GREMLIN Database
YECA - Uncharacterized protein YecA
UniProt: P0AD05 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11139
Length: 221 (191)
Sequences: 551 (418)
Seq/√Len: 30.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
13_W74_R7.5441.00
42_S121_Y5.4211.00
10_E81_Q4.1931.00
39_A124_G3.9191.00
49_P80_F3.3011.00
52_W83_M3.1481.00
34_D82_H3.1051.00
121_Y175_A3.0631.00
6_L81_Q3.0121.00
17_I75_F2.5050.99
47_I51_Q2.4290.99
35_G120_G2.4000.99
84_A87_A2.3120.99
38_T97_F2.2600.99
28_L32_E2.2140.99
36_L124_G2.1370.98
43_S182_W2.1250.98
6_L10_E2.0910.98
57_W64_P2.0580.98
6_L78_L1.9680.97
196_K199_E1.9550.97
73_T77_N1.8710.96
140_A143_A1.8420.95
36_L55_A1.8190.95
37_L127_L1.8110.95
194_P197_A1.7870.94
122_M125_V1.7730.94
88_E166_E1.6550.92
43_S181_Y1.6070.91
24_D32_E1.6070.91
114_V147_H1.5930.90
160_S163_A1.5810.90
10_E74_R1.5620.89
31_A114_V1.5400.89
122_M141_L1.5310.88
75_F144_I1.5050.87
17_I20_K1.4810.87
55_A58_G1.4500.85
20_K24_D1.4310.85
43_S178_L1.3960.83
31_A34_D1.3560.81
33_L57_W1.3100.79
15_D30_V1.2980.78
195_I198_E1.2730.77
69_E76_M1.2640.76
130_W147_H1.2560.76
90_L141_L1.2510.76
41_L87_A1.2450.75
195_I199_E1.2400.75
179_H183_M1.2280.74
33_L120_G1.2240.74
38_T99_P1.2050.73
67_A71_E1.1940.72
12_E111_L1.1790.71
167_S171_I1.1780.71
7_N10_E1.1770.71
43_S124_G1.1760.71
43_S130_W1.1530.69
36_L156_V1.1440.69
66_W147_H1.1430.69
15_D19_T1.1380.68
68_S94_P1.1340.68
118_C121_Y1.1310.68
183_M186_P1.1250.67
49_P53_L1.1180.67
52_W56_V1.1170.67
36_L40_V1.1120.67
197_A200_K1.0920.65
46_E50_E1.0800.64
57_W148_G1.0770.64
20_K23_T1.0770.64
75_F108_G1.0720.64
101_F171_I1.0710.64
193_Q200_K1.0700.64
82_H85_D1.0680.63
26_A37_L1.0660.63
21_Y121_Y1.0660.63
39_A118_C1.0660.63
42_S179_H1.0610.63
130_W172_R1.0520.62
51_Q110_E1.0490.62
174_A181_Y1.0480.62
70_K73_T1.0390.61
80_F105_E1.0390.61
80_F84_A1.0380.61
36_L57_W1.0330.61
74_R78_L1.0330.61
8_E50_E1.0300.61
51_Q80_F1.0250.60
115_E171_I1.0230.60
152_N156_V1.0120.59
33_L66_W1.0020.58
128_S132_T0.9980.58
80_F136_S0.9940.58
101_F112_T0.9910.57
34_D100_L0.9760.56
60_A73_T0.9650.55
94_P132_T0.9520.54
191_V194_P0.9480.54
46_E73_T0.9480.54
16_D104_R0.9460.54
179_H182_W0.9320.53
38_T57_W0.9310.53
57_W171_I0.9310.53
35_G121_Y0.9220.52
190_A194_P0.9160.52
49_P84_A0.9150.51
33_L72_M0.9120.51
43_S179_H0.9100.51
50_E80_F0.9060.51
20_K25_H0.9050.51
22_N47_I0.9030.51
36_L92_E0.9020.50
33_L79_A0.8870.49
69_E73_T0.8850.49
194_P200_K0.8820.49
69_E72_M0.8810.49
192_Q197_A0.8790.49
40_V87_A0.8790.49
31_A182_W0.8770.48
30_V56_V0.8740.48
64_P69_E0.8700.48
24_D31_A0.8640.47
109_S159_M0.8640.47
139_P149_T0.8620.47
87_A90_L0.8570.47
21_Y24_D0.8550.47
42_S90_L0.8480.46
48_E141_L0.8370.45
39_A147_H0.8350.45
178_L182_W0.8210.44
43_S143_A0.8170.44
118_C174_A0.8150.44
39_A130_W0.8140.43
82_H99_P0.8140.43
54_V161_P0.8060.43
93_F96_Q0.7990.42
21_Y124_G0.7900.42
81_Q86_T0.7890.42
39_A43_S0.7860.41
68_S100_L0.7830.41
75_F130_W0.7800.41
42_S112_T0.7770.41
161_P170_A0.7750.40
193_Q196_K0.7690.40
45_Q191_V0.7680.40
37_L79_A0.7670.40
44_P188_E0.7630.40
48_E80_F0.7620.39
178_L181_Y0.7610.39
10_E13_W0.7600.39
78_L81_Q0.7590.39
122_M179_H0.7560.39
139_P142_E0.7550.39
149_T152_N0.7430.38
95_E178_L0.7420.38
38_T86_T0.7340.37
117_W124_G0.7250.37
21_Y26_A0.7240.37
92_E162_E0.7220.36
60_A107_D0.7200.36
13_W78_L0.7200.36
53_L154_E0.7180.36
161_P175_A0.7160.36
18_L158_K0.7160.36
118_C122_M0.7150.36
114_V164_F0.7100.36
111_L165_E0.7030.35
120_G184_A0.7020.35
15_D159_M0.7000.35
90_L190_A0.6970.35
117_W143_A0.6960.35
72_M76_M0.6930.34
107_D111_L0.6890.34
49_P86_T0.6870.34
60_A141_L0.6870.34
8_E23_T0.6840.34
78_L99_P0.6840.34
39_A83_M0.6810.33
50_E72_M0.6800.33
37_L150_E0.6750.33
103_L110_E0.6730.33
21_Y42_S0.6730.33
75_F91_N0.6700.33
72_M80_F0.6680.33
193_Q199_E0.6660.32
30_V52_W0.6650.32
34_D99_P0.6620.32
46_E56_V0.6620.32
67_A107_D0.6580.32
51_Q175_A0.6570.32
64_P71_E0.6530.32
38_T66_W0.6510.31
191_V199_E0.6470.31
79_A189_K0.6470.31
79_A160_S0.6470.31
65_R73_T0.6470.31
51_Q132_T0.6460.31
34_D120_G0.6410.31
76_M84_A0.6390.31
31_A147_H0.6350.30
190_A199_E0.6350.30
93_F171_I0.6320.30
193_Q197_A0.6300.30
21_Y123_R0.6290.30
38_T41_L0.6270.30
89_R94_P0.6260.30
83_M173_L0.6250.30
44_P117_W0.6220.29
147_H172_R0.6210.29
10_E58_G0.6180.29
15_D92_E0.6180.29
35_G52_W0.6160.29
57_W94_P0.6150.29
23_T30_V0.6130.29
143_A158_K0.6130.29
79_A165_E0.6110.29
97_F118_C0.6060.28
101_F200_K0.6050.28
47_I87_A0.6050.28
32_E178_L0.6040.28
143_A149_T0.6030.28
47_I50_E0.6020.28
60_A76_M0.6020.28
16_D98_E0.6000.28
113_I149_T0.5980.28
177_D181_Y0.5960.28
89_R102_G0.5950.28
38_T120_G0.5930.28
166_E188_E0.5920.27
124_G182_W0.5880.27
26_A29_D0.5880.27
15_D95_E0.5870.27
6_L125_V0.5870.27
37_L64_P0.5860.27
11_L53_L0.5830.27
99_P131_S0.5810.27
175_A183_M0.5780.27
36_L196_K0.5750.26
37_L40_V0.5700.26
98_E118_C0.5700.26
116_E120_G0.5690.26
40_V46_E0.5670.26
114_V118_C0.5640.26
11_L149_T0.5590.25
30_V172_R0.5580.25
100_L105_E0.5560.25
60_A109_S0.5550.25
17_I21_Y0.5530.25
56_V72_M0.5530.25
9_S129_D0.5510.25
32_E55_A0.5500.25
42_S175_A0.5450.25
116_E195_I0.5420.24
21_Y71_E0.5420.24
78_L85_D0.5400.24
50_E85_D0.5400.24
33_L165_E0.5370.24
13_W121_Y0.5350.24
96_Q118_C0.5350.24
136_S159_M0.5320.24
31_A126_A0.5270.24
6_L97_F0.5240.23
58_G113_I0.5230.23
136_S144_I0.5220.23
51_Q155_R0.5220.23
69_E144_I0.5200.23
36_L109_S0.5190.23
150_E157_E0.5190.23
17_I132_T0.5150.23
195_I200_K0.5150.23
70_K139_P0.5140.23
41_L156_V0.5140.23
99_P133_L0.5120.23
9_S67_A0.5120.23
41_L118_C0.5090.23
192_Q199_E0.5080.22
173_L180_A0.5070.22
57_W101_F0.5070.22
170_A177_D0.5060.22
94_P100_L0.5050.22
109_S157_E0.5030.22
18_L32_E0.5030.22
155_R173_L0.5030.22
68_S140_A0.5010.22
139_P183_M0.5000.22
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4gytA 2 0.7738 100 0.616 Contact Map
1izmA 2 0.7511 100 0.624 Contact Map
1tf5A 1 0.724 99.7 0.742 Contact Map
2i9wA 1 0.6516 99.5 0.783 Contact Map
2ipcA 2 0.7285 99.1 0.819 Contact Map
1ozbI 1 0.095 98.9 0.837 Contact Map
1l5jA 1 0.9186 60.1 0.944 Contact Map
4i6pA 2 0.1312 18.8 0.958 Contact Map
1wveC 1 0.1086 14.9 0.96 Contact Map
4qoxA 1 0.6923 10.6 0.963 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0073 seconds.