
464_W	467_G	2.923	1.00
295_H	489_T	2.820	1.00
53_S	57_I	2.719	1.00
288_Q	435_R	2.704	1.00
260_Q	442_N	2.687	1.00
27_I	30_S	2.668	1.00
351_S	354_Y	2.665	1.00
278_Q	283_A	2.640	1.00
261_N	443_T	2.637	1.00
428_N	432_N	2.623	1.00
380_I	433_A	2.603	1.00
432_N	435_R	2.586	1.00
262_V	334_L	2.564	1.00
340_Q	391_N	2.560	1.00
435_R	440_L	2.494	1.00
432_N	436_D	2.481	1.00
213_T	216_R	2.450	1.00
263_L	443_T	2.397	1.00
334_L	503_L	2.334	1.00
261_N	393_W	2.308	1.00
30_S	33_I	2.252	1.00
440_L	476_H	2.245	1.00
444_V	475_I	2.191	1.00
279_M	283_A	2.174	1.00
279_M	282_L	2.146	1.00
429_R	432_N	2.146	1.00
431_L	445_V	2.086	1.00
302_T	398_S	2.050	1.00
40_I	44_P	2.032	1.00
434_L	445_V	2.027	1.00
138_M	141_S	2.000	1.00
150_L	154_T	1.996	1.00
104_D	114_H	1.942	1.00
368_R	371_S	1.920	1.00
264_L	394_F	1.919	1.00
151_V	155_W	1.917	1.00
212_M	216_R	1.912	1.00
244_V	247_P	1.878	1.00
213_T	217_F	1.858	1.00
380_I	437_S	1.844	1.00
54_Y	58_I	1.808	1.00
198_P	201_M	1.806	1.00
214_A	217_F	1.789	1.00
168_R	171_R	1.778	1.00
378_Q	381_N	1.751	1.00
265_I	427_I	1.742	1.00
146_L	150_L	1.719	1.00
142_V	145_I	1.690	1.00
168_R	172_P	1.688	1.00
277_K	280_P	1.686	1.00
216_R	219_E	1.678	1.00
376_A	399_F	1.668	1.00
364_M	367_V	1.662	1.00
30_S	34_G	1.659	1.00
266_T	306_I	1.657	1.00
409_Q	414_R	1.637	1.00
213_T	219_E	1.635	1.00
473_L	494_L	1.622	1.00
179_I	183_A	1.621	1.00
32_V	40_I	1.619	1.00
440_L	445_V	1.619	1.00
382_W	385_R	1.615	1.00
403_N	450_G	1.612	1.00
354_Y	358_L	1.606	1.00
27_I	31_L	1.599	1.00
264_L	446_I	1.576	1.00
446_I	475_I	1.576	1.00
393_W	439_K	1.570	1.00
353_L	356_Q	1.554	1.00
497_T	519_F	1.549	1.00
295_H	473_L	1.547	1.00
448_T	491_H	1.543	1.00
343_L	398_S	1.543	1.00
312_G	496_T	1.537	1.00
333_A	499_M	1.536	1.00
379_W	397_V	1.534	1.00
455_L	458_E	1.533	1.00
212_M	220_K	1.527	1.00
293_T	484_R	1.521	1.00
453_I	456_S	1.519	1.00
463_D	467_G	1.514	1.00
213_T	220_K	1.511	1.00
425_D	429_R	1.496	1.00
267_V	423_V	1.496	1.00
373_E	422_N	1.492	1.00
214_A	218_L	1.492	1.00
376_A	380_I	1.491	1.00
311_Y	329_A	1.487	1.00
245_Q	248_L	1.486	1.00
449_A	471_V	1.475	1.00
317_Y	320_G	1.474	1.00
402_T	420_A	1.473	1.00
270_L	423_V	1.465	1.00
373_E	429_R	1.455	1.00
430_V	445_V	1.454	1.00
433_A	437_S	1.449	1.00
270_L	274_R	1.446	1.00
284_G	428_N	1.437	1.00
402_T	419_A	1.425	1.00
36_R	40_I	1.417	1.00
285_F	427_I	1.412	1.00
35_S	40_I	1.404	1.00
330_L	498_L	1.399	1.00
289_N	476_H	1.395	1.00
50_R	54_Y	1.386	1.00
309_L	448_T	1.384	1.00
342_G	395_S	1.376	1.00
272_Y	470_Q	1.374	1.00
40_I	43_W	1.369	1.00
212_M	219_E	1.354	1.00
280_P	283_A	1.337	1.00
29_L	33_I	1.337	1.00
258_T	442_N	1.334	1.00
274_R	420_A	1.329	1.00
281_A	431_L	1.327	1.00
139_F	142_V	1.323	1.00
33_I	36_R	1.321	1.00
448_T	494_L	1.318	1.00
267_V	427_I	1.318	1.00
212_M	217_F	1.317	1.00
34_G	40_I	1.317	1.00
212_M	218_L	1.316	1.00
267_V	447_I	1.307	1.00
477_W	480_T	1.304	1.00
421_G	425_D	1.294	1.00
380_I	384_G	1.293	1.00
318_M	321_I	1.292	1.00
354_Y	357_A	1.285	1.00
365_P	368_R	1.282	1.00
352_P	358_L	1.281	1.00
284_G	288_Q	1.280	1.00
376_A	430_V	1.280	1.00
138_M	142_V	1.277	1.00
271_N	452_G	1.275	1.00
31_L	34_G	1.271	1.00
201_M	207_P	1.266	1.00
215_R	219_E	1.266	1.00
260_Q	444_V	1.261	1.00
379_W	383_L	1.256	1.00
290_I	519_F	1.256	1.00
352_P	357_A	1.255	1.00
52_Y	56_S	1.248	1.00
30_S	37_Y	1.245	1.00
36_R	39_F	1.230	1.00
344_F	382_W	1.223	1.00
280_P	424_D	1.222	1.00
453_I	459_E	1.218	1.00
433_A	436_D	1.216	1.00
444_V	498_L	1.210	1.00
375_T	397_V	1.207	1.00
372_D	376_A	1.207	1.00
244_V	248_L	1.204	1.00
34_G	39_F	1.203	1.00
230_Q	233_L	1.200	1.00
426_Q	429_R	1.184	1.00
50_R	57_I	1.184	1.00
216_R	220_K	1.182	1.00
499_M	505_V	1.179	1.00
170_A	174_A	1.178	1.00
296_M	470_Q	1.172	1.00
463_D	466_H	1.171	1.00
431_L	435_R	1.171	1.00
270_L	420_A	1.169	1.00
367_V	370_Q	1.162	1.00
266_T	448_T	1.159	1.00
53_S	56_S	1.153	1.00
285_F	431_L	1.148	1.00
266_T	309_L	1.144	1.00
281_A	432_N	1.140	1.00
180_A	183_A	1.136	1.00
290_I	485_I	1.135	1.00
282_L	427_I	1.133	1.00
454_P	457_E	1.131	1.00
39_F	42_D	1.129	1.00
192_D	196_Y	1.128	1.00
446_I	498_L	1.127	1.00
364_M	368_R	1.123	1.00
302_T	403_N	1.118	1.00
444_V	477_W	1.111	1.00
27_I	33_I	1.110	1.00
221_H	229_Y	1.104	1.00
66_F	70_L	1.102	1.00
153_A	157_W	1.101	1.00
384_G	433_A	1.101	1.00
377_T	429_R	1.098	1.00
146_L	149_E	1.097	1.00
339_Y	392_R	1.096	1.00
298_S	490_D	1.093	1.00
292_F	473_L	1.093	1.00
43_W	47_L	1.090	1.00
142_V	148_L	1.089	1.00
337_Q	505_V	1.087	1.00
30_S	39_F	1.074	0.99
30_S	36_R	1.067	0.99
134_D	137_L	1.063	0.99
343_L	358_L	1.062	0.99
34_G	38_L	1.061	0.99
309_L	494_L	1.060	0.99
268_D	450_G	1.059	0.99
344_F	395_S	1.057	0.99
53_S	58_I	1.057	0.99
139_F	145_I	1.056	0.99
32_V	36_R	1.051	0.99
270_L	279_M	1.051	0.99
52_Y	57_I	1.048	0.99
199_I	204_A	1.047	0.99
154_T	158_Q	1.046	0.99
33_I	40_I	1.044	0.99
212_M	215_R	1.042	0.99
425_D	428_N	1.040	0.99
285_F	474_V	1.040	0.99
264_L	309_L	1.039	0.99
294_R	470_Q	1.037	0.99
363_S	367_V	1.036	0.99
246_Y	249_S	1.034	0.99
175_A	178_F	1.033	0.99
46_T	50_R	1.032	0.99
208_L	211_P	1.023	0.99
453_I	461_T	1.022	0.99
429_R	433_A	1.021	0.99
229_Y	233_L	1.014	0.99
190_W	195_F	1.010	0.99
286_A	291_S	1.009	0.99
63_F	66_F	1.009	0.99
208_L	212_M	1.008	0.99
294_R	488_L	1.007	0.99
198_P	202_Q	1.006	0.99
441_D	479_G	1.005	0.99
496_T	515_G	1.002	0.99
317_Y	321_I	1.002	0.99
202_Q	206_L	1.000	0.99
266_T	396_W	0.996	0.99
59_G	63_F	0.995	0.99
145_I	148_L	0.994	0.99
185_H	192_D	0.992	0.99
262_V	444_V	0.988	0.99
49_G	54_Y	0.988	0.99
206_L	209_S	0.986	0.99
253_Y	519_F	0.983	0.99
60_H	63_F	0.981	0.99
154_T	157_W	0.980	0.99
57_I	60_H	0.979	0.99
247_P	251_L	0.978	0.99
262_V	446_I	0.976	0.99
141_S	145_I	0.975	0.99
276_E	279_M	0.974	0.99
363_S	368_R	0.972	0.99
170_A	173_L	0.970	0.99
221_H	225_D	0.965	0.99
139_F	148_L	0.965	0.99
227_Q	230_Q	0.962	0.99
36_R	43_W	0.961	0.99
298_S	308_G	0.959	0.99
517_D	520_N	0.957	0.99
362_F	368_R	0.955	0.99
177_L	181_F	0.954	0.99
378_Q	382_W	0.949	0.99
383_L	395_S	0.949	0.99
230_Q	235_E	0.947	0.99
27_I	36_R	0.946	0.99
351_S	355_R	0.946	0.99
320_G	323_S	0.946	0.99
334_L	499_M	0.945	0.99
453_I	457_E	0.944	0.99
31_L	35_S	0.944	0.99
185_H	189_I	0.942	0.99
41_A	45_T	0.932	0.99
167_R	170_A	0.932	0.99
350_T	355_R	0.931	0.99
262_V	394_F	0.930	0.99
215_R	218_L	0.930	0.99
402_T	423_V	0.926	0.98
350_T	354_Y	0.926	0.98
265_I	376_A	0.925	0.98
226_A	229_Y	0.924	0.98
27_I	34_G	0.924	0.98
381_N	385_R	0.922	0.98
176_F	180_A	0.920	0.98
263_L	393_W	0.919	0.98
214_A	219_E	0.919	0.98
290_I	483_Q	0.918	0.98
214_A	220_K	0.915	0.98
49_G	53_S	0.914	0.98
431_L	447_I	0.910	0.98
274_R	417_S	0.908	0.98
284_G	287_E	0.907	0.98
407_S	415_K	0.906	0.98
261_N	441_D	0.906	0.98
243_S	247_P	0.903	0.98
272_Y	291_S	0.903	0.98
319_D	323_S	0.903	0.98
454_P	459_E	0.902	0.98
150_L	158_Q	0.902	0.98
55_V	58_I	0.901	0.98
455_L	459_E	0.899	0.98
471_V	491_H	0.899	0.98
353_L	357_A	0.893	0.98
68_T	72_I	0.890	0.98
167_R	171_R	0.890	0.98
276_E	280_P	0.888	0.98
222_G	227_Q	0.888	0.98
46_T	49_G	0.887	0.98
264_L	494_L	0.887	0.98
172_P	175_A	0.885	0.98
352_P	355_R	0.880	0.98
310_F	394_F	0.877	0.98
349_F	355_R	0.877	0.98
137_L	141_S	0.870	0.98
30_S	38_L	0.868	0.98
454_P	458_E	0.866	0.98
41_A	44_P	0.865	0.98
213_T	218_L	0.865	0.98
351_S	358_L	0.864	0.98
70_L	73_L	0.862	0.98
247_P	250_E	0.862	0.98
373_E	425_D	0.860	0.98
201_M	204_A	0.858	0.97
224_L	229_Y	0.856	0.97
353_L	358_L	0.855	0.97
149_E	153_A	0.852	0.97
209_S	212_M	0.852	0.97
434_L	439_K	0.850	0.97
278_Q	421_G	0.849	0.97
271_N	416_Y	0.849	0.97
342_G	393_W	0.848	0.97
205_N	208_L	0.848	0.97
367_V	371_S	0.847	0.97
423_V	426_Q	0.846	0.97
401_G	419_A	0.844	0.97
221_H	224_L	0.844	0.97
221_H	233_L	0.844	0.97
361_D	365_P	0.842	0.97
286_A	474_V	0.841	0.97
190_W	196_Y	0.841	0.97
200_T	203_R	0.835	0.97
261_N	442_N	0.831	0.97
28_L	38_L	0.831	0.97
149_E	157_W	0.830	0.97
268_D	403_N	0.829	0.97
179_I	182_I	0.827	0.97
352_P	356_Q	0.825	0.97
285_F	447_I	0.825	0.97
224_L	233_L	0.824	0.97
333_A	336_Q	0.824	0.97
34_G	44_P	0.823	0.97
456_S	459_E	0.822	0.97
361_D	368_R	0.820	0.97
291_S	484_R	0.820	0.97
58_I	63_F	0.819	0.97
46_T	53_S	0.819	0.97
308_G	491_H	0.819	0.97
50_R	53_S	0.817	0.97
374_Q	377_T	0.817	0.97
207_P	211_P	0.813	0.97
403_N	451_R	0.812	0.96
259_G	337_Q	0.811	0.96
210_Y	214_A	0.810	0.96
447_I	474_V	0.810	0.96
281_A	425_D	0.805	0.96
302_T	450_G	0.805	0.96
264_L	330_L	0.805	0.96
282_L	474_V	0.803	0.96
495_M	499_M	0.803	0.96
56_S	60_H	0.802	0.96
270_L	275_F	0.802	0.96
427_I	447_I	0.802	0.96
172_P	183_A	0.796	0.96
330_L	495_M	0.794	0.96
139_F	143_P	0.794	0.96
361_D	367_V	0.793	0.96
342_G	382_W	0.792	0.96
453_I	458_E	0.791	0.96
28_L	36_R	0.791	0.96
319_D	322_L	0.790	0.96
207_P	212_M	0.789	0.96
197_R	203_R	0.789	0.96
104_D	115_L	0.786	0.96
172_P	180_A	0.784	0.96
27_I	39_F	0.783	0.96
222_G	226_A	0.782	0.96
230_Q	234_I	0.782	0.96
169_F	172_P	0.780	0.96
36_R	42_D	0.780	0.96
200_T	208_L	0.780	0.96
172_P	176_F	0.780	0.96
30_S	40_I	0.779	0.96
379_W	395_S	0.779	0.96
228_E	233_L	0.778	0.96
431_L	440_L	0.777	0.95
280_P	285_F	0.776	0.95
35_S	42_D	0.776	0.95
140_I	144_V	0.774	0.95
268_D	399_F	0.774	0.95
261_N	392_R	0.772	0.95
362_F	367_V	0.771	0.95
414_R	418_R	0.771	0.95
334_L	394_F	0.768	0.95
189_I	193_A	0.766	0.95
95_T	99_T	0.766	0.95
197_R	201_M	0.766	0.95
349_F	364_M	0.762	0.95
359_L	362_F	0.762	0.95
36_R	44_P	0.757	0.95
362_F	365_P	0.757	0.95
28_L	39_F	0.755	0.95
172_P	179_I	0.755	0.95
71_L	75_P	0.754	0.95
201_M	209_S	0.753	0.95
263_L	383_L	0.753	0.95
270_L	447_I	0.753	0.95
209_S	214_A	0.752	0.95
59_G	62_S	0.750	0.95
197_R	200_T	0.748	0.94
382_W	386_Y	0.744	0.94
171_R	182_I	0.743	0.94
422_N	425_D	0.742	0.94
457_E	461_T	0.738	0.94
27_I	40_I	0.737	0.94
62_S	65_V	0.737	0.94
229_Y	234_I	0.736	0.94
227_Q	231_R	0.733	0.94
345_S	354_Y	0.732	0.94
243_S	246_Y	0.727	0.94
142_V	150_L	0.725	0.93
377_T	433_A	0.724	0.93
441_D	478_P	0.722	0.93
36_R	41_A	0.721	0.93
266_T	398_S	0.721	0.93
434_L	438_G	0.720	0.93
493_D	515_G	0.718	0.93
201_M	205_N	0.716	0.93
376_A	423_V	0.716	0.93
201_M	210_Y	0.715	0.93
44_P	47_L	0.713	0.93
374_Q	378_Q	0.713	0.93
175_A	179_I	0.712	0.93
150_L	157_W	0.711	0.93
307_F	321_I	0.711	0.93
91_V	94_A	0.711	0.93
147_L	151_V	0.711	0.93
260_Q	339_Y	0.710	0.93
341_L	394_F	0.710	0.93
399_F	423_V	0.710	0.93
199_I	211_P	0.706	0.93
311_Y	357_A	0.705	0.93
171_R	177_L	0.705	0.93
38_L	44_P	0.705	0.93
335_N	341_L	0.704	0.92
427_I	445_V	0.702	0.92
34_G	43_W	0.700	0.92
40_I	46_T	0.700	0.92
45_T	49_G	0.697	0.92
137_L	148_L	0.692	0.92
316_S	321_I	0.690	0.92
321_I	324_T	0.689	0.92
340_Q	498_L	0.686	0.91
62_S	72_I	0.686	0.91
361_D	371_S	0.686	0.91
61_F	64_L	0.685	0.91
267_V	376_A	0.685	0.91
338_G	392_R	0.684	0.91
195_F	203_R	0.683	0.91
188_Y	191_A	0.683	0.91
189_I	192_D	0.683	0.91
33_I	41_A	0.682	0.91
297_S	452_G	0.681	0.91
500_Q	520_N	0.678	0.91
157_W	160_L	0.678	0.91
275_F	279_M	0.675	0.91
411_A	415_K	0.674	0.91
29_L	39_F	0.674	0.91
88_F	92_I	0.672	0.91
107_V	116_N	0.670	0.91
243_S	248_L	0.670	0.91
281_A	424_D	0.670	0.91
416_Y	420_A	0.670	0.91
103_I	115_L	0.670	0.91
65_V	69_Y	0.669	0.90
453_I	460_E	0.668	0.90
428_N	431_L	0.668	0.90
77_T	80_V	0.667	0.90
454_P	461_T	0.665	0.90
46_T	54_Y	0.665	0.90
223_L	230_Q	0.665	0.90
328_A	336_Q	0.665	0.90
426_Q	430_V	0.663	0.90
104_D	402_T	0.661	0.90
119_V	122_L	0.661	0.90
27_I	42_D	0.660	0.90
351_S	356_Q	0.660	0.90
32_V	35_S	0.659	0.90
250_E	253_Y	0.658	0.90
286_A	293_T	0.657	0.90
223_L	231_R	0.656	0.90
315_P	318_M	0.655	0.90
90_S	93_L	0.655	0.90
242_V	245_Q	0.655	0.90
447_I	476_H	0.654	0.89
198_P	207_P	0.652	0.89
29_L	36_R	0.651	0.89
264_L	396_W	0.651	0.89
423_V	491_H	0.650	0.89
115_L	275_F	0.648	0.89
291_S	474_V	0.648	0.89
231_R	234_I	0.647	0.89
186_V	189_I	0.647	0.89
347_D	400_N	0.647	0.89
29_L	34_G	0.646	0.89
316_S	319_D	0.644	0.89
235_E	239_P	0.642	0.89
130_E	133_R	0.642	0.89
58_I	62_S	0.642	0.89
32_V	39_F	0.642	0.89
270_L	282_L	0.640	0.88
39_F	43_W	0.640	0.88
64_L	68_T	0.640	0.88
199_I	208_L	0.639	0.88
303_D	352_P	0.637	0.88
302_T	306_I	0.635	0.88
196_Y	201_M	0.634	0.88
137_L	145_I	0.633	0.88
156_S	159_K	0.632	0.88
342_G	386_Y	0.630	0.88
268_D	402_T	0.630	0.88
185_H	190_W	0.628	0.87
427_I	431_L	0.628	0.87
133_R	136_Q	0.628	0.87
417_S	421_G	0.627	0.87
67_A	70_L	0.627	0.87
126_P	130_E	0.626	0.87
144_V	148_L	0.626	0.87
346_S	400_N	0.624	0.87
423_V	427_I	0.623	0.87
27_I	41_A	0.621	0.87
198_P	204_A	0.621	0.87
133_R	137_L	0.621	0.87
33_I	39_F	0.619	0.87
226_A	231_R	0.619	0.87
228_E	231_R	0.618	0.87
515_G	518_L	0.617	0.87
146_L	158_Q	0.615	0.86
171_R	174_A	0.614	0.86
52_Y	55_V	0.614	0.86
171_R	175_A	0.614	0.86
141_S	149_E	0.613	0.86
31_L	39_F	0.613	0.86
413_A	416_Y	0.613	0.86
302_T	451_R	0.612	0.86
454_P	468_H	0.612	0.86
150_L	153_A	0.612	0.86
211_P	215_R	0.611	0.86
224_L	227_Q	0.611	0.86
138_M	148_L	0.611	0.86
89_L	93_L	0.610	0.86
166_R	172_P	0.610	0.86
27_I	43_W	0.609	0.86
188_Y	196_Y	0.608	0.86
286_A	289_N	0.607	0.86
260_Q	392_R	0.606	0.86
340_Q	389_E	0.606	0.86
226_A	233_L	0.605	0.85
408_N	418_R	0.604	0.85
268_D	372_D	0.603	0.85
107_V	304_N	0.601	0.85
283_A	286_A	0.601	0.85
270_L	402_T	0.599	0.85
331_I	341_L	0.599	0.85
27_I	38_L	0.599	0.85
401_G	422_N	0.598	0.85
42_D	46_T	0.598	0.85
193_A	196_Y	0.597	0.85
281_A	285_F	0.597	0.85
177_L	180_A	0.596	0.85
211_P	220_K	0.596	0.85
191_A	196_Y	0.595	0.85
306_I	354_Y	0.595	0.85
364_M	371_S	0.594	0.84
354_Y	448_T	0.593	0.84
122_L	125_N	0.592	0.84
38_L	42_D	0.591	0.84
255_D	259_G	0.591	0.84
73_L	76_L	0.590	0.84
126_P	131_M	0.589	0.84
223_L	226_A	0.589	0.84
345_S	352_P	0.587	0.84
475_I	497_T	0.587	0.84
282_L	420_A	0.587	0.84
329_A	494_L	0.586	0.84
231_R	235_E	0.582	0.83
39_F	44_P	0.581	0.83
61_F	66_F	0.579	0.83
32_V	44_P	0.578	0.83
40_I	45_T	0.577	0.83
222_G	225_D	0.577	0.83
409_Q	412_F	0.576	0.83
331_I	394_F	0.575	0.82
217_F	220_K	0.575	0.82
29_L	32_V	0.573	0.82
391_N	442_N	0.572	0.82
29_L	40_I	0.572	0.82
284_G	435_R	0.572	0.82
293_T	485_I	0.570	0.82
275_F	282_L	0.570	0.82
314_S	514_Q	0.569	0.82
264_L	448_T	0.568	0.82
188_Y	192_D	0.568	0.82
334_L	337_Q	0.566	0.82
31_L	38_L	0.565	0.81
472_P	475_I	0.565	0.81
310_F	396_W	0.564	0.81
175_A	182_I	0.563	0.81
186_V	192_D	0.563	0.81
42_D	45_T	0.562	0.81
229_Y	235_E	0.561	0.81
259_G	392_R	0.561	0.81
69_Y	73_L	0.560	0.81
261_N	444_V	0.559	0.81
30_S	35_S	0.559	0.81
37_Y	40_I	0.558	0.81
59_G	77_T	0.558	0.81
444_V	480_T	0.558	0.81
263_L	434_L	0.557	0.80
137_L	144_V	0.557	0.80
156_S	160_L	0.556	0.80
135_W	139_F	0.556	0.80
495_M	513_S	0.554	0.80
185_H	188_Y	0.554	0.80
171_R	178_F	0.553	0.80
269_G	449_A	0.553	0.80
209_S	213_T	0.552	0.80
33_I	44_P	0.552	0.80
339_Y	503_L	0.552	0.80
509_A	513_S	0.552	0.80
224_L	228_E	0.551	0.80
162_S	167_R	0.550	0.80
305_G	471_V	0.550	0.80
241_A	245_Q	0.550	0.80
222_G	229_Y	0.549	0.80
66_F	74_F	0.549	0.80
330_L	499_M	0.549	0.80
188_Y	193_A	0.548	0.79
155_W	159_K	0.548	0.79
347_D	406_D	0.547	0.79
473_L	489_T	0.546	0.79
383_L	434_L	0.544	0.79
365_P	371_S	0.544	0.79
316_S	320_G	0.543	0.79
66_F	73_L	0.541	0.79
306_I	345_S	0.540	0.78
251_L	254_R	0.539	0.78
129_N	132_A	0.539	0.78
210_Y	219_E	0.538	0.78
187_V	191_A	0.538	0.78
68_T	75_P	0.538	0.78
170_A	181_F	0.538	0.78
225_D	229_Y	0.537	0.78
180_A	188_Y	0.537	0.78
442_N	446_I	0.536	0.78
65_V	68_T	0.536	0.78
54_Y	59_G	0.536	0.78
292_F	296_M	0.535	0.78
287_E	484_R	0.534	0.78
308_G	399_F	0.531	0.77
145_I	149_E	0.531	0.77
195_F	199_I	0.529	0.77
95_T	157_W	0.529	0.77
215_R	220_K	0.528	0.77
232_R	235_E	0.528	0.77
62_S	73_L	0.528	0.77
58_I	61_F	0.527	0.77
200_T	204_A	0.527	0.77
457_E	460_E	0.526	0.77
305_G	491_H	0.526	0.77
398_S	449_A	0.526	0.77
28_L	32_V	0.525	0.76
277_K	283_A	0.524	0.76
53_S	59_G	0.523	0.76
194_N	198_P	0.523	0.76
83_Q	87_R	0.523	0.76
51_I	58_I	0.522	0.76
345_S	400_N	0.521	0.76
409_Q	415_K	0.521	0.76
107_V	275_F	0.521	0.76
316_S	324_T	0.521	0.76
289_N	474_V	0.520	0.76
37_Y	43_W	0.519	0.76
182_I	185_H	0.518	0.76
33_I	37_Y	0.516	0.75
108_F	115_L	0.516	0.75
172_P	182_I	0.516	0.75
149_E	158_Q	0.516	0.75
199_I	207_P	0.515	0.75
200_T	210_Y	0.514	0.75
200_T	206_L	0.514	0.75
297_S	471_V	0.514	0.75
201_M	206_L	0.514	0.75
185_H	193_A	0.512	0.75
153_A	156_S	0.511	0.75
32_V	37_Y	0.510	0.74
121_Q	125_N	0.509	0.74
49_G	52_Y	0.508	0.74
223_L	234_I	0.508	0.74
37_Y	41_A	0.508	0.74
399_F	430_V	0.507	0.74
417_S	449_A	0.507	0.74
359_L	396_W	0.506	0.74
202_Q	205_N	0.506	0.74
201_M	208_L	0.505	0.74
245_Q	249_S	0.505	0.74
410_Q	414_R	0.504	0.74
206_L	210_Y	0.503	0.73
473_L	518_L	0.502	0.73
111_F	116_N	0.502	0.73
267_V	402_T	0.502	0.73
204_A	207_P	0.501	0.73
381_N	384_G	0.500	0.73

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4upiA	2	0.5529	100	0.484	Contact Map
4uplA	2	0.5529	100	0.486	Contact Map
3lxqA	1	0.6041	100	0.488	Contact Map
2vqrA	3	0.5495	100	0.488	Contact Map
3b5qA	1	0.5529	100	0.489	Contact Map
4uphA	2	0.5478	100	0.489	Contact Map
4upkA	3	0.5495	100	0.494	Contact Map
1aukA	3	0.5563	100	0.495	Contact Map
1fsuA	1	0.5546	100	0.499	Contact Map
4uopA	2	0.5939	100	0.5	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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