GREMLIN Database
NRDH - Glutaredoxin-like protein NrdH
UniProt: P0AC65 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13286
Length: 81 (72)
Sequences: 571 (265)
Seq/√Len: 31.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
22_E28_F5.1251.00
48_F60_S3.4281.00
3_I26_F3.2861.00
20_A69_I2.4740.99
18_K30_M2.1850.99
43_L46_Q2.1770.99
42_A55_I2.0060.97
68_M71_R1.9920.97
40_A44_R1.9700.97
7_T30_M1.9690.97
9_N32_N1.9580.97
9_N34_D1.9000.96
41_E45_A1.5730.90
7_T18_K1.5610.90
44_R49_R1.5600.90
40_A51_L1.4950.88
33_V40_A1.4480.86
40_A49_R1.4250.85
8_R13_Q1.3650.83
16_A50_Q1.3510.82
61_W69_I1.3030.80
10_D18_K1.2660.78
59_L68_M1.2410.76
5_I21_M1.2240.75
24_R70_N1.2140.75
50_Q62_S1.1970.74
42_A45_A1.1780.72
5_I25_G1.1310.69
41_E44_R1.1030.67
46_Q60_S1.0850.66
13_Q16_A1.0590.64
12_V20_A1.0330.62
4_T35_R1.0200.61
24_R44_R1.0090.60
5_I54_V0.9990.59
43_L55_I0.9880.59
18_K28_F0.9600.56
10_D15_H0.9250.53
25_G59_L0.8880.51
51_L62_S0.8880.51
20_A61_W0.8560.48
2_R34_D0.8540.48
27_D45_A0.8390.47
17_T61_W0.8320.46
12_V50_Q0.8230.45
5_I67_D0.7960.43
19_R29_E0.7890.43
58_D68_M0.7880.42
27_D72_L0.7850.42
32_N43_L0.7830.42
16_A23_N0.7620.40
42_A68_M0.7600.40
3_I72_L0.7520.40
13_Q63_G0.7510.40
8_R48_F0.7430.39
20_A24_R0.7400.39
33_V38_E0.7370.38
23_N70_N0.7300.38
7_T12_V0.7200.37
57_G62_S0.7170.37
7_T40_A0.7110.37
55_I60_S0.6920.35
33_V42_A0.6910.35
42_A56_A0.6890.35
27_D36_V0.6800.34
19_R45_A0.6740.34
12_V15_H0.6730.34
6_Y42_A0.6710.34
26_F70_N0.6640.33
2_R41_E0.6620.33
43_L72_L0.6530.32
12_V67_D0.6440.32
3_I34_D0.6420.32
24_R58_D0.6410.31
68_M73_H0.6400.31
2_R55_I0.6220.30
21_M69_I0.6190.30
12_V66_P0.6130.30
16_A61_W0.6120.29
31_I61_W0.6120.29
33_V43_L0.6070.29
12_V64_F0.6070.29
5_I51_L0.5990.29
10_D64_F0.5830.28
26_F72_L0.5810.27
19_R23_N0.5780.27
54_V65_R0.5770.27
42_A46_Q0.5730.27
7_T25_G0.5670.27
22_E25_G0.5660.26
10_D70_N0.5550.26
36_V60_S0.5530.26
56_A68_M0.5510.26
15_H23_N0.5500.25
7_T57_G0.5500.25
8_R63_G0.5450.25
21_M54_V0.5450.25
34_D37_P0.5400.25
9_N36_V0.5280.24
12_V69_I0.5260.24
8_R51_L0.5250.24
55_I61_W0.5220.24
17_T54_V0.5160.23
39_A57_G0.5140.23
16_A20_A0.5120.23
59_L73_H0.5100.23
19_R64_F0.5040.23
5_I18_K0.5000.23
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2ct6A 1 1 99.5 0.605 Contact Map
3gkxA 2 0.9012 99.5 0.608 Contact Map
1u6tA 1 0.9877 99.5 0.611 Contact Map
4k8mA 2 0.9877 99.5 0.614 Contact Map
2m46A 1 0.9012 99.4 0.616 Contact Map
1z3eA 1 0.9506 99.4 0.619 Contact Map
2kokA 1 0.9259 99.4 0.626 Contact Map
2jadA 1 0.963 99.4 0.627 Contact Map
3rdwA 1 0.8765 99.4 0.631 Contact Map
1rw1A 1 0.9012 99.4 0.632 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0048 seconds.