GREMLIN Database
FLIQ - Flagellar biosynthetic protein FliQ
UniProt: P0AC07 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11976
Length: 89 (86)
Sequences: 1786 (1139)
Seq/√Len: 122.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
31_T57_A4.1551.00
27_V57_A3.2451.00
27_V61_A3.2121.00
12_E79_T2.6371.00
61_A65_A2.6041.00
37_I41_A2.5341.00
20_L69_M2.1571.00
17_A59_F2.1131.00
26_L30_V2.0941.00
74_L78_R1.9461.00
78_R82_T1.6841.00
41_A45_N1.6421.00
19_A72_L1.6351.00
56_I60_I1.5701.00
28_A58_V1.5091.00
83_N86_Y1.5081.00
79_T83_N1.4831.00
16_V72_L1.4651.00
40_A45_N1.3721.00
40_A43_Q1.3641.00
12_E15_K1.3571.00
46_E49_L1.3081.00
77_V81_F1.3011.00
45_N75_D1.2941.00
24_L69_M1.2390.99
34_I38_L1.2330.99
14_M59_F1.2260.99
81_F84_L1.2250.99
8_M11_T1.1890.99
47_M50_S1.1770.99
18_L56_I1.1720.99
50_S53_P1.1720.99
79_T82_T1.1540.99
27_V65_A1.1390.99
36_S58_V1.1220.99
11_T15_K1.0870.99
29_L53_P1.0860.99
45_N49_L1.0780.99
22_A26_L1.0770.98
47_M52_I1.0760.98
60_I64_I1.0610.98
24_L62_I1.0480.98
23_P54_K1.0460.98
15_K19_A1.0400.98
24_L46_E1.0390.98
23_P27_V1.0240.98
35_I52_I0.9960.97
20_L73_L0.9930.97
17_A21_A0.9870.97
27_V31_T0.9830.97
16_V20_L0.9620.97
71_N75_D0.9610.97
28_A50_S0.9440.97
24_L65_A0.9350.96
55_I67_P0.9200.96
8_M12_E0.8990.95
25_L36_S0.8950.95
70_L74_L0.8910.95
38_L44_I0.8850.95
16_V19_A0.8740.95
28_A48_T0.8650.94
25_L52_I0.8600.94
59_F63_I0.8510.94
5_S83_N0.7920.91
21_A52_I0.7910.91
68_W72_L0.7830.91
12_E76_Y0.7750.90
77_V80_L0.7670.90
3_P67_P0.7520.89
10_G18_L0.7510.89
75_D78_R0.7490.89
75_D79_T0.7470.89
2_T5_S0.7370.88
36_S43_Q0.7340.88
46_E50_S0.7320.88
10_G14_M0.7260.87
15_K45_N0.7250.87
23_P45_N0.7160.87
4_E8_M0.7110.86
5_S8_M0.7070.86
44_I48_T0.6930.85
33_L50_S0.6880.84
13_A40_A0.6720.83
17_A66_G0.6700.83
29_L51_F0.6660.82
26_L62_I0.6640.82
66_G70_L0.6580.82
2_T63_I0.6570.81
24_L61_A0.6540.81
8_M82_T0.6480.81
43_Q67_P0.6480.81
53_P59_F0.6450.80
36_S68_W0.6420.80
81_F85_P0.6410.80
14_M63_I0.6410.80
60_I78_R0.6340.79
13_A46_E0.6320.79
10_G59_F0.6300.79
8_M14_M0.6170.77
23_P76_Y0.6160.77
36_S50_S0.6020.76
33_L44_I0.5910.74
33_L79_T0.5890.74
55_I59_F0.5840.73
20_L43_Q0.5800.73
24_L58_V0.5590.70
80_L85_P0.5550.70
3_P6_V0.5540.69
41_A81_F0.5530.69
54_K84_L0.5530.69
15_K25_L0.5490.69
33_L53_P0.5470.68
38_L59_F0.5450.68
7_M11_T0.5430.68
3_P74_L0.5360.67
43_Q77_V0.5340.67
46_E66_G0.5330.66
28_A38_L0.5300.66
55_I58_V0.5270.66
33_L37_I0.5250.65
62_I65_A0.5220.65
76_Y86_Y0.5160.64
8_M83_N0.5150.64
7_M43_Q0.5110.63
65_A69_M0.5110.63
12_E83_N0.5090.63
41_A66_G0.5070.63
35_I53_P0.5060.63
25_L67_P0.5000.62
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4pd6A 3 0.3933 22.9 0.905 Contact Map
3tuiA 2 0.9775 5 0.93 Contact Map
4ymuD 2 0.9888 4 0.933 Contact Map
3rlfF 1 0.9888 3.2 0.936 Contact Map
3mktA 1 0.9888 2.3 0.941 Contact Map
2fyuK 1 0.5393 2.1 0.942 Contact Map
4humA 1 0.9888 2 0.942 Contact Map
4dxwA 3 0.4831 2 0.943 Contact Map
4ij3C 1 0 1.4 0.948 Contact Map
3d31C 2 0.9888 1.4 0.948 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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