DNAB - ECOLI - GREMLIN Contacts

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DNAB - Replicative DNA helicase

UniProt:	P0ACB0	Sequences: MAGNKPFNKQQAEPRERDPQVAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGFAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDLAESRVFKIAESRANKDEGPKNIADVLDATVARIEQLFQQPHDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTMGILLEKRNIYIDDSSGLTPTEVRSRARRIAREHGGIGLIMIDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYAGPQYDDE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10236
Length:	471 (434)
Sequences:	3939 (2641)
Seq/√Len:	126.8

ECOLI - DNAB
BACSU - DNAC YORI

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
388_S	391_Q	4.161	1.00
59_D	130_A	3.509	1.00
327_A	340_I	3.414	1.00
212_D	462_N	3.396	1.00
223_P	376_N	3.354	1.00
141_E	164_R	3.190	1.00
209_T	221_L	3.183	1.00
283_K	293_D	3.150	1.00
57_A	70_T	2.954	1.00
254_K	338_G	2.854	1.00
255_P	338_G	2.850	1.00
225_D	267_Q	2.771	1.00
399_N	415_I	2.723	1.00
240_F	244_L	2.636	1.00
248_A	339_L	2.595	1.00
452_T	463_Y	2.531	1.00
396_R	435_E	2.487	1.00
430_L	450_R	2.458	1.00
422_E	432_G	2.397	1.00
257_L	330_I	2.363	1.00
418_I	436_I	2.305	1.00
180_K	265_S	2.300	1.00
217_K	447_G	2.292	1.00
245_V	341_M	2.250	1.00
340_I	377_V	2.236	1.00
188_A	266_E	2.230	1.00
208_N	215_N	2.214	1.00
90_S	93_R	2.211	1.00
365_S	411_D	2.202	1.00
78_S	90_S	2.149	1.00
433_I	450_R	2.110	1.00
231_A	418_I	2.085	1.00
392_R	401_D	2.034	1.00
228_I	412_A	2.002	1.00
72_M	82_I	1.999	1.00
234_S	443_N	1.996	1.00
417_F	439_G	1.968	1.00
313_D	326_R	1.961	1.00
255_P	309_N	1.956	1.00
320_P	367_S	1.951	1.00
214_L	416_M	1.939	1.00
182_I	269_M	1.934	1.00
311_Y	334_H	1.913	1.00
130_A	134_E	1.910	1.00
218_T	414_L	1.904	1.00
229_V	380_V	1.883	1.00
454_N	461_D	1.881	1.00
74_R	94_Q	1.877	1.00
327_A	375_L	1.873	1.00
42_M	87_L	1.862	1.00
421_D	425_H	1.845	1.00
357_R	360_E	1.837	1.00
357_R	404_E	1.817	1.00
280_D	283_K	1.810	1.00
226_L	368_L	1.783	1.00
235_M	423_V	1.778	1.00
331_A	336_G	1.767	1.00
211_Y	451_L	1.752	1.00
74_R	90_S	1.751	1.00
323_V	348_M	1.749	1.00
54_R	123_A	1.741	1.00
210_G	215_N	1.729	1.00
235_M	424_Y	1.728	1.00
181_N	184_D	1.713	1.00
48_W	73_A	1.708	1.00
90_S	94_Q	1.689	1.00
250_M	308_R	1.688	1.00
246_E	276_L	1.675	1.00
228_I	408_I	1.667	1.00
191_A	195_Q	1.660	1.00
41_L	48_W	1.660	1.00
231_A	235_M	1.648	1.00
194_E	198_Q	1.618	1.00
292_E	296_R	1.611	1.00
71_E	90_S	1.605	1.00
145_A	160_L	1.590	1.00
433_I	463_Y	1.583	1.00
249_A	310_I	1.574	1.00
441_Q	445_P	1.568	1.00
207_V	248_A	1.555	1.00
414_L	441_Q	1.553	1.00
341_M	380_V	1.549	1.00
97_L	101_G	1.548	1.00
38_L	65_H	1.537	1.00
365_S	381_A	1.531	1.00
129_R	132_V	1.527	1.00
277_S	457_W	1.523	1.00
241_A	341_M	1.522	1.00
136_I	146_G	1.521	1.00
217_K	438_I	1.517	1.00
89_E	93_R	1.514	1.00
273_L	297_I	1.512	1.00
362_A	407_S	1.508	1.00
192_R	266_E	1.507	1.00
68_I	105_Y	1.505	1.00
192_R	196_L	1.499	1.00
163_S	167_K	1.494	1.00
88_A	106_L	1.488	1.00
139_A	142_I	1.487	1.00
37_V	126_V	1.486	1.00
223_P	338_G	1.485	1.00
278_R	457_W	1.474	1.00
26_V	29_H	1.472	1.00
179_P	257_L	1.466	1.00
57_A	73_A	1.457	1.00
58_D	66_R	1.455	1.00
153_T	156_D	1.454	1.00
435_E	448_T	1.453	1.00
35_Q	105_Y	1.452	1.00
41_L	72_M	1.450	1.00
59_D	127_R	1.433	1.00
134_E	137_S	1.432	1.00
37_V	55_V	1.418	1.00
276_L	303_I	1.417	1.00
185_V	265_S	1.415	1.00
71_E	87_L	1.411	1.00
224_S	264_P	1.410	1.00
239_T	271_R	1.407	1.00
63_R	66_R	1.404	1.00
69_F	73_A	1.386	1.00
28_P	136_I	1.376	1.00
205_T	222_Q	1.375	1.00
120_S	124_D	1.371	1.00
67_H	96_Q	1.369	1.00
142_I	161_A	1.361	1.00
239_T	458_S	1.360	1.00
193_I	297_I	1.355	1.00
229_V	240_F	1.352	1.00
339_L	380_V	1.348	1.00
35_Q	112_N	1.348	1.00
213_D	216_K	1.345	1.00
437_I	448_T	1.344	1.00
114_P	122_Y	1.343	1.00
358_T	362_A	1.336	1.00
213_D	462_N	1.335	1.00
346_Q	383_S	1.329	1.00
164_R	167_K	1.327	1.00
54_R	124_D	1.325	1.00
221_L	339_L	1.323	1.00
139_A	143_A	1.318	1.00
47_R	119_I	1.317	1.00
274_A	284_I	1.317	1.00
257_L	340_I	1.317	1.00
285_R	441_Q	1.316	1.00
31_I	62_T	1.316	1.00
246_E	275_S	1.301	1.00
234_S	446_I	1.301	1.00
454_N	457_W	1.298	1.00
280_D	456_Q	1.296	1.00
41_L	51_V	1.293	1.00
127_R	131_V	1.289	1.00
257_L	327_A	1.287	1.00
245_V	258_I	1.285	1.00
419_Y	424_Y	1.278	1.00
139_A	146_G	1.263	1.00
434_A	460_F	1.262	1.00
323_V	342_I	1.254	1.00
208_N	252_Q	1.249	1.00
62_T	65_H	1.245	1.00
324_R	374_E	1.242	1.00
249_A	256_V	1.236	1.00
416_M	436_I	1.235	1.00
255_P	336_G	1.233	1.00
140_N	143_A	1.228	0.99
441_Q	444_G	1.226	0.99
221_L	244_L	1.225	0.99
355_D	359_L	1.221	0.99
244_L	248_A	1.220	0.99
242_M	272_S	1.217	0.99
396_R	448_T	1.214	0.99
70_T	74_R	1.209	0.99
189_T	193_I	1.208	0.99
222_Q	225_D	1.198	0.99
33_A	126_V	1.198	0.99
240_F	436_I	1.188	0.99
88_A	92_E	1.182	0.99
331_A	337_I	1.182	0.99
331_A	376_N	1.181	0.99
452_T	461_D	1.175	0.99
278_R	459_R	1.174	0.99
403_R	410_Q	1.174	0.99
371_L	375_L	1.167	0.99
234_S	440_K	1.167	0.99
201_H	288_Q	1.165	0.99
40_G	119_I	1.157	0.99
96_Q	99_S	1.155	0.99
241_A	382_L	1.155	0.99
25_K	147_F	1.150	0.99
160_L	163_S	1.142	0.99
258_I	310_I	1.138	0.99
189_T	270_M	1.138	0.99
60_F	69_F	1.136	0.99
160_L	164_R	1.135	0.99
356_N	359_L	1.130	0.99
180_K	185_V	1.127	0.99
224_S	376_N	1.117	0.99
386_N	389_L	1.115	0.99
253_D	307_K	1.105	0.99
225_D	443_N	1.104	0.99
279_V	297_I	1.102	0.99
212_D	216_K	1.101	0.99
33_A	125_I	1.098	0.99
283_K	290_D	1.097	0.99
136_I	147_F	1.095	0.99
247_N	252_Q	1.093	0.99
454_N	459_R	1.092	0.99
290_D	293_D	1.090	0.99
30_S	89_E	1.090	0.99
35_Q	65_H	1.084	0.99
245_V	256_V	1.077	0.99
137_S	141_E	1.074	0.99
119_I	123_A	1.060	0.98
311_Y	330_I	1.055	0.98
51_V	123_A	1.054	0.98
318_L	323_V	1.052	0.98
293_D	296_R	1.039	0.98
396_R	437_I	1.034	0.98
327_A	379_V	1.032	0.98
180_K	188_A	1.032	0.98
389_L	423_V	1.029	0.98
97_L	102_G	1.020	0.98
289_L	297_I	1.016	0.98
195_Q	198_Q	1.006	0.98
195_Q	199_Q	1.005	0.98
39_G	113_T	1.002	0.98
428_S	431_K	1.001	0.98
138_V	164_R	0.999	0.98
132_V	157_L	0.997	0.98
345_L	408_I	0.996	0.98
302_G	307_K	0.988	0.98
403_R	406_G	0.987	0.98
124_D	128_E	0.987	0.98
65_H	105_Y	0.984	0.98
192_R	195_Q	0.983	0.98
103_F	107_A	0.982	0.98
371_L	379_V	0.980	0.97
392_R	398_V	0.978	0.97
277_S	300_T	0.975	0.97
51_V	119_I	0.975	0.97
50_D	120_S	0.970	0.97
387_R	409_E	0.970	0.97
292_E	295_A	0.963	0.97
127_R	130_A	0.961	0.97
342_I	368_L	0.960	0.97
211_Y	243_N	0.960	0.97
257_L	377_V	0.958	0.97
232_R	390_E	0.958	0.97
89_E	125_I	0.957	0.97
254_K	336_G	0.956	0.97
89_E	92_E	0.955	0.97
390_E	395_K	0.955	0.97
189_T	273_L	0.951	0.97
238_T	268_I	0.951	0.97
141_E	145_A	0.949	0.97
249_A	308_R	0.948	0.97
125_I	129_R	0.948	0.97
219_A	286_T	0.946	0.97
234_S	399_N	0.944	0.97
35_Q	108_E	0.942	0.97
180_K	184_D	0.938	0.97
248_A	254_K	0.936	0.97
386_N	415_I	0.933	0.97
420_R	424_Y	0.932	0.97
355_D	358_T	0.932	0.97
63_R	67_H	0.932	0.97
315_S	318_L	0.931	0.97
49_D	76_Q	0.929	0.97
88_A	97_L	0.929	0.97
235_M	434_A	0.921	0.96
421_D	428_S	0.919	0.96
386_N	423_V	0.916	0.96
84_L	88_A	0.916	0.96
48_W	52_A	0.914	0.96
389_L	395_K	0.912	0.96
227_I	414_L	0.912	0.96
222_Q	285_R	0.912	0.96
274_A	280_D	0.904	0.96
185_V	269_M	0.902	0.96
242_M	258_I	0.902	0.96
32_E	35_Q	0.897	0.96
48_W	76_Q	0.893	0.96
418_I	434_A	0.893	0.96
218_T	438_I	0.889	0.96
395_K	424_Y	0.889	0.96
55_V	60_F	0.888	0.96
179_P	330_I	0.886	0.95
186_L	301_M	0.886	0.95
197_F	294_W	0.885	0.95
162_E	166_F	0.884	0.95
232_R	409_E	0.881	0.95
278_R	461_D	0.880	0.95
261_L	318_L	0.878	0.95
74_R	78_S	0.876	0.95
131_V	158_L	0.874	0.95
214_L	436_I	0.873	0.95
28_P	61_Y	0.868	0.95
369_K	413_D	0.864	0.95
246_E	272_S	0.860	0.95
282_T	286_T	0.859	0.95
58_D	134_E	0.855	0.95
59_D	134_E	0.855	0.95
29_H	61_Y	0.854	0.94
226_L	365_S	0.853	0.94
108_E	111_K	0.849	0.94
347_L	411_D	0.848	0.94
30_S	129_R	0.848	0.94
276_L	300_T	0.844	0.94
387_R	406_G	0.844	0.94
233_P	409_E	0.843	0.94
28_P	147_F	0.841	0.94
104_A	108_E	0.840	0.94
191_A	194_E	0.838	0.94
428_S	433_I	0.837	0.94
242_M	268_I	0.833	0.94
45_N	82_I	0.833	0.94
104_A	107_A	0.833	0.94
422_E	455_G	0.829	0.94
365_S	407_S	0.827	0.93
358_T	404_E	0.826	0.93
82_I	86_T	0.824	0.93
240_F	418_I	0.822	0.93
84_L	107_A	0.821	0.93
145_A	164_R	0.821	0.93
140_N	144_E	0.819	0.93
406_G	409_E	0.814	0.93
138_V	165_V	0.809	0.93
188_A	191_A	0.809	0.93
362_A	366_R	0.808	0.93
370_A	373_K	0.808	0.93
68_I	106_L	0.803	0.92
138_V	168_I	0.802	0.92
41_L	45_N	0.797	0.92
422_E	431_K	0.793	0.92
432_G	452_T	0.791	0.92
40_G	116_A	0.790	0.92
229_V	241_A	0.790	0.92
399_N	439_G	0.789	0.92
196_L	270_M	0.787	0.92
159_D	163_S	0.787	0.92
256_V	339_L	0.786	0.92
299_G	303_I	0.784	0.92
38_L	109_L	0.784	0.92
239_T	242_M	0.782	0.91
118_N	121_A	0.781	0.91
56_V	59_D	0.776	0.91
209_T	215_N	0.776	0.91
73_A	77_E	0.775	0.91
339_L	378_P	0.773	0.91
45_N	87_L	0.772	0.91
338_G	377_V	0.771	0.91
407_S	411_D	0.770	0.91
245_V	249_A	0.769	0.91
257_L	337_I	0.769	0.91
226_L	381_A	0.768	0.91
70_T	96_Q	0.767	0.91
234_S	414_L	0.766	0.91
450_R	463_Y	0.764	0.90
435_E	450_R	0.762	0.90
156_D	159_D	0.760	0.90
422_E	428_S	0.759	0.90
246_E	250_M	0.755	0.90
259_F	340_I	0.754	0.90
118_N	122_Y	0.753	0.90
185_V	189_T	0.751	0.90
214_L	438_I	0.751	0.90
230_A	385_L	0.749	0.90
267_Q	443_N	0.748	0.90
178_G	326_R	0.748	0.90
52_A	76_Q	0.746	0.89
156_D	160_L	0.744	0.89
67_H	70_T	0.740	0.89
248_A	256_V	0.738	0.89
309_N	338_G	0.737	0.89
430_L	433_I	0.736	0.89
199_Q	202_D	0.736	0.89
390_E	400_S	0.735	0.89
368_L	381_A	0.735	0.89
83_D	122_Y	0.734	0.89
31_I	35_Q	0.731	0.88
425_H	428_S	0.730	0.88
318_L	326_R	0.730	0.88
132_V	146_G	0.729	0.88
261_L	347_L	0.728	0.88
192_R	270_M	0.727	0.88
67_H	100_V	0.727	0.88
44_D	116_A	0.726	0.88
282_T	445_P	0.726	0.88
47_R	50_D	0.722	0.88
351_P	363_E	0.721	0.88
166_F	170_E	0.721	0.88
224_S	267_Q	0.720	0.88
232_R	387_R	0.719	0.88
342_I	379_V	0.716	0.87
214_L	221_L	0.716	0.87
245_V	310_I	0.713	0.87
399_N	417_F	0.711	0.87
412_A	415_I	0.711	0.87
314_D	373_K	0.709	0.87
318_L	322_E	0.708	0.87
75_L	80_S	0.708	0.87
217_K	441_Q	0.707	0.87
76_Q	82_I	0.706	0.87
71_E	74_R	0.706	0.87
80_S	124_D	0.706	0.87
358_T	407_S	0.705	0.87
358_T	386_N	0.703	0.86
238_T	242_M	0.702	0.86
233_P	406_G	0.698	0.86
247_N	251_L	0.696	0.86
327_A	337_I	0.693	0.86
128_E	153_T	0.693	0.86
92_E	97_L	0.692	0.86
361_I	405_S	0.690	0.85
342_I	381_A	0.689	0.85
152_R	156_D	0.688	0.85
83_D	118_N	0.687	0.85
298_S	302_G	0.686	0.85
167_K	170_E	0.685	0.85
189_T	269_M	0.682	0.85
233_P	390_E	0.682	0.85
221_L	248_A	0.681	0.85
436_I	451_L	0.681	0.85
30_S	33_A	0.680	0.85
57_A	66_R	0.679	0.84
420_R	434_A	0.678	0.84
253_D	309_N	0.678	0.84
243_N	275_S	0.677	0.84
394_D	419_Y	0.676	0.84
356_N	360_E	0.675	0.84
88_A	103_F	0.672	0.84
295_A	299_G	0.671	0.84
161_A	165_V	0.670	0.84
300_T	303_I	0.669	0.84
47_R	51_V	0.667	0.83
186_L	189_T	0.662	0.83
250_M	303_I	0.661	0.83
71_E	94_Q	0.661	0.83
316_S	374_E	0.661	0.83
74_R	77_E	0.661	0.83
243_N	246_E	0.661	0.83
97_L	100_V	0.659	0.83
140_N	147_F	0.659	0.83
256_V	341_M	0.655	0.82
39_G	115_S	0.655	0.82
281_Q	458_S	0.653	0.82
423_V	446_I	0.652	0.82
121_A	124_D	0.650	0.82
371_L	374_E	0.647	0.82
406_G	410_Q	0.646	0.81
43_L	114_P	0.645	0.81
422_E	434_A	0.645	0.81
219_A	222_Q	0.644	0.81
89_E	129_R	0.643	0.81
261_L	403_R	0.642	0.81
225_D	441_Q	0.641	0.81
320_P	350_V	0.640	0.81
331_A	338_G	0.639	0.81
214_L	218_T	0.638	0.81
244_L	339_L	0.638	0.81
420_R	423_V	0.637	0.81
191_A	298_S	0.636	0.80
159_D	321_T	0.635	0.80
320_P	348_M	0.635	0.80
98_D	101_G	0.635	0.80
136_I	140_N	0.634	0.80
372_A	379_V	0.633	0.80
262_E	384_Q	0.633	0.80
43_L	116_A	0.633	0.80
349_R	363_E	0.631	0.80
427_N	431_K	0.631	0.80
75_L	86_T	0.627	0.80
327_A	371_L	0.626	0.79
237_K	343_D	0.625	0.79
346_Q	404_E	0.624	0.79
120_S	123_A	0.623	0.79
36_S	83_D	0.622	0.79
283_K	288_Q	0.621	0.79
44_D	47_R	0.621	0.79
331_A	375_L	0.621	0.79
213_D	449_V	0.620	0.79
135_M	165_V	0.620	0.79
108_E	112_N	0.619	0.79
141_E	144_E	0.619	0.79
250_M	276_L	0.617	0.78
213_D	463_Y	0.616	0.78
280_D	293_D	0.615	0.78
206_G	287_G	0.615	0.78
337_I	375_L	0.614	0.78
139_A	165_V	0.614	0.78
233_P	410_Q	0.613	0.78
135_M	139_A	0.613	0.78
221_L	380_V	0.611	0.78
79_G	349_R	0.610	0.78
235_M	402_L	0.610	0.78
33_A	85_I	0.608	0.77
84_L	106_L	0.608	0.77
366_R	370_A	0.605	0.77
204_V	208_N	0.604	0.77
114_P	126_V	0.601	0.77
244_L	380_V	0.601	0.77
263_M	442_R	0.600	0.76
51_V	54_R	0.599	0.76
127_R	171_S	0.598	0.76
383_S	407_S	0.598	0.76
56_V	73_A	0.596	0.76
295_A	298_S	0.595	0.76
272_S	310_I	0.595	0.76
48_W	82_I	0.594	0.76
141_E	160_L	0.593	0.76
68_I	109_L	0.593	0.76
131_V	154_S	0.591	0.75
232_R	410_Q	0.591	0.75
327_A	331_A	0.590	0.75
145_A	157_L	0.590	0.75
70_T	94_Q	0.589	0.75
421_D	430_L	0.589	0.75
42_M	72_M	0.589	0.75
436_I	449_V	0.588	0.75
347_L	366_R	0.588	0.75
419_Y	437_I	0.588	0.75
391_Q	398_V	0.585	0.75
91_L	97_L	0.585	0.75
55_V	69_F	0.585	0.75
61_Y	133_R	0.585	0.75
222_Q	441_Q	0.583	0.74
421_D	424_Y	0.583	0.74
422_E	425_H	0.583	0.74
389_L	419_Y	0.582	0.74
317_G	349_R	0.582	0.74
37_V	60_F	0.582	0.74
419_Y	423_V	0.581	0.74
40_G	122_Y	0.580	0.74
138_V	161_A	0.580	0.74
349_R	370_A	0.580	0.74
182_I	186_L	0.579	0.74
434_A	455_G	0.578	0.74
68_I	71_E	0.578	0.74
239_T	453_F	0.577	0.74
260_S	314_D	0.577	0.74
233_P	412_A	0.576	0.74
71_E	75_L	0.575	0.73
260_S	268_I	0.573	0.73
393_A	427_N	0.571	0.73
245_V	268_I	0.571	0.73
385_L	403_R	0.571	0.73
216_K	288_Q	0.571	0.73
278_R	454_N	0.570	0.73
91_L	101_G	0.568	0.73
227_I	380_V	0.567	0.72
103_F	108_E	0.566	0.72
320_P	368_L	0.566	0.72
218_T	222_Q	0.564	0.72
407_S	410_Q	0.563	0.72
211_Y	247_N	0.562	0.72
435_E	462_N	0.561	0.72
367_S	370_A	0.561	0.72
389_L	392_R	0.561	0.72
188_A	265_S	0.561	0.72
211_Y	240_F	0.559	0.71
98_D	102_G	0.554	0.71
340_I	371_L	0.554	0.71
43_L	113_T	0.553	0.71
241_A	380_V	0.552	0.70
233_P	385_L	0.552	0.70
363_E	367_S	0.552	0.70
230_A	402_L	0.550	0.70
320_P	371_L	0.549	0.70
402_L	415_I	0.549	0.70
349_R	366_R	0.547	0.70
419_Y	435_E	0.544	0.69
67_H	71_E	0.543	0.69
193_I	284_I	0.542	0.69
264_P	267_Q	0.542	0.69
105_Y	109_L	0.541	0.69
193_I	196_L	0.540	0.69
51_V	69_F	0.540	0.69
358_T	373_K	0.538	0.68
49_D	332_R	0.538	0.68
184_D	188_A	0.538	0.68
289_L	293_D	0.537	0.68
224_S	373_K	0.536	0.68
233_P	402_L	0.536	0.68
273_L	301_M	0.536	0.68
438_I	441_Q	0.535	0.68
344_Y	361_I	0.534	0.68
143_A	146_G	0.534	0.68
237_K	262_E	0.533	0.68
142_I	165_V	0.533	0.68
315_S	326_R	0.532	0.68
185_V	188_A	0.531	0.67
138_V	142_I	0.528	0.67
317_G	370_A	0.528	0.67
452_T	464_A	0.527	0.67
402_L	417_F	0.526	0.67
416_M	438_I	0.526	0.67
36_S	85_I	0.526	0.67
230_A	389_L	0.525	0.67
325_S	329_R	0.524	0.66
222_Q	443_N	0.522	0.66
441_Q	449_V	0.522	0.66
441_Q	447_G	0.521	0.66
25_K	140_N	0.520	0.66
423_V	434_A	0.520	0.66
86_T	125_I	0.519	0.66
423_V	436_I	0.518	0.66
409_E	412_A	0.518	0.66
142_I	146_G	0.517	0.65
402_L	406_G	0.517	0.65
366_R	411_D	0.517	0.65
309_N	334_H	0.517	0.65
451_L	462_N	0.517	0.65
361_I	365_S	0.516	0.65
81_P	86_T	0.516	0.65
415_I	439_G	0.515	0.65
65_H	68_I	0.514	0.65
196_L	287_G	0.514	0.65
232_R	406_G	0.513	0.65
187_D	306_E	0.513	0.65
44_D	50_D	0.511	0.65
396_R	419_Y	0.511	0.65
301_M	306_E	0.510	0.64
229_V	436_I	0.510	0.64
41_L	69_F	0.510	0.64
225_D	234_S	0.509	0.64
246_E	308_R	0.509	0.64
71_E	91_L	0.507	0.64
132_V	154_S	0.507	0.64
222_Q	234_S	0.507	0.64
353_L	356_N	0.507	0.64
337_I	377_V	0.507	0.64
72_M	114_P	0.507	0.64
158_L	164_R	0.506	0.64
259_F	326_R	0.506	0.64
331_A	334_H	0.505	0.64
430_L	435_E	0.505	0.64
394_D	424_Y	0.504	0.63
334_H	337_I	0.503	0.63
79_G	82_I	0.503	0.63
217_K	445_P	0.502	0.63
72_M	87_L	0.502	0.63
234_S	423_V	0.502	0.63
340_I	379_V	0.502	0.63
426_E	431_K	0.502	0.63
262_E	442_R	0.502	0.63
166_F	169_A	0.502	0.63
247_N	451_L	0.502	0.63
143_A	147_F	0.501	0.63
79_G	416_M	0.501	0.63
347_L	385_L	0.501	0.63
209_T	380_V	0.500	0.63
190_V	301_M	0.500	0.63

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2q6tA	1	0.8981	100	0.235	Contact Map
4nmnA	3	0.9066	100	0.236	Contact Map
3bgwA	3	0.8832	100	0.244	Contact Map
2r6aA	5	0.8917	100	0.273	Contact Map
4a1fA	2	0.6115	100	0.527	Contact Map
3bh0A	1	0.5945	100	0.536	Contact Map
1cr0A	3	0.4968	100	0.606	Contact Map
1q57A	3	0.9087	100	0.618	Contact Map
3io5A	2	0.4098	100	0.687	Contact Map
1nlfA	3	0.4947	100	0.709	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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