GREMLIN Database
MBHL - Hydrogenase-1 large chain
UniProt: P0ACD8 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10469
Length: 597 (548)
Sequences: 571 (311)
Seq/√Len: 13.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
279_A456_A7.9551.00
198_A201_M5.4431.00
68_A523_I4.7901.00
145_T201_M4.6871.00
428_V432_D4.6581.00
519_R524_D4.6301.00
170_L173_F4.5691.00
304_Y513_G4.3841.00
355_R373_W3.8670.99
117_H121_V3.7960.99
21_V43_I3.7790.99
536_A548_Y3.7200.99
60_L68_A3.7030.99
136_D199_N3.6980.99
420_Y432_D3.6660.99
133_D188_G3.5370.99
344_Q404_R3.4490.99
116_C271_I3.4260.99
215_E266_R3.3890.99
559_I562_Q3.3420.98
272_N460_Q3.3020.98
167_Q171_K3.2670.98
498_E519_R3.2320.98
60_L72_V3.2240.98
406_N544_Q3.2020.98
296_L547_A3.1220.98
127_A452_I3.1190.98
128_G132_I3.1050.97
261_Q265_T3.0950.97
419_A427_T3.0540.97
128_G202_G3.0160.97
171_K175_E2.9880.97
148_L198_A2.9250.96
471_D475_T2.8990.96
272_N464_G2.8390.96
60_L523_I2.8360.96
164_F168_N2.8060.95
532_T577_L2.7140.94
133_D199_N2.7050.94
148_L201_M2.6660.94
132_I202_G2.6370.93
202_G282_I2.6320.93
400_A537_S2.6210.93
109_I466_L2.6190.93
45_N545_I2.4030.90
398_I577_L2.4000.90
420_Y431_V2.3130.88
112_A307_F2.2120.85
441_P444_G2.2040.85
75_I528_C2.1870.84
326_V417_L2.1410.83
390_N393_E2.1370.83
265_T467_Q2.1090.82
402_R537_S2.0890.82
20_V34_E2.0840.81
325_A408_M2.0560.81
328_N406_N2.0420.80
415_R458_E2.0040.79
110_M223_F2.0020.79
108_N308_P2.0000.79
363_R368_G1.9980.79
215_E218_K1.9720.78
355_R371_D1.9490.77
102_N476_N1.9140.75
114_L121_V1.9010.75
36_N47_V1.8950.75
448_T569_T1.8900.74
540_D544_Q1.8700.74
133_D136_D1.8670.73
283_G345_V1.8500.73
424_D427_T1.8400.72
134_V188_G1.8300.72
402_R540_D1.7960.70
268_A464_G1.7790.70
304_Y511_A1.7750.70
292_I555_T1.7720.69
188_G199_N1.7660.69
169_R173_F1.7600.69
290_S449_L1.7550.69
590_E593_S1.7500.68
283_G449_L1.7480.68
143_R160_P1.7330.68
268_A272_N1.6920.66
367_D500_R1.6780.65
36_N45_N1.6600.64
500_R517_A1.6550.64
344_Q403_W1.6510.64
53_F372_P1.6430.63
90_A516_A1.6200.62
120_L212_F1.5950.61
217_V227_N1.5860.60
363_R369_I1.5630.59
144_K147_E1.5620.59
331_F421_H1.5560.59
475_T479_N1.5550.59
241_I477_L1.5440.58
62_G68_A1.5420.58
442_L445_I1.5400.58
359_D362_G1.5370.58
33_C48_S1.5330.58
490_W495_W1.5150.57
359_D394_R1.4910.56
295_G573_F1.4910.56
423_G428_V1.4800.55
366_F537_S1.4710.55
548_Y580_S1.4660.54
115_W462_A1.4640.54
50_G577_L1.4590.54
303_S418_I1.4570.54
198_A281_A1.4440.53
434_M453_L1.4420.53
261_Q470_F1.4420.53
425_A429_E1.4200.52
128_G275_M1.4190.52
433_R437_A1.4000.51
93_D502_V1.3970.51
341_D344_Q1.3900.50
429_E433_R1.3850.50
166_V207_L1.3840.50
420_Y428_V1.3790.50
264_I466_L1.3770.50
198_A285_F1.3770.50
470_F474_M1.3760.50
330_D421_H1.3760.50
340_V403_W1.3750.49
261_Q474_M1.3630.49
90_A198_A1.3540.48
261_Q471_D1.3510.48
135_L139_K1.3510.48
283_G287_K1.3430.48
242_N259_L1.3390.48
143_R147_E1.3370.47
430_S464_G1.3370.47
447_S569_T1.3340.47
195_P281_A1.3330.47
164_F167_Q1.3310.47
348_F362_G1.3310.47
223_F260_V1.3290.47
148_L285_F1.3280.47
536_A580_S1.3280.47
567_L571_H1.3150.46
331_F446_Q1.3120.46
583_V591_L1.3110.46
216_I267_T1.3090.46
101_D472_K1.3030.46
72_V523_I1.3020.46
269_D273_N1.2930.45
282_I292_I1.2860.45
73_E81_G1.2850.45
112_A469_F1.2840.45
434_M457_H1.2780.44
135_L174_V1.2750.44
195_P285_F1.2730.44
170_L203_F1.2600.43
426_A464_G1.2580.43
45_N553_M1.2560.43
145_T163_F1.2530.43
528_C546_G1.2500.43
24_I532_T1.2470.43
338_D403_W1.2350.42
320_L546_G1.2260.42
138_L174_V1.2220.41
19_L37_I1.2200.41
109_I253_N1.2170.41
112_A466_L1.1900.40
260_V264_I1.1870.40
263_I266_R1.1850.40
517_A524_D1.1850.40
48_S532_T1.1840.40
492_P495_W1.1820.39
402_R544_Q1.1780.39
435_M444_G1.1770.39
338_D404_R1.1770.39
352_A396_S1.1740.39
301_V417_L1.1740.39
195_P198_A1.1620.38
222_V259_L1.1570.38
257_L474_M1.1560.38
21_V566_I1.1560.38
87_S503_G1.1560.38
420_Y423_G1.1480.38
201_M281_A1.1440.38
50_G580_S1.1390.37
219_I466_L1.1380.37
402_R407_A1.1360.37
242_N245_E1.1250.37
305_G458_E1.1250.37
416_T427_T1.1220.36
537_S540_D1.1220.36
223_F239_C1.1210.36
82_V114_L1.1190.36
294_T329_G1.1160.36
68_A551_A1.1100.36
280_L437_A1.1020.35
320_L469_F1.1000.35
51_T490_W1.1000.35
302_L408_M1.1000.35
82_V505_T1.0960.35
144_K148_L1.0950.35
590_E595_Q1.0930.35
331_F444_G1.0920.35
345_V516_A1.0840.35
125_Q209_A1.0830.35
441_P457_H1.0810.34
222_V263_I1.0810.34
261_Q467_Q1.0810.34
73_E84_A1.0800.34
296_L550_A1.0730.34
58_I61_Q1.0730.34
445_I520_D1.0670.34
431_V445_I1.0670.34
516_A526_Y1.0620.34
18_R391_E1.0610.33
342_P502_V1.0530.33
579_C582_H1.0480.33
20_V51_T1.0470.33
181_I400_A1.0470.33
53_F58_I1.0430.33
255_E522_K1.0420.33
431_V442_L1.0410.33
426_A468_Y1.0320.32
106_I265_T1.0310.32
106_I577_L1.0300.32
348_F541_P1.0280.32
548_Y564_L1.0260.32
446_Q453_L1.0240.32
468_Y472_K1.0200.32
389_L409_E1.0180.31
355_R359_D1.0180.31
117_H400_A1.0160.31
139_K167_Q1.0140.31
145_T281_A1.0140.31
264_I470_F1.0100.31
127_A192_Y1.0100.31
146_S478_K1.0100.31
327_I406_N1.0060.31
41_N557_M1.0050.31
132_I194_L1.0000.31
82_V111_L0.9980.31
528_C564_L0.9970.31
430_S460_Q0.9960.30
300_C408_M0.9960.30
458_E506_E0.9940.30
168_N171_K0.9930.30
364_H444_G0.9890.30
208_E211_D0.9880.30
189_H558_A0.9880.30
274_V289_W0.9850.30
150_Q158_S0.9840.30
336_P403_W0.9810.30
409_E511_A0.9810.30
489_K495_W0.9800.30
161_G225_G0.9790.30
149_A152_L0.9770.30
238_P260_V0.9740.30
86_A407_A0.9720.29
346_Q362_G0.9670.29
575_P579_C0.9610.29
576_C579_C0.9610.29
461_W465_K0.9610.29
374_Y529_V0.9600.29
232_W403_W0.9550.29
50_G398_I0.9550.29
58_I73_E0.9520.29
302_L410_V0.9500.28
436_S439_N0.9480.28
322_P419_A0.9450.28
494_T497_T0.9440.28
465_K468_Y0.9380.28
120_L267_T0.9380.28
276_I405_G0.9370.28
125_Q287_K0.9360.28
93_D340_V0.9350.28
475_T478_K0.9350.28
348_F478_K0.9340.28
426_A465_K0.9320.28
238_P336_P0.9310.28
524_D583_V0.9290.28
495_W499_C0.9290.28
209_A270_F0.9260.27
338_D344_Q0.9260.27
112_A116_C0.9230.27
221_A231_N0.9220.27
111_L505_T0.9210.27
574_D579_C0.9190.27
68_A72_V0.9180.27
301_V446_Q0.9160.27
295_G507_A0.9140.27
269_D516_A0.9140.27
390_N479_N0.9110.27
150_Q161_G0.9090.27
536_A564_L0.9050.27
86_A561_E0.9050.27
23_P26_R0.9050.27
163_F227_N0.9040.27
168_N172_K0.9040.27
154_S273_N0.9030.26
339_L422_K0.8990.26
135_L175_E0.8950.26
21_V497_T0.8930.26
256_R259_L0.8900.26
41_N583_V0.8880.26
140_A200_L0.8870.26
56_L551_A0.8860.26
342_P366_F0.8860.26
185_G345_V0.8790.26
427_T553_M0.8780.25
276_I456_A0.8760.25
24_I33_C0.8760.25
237_M525_L0.8730.25
445_I449_L0.8720.25
481_N517_A0.8710.25
300_C421_H0.8680.25
84_A394_R0.8670.25
254_M258_N0.8650.25
54_R57_E0.8630.25
460_Q464_G0.8590.25
367_D517_A0.8590.25
74_R79_C0.8580.25
267_T466_L0.8560.25
532_T536_A0.8540.25
346_Q349_V0.8540.25
43_I120_L0.8540.25
431_V435_M0.8540.25
161_G165_D0.8530.24
409_E555_T0.8510.24
108_N469_F0.8510.24
162_Y220_H0.8510.24
99_V319_L0.8460.24
116_C466_L0.8460.24
104_N305_G0.8460.24
152_L281_A0.8430.24
430_S434_M0.8430.24
85_L89_Y0.8420.24
302_L511_A0.8410.24
84_A89_Y0.8390.24
143_R371_D0.8380.24
151_S155_W0.8370.24
220_H227_N0.8360.24
87_S529_V0.8360.24
528_C548_Y0.8310.24
233_I303_S0.8300.24
201_M440_L0.8290.24
47_V581_T0.8280.24
161_G344_Q0.8280.24
99_V494_T0.8250.23
330_D374_Y0.8250.23
440_L444_G0.8240.23
398_I528_C0.8240.23
162_Y208_E0.8230.23
155_W208_E0.8230.23
336_P341_D0.8180.23
45_N539_R0.8170.23
103_A140_A0.8150.23
415_R506_E0.8100.23
70_A234_V0.8050.23
99_V273_N0.8040.23
62_G88_V0.8010.23
407_A547_A0.8010.23
43_I47_V0.8000.22
212_F216_I0.7990.22
352_A400_A0.7980.22
61_Q519_R0.7960.22
38_N44_T0.7950.22
114_L532_T0.7950.22
321_M414_A0.7930.22
466_L469_F0.7920.22
89_Y306_A0.7900.22
242_N254_M0.7890.22
243_I482_L0.7880.22
343_Q404_R0.7860.22
165_D168_N0.7860.22
321_M341_D0.7850.22
202_G281_A0.7820.22
192_Y452_I0.7820.22
184_N555_T0.7800.22
116_C345_V0.7800.22
194_L277_P0.7780.22
237_M489_K0.7770.22
61_Q524_D0.7740.22
144_K197_E0.7720.21
149_A263_I0.7710.21
82_V117_H0.7700.21
545_I550_A0.7700.21
60_L345_V0.7690.21
133_D559_I0.7670.21
294_T297_S0.7650.21
134_V152_L0.7630.21
134_V199_N0.7620.21
575_P582_H0.7610.21
576_C582_H0.7610.21
316_E319_L0.7610.21
303_S506_E0.7590.21
444_G449_L0.7590.21
155_W159_S0.7560.21
135_L203_F0.7550.21
326_V550_A0.7540.21
588_G591_L0.7530.21
20_V323_G0.7530.21
156_P208_E0.7530.21
51_T66_R0.7520.21
133_D270_F0.7480.21
497_T520_D0.7470.21
86_A111_L0.7460.21
181_I232_W0.7440.20
280_L438_L0.7420.20
116_C352_A0.7420.20
491_E494_T0.7420.20
148_L152_L0.7410.20
219_I238_P0.7410.20
62_G523_I0.7390.20
490_W493_A0.7390.20
349_V361_V0.7370.20
155_W158_S0.7370.20
101_D104_N0.7350.20
155_W273_N0.7350.20
142_P167_Q0.7330.20
372_P397_W0.7330.20
75_I548_Y0.7320.20
275_M525_L0.7320.20
101_D504_F0.7310.20
473_L476_N0.7310.20
84_A255_E0.7300.20
67_D177_G0.7290.20
323_G422_K0.7290.20
480_G569_T0.7280.20
217_V237_M0.7280.20
150_Q159_S0.7280.20
189_H565_E0.7260.20
303_S415_R0.7250.20
217_V220_H0.7250.20
231_N569_T0.7240.20
413_L435_M0.7230.20
242_N246_S0.7210.20
545_I553_M0.7210.20
574_D582_H0.7190.20
186_Y270_F0.7180.20
364_H368_G0.7170.20
538_P578_A0.7160.20
133_D221_A0.7150.19
217_V221_A0.7150.19
272_N430_S0.7140.19
96_G99_V0.7130.19
280_L434_M0.7110.19
427_T430_S0.7100.19
33_C581_T0.7090.19
405_G542_K0.7070.19
210_L213_Q0.7050.19
409_E538_P0.7040.19
266_R475_T0.7030.19
61_Q520_D0.7020.19
410_V530_V0.7010.19
22_D32_R0.7010.19
128_G423_G0.6990.19
33_C570_L0.6980.19
262_S265_T0.6960.19
33_C430_S0.6950.19
20_V230_P0.6940.19
498_E517_A0.6920.19
149_A155_W0.6920.19
133_D184_N0.6900.19
146_S159_S0.6890.19
366_F453_L0.6890.19
322_P345_V0.6890.19
102_N397_W0.6890.19
85_L225_G0.6880.19
223_F234_V0.6880.19
218_K258_N0.6870.19
73_E271_I0.6870.19
309_D468_Y0.6870.19
95_I131_W0.6870.19
75_I546_G0.6840.18
151_S154_S0.6840.18
53_F581_T0.6830.18
181_I185_G0.6820.18
92_E95_I0.6810.18
179_L452_I0.6790.18
97_I494_T0.6790.18
305_G323_G0.6790.18
36_N581_T0.6780.18
192_Y458_E0.6770.18
432_D542_K0.6760.18
110_M233_I0.6760.18
465_K469_F0.6760.18
272_N330_D0.6750.18
225_G245_E0.6750.18
233_I242_N0.6740.18
140_A571_H0.6720.18
54_R76_C0.6720.18
57_E76_C0.6720.18
117_H178_Q0.6700.18
32_R224_G0.6670.18
170_L567_L0.6660.18
84_A219_I0.6660.18
55_G76_C0.6650.18
34_E192_Y0.6640.18
223_F238_P0.6640.18
31_M580_S0.6630.18
335_L344_Q0.6630.18
309_D318_S0.6620.18
443_S593_S0.6620.18
139_K406_N0.6620.18
157_K208_E0.6620.18
37_I44_T0.6610.18
180_G184_N0.6610.18
157_K546_G0.6600.18
92_E594_V0.6590.18
30_H78_V0.6590.18
214_R588_G0.6570.18
121_V394_R0.6560.18
272_N433_R0.6560.18
338_D341_D0.6540.18
80_T118_D0.6540.18
89_Y503_G0.6540.18
99_V341_D0.6530.18
584_L591_L0.6530.18
154_S269_D0.6500.17
234_V305_G0.6490.17
490_W494_T0.6490.17
85_L176_G0.6490.17
263_I320_L0.6480.17
136_D564_L0.6480.17
115_W307_F0.6470.17
581_T585_G0.6460.17
56_L72_V0.6450.17
24_I330_D0.6450.17
48_S302_L0.6450.17
270_F274_V0.6440.17
214_R536_A0.6440.17
217_V489_K0.6430.17
69_W81_G0.6420.17
500_R591_L0.6420.17
242_N255_E0.6410.17
132_I423_G0.6400.17
108_N507_A0.6400.17
214_R528_C0.6390.17
355_R532_T0.6380.17
491_E495_W0.6370.17
53_F110_M0.6360.17
85_L503_G0.6360.17
103_A137_A0.6360.17
95_I364_H0.6350.17
52_M594_V0.6350.17
116_C267_T0.6340.17
462_A581_T0.6340.17
181_I198_A0.6320.17
185_G201_M0.6320.17
136_D188_G0.6320.17
421_H425_A0.6320.17
128_G282_I0.6310.17
62_G128_G0.6290.17
272_N345_V0.6290.17
69_W91_I0.6290.17
346_Q513_G0.6280.17
175_E326_V0.6260.17
406_N542_K0.6260.17
127_A275_M0.6250.17
363_R519_R0.6250.17
89_Y289_W0.6240.17
69_W241_I0.6240.17
72_V577_L0.6230.17
109_I414_A0.6230.17
156_P159_S0.6230.17
146_S160_P0.6230.17
227_N420_Y0.6220.17
211_D348_F0.6220.17
20_V134_V0.6210.17
366_F488_E0.6210.17
536_A585_G0.6210.17
104_N472_K0.6200.17
300_C331_F0.6200.17
114_L305_G0.6180.16
349_V368_G0.6180.16
326_V454_C0.6180.16
173_F453_L0.6170.16
477_L482_L0.6160.16
350_D543_G0.6160.16
53_F202_G0.6160.16
416_T457_H0.6150.16
416_T461_W0.6150.16
59_I80_T0.6150.16
110_M232_W0.6150.16
181_I201_M0.6140.16
23_P27_I0.6130.16
555_T569_T0.6130.16
294_T391_E0.6130.16
54_R77_G0.6120.16
57_E77_G0.6120.16
153_S209_A0.6120.16
491_E497_T0.6120.16
87_S372_P0.6120.16
338_D342_P0.6100.16
262_S467_Q0.6100.16
150_Q163_F0.6090.16
294_T555_T0.6090.16
240_A253_N0.6090.16
281_A285_F0.6080.16
490_W499_C0.6070.16
161_G346_Q0.6070.16
307_F469_F0.6060.16
160_P172_K0.6060.16
51_T495_W0.6040.16
93_D96_G0.6040.16
55_G77_G0.6030.16
489_K499_C0.6030.16
115_W507_A0.6030.16
146_S165_D0.6020.16
493_A520_D0.6010.16
90_A436_S0.6010.16
213_Q571_H0.6010.16
106_I481_N0.6010.16
88_V178_Q0.6010.16
21_V578_A0.6010.16
584_L588_G0.6010.16
155_W238_P0.6000.16
171_K390_N0.6000.16
171_K407_A0.6000.16
97_I513_G0.6000.16
264_I542_K0.5980.16
56_L583_V0.5980.16
233_I477_L0.5970.16
76_C79_C0.5960.16
425_A439_N0.5960.16
352_A425_A0.5950.16
167_Q175_E0.5930.16
54_R74_R0.5920.16
57_E74_R0.5920.16
54_R79_C0.5920.16
57_E79_C0.5920.16
321_M424_D0.5920.16
50_G295_G0.5910.16
125_Q459_A0.5910.16
102_N473_L0.5910.16
153_S274_V0.5910.16
535_N538_P0.5900.16
97_I500_R0.5880.16
489_K493_A0.5880.16
104_N403_W0.5870.16
338_D481_N0.5860.16
216_I489_K0.5850.16
272_N283_G0.5850.16
375_N406_N0.5850.16
255_E259_L0.5850.16
128_G281_A0.5830.15
310_I478_K0.5830.15
31_M49_C0.5830.15
416_T419_A0.5830.15
320_L465_K0.5830.15
242_N502_V0.5820.15
19_L189_H0.5820.15
257_L470_F0.5810.15
137_A200_L0.5800.15
99_V306_A0.5800.15
343_Q346_Q0.5790.15
515_W530_V0.5780.15
38_N283_G0.5780.15
164_F542_K0.5770.15
297_S472_K0.5770.15
339_L559_I0.5770.15
136_D173_F0.5770.15
231_N448_T0.5760.15
409_E496_P0.5750.15
108_N305_G0.5750.15
288_P454_C0.5740.15
537_S577_L0.5730.15
184_N188_G0.5730.15
98_K517_A0.5720.15
456_A464_G0.5710.15
430_S433_R0.5700.15
86_A280_L0.5700.15
529_V540_D0.5700.15
257_L404_R0.5690.15
23_P76_C0.5690.15
26_R76_C0.5690.15
309_D472_K0.5670.15
26_R57_E0.5670.15
26_R54_R0.5670.15
23_P57_E0.5670.15
23_P54_R0.5670.15
191_Q292_I0.5660.15
410_V560_P0.5660.15
371_D427_T0.5650.15
588_G594_V0.5630.15
168_N407_A0.5620.15
326_V331_F0.5610.15
26_R30_H0.5610.15
23_P30_H0.5610.15
532_T537_S0.5610.15
31_M570_L0.5600.15
191_Q556_K0.5590.15
584_L590_E0.5590.15
268_A467_Q0.5590.15
279_A551_A0.5570.15
109_I120_L0.5570.15
340_V504_F0.5570.15
319_L323_G0.5550.15
296_L409_E0.5550.15
109_I453_L0.5550.15
391_E472_K0.5540.15
149_A441_P0.5540.15
143_R346_Q0.5540.15
322_P511_A0.5530.15
98_K222_V0.5530.15
181_I389_L0.5530.15
109_I113_T0.5530.15
109_I134_V0.5520.15
307_F466_L0.5520.15
33_C554_N0.5520.15
285_F444_G0.5520.15
35_V45_N0.5520.15
245_E326_V0.5510.15
135_L555_T0.5500.15
21_V56_L0.5490.15
240_A254_M0.5480.15
239_C267_T0.5480.15
143_R392_Q0.5470.15
346_Q367_D0.5460.14
37_I41_N0.5460.14
35_V181_I0.5460.14
96_G521_G0.5440.14
435_M446_Q0.5440.14
252_V296_L0.5440.14
82_V271_I0.5440.14
305_G415_R0.5430.14
169_R425_A0.5430.14
268_A466_L0.5420.14
109_I168_N0.5410.14
219_I264_I0.5410.14
255_E557_M0.5400.14
157_K167_Q0.5400.14
46_A90_A0.5400.14
51_T577_L0.5390.14
69_W84_A0.5380.14
335_L403_W0.5380.14
200_L450_G0.5380.14
74_R77_G0.5370.14
18_R21_V0.5370.14
371_D398_I0.5370.14
505_T528_C0.5360.14
44_T561_E0.5360.14
209_A526_Y0.5360.14
81_G225_G0.5360.14
360_Q532_T0.5360.14
134_V562_Q0.5350.14
45_N297_S0.5350.14
348_F405_G0.5350.14
287_K439_N0.5350.14
325_A337_V0.5340.14
96_G472_K0.5340.14
435_M457_H0.5340.14
107_R563_P0.5340.14
82_V87_S0.5330.14
233_I474_M0.5330.14
225_G506_E0.5320.14
303_S584_L0.5310.14
137_A140_A0.5310.14
277_P349_V0.5300.14
361_V368_G0.5300.14
234_V490_W0.5280.14
62_G72_V0.5280.14
305_G322_P0.5280.14
133_D218_K0.5270.14
489_K492_P0.5270.14
65_P78_V0.5270.14
157_K181_I0.5270.14
283_G561_E0.5270.14
304_Y398_I0.5250.14
22_D30_H0.5250.14
17_R93_D0.5250.14
92_E230_P0.5250.14
96_G172_K0.5240.14
155_W259_L0.5240.14
36_N44_T0.5230.14
98_K519_R0.5230.14
50_G581_T0.5220.14
104_N232_W0.5220.14
145_T162_Y0.5210.14
134_V149_A0.5210.14
135_L436_S0.5210.14
131_W195_P0.5200.14
325_A344_Q0.5180.14
346_Q405_G0.5180.14
352_A369_I0.5180.14
301_V556_K0.5170.14
491_E496_P0.5170.14
327_I408_M0.5170.14
127_A230_P0.5160.14
307_F471_D0.5160.14
187_W526_Y0.5150.14
267_T418_I0.5150.14
436_S500_R0.5150.14
212_F267_T0.5150.14
457_H479_N0.5150.14
33_C590_E0.5140.14
184_N290_S0.5140.14
166_V524_D0.5140.14
321_M461_W0.5130.14
292_I556_K0.5130.14
88_V583_V0.5120.14
254_M391_E0.5120.14
192_Y252_V0.5120.14
90_A315_G0.5120.14
307_F470_F0.5110.14
286_N450_G0.5110.14
350_D594_V0.5110.14
183_R547_A0.5100.14
105_I473_L0.5100.14
329_G550_A0.5090.14
159_S273_N0.5070.13
566_I583_V0.5070.13
350_D410_V0.5060.13
359_D363_R0.5050.13
47_V391_E0.5050.13
23_P77_G0.5050.13
26_R77_G0.5050.13
105_I472_K0.5040.13
32_R182_F0.5020.13
355_R369_I0.5020.13
264_I537_S0.5020.13
37_I578_A0.5010.13
91_I275_M0.5000.13
116_C475_T0.5000.13
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ayxA 2 0.9682 100 0.321 Contact Map
4ue3L 2 0.9715 100 0.373 Contact Map
4c3oA 2 0.9715 100 0.377 Contact Map
3myrB 2 0.9363 100 0.38 Contact Map
4uqlQ 1 0.9012 100 0.411 Contact Map
4u9hL 1 0.8878 100 0.415 Contact Map
1e3dB 1 0.8911 100 0.42 Contact Map
1yq9H 1 0.8827 100 0.428 Contact Map
4kn9L 2 0.7889 100 0.541 Contact Map
3ze9B 1 0.7923 100 0.552 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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