GREMLIN Database
YEJL - UPF0352 protein YejL
UniProt: P0AD24 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12043
Length: 75 (71)
Sequences: 165 (77)
Seq/√Len: 9.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
58_A62_A3.5100.96
15_L19_L2.7640.87
3_Q6_R2.7120.86
18_E25_K2.1760.70
16_L42_T2.0740.66
11_Q26_H1.9080.59
43_N53_Q1.7890.54
20_L30_T1.7830.54
18_E43_N1.7780.54
33_S41_V1.7720.54
30_T47_T1.7680.53
8_S49_I1.6760.49
29_P69_I1.6670.49
15_L29_P1.5610.44
57_I67_S1.4830.41
15_L27_K1.4500.40
41_V58_A1.4460.39
8_S13_E1.4460.39
53_Q60_S1.4290.39
44_L47_T1.3860.37
16_L57_I1.3040.34
27_K52_A1.2940.33
42_T68_S1.2870.33
31_D51_P1.2620.32
16_L40_M1.2450.31
28_A33_S1.2380.31
18_E57_I1.2070.30
3_Q8_S1.1220.27
18_E24_E1.1080.27
15_L50_A1.1070.26
23_L33_S1.0970.26
12_V64_A1.0970.26
13_E64_A1.0890.26
40_M57_I1.0830.26
11_Q27_K1.0420.24
11_Q28_A1.0420.24
9_D53_Q1.0410.24
46_N64_A1.0220.24
2_P29_P1.0150.23
44_L48_S1.0090.23
48_S53_Q1.0080.23
4_I37_L1.0040.23
31_D37_L0.9830.22
17_A47_T0.9750.22
2_P60_S0.9470.21
43_N48_S0.9360.21
30_T44_L0.8910.20
15_L36_V0.8800.19
59_N63_R0.8770.19
2_P11_Q0.8540.19
37_L40_M0.8450.19
63_R66_Q0.8260.18
26_H70_N0.8250.18
10_E42_T0.8180.18
56_A69_I0.8080.18
59_N66_Q0.8050.17
18_E26_H0.7890.17
8_S69_I0.7830.17
6_R50_A0.7660.17
15_L52_A0.7650.17
10_E46_N0.7540.16
3_Q9_D0.7410.16
9_D59_N0.7340.16
11_Q55_Q0.7330.16
14_Q26_H0.7200.15
19_L36_V0.7110.15
2_P69_I0.7050.15
9_D31_D0.6960.15
57_I62_A0.6960.15
14_Q33_S0.6910.15
14_Q71_E0.6780.15
16_L22_V0.6690.14
29_P44_L0.6660.14
19_L40_M0.6650.14
45_I66_Q0.6630.14
29_P37_L0.6540.14
51_P63_R0.6540.14
23_L32_L0.6520.14
55_Q59_N0.6380.14
30_T64_A0.6380.14
3_Q57_I0.6360.14
58_A66_Q0.6230.13
15_L37_L0.6080.13
16_L50_A0.6060.13
20_L42_T0.5910.13
18_E67_S0.5910.13
14_Q17_A0.5900.13
63_R70_N0.5880.13
22_V45_I0.5810.13
58_A61_F0.5790.12
13_E30_T0.5730.12
20_L24_E0.5700.12
2_P48_S0.5680.12
12_V70_N0.5670.12
55_Q71_E0.5660.12
27_K44_L0.5620.12
19_L29_P0.5470.12
40_M48_S0.5310.12
26_H29_P0.5270.12
46_N53_Q0.5260.12
13_E35_M0.5170.11
25_K59_N0.5140.11
9_D66_Q0.5070.11
33_S70_N0.5020.11
13_E23_L0.5010.11
50_A55_Q0.5000.11
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2jpqA 2 1 100 0.005 Contact Map
2jrxA 2 1 100 0.006 Contact Map
2juzA 2 1 100 0.033 Contact Map
2juwA 2 1 100 0.033 Contact Map
2jr2A 2 0.9867 100 0.063 Contact Map
3t5sA 3 0.92 32.9 0.903 Contact Map
3c6vA 3 1 27.1 0.907 Contact Map
3fwtA 3 0.9867 20.3 0.912 Contact Map
3bb8A 2 0.36 19.8 0.913 Contact Map
3fwuA 3 0.9733 18.5 0.914 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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