GNTU - ECOLI - GREMLIN Contacts

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GNTU - Low-affinity gluconate transporter

UniProt:	P0AC96	Sequences: MTTLTLVLTAVGSVLLLLFLVMKARMHAFLALMVVSMGAGLFSGMPLDKIAATMEKGMGGTLGFLAVVVALGAMFGKILHETGAVDQIAVKMLKSFGHSRAHYAIGLAGLVCALPLFFEVAIVLLISVAFSMARHTGTNLVKLVIPLFAGVAAAAAFLVPGPAPMLLASQMNADFGWMILIGLCAAIPGMIIAGPLWGNFISRYVELHIPDDISEPHLGEGKMPSFGFSLSLILLPLVLVGLKTIAARFVPEGSTAYEWFEFIGHPFTAILVACLVAIYGLAMRQGMPKDKVMEICGHALQPAGIILLVIGAGGVFKQVLVDSGVGPALGEALTGMGLPIAITCFVLAAAVRIIQGSATVACLTAVGLVMPVIEQLNYSGAQMAALSICIAGGSIVVSHVNDAGFWLFGKFTGATEAETLKTWTMMETILGTVGAIVGMIAFQLLS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12631
Length:	446 (420)
Sequences:	4928 (3205)
Seq/√Len:	156.4

ECOLI - GNTU GNTP YJHF YGBN IDNT GNTT DSDX
BACSU - YOJA GNTP YXJC
HALSA - Q9HNF6 Q9HNR2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
235_L	276_V	3.808	1.00
16_L	38_G	3.520	1.00
184_C	188_P	3.472	1.00
13_S	316_F	3.468	1.00
318_Q	322_D	3.214	1.00
91_K	226_F	3.209	1.00
13_S	39_A	3.176	1.00
298_H	301_Q	3.153	1.00
232_L	236_P	3.136	1.00
91_K	95_S	3.080	1.00
327_P	331_E	3.064	1.00
53_T	322_D	3.049	1.00
81_E	295_I	2.927	1.00
288_P	291_K	2.915	1.00
342_I	435_A	2.903	1.00
15_L	19_F	2.821	1.00
415_T	418_E	2.818	1.00
226_F	230_L	2.602	1.00
349_A	396_V	2.597	1.00
175_F	179_I	2.543	1.00
345_F	431_G	2.542	1.00
236_P	240_V	2.501	1.00
91_K	94_K	2.460	1.00
52_A	56_K	2.412	1.00
331_E	334_T	2.387	1.00
86_D	90_V	2.343	1.00
171_M	390_I	2.263	1.00
46_P	49_K	2.255	1.00
19_F	23_K	2.253	1.00
436_I	440_I	2.222	1.00
200_F	204_Y	2.197	1.00
180_L	184_C	2.188	1.00
192_I	196_L	2.180	1.00
182_G	185_A	2.156	1.00
197_W	201_I	2.156	1.00
428_T	432_T	2.141	1.00
432_T	436_I	2.136	1.00
229_S	232_L	2.136	1.00
175_F	180_L	2.132	1.00
46_P	50_I	2.111	1.00
56_K	60_G	2.101	1.00
348_A	365_A	2.062	1.00
186_A	189_G	2.049	1.00
16_L	35_V	2.047	1.00
353_I	397_V	2.018	1.00
225_S	228_F	1.988	1.00
344_C	390_I	1.959	1.00
328_A	332_A	1.926	1.00
266_P	270_I	1.918	1.00
229_S	236_P	1.901	1.00
167_L	362_C	1.898	1.00
232_L	240_V	1.885	1.00
49_K	52_A	1.867	1.00
103_Y	195_P	1.863	1.00
239_L	243_K	1.851	1.00
425_M	429_I	1.840	1.00
181_I	184_C	1.837	1.00
421_K	425_M	1.830	1.00
98_H	135_H	1.806	1.00
9_T	42_F	1.773	1.00
227_G	231_S	1.762	1.00
185_A	441_A	1.761	1.00
176_G	179_I	1.751	1.00
78_I	277_A	1.730	1.00
276_V	280_G	1.730	1.00
204_Y	208_H	1.727	1.00
17_L	35_V	1.721	1.00
74_M	296_C	1.717	1.00
317_K	321_V	1.703	1.00
182_G	188_P	1.691	1.00
170_Q	366_V	1.688	1.00
178_M	387_S	1.672	1.00
174_D	177_W	1.665	1.00
205_V	209_I	1.664	1.00
279_Y	284_R	1.635	1.00
196_L	200_F	1.621	1.00
87_Q	91_K	1.620	1.00
119_E	403_A	1.613	1.00
180_L	183_L	1.605	1.00
208_H	211_D	1.601	1.00
206_E	209_I	1.597	1.00
239_L	272_V	1.586	1.00
156_A	395_I	1.584	1.00
58_M	66_A	1.582	1.00
228_F	232_L	1.580	1.00
233_I	236_P	1.568	1.00
203_R	207_L	1.562	1.00
398_S	402_D	1.561	1.00
77_K	81_E	1.557	1.00
409_G	419_T	1.549	1.00
16_L	20_L	1.545	1.00
38_G	42_F	1.544	1.00
392_G	438_G	1.534	1.00
439_M	442_F	1.522	1.00
396_V	431_G	1.521	1.00
144_V	412_T	1.498	1.00
196_L	199_N	1.476	1.00
392_G	434_G	1.465	1.00
119_E	310_I	1.462	1.00
176_G	180_L	1.453	1.00
137_G	208_H	1.445	1.00
275_L	279_Y	1.441	1.00
433_V	437_V	1.431	1.00
227_G	232_L	1.430	1.00
26_M	31_A	1.427	1.00
85_V	89_A	1.425	1.00
118_F	404_G	1.406	1.00
106_G	190_M	1.405	1.00
183_L	186_A	1.394	1.00
57_G	318_Q	1.393	1.00
397_V	424_T	1.392	1.00
294_E	298_H	1.386	1.00
379_S	384_A	1.381	1.00
231_S	235_L	1.371	1.00
437_V	441_A	1.371	1.00
409_G	416_E	1.363	1.00
179_I	184_C	1.356	1.00
232_L	248_R	1.354	1.00
236_P	248_R	1.344	1.00
82_T	281_L	1.341	1.00
227_G	236_P	1.341	1.00
202_S	206_E	1.335	1.00
396_V	428_T	1.334	1.00
201_I	204_Y	1.323	1.00
81_E	291_K	1.321	1.00
54_M	315_V	1.312	1.00
184_C	189_G	1.311	1.00
174_D	179_I	1.309	1.00
177_W	180_L	1.299	1.00
228_F	231_S	1.285	1.00
53_T	318_Q	1.282	1.00
290_D	294_E	1.271	1.00
134_R	140_L	1.263	1.00
201_I	205_V	1.250	1.00
194_G	198_G	1.242	1.00
122_I	411_F	1.242	1.00
257_Y	260_F	1.240	1.00
233_I	240_V	1.239	1.00
224_P	229_S	1.230	1.00
353_I	396_V	1.229	1.00
379_S	383_M	1.225	1.00
278_I	296_C	1.223	1.00
324_G	327_P	1.213	1.00
310_I	403_A	1.200	1.00
398_S	423_W	1.199	1.00
182_G	186_A	1.194	1.00
179_I	182_G	1.194	1.00
188_P	192_I	1.187	1.00
266_P	269_A	1.186	1.00
246_A	250_V	1.184	1.00
199_N	203_R	1.183	1.00
202_S	205_V	1.172	1.00
418_E	421_K	1.170	1.00
185_A	189_G	1.167	1.00
183_L	187_I	1.165	1.00
185_A	188_P	1.157	1.00
109_G	112_C	1.156	1.00
90_V	135_H	1.151	1.00
45_M	53_T	1.150	1.00
175_F	184_C	1.147	1.00
197_W	200_F	1.139	1.00
357_S	360_V	1.133	1.00
13_S	38_G	1.131	1.00
108_A	112_C	1.127	1.00
10_A	14_V	1.121	1.00
105_I	109_G	1.120	1.00
197_W	425_M	1.116	1.00
154_A	161_G	1.113	1.00
352_R	402_D	1.106	1.00
185_A	437_V	1.106	1.00
370_M	374_E	1.103	0.99
273_A	277_A	1.101	0.99
77_K	295_I	1.092	0.99
48_D	52_A	1.090	0.99
182_G	189_G	1.087	0.99
86_D	221_G	1.080	0.99
120_V	123_V	1.080	0.99
166_L	363_L	1.079	0.99
209_I	212_D	1.077	0.99
90_V	94_K	1.077	0.99
149_A	194_G	1.075	0.99
247_A	261_E	1.074	0.99
43_S	323_S	1.073	0.99
152_A	427_E	1.072	0.99
291_K	294_E	1.070	0.99
417_A	421_K	1.067	0.99
257_Y	261_E	1.066	0.99
204_Y	207_L	1.059	0.99
175_F	178_M	1.053	0.99
236_P	247_A	1.051	0.99
164_P	168_A	1.050	0.99
61_T	314_G	1.048	0.99
206_E	210_P	1.047	0.99
31_A	35_V	1.047	0.99
51_A	55_E	1.042	0.99
39_A	316_F	1.040	0.99
195_P	198_G	1.040	0.99
239_L	276_V	1.039	0.99
84_A	229_S	1.037	0.99
192_I	433_V	1.036	0.99
318_Q	321_V	1.032	0.99
361_A	402_D	1.031	0.99
56_K	59_G	1.029	0.99
183_L	188_P	1.020	0.99
73_A	296_C	1.015	0.99
397_V	401_N	1.012	0.99
218_L	222_K	1.008	0.99
165_M	168_A	1.004	0.99
427_E	430_L	1.003	0.99
225_S	229_S	1.003	0.99
203_R	206_E	1.002	0.99
240_V	244_T	1.000	0.99
439_M	443_Q	0.999	0.99
7_V	11_V	0.999	0.99
173_A	178_M	0.997	0.99
426_M	430_L	0.991	0.99
145_I	149_A	0.989	0.99
220_E	223_M	0.988	0.99
229_S	233_I	0.987	0.99
303_A	307_L	0.987	0.99
49_K	53_T	0.979	0.99
35_V	38_G	0.977	0.99
29_F	308_L	0.976	0.99
419_T	423_W	0.974	0.99
107_L	111_V	0.971	0.99
194_G	199_N	0.967	0.99
88_I	229_S	0.961	0.99
218_L	221_G	0.959	0.99
52_A	55_E	0.951	0.98
434_G	438_G	0.950	0.98
229_S	240_V	0.948	0.98
228_F	236_P	0.947	0.98
345_F	435_A	0.945	0.98
243_K	247_A	0.939	0.98
435_A	439_M	0.938	0.98
120_V	163_A	0.937	0.98
219_G	222_K	0.936	0.98
340_I	376_L	0.934	0.98
349_A	353_I	0.929	0.98
194_G	197_W	0.927	0.98
138_T	142_K	0.926	0.98
20_L	34_V	0.926	0.98
194_G	200_F	0.925	0.98
383_M	386_L	0.924	0.98
112_C	125_L	0.921	0.98
205_V	208_H	0.917	0.98
207_L	210_P	0.917	0.98
192_I	200_F	0.915	0.98
440_I	443_Q	0.915	0.98
262_F	265_H	0.914	0.98
398_S	401_N	0.911	0.98
235_L	273_A	0.910	0.98
201_I	429_I	0.908	0.98
258_E	261_E	0.907	0.98
342_I	439_M	0.906	0.98
358_A	394_S	0.904	0.98
154_A	158_L	0.901	0.98
179_I	183_L	0.900	0.98
373_I	385_A	0.897	0.98
219_G	223_M	0.897	0.98
37_M	268_T	0.896	0.98
195_P	199_N	0.895	0.98
236_P	244_T	0.892	0.98
100_R	104_A	0.892	0.98
186_A	190_M	0.890	0.98
374_E	383_M	0.889	0.98
43_S	46_P	0.889	0.98
332_A	336_M	0.888	0.98
20_L	31_A	0.888	0.98
149_A	426_M	0.884	0.98
203_R	209_I	0.883	0.98
9_T	43_S	0.878	0.97
226_F	233_I	0.878	0.97
388_I	438_G	0.878	0.97
39_A	319_V	0.876	0.97
352_R	398_S	0.875	0.97
113_A	154_A	0.873	0.97
358_A	403_A	0.869	0.97
181_I	384_A	0.867	0.97
90_V	223_M	0.862	0.97
118_F	121_A	0.857	0.97
45_M	323_S	0.856	0.97
203_R	208_H	0.855	0.97
110_L	114_L	0.853	0.97
175_F	183_L	0.853	0.97
203_R	211_D	0.851	0.97
371_P	375_Q	0.850	0.97
153_A	186_A	0.844	0.97
178_M	384_A	0.842	0.97
57_G	60_G	0.840	0.97
179_I	188_P	0.840	0.97
333_L	347_L	0.838	0.97
14_V	17_L	0.836	0.97
244_T	247_A	0.830	0.96
204_Y	211_D	0.830	0.96
397_V	420_L	0.827	0.96
229_S	248_R	0.825	0.96
228_F	280_G	0.825	0.96
178_M	181_I	0.822	0.96
81_E	298_H	0.820	0.96
279_Y	283_M	0.820	0.96
41_L	47_L	0.819	0.96
67_V	71_L	0.819	0.96
166_L	170_Q	0.818	0.96
92_M	96_F	0.817	0.96
30_L	274_C	0.816	0.96
87_Q	223_M	0.815	0.96
278_I	292_V	0.810	0.96
202_S	208_H	0.807	0.96
12_G	16_L	0.806	0.96
133_A	138_T	0.804	0.96
245_I	249_F	0.795	0.95
98_H	136_T	0.795	0.95
87_Q	226_F	0.794	0.95
226_F	232_L	0.793	0.95
232_L	280_G	0.791	0.95
329_L	333_L	0.788	0.95
245_I	248_R	0.787	0.95
157_F	434_G	0.787	0.95
360_V	364_T	0.785	0.95
9_T	13_S	0.784	0.95
260_F	265_H	0.783	0.95
278_I	282_A	0.782	0.95
400_V	420_L	0.782	0.95
129_A	147_L	0.781	0.95
234_L	238_V	0.780	0.95
344_C	386_L	0.779	0.95
338_L	342_I	0.778	0.95
106_G	110_L	0.778	0.95
362_C	394_S	0.778	0.95
95_S	99_S	0.777	0.95
247_A	250_V	0.776	0.95
152_A	395_I	0.770	0.95
200_F	203_R	0.767	0.94
147_L	150_G	0.766	0.94
333_L	336_M	0.765	0.94
362_C	365_A	0.765	0.94
197_W	429_I	0.764	0.94
287_M	292_V	0.764	0.94
121_A	161_G	0.764	0.94
102_H	105_I	0.763	0.94
147_L	412_T	0.762	0.94
142_K	146_P	0.762	0.94
11_V	15_L	0.760	0.94
388_I	392_G	0.760	0.94
424_T	431_G	0.760	0.94
53_T	56_K	0.758	0.94
240_V	248_R	0.755	0.94
181_I	187_I	0.754	0.94
148_F	405_F	0.750	0.94
355_Q	360_V	0.745	0.94
79_L	84_A	0.745	0.94
208_H	212_D	0.745	0.94
180_L	188_P	0.744	0.94
202_S	207_L	0.742	0.93
344_C	348_A	0.742	0.93
326_G	330_G	0.741	0.93
99_S	212_D	0.739	0.93
422_T	425_M	0.739	0.93
178_M	182_G	0.737	0.93
139_N	202_S	0.727	0.93
352_R	358_A	0.727	0.93
175_F	186_A	0.727	0.93
170_Q	367_G	0.725	0.93
45_M	50_I	0.724	0.93
341_A	378_Y	0.724	0.93
177_W	183_L	0.724	0.93
71_L	162_P	0.724	0.93
20_L	26_M	0.723	0.93
297_G	301_Q	0.722	0.93
358_A	398_S	0.722	0.93
329_L	354_I	0.722	0.93
268_T	272_V	0.721	0.92
343_T	373_I	0.721	0.92
183_L	189_G	0.720	0.92
54_M	60_G	0.718	0.92
114_L	154_A	0.717	0.92
110_L	153_A	0.716	0.92
319_V	322_D	0.711	0.92
259_W	263_I	0.710	0.92
373_I	386_L	0.710	0.92
371_P	376_L	0.709	0.92
250_V	257_Y	0.708	0.92
341_A	443_Q	0.702	0.91
141_V	207_L	0.701	0.91
213_I	217_H	0.700	0.91
430_L	434_G	0.700	0.91
224_P	232_L	0.700	0.91
11_V	436_I	0.698	0.91
121_A	125_L	0.696	0.91
156_A	167_L	0.694	0.91
175_F	182_G	0.693	0.91
226_F	229_S	0.693	0.91
225_S	232_L	0.692	0.91
116_L	123_V	0.691	0.91
198_G	202_S	0.689	0.91
280_G	284_R	0.688	0.91
222_K	291_K	0.687	0.91
395_I	398_S	0.686	0.91
77_K	298_H	0.685	0.90
189_G	433_V	0.681	0.90
84_A	87_Q	0.680	0.90
33_M	71_L	0.678	0.90
414_A	418_E	0.678	0.90
38_G	41_L	0.678	0.90
437_V	440_I	0.677	0.90
270_I	273_A	0.676	0.90
122_I	126_I	0.673	0.90
236_P	241_G	0.672	0.90
193_A	197_W	0.672	0.90
11_V	35_V	0.672	0.90
416_E	420_L	0.670	0.89
433_V	436_I	0.668	0.89
184_C	192_I	0.667	0.89
74_M	273_A	0.666	0.89
155_A	161_G	0.666	0.89
139_N	205_V	0.664	0.89
192_I	198_G	0.664	0.89
399_H	427_E	0.663	0.89
54_M	312_A	0.662	0.89
94_K	203_R	0.662	0.89
121_A	151_V	0.662	0.89
232_L	284_R	0.659	0.89
361_A	365_A	0.657	0.89
9_T	35_V	0.657	0.89
246_A	260_F	0.656	0.88
95_S	279_Y	0.654	0.88
397_V	428_T	0.651	0.88
56_K	322_D	0.650	0.88
309_V	363_L	0.649	0.88
181_I	388_I	0.648	0.88
45_M	49_K	0.648	0.88
355_Q	361_A	0.647	0.88
175_F	188_P	0.646	0.88
152_A	394_S	0.643	0.87
423_W	427_E	0.641	0.87
222_K	228_F	0.641	0.87
226_F	231_S	0.639	0.87
192_I	195_P	0.639	0.87
228_F	276_V	0.638	0.87
397_V	402_D	0.638	0.87
150_G	154_A	0.637	0.87
97_G	100_R	0.637	0.87
361_A	398_S	0.635	0.87
172_N	331_E	0.634	0.87
16_L	19_F	0.633	0.87
17_L	31_A	0.631	0.86
227_G	230_L	0.629	0.86
140_L	144_V	0.629	0.86
113_A	116_L	0.628	0.86
116_L	270_I	0.628	0.86
71_L	404_G	0.628	0.86
9_T	12_G	0.627	0.86
179_I	186_A	0.627	0.86
399_H	422_T	0.626	0.86
36_S	312_A	0.624	0.86
195_P	200_F	0.623	0.86
177_W	181_I	0.621	0.86
153_A	156_A	0.620	0.86
51_A	268_T	0.619	0.85
399_H	406_W	0.619	0.85
246_A	257_Y	0.618	0.85
77_K	80_H	0.617	0.85
205_V	210_P	0.615	0.85
40_G	50_I	0.614	0.85
34_V	38_G	0.611	0.85
142_K	202_S	0.611	0.85
420_L	424_T	0.611	0.85
205_V	212_D	0.611	0.85
241_G	245_I	0.609	0.84
62_L	311_G	0.608	0.84
177_W	384_A	0.608	0.84
27_H	30_L	0.607	0.84
110_L	154_A	0.607	0.84
25_R	134_R	0.606	0.84
56_K	318_Q	0.606	0.84
261_E	264_G	0.605	0.84
228_F	240_V	0.605	0.84
105_I	108_A	0.605	0.84
149_A	153_A	0.603	0.84
174_D	178_M	0.602	0.84
158_L	161_G	0.602	0.84
113_A	161_G	0.602	0.84
15_L	284_R	0.602	0.84
236_P	250_V	0.601	0.84
36_S	315_V	0.600	0.84
73_A	194_G	0.600	0.84
31_A	37_M	0.598	0.83
199_N	202_S	0.597	0.83
157_F	183_L	0.597	0.83
385_A	442_F	0.596	0.83
349_A	431_G	0.595	0.83
339_P	342_I	0.593	0.83
202_S	209_I	0.593	0.83
9_T	39_A	0.591	0.83
119_E	123_V	0.590	0.83
145_I	426_M	0.590	0.83
178_M	184_C	0.590	0.83
352_R	361_A	0.589	0.82
9_T	38_G	0.585	0.82
126_I	412_T	0.585	0.82
176_G	182_G	0.585	0.82
365_A	390_I	0.584	0.82
348_A	394_S	0.584	0.82
357_S	361_A	0.583	0.82
87_Q	225_S	0.583	0.82
13_S	43_S	0.579	0.81
398_S	427_E	0.575	0.81
74_M	292_V	0.575	0.81
237_L	241_G	0.574	0.81
356_G	361_A	0.574	0.81
277_A	280_G	0.574	0.81
225_S	233_I	0.573	0.81
281_L	284_R	0.573	0.81
119_E	162_P	0.572	0.81
389_C	393_G	0.572	0.81
161_G	310_I	0.571	0.81
90_V	219_G	0.571	0.81
207_L	418_E	0.570	0.80
226_F	240_V	0.570	0.80
201_I	211_D	0.569	0.80
378_Y	383_M	0.569	0.80
227_G	249_F	0.568	0.80
39_A	325_V	0.568	0.80
344_C	369_V	0.568	0.80
50_I	54_M	0.568	0.80
358_A	395_I	0.565	0.80
181_I	185_A	0.565	0.80
406_W	419_T	0.565	0.80
155_A	359_T	0.564	0.80
116_L	317_K	0.564	0.80
86_D	108_A	0.564	0.80
373_I	377_N	0.563	0.80
408_F	414_A	0.563	0.80
148_F	404_G	0.562	0.79
328_A	331_E	0.562	0.79
105_I	112_C	0.561	0.79
385_A	441_A	0.561	0.79
79_L	164_P	0.560	0.79
202_S	430_L	0.560	0.79
148_F	426_M	0.559	0.79
16_L	23_K	0.559	0.79
196_L	204_Y	0.558	0.79
170_Q	351_V	0.558	0.79
84_A	281_L	0.558	0.79
185_A	438_G	0.557	0.79
153_A	427_E	0.557	0.79
235_L	240_V	0.556	0.79
109_G	125_L	0.551	0.78
164_P	167_L	0.551	0.78
130_F	140_L	0.550	0.78
17_L	354_I	0.550	0.78
357_S	405_F	0.550	0.78
12_G	38_G	0.549	0.78
263_I	268_T	0.548	0.78
201_I	208_H	0.548	0.78
231_S	238_V	0.547	0.78
122_I	159_V	0.547	0.78
226_F	236_P	0.547	0.78
156_A	392_G	0.546	0.78
193_A	196_L	0.545	0.77
259_W	265_H	0.545	0.77
294_E	297_G	0.544	0.77
154_A	164_P	0.542	0.77
142_K	153_A	0.542	0.77
8_L	12_G	0.541	0.77
284_R	288_P	0.540	0.77
97_G	104_A	0.540	0.77
58_M	67_V	0.539	0.77
171_M	174_D	0.537	0.76
227_G	233_I	0.537	0.76
70_A	308_L	0.537	0.76
438_G	442_F	0.537	0.76
218_L	225_S	0.537	0.76
56_K	327_P	0.536	0.76
73_A	278_I	0.536	0.76
422_T	426_M	0.534	0.76
232_L	235_L	0.533	0.76
293_M	296_C	0.533	0.76
105_I	143_L	0.533	0.76
231_S	280_G	0.532	0.76
188_P	437_V	0.532	0.76
402_D	423_W	0.529	0.75
152_A	358_A	0.528	0.75
347_L	368_L	0.528	0.75
269_A	274_C	0.526	0.75
189_G	437_V	0.525	0.75
113_A	150_G	0.525	0.75
193_A	198_G	0.524	0.75
283_M	291_K	0.524	0.75
402_D	405_F	0.524	0.75
29_F	33_M	0.523	0.74
36_S	40_G	0.522	0.74
79_L	281_L	0.522	0.74
153_A	430_L	0.521	0.74
227_G	234_L	0.521	0.74
58_M	62_L	0.521	0.74
157_F	392_G	0.520	0.74
55_E	64_F	0.519	0.74
16_L	374_E	0.518	0.74
53_T	57_G	0.517	0.74
50_I	319_V	0.517	0.74
263_I	267_F	0.516	0.74
17_L	21_V	0.515	0.73
338_L	440_I	0.515	0.73
93_L	136_T	0.514	0.73
131_S	329_L	0.514	0.73
281_L	292_V	0.513	0.73
161_G	164_P	0.513	0.73
161_G	362_C	0.512	0.73
242_L	246_A	0.512	0.73
213_I	222_K	0.512	0.73
87_Q	229_S	0.512	0.73
10_A	325_V	0.512	0.73
377_N	383_M	0.512	0.73
353_I	424_T	0.512	0.73
351_V	395_I	0.510	0.73
39_A	42_F	0.509	0.73
291_K	295_I	0.509	0.73
372_V	376_L	0.508	0.72
348_A	361_A	0.508	0.72
355_Q	398_S	0.506	0.72
25_R	31_A	0.505	0.72
274_C	278_I	0.504	0.72
278_I	281_L	0.504	0.72
185_A	388_I	0.504	0.72
121_A	391_A	0.503	0.72
156_A	358_A	0.502	0.71
414_A	419_T	0.502	0.71
49_K	331_E	0.500	0.71

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4r1iA	2	0.9709	100	0.606	Contact Map
4r0cA	3	0.9664	100	0.619	Contact Map
4f35D	2	0.8924	100	0.66	Contact Map
4pd6A	3	0.7556	63.2	0.952	Contact Map
4dx5A	3	0.3632	59.7	0.953	Contact Map
2a65A	2	0.5605	49.3	0.956	Contact Map
2cfqA	1	0.8117	49.1	0.956	Contact Map
3qe7A	2	0.4484	41.3	0.958	Contact Map
3giaA	1	0.4484	36.9	0.959	Contact Map
3aqpA	1	0.3363	33.3	0.96	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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