GREMLIN Database
YDGC - Inner membrane protein YdgC
UniProt: P0ACX0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13191
Length: 111 (109)
Sequences: 112 (62)
Seq/√Len: 5.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
63_M70_F2.9830.77
66_I70_F2.6550.68
47_A85_L2.5470.64
47_A51_G2.4590.61
22_K78_Y2.4270.60
32_I80_T2.1990.53
51_G54_A2.1160.50
57_A102_V2.0030.46
26_Y59_I1.9400.43
19_V22_K1.8510.40
88_A104_I1.8500.40
2_G104_I1.8490.40
91_G104_I1.8170.39
71_V95_C1.8140.39
5_I18_G1.7530.37
47_A77_W1.6780.35
59_I76_L1.6560.34
13_V18_G1.6330.33
19_V70_F1.5910.32
94_A99_S1.5550.31
81_G86_P1.5110.30
26_Y65_S1.4770.29
28_I65_S1.4350.27
26_Y104_I1.4240.27
67_I71_V1.4220.27
98_I102_V1.3980.26
48_S110_L1.3640.25
76_L84_R1.3510.25
48_S97_G1.3470.25
47_A54_A1.3440.25
64_W104_I1.3010.24
64_W99_S1.2770.23
17_I56_R1.2260.22
26_Y84_R1.2190.22
8_A110_L1.1900.21
24_K65_S1.1880.21
8_A23_T1.1880.21
26_Y76_L1.1780.21
4_V15_L1.1780.21
59_I80_T1.1690.21
60_I63_M1.1630.20
59_I66_I1.1610.20
71_V99_S1.1510.20
83_M94_A1.1470.20
87_A91_G1.1460.20
9_L82_M1.1370.20
79_F99_S1.1300.20
30_G42_A1.1250.20
52_I84_R1.1240.20
8_A85_L1.0930.19
99_S110_L1.0920.19
95_C110_L1.0900.19
56_R81_G1.0840.19
60_I70_F1.0780.19
62_S69_Y1.0780.19
44_Y86_P1.0680.18
7_A26_Y1.0660.18
26_Y88_A1.0650.18
63_M93_V1.0440.18
11_A45_I1.0410.18
80_T88_A1.0360.18
18_G49_E1.0180.17
24_K28_I1.0050.17
9_L37_T1.0000.17
59_I88_A0.9970.17
47_A50_R0.9870.17
26_Y52_I0.9830.17
66_I76_L0.9800.17
13_V32_I0.9740.16
57_A108_I0.9680.16
44_Y77_W0.9600.16
59_I70_F0.9570.16
50_R54_A0.9520.16
63_M74_V0.9480.16
64_W71_V0.9440.16
15_L74_V0.9400.16
76_L93_V0.9300.16
5_I99_S0.9130.15
12_L22_K0.9110.15
44_Y50_R0.9090.15
52_I80_T0.9090.15
22_K53_E0.9040.15
2_G27_Y0.9010.15
24_K53_E0.8990.15
63_M84_R0.8810.15
8_A24_K0.8800.15
23_T105_I0.8800.15
64_W95_C0.8680.14
12_L78_Y0.8640.14
101_W109_K0.8640.14
59_I84_R0.8570.14
52_I88_A0.8550.14
45_I53_E0.8220.14
5_I94_A0.8040.13
87_A90_V0.8010.13
8_A51_G0.7900.13
4_V26_Y0.7580.13
24_K91_G0.7530.13
101_W108_I0.7420.12
71_V78_Y0.7410.12
53_E67_I0.7410.12
51_G106_C0.7390.12
27_Y71_V0.7370.12
7_A21_A0.7320.12
18_G25_N0.7260.12
44_Y75_S0.7230.12
5_I45_I0.7140.12
99_S108_I0.7140.12
9_L51_G0.7040.12
50_R85_L0.7010.12
82_M110_L0.6920.12
54_A74_V0.6910.12
19_V108_I0.6690.11
52_I81_G0.6670.11
44_Y80_T0.6640.11
75_S95_C0.6580.11
8_A102_V0.6550.11
25_N85_L0.6550.11
70_F76_L0.6540.11
60_I77_W0.6540.11
71_V87_A0.6510.11
54_A97_G0.6500.11
9_L93_V0.6480.11
5_I90_V0.6480.11
95_C99_S0.6430.11
105_I109_K0.6320.11
5_I105_I0.6270.11
2_G46_V0.6260.11
28_I79_F0.6250.11
76_L88_A0.6200.11
82_M94_A0.6180.11
7_A65_S0.6140.11
64_W75_S0.6110.11
4_V32_I0.6100.11
94_A106_C0.6100.11
17_I107_W0.6090.10
99_S104_I0.6000.10
82_M102_V0.5950.10
12_L86_P0.5900.10
53_E97_G0.5890.10
16_L24_K0.5880.10
16_L92_S0.5860.10
8_A94_A0.5780.10
49_E85_L0.5780.10
78_Y99_S0.5720.10
22_K74_V0.5630.10
19_V90_V0.5630.10
5_I12_L0.5600.10
8_A77_W0.5600.10
12_L98_I0.5570.10
82_M93_V0.5450.10
2_G66_I0.5440.10
24_K85_L0.5290.09
62_S74_V0.5230.09
11_A37_T0.5220.09
57_A94_A0.5200.09
29_A99_S0.5180.09
2_G101_W0.5180.09
48_S109_K0.5140.09
25_N109_K0.5100.09
91_G98_I0.5100.09
19_V49_E0.5080.09
59_I93_V0.5020.09
3_L30_G0.5000.09
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2gfpA 2 0.8108 1.7 0.965 Contact Map
2qvwA 3 0.3333 1.2 0.968 Contact Map
2ls3A 1 0.2613 1.1 0.969 Contact Map
4j72A 2 0.6847 0.9 0.971 Contact Map
4cctA 7 0.3694 0.9 0.971 Contact Map
2lzqA 1 0.1261 0.9 0.971 Contact Map
3j27A 7 0.3694 0.8 0.971 Contact Map
4cbfA 7 0.3694 0.8 0.971 Contact Map
2k3cA 1 0.2793 0.8 0.972 Contact Map
4humA 1 0.973 0.8 0.972 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0056 seconds.