GNTP - ECOLI - GREMLIN Contacts

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GNTP - High-affinity gluconate transporter

UniProt:	P0AC94	Sequences: MHVLNILWVVFGIGLMLVLNLKFKINSMVALLVAALSVGMLAGMDLMSLLHTMKAGFGNTLGELAIIVVFGAVIGKLMVDSGAAHQIAHTLLARLGLRYVQLSVIIIGLIFGLAMFYEVAFIMLAPLVIVIAAEAKIPFLKLAIPAVAAATTAHSLFPPQPGPVALVNAYGADMGMVYIYGVLVTIPSVICAGLILPKFLGNLERPTPSFLKADQPVDMNNLPSFGVSILVPLIPAIIMISTTIANIWLVKDTPAWEVVNFIGSSPIAMFIAMVVAFVLFGTARGHDMQWVMNAFESAVKSIAMVILIIGAGGVLKQTIIDTGIGDTIGMLMSHGNISPYIMAWLITVLIRLATGQGVVSAMTAAGIISAAILDPATGQLVGVNPALLVLATAAGSNTLTHINDASFWLFKGYFDLSVKDTLKTWGLLELVNSVVGLIIVLIISMVA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12563
Length:	447 (424)
Sequences:	4538 (3036)
Seq/√Len:	147.4

ECOLI - GNTP GNTU YJHF YGBN GNTT IDNT DSDX
BACSU - YOJA GNTP YXJC
HALSA - Q9HNF6 Q9HNR2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
203_L	207_T	3.588	1.00
234_I	275_V	3.496	1.00
231_V	235_P	3.233	1.00
178_Y	181_G	3.206	1.00
90_T	225_F	3.025	1.00
12_G	38_V	2.865	1.00
183_L	187_P	2.827	1.00
52_T	321_D	2.812	1.00
203_L	206_P	2.752	1.00
317_Q	321_D	2.741	1.00
12_G	315_L	2.741	1.00
15_L	37_S	2.728	1.00
228_S	231_V	2.685	1.00
326_D	330_M	2.580	1.00
193_G	197_P	2.576	1.00
265_S	269_M	2.562	1.00
287_D	290_W	2.474	1.00
225_F	229_I	2.418	1.00
235_P	239_M	2.408	1.00
228_S	235_P	2.399	1.00
231_V	239_M	2.393	1.00
90_T	94_R	2.386	1.00
344_W	433_S	2.356	1.00
178_Y	182_V	2.346	1.00
417_S	420_D	2.340	1.00
297_S	300_K	2.338	1.00
174_M	178_Y	2.286	1.00
80_D	294_A	2.282	1.00
45_D	48_S	2.281	1.00
185_T	188_S	2.270	1.00
14_G	18_V	2.266	1.00
18_V	22_K	2.264	1.00
55_A	59_N	2.239	1.00
196_L	200_L	2.212	1.00
180_Y	183_L	2.159	1.00
173_D	176_M	2.135	1.00
90_T	93_A	2.109	1.00
198_K	202_N	2.079	1.00
51_H	55_A	2.051	1.00
224_S	227_V	2.049	1.00
180_Y	184_V	2.040	1.00
256_W	260_N	2.029	1.00
204_E	207_T	2.024	1.00
176_M	180_Y	2.009	1.00
15_L	34_A	1.963	1.00
199_F	202_N	1.963	1.00
48_S	51_H	1.943	1.00
348_V	398_T	1.943	1.00
175_G	180_Y	1.941	1.00
175_G	178_Y	1.929	1.00
170_Y	392_T	1.921	1.00
45_D	49_L	1.869	1.00
179_I	182_V	1.855	1.00
438_I	442_I	1.842	1.00
330_M	333_S	1.836	1.00
223_P	228_S	1.797	1.00
179_I	183_L	1.785	1.00
352_L	399_L	1.779	1.00
227_V	231_V	1.779	1.00
85_H	89_H	1.776	1.00
176_M	179_I	1.757	1.00
341_I	437_L	1.749	1.00
238_I	271_I	1.739	1.00
200_L	203_L	1.729	1.00
343_A	392_T	1.721	1.00
430_L	434_V	1.711	1.00
196_L	199_F	1.695	1.00
166_L	361_A	1.694	1.00
275_V	279_L	1.687	1.00
335_G	340_Y	1.681	1.00
423_K	427_L	1.677	1.00
327_T	331_L	1.674	1.00
258_V	261_F	1.656	1.00
186_I	190_I	1.650	1.00
204_E	208_P	1.639	1.00
181_G	184_V	1.635	1.00
20_N	24_K	1.631	1.00
434_V	438_I	1.628	1.00
172_A	177_V	1.626	1.00
226_G	230_L	1.612	1.00
97_L	134_E	1.597	1.00
195_I	199_F	1.594	1.00
347_T	364_A	1.592	1.00
178_Y	183_L	1.591	1.00
382_G	385_P	1.581	1.00
258_V	262_I	1.576	1.00
177_V	389_V	1.569	1.00
205_R	208_P	1.557	1.00
15_L	19_L	1.528	1.00
118_E	405_A	1.519	1.00
274_V	278_V	1.507	1.00
25_I	30_A	1.500	1.00
177_V	180_Y	1.498	1.00
191_C	435_V	1.490	1.00
184_V	188_S	1.483	1.00
427_L	431_V	1.476	1.00
14_G	17_L	1.467	1.00
178_Y	185_T	1.456	1.00
197_P	200_L	1.449	1.00
185_T	189_V	1.441	1.00
169_A	365_A	1.440	1.00
228_S	239_M	1.438	1.00
336_N	339_P	1.436	1.00
173_D	178_Y	1.431	1.00
247_I	250_V	1.424	1.00
175_G	179_I	1.416	1.00
225_F	228_S	1.413	1.00
56_G	317_Q	1.410	1.00
316_K	320_I	1.403	1.00
224_S	228_S	1.396	1.00
227_V	235_P	1.391	1.00
228_S	232_P	1.391	1.00
226_G	235_P	1.384	1.00
155_S	397_N	1.379	1.00
176_M	182_V	1.377	1.00
256_W	259_V	1.371	1.00
108_G	111_F	1.370	1.00
411_K	421_T	1.370	1.00
193_G	196_L	1.367	1.00
178_Y	184_V	1.364	1.00
256_W	261_F	1.364	1.00
232_P	239_M	1.354	1.00
232_P	235_P	1.354	1.00
398_T	433_S	1.350	1.00
178_Y	187_P	1.346	1.00
183_L	186_I	1.344	1.00
118_E	309_I	1.342	1.00
143_A	414_F	1.341	1.00
180_Y	186_I	1.339	1.00
37_S	41_L	1.332	1.00
242_T	246_N	1.323	1.00
8_W	41_L	1.320	1.00
399_L	426_G	1.309	1.00
264_S	269_M	1.306	1.00
172_A	176_M	1.290	1.00
117_Y	406_S	1.284	1.00
180_Y	185_T	1.278	1.00
309_I	405_A	1.277	1.00
173_D	182_V	1.276	1.00
173_D	177_V	1.272	1.00
77_L	276_A	1.269	1.00
179_I	184_V	1.268	1.00
76_K	80_D	1.268	1.00
223_P	231_V	1.267	1.00
372_I	388_L	1.256	1.00
184_V	187_P	1.254	1.00
225_F	235_P	1.254	1.00
381_V	385_P	1.253	1.00
223_P	235_P	1.249	1.00
119_V	122_I	1.245	1.00
195_I	198_K	1.234	1.00
181_G	187_P	1.221	1.00
85_H	220_N	1.218	1.00
87_I	228_S	1.215	1.00
182_V	186_I	1.214	1.00
441_L	444_S	1.214	1.00
289_Q	293_N	1.211	1.00
244_I	247_I	1.203	1.00
394_A	436_G	1.199	1.00
184_V	443_I	1.191	1.00
174_M	181_G	1.190	1.00
198_K	201_G	1.188	1.00
181_G	185_T	1.186	1.00
177_V	181_G	1.185	1.00
86_Q	90_T	1.185	1.00
227_V	239_M	1.178	1.00
199_F	203_L	1.176	1.00
400_T	404_D	1.176	1.00
14_G	22_K	1.173	1.00
352_L	398_T	1.170	1.00
112_G	153_A	1.170	1.00
338_S	341_I	1.163	1.00
52_T	317_Q	1.157	1.00
193_G	199_F	1.157	1.00
194_L	197_P	1.155	1.00
380_L	385_P	1.150	1.00
335_G	338_S	1.147	1.00
230_L	234_I	1.140	1.00
394_A	440_V	1.135	0.99
187_P	191_C	1.134	0.99
21_L	24_K	1.133	0.99
183_L	188_S	1.127	0.99
51_H	54_K	1.108	0.99
384_N	387_L	1.108	0.99
177_V	183_L	1.106	0.99
16_M	34_A	1.100	0.99
186_I	189_V	1.098	0.99
257_E	260_N	1.095	0.99
17_L	21_L	1.095	0.99
30_A	34_A	1.094	0.99
107_I	111_F	1.092	0.99
174_M	182_V	1.091	0.99
108_G	112_G	1.091	0.99
257_E	261_F	1.086	0.99
231_V	236_A	1.082	0.99
121_F	413_Y	1.080	0.99
177_V	182_V	1.075	0.99
265_S	268_A	1.074	0.99
227_V	230_L	1.071	0.99
83_A	228_S	1.071	0.99
264_S	267_I	1.069	0.99
194_L	199_F	1.050	0.99
174_M	177_V	1.046	0.99
15_L	22_K	1.046	0.99
34_A	38_V	1.044	0.99
419_K	423_K	1.042	0.99
421_T	425_W	1.040	0.99
302_I	306_I	1.040	0.99
176_M	181_G	1.037	0.99
57_F	65_A	1.030	0.99
81_S	280_F	1.026	0.99
176_M	184_V	1.025	0.99
176_M	183_L	1.024	0.99
105_I	189_V	1.022	0.99
213_A	216_P	1.016	0.99
74_I	273_M	1.008	0.99
226_G	231_V	1.003	0.99
369_S	373_L	1.001	0.99
411_K	418_V	1.000	0.99
405_A	408_W	0.996	0.99
246_N	249_L	0.994	0.99
245_A	249_L	0.992	0.99
272_A	276_A	0.991	0.99
188_S	192_A	0.991	0.99
34_A	37_S	0.989	0.99
258_V	263_G	0.987	0.99
137_I	141_K	0.979	0.98
175_G	182_V	0.972	0.98
259_V	262_I	0.969	0.98
117_Y	120_A	0.968	0.98
384_N	388_L	0.966	0.98
55_A	58_G	0.965	0.98
420_D	423_K	0.963	0.98
172_A	178_Y	0.962	0.98
17_L	25_I	0.961	0.98
400_T	425_W	0.958	0.98
200_L	204_E	0.957	0.98
398_T	430_L	0.955	0.98
183_L	190_I	0.949	0.98
235_P	247_I	0.947	0.98
197_P	202_N	0.941	0.98
223_P	227_V	0.941	0.98
184_V	439_I	0.940	0.98
13_I	17_L	0.938	0.98
89_H	222_L	0.933	0.98
61_L	310_G	0.931	0.98
437_L	441_L	0.931	0.98
173_D	180_Y	0.930	0.98
246_N	250_V	0.929	0.98
235_P	240_I	0.926	0.98
173_D	179_I	0.925	0.98
80_D	290_W	0.924	0.98
38_V	315_L	0.918	0.98
234_I	238_I	0.917	0.98
172_A	181_G	0.917	0.98
193_G	200_L	0.916	0.98
317_Q	320_I	0.915	0.98
182_V	185_T	0.913	0.98
360_S	404_D	0.911	0.98
15_L	20_N	0.911	0.98
89_H	134_E	0.909	0.98
27_S	38_V	0.907	0.97
246_N	260_N	0.906	0.97
13_I	20_N	0.906	0.97
17_L	22_K	0.901	0.97
202_N	206_P	0.899	0.97
53_M	314_V	0.899	0.97
9_V	13_I	0.894	0.97
193_G	198_K	0.891	0.97
180_Y	386_A	0.889	0.97
163_P	167_V	0.887	0.97
325_G	329_G	0.887	0.97
240_I	244_I	0.885	0.97
174_M	179_I	0.885	0.97
153_A	160_Q	0.883	0.97
293_N	297_S	0.883	0.97
10_V	14_G	0.879	0.97
6_I	10_V	0.874	0.97
239_M	243_T	0.872	0.97
12_G	37_S	0.871	0.97
47_M	51_H	0.870	0.97
44_M	49_L	0.869	0.97
290_W	293_N	0.869	0.97
399_L	422_L	0.864	0.97
178_Y	186_I	0.863	0.97
410_F	413_Y	0.862	0.97
18_V	21_L	0.862	0.97
101_Q	104_V	0.858	0.96
196_L	201_G	0.857	0.96
234_I	239_M	0.857	0.96
243_T	247_I	0.855	0.96
230_L	237_I	0.855	0.96
226_G	232_P	0.851	0.96
28_M	307_L	0.849	0.96
203_L	208_P	0.847	0.96
436_G	440_V	0.846	0.96
175_G	181_G	0.846	0.96
20_N	25_I	0.844	0.96
243_T	246_N	0.840	0.96
348_V	352_L	0.837	0.96
86_Q	225_F	0.837	0.96
429_E	432_N	0.835	0.96
266_P	269_M	0.834	0.96
405_A	411_K	0.833	0.96
211_L	214_D	0.833	0.96
202_N	205_R	0.832	0.96
229_I	232_P	0.832	0.96
183_L	189_V	0.830	0.96
224_S	231_V	0.829	0.96
344_W	437_L	0.827	0.96
231_V	234_I	0.825	0.96
194_L	201_G	0.824	0.96
89_H	93_A	0.823	0.96
181_G	189_V	0.823	0.96
225_F	232_P	0.821	0.96
151_T	429_E	0.820	0.95
104_V	108_G	0.819	0.95
351_R	404_D	0.819	0.95
15_L	18_V	0.816	0.95
14_G	24_K	0.814	0.95
148_A	428_L	0.813	0.95
44_M	52_T	0.812	0.95
182_V	187_P	0.810	0.95
19_L	22_K	0.808	0.95
175_G	184_V	0.807	0.95
200_L	206_P	0.807	0.95
164_V	167_V	0.805	0.95
16_M	20_N	0.804	0.95
60_T	313_G	0.803	0.95
40_M	46_L	0.802	0.95
72_A	295_F	0.800	0.95
323_G	326_D	0.799	0.95
359_V	363_T	0.799	0.95
112_G	120_A	0.796	0.95
390_L	440_V	0.795	0.95
381_V	384_N	0.793	0.95
424_T	427_L	0.793	0.95
386_A	390_L	0.792	0.95
361_A	396_S	0.791	0.95
44_M	47_M	0.789	0.94
42_A	322_T	0.787	0.94
187_P	190_I	0.779	0.94
336_N	341_I	0.777	0.94
235_P	243_T	0.776	0.94
422_L	426_G	0.775	0.94
39_G	49_L	0.774	0.94
220_N	228_S	0.773	0.94
225_F	231_V	0.773	0.94
328_I	332_M	0.773	0.94
117_Y	121_F	0.773	0.94
226_G	239_M	0.772	0.94
115_M	269_M	0.771	0.94
335_G	339_P	0.769	0.94
36_L	267_I	0.766	0.94
13_I	16_M	0.766	0.94
357_G	396_S	0.763	0.93
231_V	247_I	0.762	0.93
16_M	24_K	0.762	0.93
66_I	70_F	0.761	0.93
230_L	235_P	0.760	0.93
17_L	20_N	0.759	0.93
194_L	198_K	0.759	0.93
337_I	340_Y	0.757	0.93
269_M	273_M	0.755	0.93
387_L	444_S	0.752	0.93
250_V	256_W	0.751	0.93
189_V	193_G	0.750	0.93
148_A	193_G	0.748	0.93
439_I	442_I	0.746	0.93
268_A	273_M	0.744	0.93
191_C	195_I	0.740	0.92
225_F	239_M	0.739	0.92
340_Y	383_V	0.738	0.92
217_V	221_N	0.736	0.92
222_L	228_S	0.733	0.92
356_Q	359_V	0.731	0.92
63_E	66_I	0.731	0.92
11_F	15_L	0.731	0.92
16_M	21_L	0.731	0.92
52_T	56_G	0.731	0.92
257_E	262_I	0.729	0.92
22_K	25_I	0.727	0.92
165_A	362_M	0.726	0.92
84_A	88_A	0.724	0.91
235_P	238_I	0.724	0.91
212_K	215_Q	0.723	0.91
175_G	183_L	0.722	0.91
108_G	124_L	0.720	0.91
201_G	207_T	0.717	0.91
49_L	318_T	0.715	0.91
245_A	259_V	0.714	0.91
428_L	432_N	0.713	0.91
244_I	248_W	0.712	0.91
128_V	146_A	0.708	0.91
262_I	266_P	0.708	0.91
101_Q	105_I	0.707	0.90
332_M	346_I	0.706	0.90
231_V	279_L	0.706	0.90
151_T	397_N	0.703	0.90
259_V	263_G	0.701	0.90
102_L	193_G	0.700	0.90
400_T	429_E	0.699	0.90
30_A	36_L	0.699	0.90
172_A	175_G	0.698	0.90
273_M	276_A	0.698	0.90
14_G	21_L	0.693	0.90
172_A	187_P	0.691	0.89
177_V	184_V	0.691	0.89
357_G	400_T	0.687	0.89
74_I	272_A	0.686	0.89
136_K	207_T	0.684	0.89
19_L	25_I	0.680	0.89
201_G	204_E	0.679	0.89
228_S	247_I	0.678	0.89
409_L	412_G	0.676	0.88
56_G	59_N	0.676	0.88
16_M	19_L	0.675	0.88
373_L	385_P	0.674	0.88
217_V	220_N	0.674	0.88
114_A	118_E	0.673	0.88
277_F	295_F	0.673	0.88
188_S	439_I	0.673	0.88
181_G	186_I	0.670	0.88
192_A	196_L	0.667	0.88
153_A	157_F	0.665	0.88
174_M	180_Y	0.663	0.87
173_D	181_G	0.661	0.87
155_S	166_L	0.659	0.87
407_F	410_F	0.659	0.87
31_L	34_A	0.656	0.87
21_L	25_I	0.655	0.87
249_L	256_W	0.654	0.87
44_M	322_T	0.654	0.87
269_M	272_A	0.653	0.87
17_L	24_K	0.652	0.87
387_L	440_V	0.652	0.87
8_W	42_A	0.651	0.87
8_W	12_G	0.651	0.87
146_A	414_F	0.650	0.86
231_V	243_T	0.650	0.86
120_A	150_A	0.649	0.86
226_G	229_I	0.647	0.86
212_K	216_P	0.646	0.86
416_L	420_D	0.646	0.86
42_A	49_L	0.644	0.86
144_I	148_A	0.644	0.86
242_T	245_A	0.643	0.86
118_E	122_I	0.640	0.86
121_F	125_A	0.639	0.85
383_V	388_L	0.639	0.85
351_R	400_T	0.639	0.85
260_N	265_S	0.638	0.85
234_I	272_A	0.637	0.85
12_G	42_A	0.637	0.85
195_I	200_L	0.636	0.85
154_H	160_Q	0.635	0.85
410_F	414_F	0.635	0.85
277_F	291_V	0.634	0.85
401_H	429_E	0.632	0.85
102_L	194_L	0.632	0.85
308_I	362_M	0.632	0.85
418_V	422_L	0.631	0.85
156_L	394_A	0.628	0.85
174_M	184_V	0.627	0.84
238_I	242_T	0.627	0.84
76_K	294_A	0.626	0.84
156_L	436_G	0.626	0.84
133_A	139_F	0.625	0.84
78_M	83_A	0.625	0.84
197_P	201_G	0.625	0.84
357_G	405_A	0.624	0.84
26_N	29_V	0.623	0.84
342_M	372_I	0.622	0.84
132_A	137_I	0.621	0.84
264_S	272_A	0.620	0.84
262_I	265_S	0.619	0.84
386_A	389_V	0.619	0.84
424_T	428_L	0.616	0.83
154_H	358_V	0.614	0.83
38_V	41_L	0.612	0.83
228_S	234_I	0.612	0.83
120_A	124_L	0.611	0.83
86_Q	222_L	0.611	0.83
183_L	192_A	0.611	0.83
405_A	409_L	0.610	0.83
31_L	38_V	0.609	0.83
233_L	237_I	0.609	0.83
169_A	366_G	0.608	0.83
86_Q	224_S	0.607	0.82
201_G	206_P	0.606	0.82
354_T	360_S	0.606	0.82
188_S	435_V	0.605	0.82
83_A	280_F	0.604	0.82
439_I	443_I	0.603	0.82
361_A	364_A	0.603	0.82
230_L	279_L	0.603	0.82
227_V	236_A	0.601	0.82
214_D	217_V	0.600	0.82
341_I	441_L	0.598	0.82
184_V	390_L	0.598	0.82
97_L	135_A	0.598	0.82
180_Y	390_L	0.597	0.81
13_I	24_K	0.597	0.81
141_K	145_P	0.597	0.81
182_V	188_S	0.593	0.81
407_F	413_Y	0.592	0.81
177_V	187_P	0.590	0.81
149_A	153_A	0.586	0.80
15_L	21_L	0.584	0.80
76_K	297_S	0.583	0.80
232_P	243_T	0.581	0.80
177_V	386_A	0.578	0.79
343_A	347_T	0.577	0.79
399_L	430_L	0.575	0.79
112_G	160_Q	0.575	0.79
177_V	186_I	0.574	0.79
152_T	432_N	0.573	0.79
63_E	67_I	0.572	0.79
217_V	224_S	0.572	0.79
116_F	119_V	0.572	0.79
231_V	240_I	0.571	0.79
157_F	160_Q	0.570	0.78
186_I	191_C	0.569	0.78
351_R	357_G	0.567	0.78
146_A	149_A	0.566	0.78
37_S	40_M	0.566	0.78
401_H	424_T	0.565	0.78
109_L	113_L	0.565	0.78
50_L	54_K	0.564	0.78
7_L	11_F	0.564	0.78
337_I	341_I	0.563	0.78
227_V	279_L	0.561	0.77
113_L	153_A	0.561	0.77
350_I	354_T	0.560	0.77
261_F	264_S	0.560	0.77
267_I	271_I	0.559	0.77
212_K	221_N	0.558	0.77
55_A	317_Q	0.558	0.77
273_M	279_L	0.557	0.77
195_I	201_G	0.557	0.77
54_K	63_E	0.557	0.77
167_V	171_G	0.556	0.77
38_V	324_I	0.556	0.77
219_M	223_P	0.556	0.77
109_L	152_T	0.556	0.77
440_V	444_S	0.556	0.77
259_V	265_S	0.556	0.77
86_Q	228_S	0.555	0.77
218_D	221_N	0.555	0.77
407_F	411_K	0.554	0.76
102_L	105_I	0.552	0.76
165_A	170_Y	0.552	0.76
236_A	239_M	0.552	0.76
400_T	403_N	0.551	0.76
287_D	291_V	0.550	0.76
228_S	244_I	0.550	0.76
276_A	279_L	0.548	0.76
245_A	250_V	0.547	0.76
185_T	190_I	0.547	0.76
116_F	120_A	0.547	0.76
227_V	232_P	0.546	0.75
179_I	186_I	0.546	0.75
260_N	263_G	0.546	0.75
179_I	187_P	0.545	0.75
199_F	207_T	0.545	0.75
286_H	291_V	0.543	0.75
8_W	34_A	0.542	0.75
435_V	439_I	0.542	0.75
35_A	314_V	0.541	0.75
120_A	160_Q	0.541	0.75
409_L	416_L	0.541	0.75
226_G	248_W	0.539	0.74
425_W	428_L	0.539	0.74
406_S	411_K	0.539	0.74
402_I	422_L	0.538	0.74
335_G	341_I	0.538	0.74
242_T	248_W	0.538	0.74
178_Y	189_V	0.538	0.74
239_M	247_I	0.538	0.74
87_I	117_Y	0.538	0.74
91_L	95_L	0.537	0.74
224_S	232_P	0.537	0.74
262_I	269_M	0.536	0.74
32_L	70_F	0.534	0.74
52_T	55_A	0.534	0.74
152_T	185_T	0.534	0.74
209_S	212_K	0.533	0.74
8_W	37_S	0.533	0.74
426_G	430_L	0.533	0.74
265_S	276_A	0.531	0.73
198_K	206_P	0.531	0.73
27_S	31_L	0.530	0.73
373_L	388_L	0.529	0.73
245_A	248_W	0.528	0.73
223_P	239_M	0.528	0.73
172_A	179_I	0.527	0.73
160_Q	309_I	0.527	0.73
42_A	47_M	0.524	0.72
357_G	429_E	0.524	0.72
214_D	218_D	0.524	0.72
219_M	222_L	0.523	0.72
226_G	247_I	0.523	0.72
196_L	431_V	0.522	0.72
199_F	205_R	0.522	0.72
280_F	291_V	0.522	0.72
238_I	275_V	0.522	0.72
210_F	215_Q	0.522	0.72
112_G	116_F	0.521	0.72
94_R	278_V	0.520	0.72
331_L	334_H	0.520	0.72
193_G	203_L	0.520	0.72
8_W	38_V	0.520	0.72
119_V	162_G	0.519	0.72
304_M	308_I	0.518	0.72
419_K	422_L	0.518	0.72
425_W	429_E	0.517	0.71
421_T	428_L	0.517	0.71
211_L	217_V	0.517	0.71
209_S	215_Q	0.517	0.71
409_L	413_Y	0.516	0.71
147_V	428_L	0.515	0.71
404_D	425_W	0.512	0.71
19_L	33_V	0.511	0.71
343_A	368_I	0.511	0.71
100_V	104_V	0.511	0.71
42_A	45_D	0.511	0.71
180_Y	187_P	0.510	0.70
141_K	201_G	0.510	0.70
181_G	190_I	0.509	0.70
192_A	198_K	0.506	0.70
173_D	183_L	0.506	0.70
256_W	262_I	0.502	0.69
229_I	239_M	0.502	0.69
406_S	409_L	0.502	0.69
224_S	239_M	0.501	0.69
93_A	290_W	0.500	0.69

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4r1iA	2	0.9664	100	0.665	Contact Map
4r0cA	3	0.9642	100	0.67	Contact Map
4f35D	2	0.8904	100	0.699	Contact Map
3qe7A	2	0.4452	82.8	0.95	Contact Map
4dx5A	3	0.3602	77.5	0.953	Contact Map
3aqpA	1	0.3333	65.5	0.957	Contact Map
3w9iA	3	0.3378	60.6	0.958	Contact Map
2cfqA	1	0.8166	59.4	0.958	Contact Map
3giaA	1	0.4474	58.3	0.959	Contact Map
3qnqA	2	0.4609	44.4	0.962	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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