GREMLIN Database
MBHM - Hydrogenase-2 large chain
UniProt: P0ACE0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11801
Length: 567 (545)
Sequences: 565 (324)
Seq/√Len: 13.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
262_T429_T7.5291.00
308_D311_S5.6981.00
183_V186_I5.0841.00
130_A186_I4.5961.00
53_A493_I4.5441.00
395_Q399_N4.5431.00
489_K494_S4.5401.00
155_I158_L4.1731.00
285_V483_S4.1181.00
200_D249_K3.7320.99
337_K352_A3.6450.99
468_E489_K3.6410.99
102_H106_V3.6180.99
506_S518_Y3.4700.99
121_S184_N3.4700.99
279_A517_P3.4690.99
7_I28_V3.4490.99
101_T254_V3.4050.99
326_G371_Y3.3620.99
45_V53_A3.3540.99
118_D173_G3.2680.98
529_D532_K3.2480.98
373_K514_D3.2040.98
152_Q156_K3.1880.98
502_S547_M3.1280.98
387_L399_N3.0490.98
45_V57_V2.9940.97
112_S425_I2.9920.97
255_E433_C2.9820.97
156_K160_A2.9570.97
244_K248_D2.9140.97
113_A117_V2.9060.97
113_A187_A2.8800.96
458_F462_N2.8300.96
133_M183_V2.8150.96
462_N466_T2.8030.96
255_E437_D2.7630.95
149_T153_N2.7480.95
386_K394_T2.7010.95
94_I439_L2.6960.95
45_V493_I2.6440.94
367_S507_G2.6160.94
444_S448_T2.5910.94
117_V187_A2.5780.93
133_M186_I2.5350.93
118_D184_N2.5310.93
463_I466_T2.4770.92
187_A265_I2.4540.92
365_V547_M2.3680.90
460_K463_I2.3560.90
30_K515_V2.2870.88
390_G395_Q2.2740.88
248_D440_Q2.2570.88
414_E417_Q2.2080.86
93_N289_P2.1670.85
357_S360_G2.1310.84
303_Y375_V2.1240.84
60_I498_A2.1110.84
369_T507_G2.0620.82
87_N449_N2.0500.82
95_I208_L2.0430.82
6_T20_D2.0380.81
97_A288_F2.0350.81
382_N431_H2.0250.81
458_F463_I2.0100.81
391_R394_T1.9930.80
337_K350_I1.9920.80
415_V418_L1.9560.79
22_E32_W1.9470.78
273_L422_L1.9450.78
275_R525_T1.9250.77
200_D203_R1.9240.77
387_L398_L1.9000.77
304_I384_L1.8650.75
342_Q347_G1.8300.74
266_A327_I1.8170.73
251_S437_D1.8160.73
346_E470_K1.7880.72
421_T539_T1.7820.72
99_H106_V1.7780.71
470_K487_V1.7750.71
369_T510_N1.7430.70
560_E563_S1.7410.70
510_N514_D1.7130.69
277_K282_Y1.7070.68
326_G370_F1.7030.68
306_N373_K1.7000.68
75_A486_M1.6870.67
76_A220_V1.6680.66
118_D121_S1.6480.65
285_V481_M1.6480.65
154_K158_L1.6450.65
19_I33_A1.6220.64
22_E30_K1.6150.64
38_W351_P1.6120.64
314_P389_A1.6110.64
448_T452_K1.6090.63
173_G184_N1.6050.63
119_I173_G1.5740.62
128_T145_P1.5580.61
202_N212_T1.5510.61
266_A422_L1.5390.60
460_K466_T1.5160.59
100_T435_L1.5040.58
57_V493_I1.5010.58
251_S255_E1.4970.58
227_I450_I1.4730.56
342_Q348_T1.4710.56
228_N231_G1.4690.56
458_F461_P1.4680.56
280_V307_A1.4670.56
113_A258_Y1.4630.56
183_V268_F1.4630.56
284_S385_V1.4460.55
420_S539_T1.4440.55
387_L395_Q1.4310.54
183_V264_V1.4310.54
35_G547_M1.4300.54
518_Y550_A1.4280.54
105_I197_C1.4230.54
392_E396_N1.4220.54
240_L447_I1.4150.53
129_K132_E1.4100.53
309_L388_A1.4010.53
553_V561_V1.3980.52
208_L243_I1.3960.52
135_K143_N1.3950.52
401_I430_V1.3890.52
7_I536_V1.3830.52
338_D361_K1.3700.51
396_N400_E1.3690.51
247_I439_L1.3660.51
330_S341_P1.3620.50
244_K444_S1.3590.50
228_N232_L1.3520.50
228_N242_Y1.3460.50
204_V439_L1.3400.49
323_L326_G1.3290.49
402_V417_Q1.3190.48
487_V494_S1.3000.47
201_A250_L1.2990.47
133_M268_F1.2970.47
120_T124_Q1.2910.47
47_N53_A1.2860.46
155_I188_V1.2850.46
506_S550_A1.2830.46
345_W507_G1.2800.46
207_L242_Y1.2770.46
75_A183_V1.2680.45
149_T152_Q1.2660.45
128_T132_E1.2630.45
537_V541_H1.2630.45
443_Y447_I1.2610.45
394_T523_V1.2580.45
78_S472_V1.2460.44
312_Y385_V1.2360.44
266_A270_P1.2330.44
97_A442_Q1.2280.43
244_K443_Y1.2240.43
252_D256_Q1.2220.43
86_V445_A1.2160.43
180_P268_F1.2150.43
30_K523_V1.2120.42
130_A148_F1.2040.42
208_L225_N1.2040.42
560_E565_K1.1990.42
123_L159_V1.1970.42
180_P264_V1.1970.42
303_Y315_I1.1850.41
265_I275_R1.1810.41
72_S473_G1.1810.41
224_A243_I1.1800.41
498_A516_G1.1790.41
97_A439_L1.1770.41
387_L390_G1.1640.40
28_V316_T1.1640.40
393_S441_N1.1620.40
153_N157_D1.1500.39
58_Q66_T1.1480.39
507_G510_N1.1460.39
186_I264_V1.1430.39
193_Q196_E1.1390.39
357_S452_K1.1370.39
369_T374_T1.1320.38
67_T99_H1.1280.38
120_T159_V1.1200.38
286_P431_H1.1190.38
35_G550_A1.1160.37
112_S177_M1.1140.37
328_Q341_P1.1120.37
252_D486_M1.1110.37
334_S363_S1.1080.37
10_V502_S1.1080.37
298_L516_G1.1040.37
399_N403_A1.1020.37
6_T36_T1.0990.37
279_A520_Q1.0970.36
110_Q194_A1.0910.36
151_V192_L1.0870.36
413_L417_Q1.0840.36
283_L375_V1.0830.36
247_I443_Y1.0810.36
398_L418_L1.0800.36
141_H256_Q1.0790.36
244_K447_I1.0740.35
282_Y384_L1.0690.35
283_L377_V1.0680.35
180_P183_V1.0650.35
369_T514_D1.0640.35
400_E410_G1.0630.35
38_W43_E1.0630.35
78_S322_Y1.0540.34
419_H426_I1.0530.34
431_H476_E1.0520.34
502_S506_S1.0480.34
309_L419_H1.0440.34
153_N156_K1.0420.34
72_S351_P1.0370.34
129_K133_M1.0360.33
58_Q69_A1.0350.33
67_T96_L1.0320.33
101_T439_L1.0290.33
43_E46_K1.0230.33
136_G140_W1.0220.33
243_I247_I1.0210.33
5_I23_I1.0120.32
549_C552_H1.0110.32
459_V462_N1.0110.32
322_Y370_F1.0100.32
147_E205_V1.0080.32
414_E430_V1.0040.32
139_T256_Q1.0020.32
324_I472_V1.0010.32
397_K437_D0.9970.32
304_I309_L0.9960.32
91_I547_M0.9950.32
67_T475_L0.9940.31
146_E210_G0.9930.31
97_A101_T0.9920.31
338_D350_I0.9900.31
327_I486_M0.9890.31
117_V179_L0.9870.31
166_I367_S0.9860.31
244_K440_Q0.9830.31
401_I426_I0.9820.31
486_M496_Y0.9680.30
393_S438_I0.9640.30
393_S437_D0.9600.30
398_L402_V0.9580.30
131_S145_P0.9570.30
28_V105_I0.9550.30
170_G327_I0.9540.30
135_K146_E0.9520.30
96_L218_L0.9500.29
448_T451_G0.9500.29
69_A74_R0.9460.29
24_E29_S0.9420.29
10_V308_D0.9420.29
353_Y499_V0.9350.29
356_W376_E0.9320.29
53_A521_S0.9310.29
365_V498_A0.9300.29
130_A264_V0.9270.28
305_E373_K0.9230.28
390_G401_I0.9220.28
131_S144_S0.9210.28
545_P549_C0.9200.28
546_C549_C0.9200.28
259_K429_T0.9190.28
146_E150_K0.9180.28
180_P411_N0.9180.28
174_H528_A0.9160.28
174_H272_W0.9150.28
53_A57_V0.9120.28
299_F323_L0.9120.28
91_I248_D0.9120.28
324_I345_W0.9080.28
453_G539_T0.9080.28
70_L74_R0.9040.27
96_L475_L0.9040.27
441_N445_A0.9030.27
397_K433_C0.8980.27
148_F212_T0.8960.27
10_V19_I0.8940.27
376_E481_M0.8930.27
81_N84_V0.8910.27
69_A361_K0.8900.27
124_Q152_Q0.8890.27
158_L454_D0.8890.27
282_Y419_H0.8880.27
105_I250_L0.8860.27
204_V224_A0.8850.27
518_Y534_L0.8850.27
146_E326_G0.8840.27
544_D549_C0.8820.27
298_L442_Q0.8810.26
140_W143_N0.8800.26
558_G561_V0.8780.26
239_R242_Y0.8720.26
89_Q286_P0.8720.26
4_R358_D0.8700.26
9_P12_R0.8670.26
131_S143_N0.8650.26
135_K144_S0.8620.26
217_N228_N0.8620.26
328_Q331_A0.8610.26
147_E193_Q0.8590.26
305_E313_R0.8580.26
263_A410_G0.8540.25
304_I427_G0.8520.25
280_V376_E0.8470.25
343_A417_Q0.8460.25
515_V520_Q0.8460.25
134_L137_V0.8450.25
498_A534_L0.8450.25
434_E438_I0.8450.25
308_D388_A0.8440.25
127_P152_Q0.8430.25
43_E58_Q0.8430.25
281_N388_A0.8420.25
194_A253_F0.8410.25
120_T160_A0.8410.25
205_V212_T0.8400.25
438_I441_N0.8400.25
461_P466_T0.8390.25
330_S511_F0.8380.25
99_H502_S0.8360.25
207_L246_F0.8350.25
60_I457_T0.8320.24
138_S257_V0.8310.24
433_C437_D0.8260.24
71_S374_T0.8260.24
288_F442_Q0.8190.24
35_G365_V0.8190.24
343_A347_G0.8190.24
383_M394_T0.8170.24
26_G527_V0.8170.24
67_T102_H0.8160.24
119_I137_V0.8120.24
259_K372_G0.8110.24
75_A293_K0.8090.24
65_T103_D0.8080.24
376_E525_T0.8060.23
6_T215_I0.8050.23
71_S531_N0.8050.23
202_N223_V0.8040.23
125_A185_L0.8040.23
340_A395_Q0.8030.23
350_I394_T0.8000.23
39_R42_E0.7990.23
456_T561_V0.7970.23
468_E487_V0.7970.23
32_W551_V0.7970.23
131_S451_G0.7960.23
199_R506_S0.7950.23
223_V495_N0.7950.23
59_R64_C0.7940.23
277_K280_V0.7930.23
41_M553_V0.7920.23
264_V268_F0.7920.23
93_N442_Q0.7910.23
82_I483_S0.7900.23
154_K392_E0.7900.23
142_L516_G0.7900.23
439_L442_Q0.7890.23
250_L439_L0.7860.23
46_K494_S0.7850.23
270_P412_T0.7840.23
300_P327_I0.7840.23
284_S382_N0.7840.23
200_D246_F0.7820.23
36_T51_R0.7810.22
45_V327_I0.7800.22
26_G557_D0.7780.22
418_L422_L0.7780.22
315_I481_M0.7770.22
95_I217_N0.7740.22
300_P386_K0.7730.22
334_S367_S0.7700.22
133_M454_D0.7670.22
102_H367_S0.7640.22
277_K307_A0.7620.22
120_T188_V0.7620.22
219_A432_C0.7610.22
54_W217_N0.7610.22
36_T355_G0.7590.22
240_L443_Y0.7570.22
199_R498_A0.7560.22
258_Y495_N0.7550.22
41_M57_V0.7550.22
382_N476_E0.7540.21
202_N205_V0.7530.21
498_A518_Y0.7510.21
461_P477_A0.7510.21
342_Q489_K0.7510.21
346_E487_V0.7510.21
100_T288_F0.7500.21
313_R412_T0.7490.21
203_R273_L0.7490.21
418_L490_D0.7490.21
458_F466_T0.7480.21
246_F249_K0.7470.21
86_V89_Q0.7470.21
128_T350_I0.7440.21
430_V452_K0.7430.21
17_L550_A0.7420.21
415_V457_T0.7400.21
129_K182_E0.7390.21
141_H239_R0.7390.21
60_I518_Y0.7390.21
276_G521_S0.7380.21
223_V457_T0.7370.21
272_W275_R0.7350.21
118_D169_N0.7330.21
506_S534_L0.7310.21
101_T334_S0.7300.21
502_S507_G0.7300.21
545_P552_H0.7300.21
546_C552_H0.7300.21
74_R473_G0.7290.21
23_I26_G0.7280.21
338_D341_P0.7280.21
142_L152_Q0.7270.21
278_G292_S0.7260.20
182_E335_W0.7250.20
325_K371_Y0.7250.20
351_P364_W0.7240.20
304_I520_Q0.7230.20
70_L210_G0.7230.20
177_M425_I0.7210.20
450_I455_H0.7200.20
309_L417_Q0.7190.20
156_K374_T0.7180.20
150_K153_N0.7170.20
283_L481_M0.7170.20
300_P481_M0.7170.20
210_G476_E0.7150.20
202_N219_A0.7140.20
54_W66_T0.7140.20
467_G490_D0.7130.20
416_A563_S0.7110.20
330_S451_G0.7070.20
134_L141_H0.7070.20
328_Q483_S0.7050.20
199_R558_G0.7050.20
37_M564_V0.7040.20
417_Q422_L0.7020.20
158_L426_I0.7020.20
86_V474_F0.7010.20
392_E527_V0.7010.20
229_L298_L0.7010.20
224_A526_P0.7000.20
434_E502_S0.6990.20
284_S476_E0.6990.20
70_L473_G0.6990.20
187_A264_V0.6980.20
397_K401_I0.6980.20
29_S531_N0.6980.20
94_I153_N0.6970.19
197_C201_A0.6970.19
308_D353_Y0.6950.19
499_V510_N0.6950.19
169_N525_T0.6950.19
118_D529_D0.6940.19
7_I548_A0.6920.19
544_D552_H0.6920.19
372_G512_N0.6920.19
281_N375_V0.6900.19
135_K148_F0.6890.19
78_S81_N0.6880.19
461_P464_P0.6870.19
87_N364_W0.6870.19
468_E494_S0.6870.19
110_Q270_P0.6860.19
146_E328_Q0.6860.19
402_V427_G0.6860.19
508_P548_A0.6810.19
277_K358_D0.6810.19
278_G445_A0.6810.19
52_D162_G0.6810.19
28_V32_W0.6800.19
494_S553_V0.6790.19
84_V256_Q0.6790.19
202_N206_A0.6790.19
204_V247_I0.6780.19
174_H535_E0.6760.19
554_V561_V0.6760.19
8_D18_R0.6740.19
376_E508_P0.6730.19
299_F381_A0.6710.19
33_A502_S0.6710.19
290_T441_N0.6700.19
396_N403_A0.6690.19
460_K490_D0.6680.19
38_W551_V0.6680.19
177_M431_H0.6680.19
128_T359_D0.6660.18
251_S440_Q0.6650.18
377_V500_V0.6640.18
47_N113_A0.6640.18
133_M137_V0.6620.18
19_I551_V0.6620.18
331_A340_A0.6620.18
60_I516_G0.6600.18
240_L371_Y0.6600.18
446_L449_N0.6600.18
454_D487_V0.6590.18
438_I442_Q0.6580.18
171_Y253_F0.6570.18
71_S96_L0.6560.18
198_Q541_H0.6560.18
272_W384_L0.6550.18
140_W224_A0.6540.18
525_T539_T0.6540.18
392_E395_Q0.6530.18
4_R7_I0.6530.18
299_F434_E0.6530.18
47_N493_I0.6490.18
81_N450_I0.6490.18
69_A204_V0.6490.18
152_Q328_Q0.6490.18
125_A541_H0.6470.18
245_S248_D0.6470.18
16_H63_V0.6450.18
120_T525_T0.6450.18
515_V523_V0.6450.18
40_G61_C0.6430.18
403_A412_T0.6430.18
345_W426_I0.6420.18
99_H286_P0.6390.18
5_I174_H0.6380.18
47_N73_V0.6380.18
106_V361_K0.6380.18
23_I29_S0.6380.18
119_I338_D0.6370.18
339_E515_V0.6370.18
502_S518_Y0.6360.17
71_S263_A0.6360.17
6_T301_G0.6340.17
97_A239_R0.6330.17
374_T517_P0.6330.17
122_A185_L0.6310.17
140_W144_S0.6310.17
294_N297_F0.6310.17
247_I440_Q0.6310.17
263_A411_N0.6300.17
6_T119_I0.6290.17
314_P323_L0.6290.17
305_E312_Y0.6280.17
435_L551_V0.6270.17
101_T250_L0.6270.17
80_L116_W0.6260.17
38_W187_A0.6240.17
128_T339_E0.6230.17
290_T296_S0.6220.17
118_D253_F0.6210.17
19_I524_G0.6200.17
18_R209_G0.6200.17
390_G402_V0.6200.17
153_N374_T0.6200.17
94_I105_I0.6180.17
152_Q160_A0.6180.17
417_Q426_I0.6180.17
195_L198_Q0.6180.17
151_V447_I0.6180.17
24_E266_A0.6170.17
42_E61_C0.6170.17
39_R61_C0.6170.17
67_T72_S0.6170.17
219_A303_Y0.6160.17
88_A122_A0.6160.17
220_V308_D0.6150.17
25_N489_K0.6140.17
271_E427_G0.6140.17
77_E80_L0.6140.17
310_S498_A0.6130.17
90_Y445_A0.6130.17
88_A125_A0.6110.17
19_I540_I0.6110.17
551_V555_D0.6110.17
345_W536_V0.6100.17
210_G231_G0.6100.17
77_E564_V0.6100.17
554_V558_G0.6090.17
383_M398_L0.6090.17
46_K489_K0.6080.17
286_P301_G0.6080.17
36_T547_M0.6070.17
81_N491_G0.6060.17
253_F257_V0.6060.17
41_M521_S0.6060.17
112_S258_Y0.6060.17
337_K346_E0.6050.17
325_K328_Q0.6050.17
225_N250_L0.6030.16
38_W95_I0.6020.16
467_G491_G0.6010.16
286_P469_F0.6010.16
94_I98_A0.6010.16
35_G551_V0.6010.16
40_G62_G0.5990.16
140_W193_Q0.5990.16
288_F439_L0.5980.16
268_F417_Q0.5970.16
90_Y332_K0.5970.16
255_E308_D0.5950.16
105_I434_E0.5950.16
19_I502_S0.5950.16
70_L218_L0.5940.16
303_Y373_K0.5930.16
22_E551_V0.5920.16
411_N521_S0.5910.16
165_G169_N0.5900.16
332_K513_D0.5890.16
154_K219_A0.5890.16
251_S439_L0.5890.16
149_T512_N0.5880.16
208_L451_G0.5870.16
182_E198_Q0.5860.16
283_L476_E0.5860.16
166_I170_G0.5860.16
298_L526_P0.5860.16
388_A392_E0.5850.16
260_V331_A0.5840.16
293_K310_S0.5840.16
54_W76_A0.5830.16
349_T497_Q0.5820.16
91_I454_D0.5810.16
518_Y540_I0.5810.16
203_R241_M0.5810.16
155_I458_F0.5800.16
119_I159_V0.5790.16
119_I184_N0.5770.16
100_T477_A0.5760.16
334_S348_T0.5760.16
39_R62_G0.5750.16
42_E62_G0.5750.16
172_W496_Y0.5750.16
247_I457_T0.5750.16
44_I65_T0.5740.16
470_K561_V0.5740.16
28_V416_A0.5740.16
54_W227_I0.5730.16
208_L224_A0.5730.16
226_P231_G0.5720.16
87_N446_L0.5720.16
94_I381_A0.5720.16
554_V560_E0.5700.16
334_S392_E0.5690.15
120_T403_A0.5690.15
118_D522_L0.5690.15
88_A91_I0.5680.15
54_W69_A0.5680.15
122_A125_A0.5680.15
129_K370_F0.5680.15
284_S536_V0.5670.15
284_S554_V0.5660.15
301_G389_A0.5660.15
339_E511_F0.5660.15
10_V34_S0.5660.15
10_V403_A0.5660.15
6_T356_W0.5660.15
217_N443_Y0.5660.15
475_L498_A0.5650.15
140_W256_Q0.5640.15
282_Y517_P0.5640.15
30_K509_R0.5630.15
332_K377_V0.5620.15
255_E400_E0.5610.15
139_T531_N0.5600.15
212_T387_L0.5600.15
300_P477_A0.5590.15
90_Y242_Y0.5590.15
506_S555_D0.5580.15
118_D141_H0.5580.15
219_A458_F0.5580.15
255_E327_I0.5580.15
74_R287_E0.5570.15
390_G399_N0.5570.15
75_A133_M0.5560.15
250_L525_T0.5560.15
179_L260_V0.5560.15
416_A524_G0.5560.15
343_A478_P0.5560.15
373_K512_N0.5550.15
299_F307_A0.5550.15
94_I426_I0.5540.15
95_I330_S0.5530.15
154_K458_F0.5520.15
93_N477_A0.5510.15
507_G547_M0.5510.15
12_R16_H0.5510.15
9_P16_H0.5510.15
206_A248_D0.5500.15
402_V430_V0.5500.15
156_K161_S0.5500.15
217_N243_I0.5490.15
61_C64_C0.5490.15
9_P13_I0.5480.15
249_K448_T0.5480.15
283_L486_M0.5480.15
298_L457_T0.5470.15
205_V286_P0.5470.15
89_Q370_F0.5470.15
377_V530_P0.5460.15
485_W500_V0.5460.15
246_F271_E0.5460.15
37_M73_V0.5460.15
8_D16_H0.5450.15
84_V297_F0.5450.15
262_T521_S0.5450.15
340_A347_G0.5450.15
89_Q445_A0.5440.15
502_S514_D0.5440.15
82_I151_V0.5440.15
255_E397_K0.5430.15
57_V169_N0.5430.15
331_A347_G0.5430.15
121_S534_L0.5420.15
207_L437_D0.5410.15
83_D489_K0.5400.15
42_E59_R0.5400.15
39_R64_C0.5400.15
42_E64_C0.5400.15
39_R59_R0.5400.15
113_A264_V0.5390.15
76_A488_I0.5390.15
12_R61_C0.5380.15
9_P61_C0.5380.15
155_I537_V0.5380.15
21_C166_I0.5380.15
130_A147_E0.5380.15
113_A265_I0.5370.15
21_C30_K0.5360.15
169_N173_G0.5350.15
395_Q512_N0.5350.15
8_D20_D0.5340.15
194_A496_Y0.5340.15
160_A304_I0.5330.15
113_A390_G0.5330.15
66_T210_G0.5320.14
3_Q30_K0.5310.14
128_T135_K0.5310.14
231_G239_R0.5310.14
117_V390_G0.5300.14
73_V553_V0.5300.14
46_K490_D0.5300.14
376_E419_H0.5290.14
118_D206_A0.5290.14
154_K456_T0.5260.14
140_W230_D0.5260.14
248_D251_S0.5250.14
171_Y281_N0.5250.14
418_L427_G0.5250.14
558_G564_V0.5240.14
99_H215_I0.5240.14
293_K304_I0.5240.14
128_T328_Q0.5220.14
12_R39_R0.5220.14
12_R42_E0.5220.14
9_P42_E0.5220.14
9_P39_R0.5220.14
217_N539_T0.5220.14
185_L423_G0.5220.14
73_V163_Q0.5210.14
70_L161_S0.5200.14
38_W469_F0.5200.14
3_Q78_S0.5200.14
163_Q537_V0.5200.14
157_D502_S0.5200.14
28_V460_K0.5190.14
60_I491_G0.5190.14
176_A526_P0.5180.14
166_I356_W0.5180.14
262_T315_I0.5180.14
369_T513_D0.5170.14
80_L343_A0.5160.14
95_I224_A0.5150.14
505_N508_P0.5150.14
102_H163_Q0.5140.14
97_A438_I0.5130.14
278_G307_A0.5130.14
119_I532_K0.5110.14
246_F298_L0.5110.14
145_P157_D0.5100.14
58_Q254_V0.5100.14
47_N57_V0.5100.14
136_G139_T0.5090.14
84_V491_G0.5080.14
358_D445_A0.5080.14
243_I443_Y0.5080.14
271_E420_S0.5070.14
229_L512_N0.5070.14
59_R62_G0.5070.14
91_I247_I0.5070.14
182_E192_L0.5060.14
110_Q432_C0.5050.14
415_V489_K0.5050.14
3_Q561_V0.5040.14
306_N493_I0.5040.14
217_N240_L0.5040.14
55_M219_A0.5040.14
52_D169_N0.5040.14
53_A67_T0.5030.14
164_L425_I0.5030.14
259_K427_G0.5030.14
383_M434_E0.5020.14
208_L443_Y0.5020.14
331_A509_R0.5020.14
285_V365_V0.5020.14
429_T437_D0.5010.14
166_I183_V0.5010.14
469_F481_M0.5010.14
421_T541_H0.5010.14
60_I554_V0.5010.14
26_G41_M0.5010.14
382_N481_M0.5000.14
148_F257_V0.5000.14
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ayxA 2 0.9489 100 0.319 Contact Map
3myrB 2 0.9506 100 0.36 Contact Map
4u9hL 1 0.933 100 0.374 Contact Map
4ue3L 2 0.9506 100 0.375 Contact Map
4uqlQ 1 0.933 100 0.375 Contact Map
4c3oA 2 0.9506 100 0.376 Contact Map
1e3dB 1 0.9295 100 0.382 Contact Map
1yq9H 1 0.9295 100 0.389 Contact Map
4kn9L 2 0.8395 100 0.51 Contact Map
3ze9B 1 0.8413 100 0.524 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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