GREMLIN Database
FLIP - Flagellar biosynthetic protein FliP
UniProt: P0AC05 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11975
Length: 245 (213)
Sequences: 1946 (1027)
Seq/√Len: 70.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
108_I134_L5.5941.00
107_K111_D4.8931.00
109_Y114_Q3.8121.00
122_S125_E3.3631.00
131_A167_M3.1621.00
68_I89_L2.7341.00
108_I112_A2.7111.00
121_I129_K2.6741.00
67_I100_I2.6421.00
85_P88_V2.5231.00
165_V170_L2.5211.00
67_I71_F2.5031.00
63_S100_I2.4451.00
148_G152_R2.3971.00
114_Q118_E2.3671.00
150_F176_T2.3661.00
143_R146_D2.3411.00
77_A190_F2.3011.00
102_S105_I2.2311.00
69_I179_L2.2291.00
70_V239_L2.2221.00
153_L240_A2.2221.00
135_R167_M2.1281.00
139_L162_P2.1191.00
89_L93_A2.0811.00
167_M171_L2.0051.00
50_S57_I1.9291.00
75_R86_N1.9101.00
139_L170_L1.8571.00
139_L167_M1.8311.00
113_Y117_S1.8271.00
111_D129_K1.7811.00
109_Y113_Y1.7701.00
145_A233_Q1.7261.00
237_G241_Q1.7221.00
129_K132_Q1.6861.00
125_E129_K1.6861.00
135_R170_L1.6641.00
156_T166_P1.6600.99
91_G175_V1.6460.99
107_K136_E1.6310.99
53_F57_I1.6240.99
207_L216_T1.6020.99
104_V107_K1.5930.99
46_V50_S1.5860.99
60_M175_V1.5780.99
137_F174_Y1.5120.99
112_A130_G1.4960.99
75_R84_P1.4740.99
61_M134_L1.4140.98
125_E128_E1.3880.98
131_A135_R1.3590.98
135_R139_L1.3410.98
114_Q117_S1.3400.98
177_S181_T1.3130.97
195_I199_V1.3110.97
151_A154_A1.3020.97
151_A159_L1.3000.97
66_R243_F1.2670.97
176_T233_Q1.2540.96
42_V46_V1.2390.96
68_I93_A1.2260.96
73_L223_L1.2100.96
61_M65_T1.2020.96
73_L80_T1.2010.96
136_E140_R1.2000.95
149_L152_R1.1910.95
230_D233_Q1.1880.95
106_D110_V1.1860.95
185_I239_L1.1810.95
34_G38_W1.1800.95
190_F194_L1.1710.95
191_I195_I1.1590.95
156_T169_I1.1570.94
127_L130_G1.1550.94
132_Q135_R1.1430.94
72_G82_S1.1420.94
141_Q243_F1.1300.94
154_A168_R1.1160.93
128_E131_A1.1070.93
60_M91_G1.1020.93
143_R181_T1.1000.93
71_F235_L1.0910.93
68_I72_G1.0880.92
180_K184_Q1.0880.92
60_M92_L1.0860.92
199_V223_L1.0790.92
74_L237_G1.0750.92
110_V114_Q1.0720.92
130_G133_P1.0710.92
40_L43_Q1.0710.92
171_L175_V1.0670.92
142_T147_L1.0560.91
32_P37_S1.0560.91
44_T189_I1.0550.91
161_G164_A1.0400.91
160_Q164_A1.0380.91
70_V182_A1.0370.91
77_A223_L1.0310.90
149_L176_T1.0290.90
65_T88_V1.0160.90
176_T236_V1.0040.89
67_I96_L1.0010.89
123_M127_L1.0010.89
80_T84_P0.9990.89
71_F74_L0.9950.89
63_S67_I0.9880.88
51_L173_A0.9830.88
106_D168_R0.9800.88
102_S106_D0.9740.88
152_R158_P0.9680.87
60_M207_L0.9600.87
181_T184_Q0.9560.87
31_L37_S0.9450.86
71_F89_L0.9420.86
80_T191_I0.9400.86
67_I243_F0.9390.86
74_L235_L0.9390.86
211_M219_L0.9280.85
104_V184_Q0.9140.84
68_I90_L0.9130.84
144_E148_G0.9060.83
233_Q236_V0.9050.83
73_L216_T0.9030.83
38_W41_P0.9030.83
127_L167_M0.9010.83
50_S53_F0.8970.83
229_V238_S0.8950.83
116_F121_I0.8920.83
70_V185_I0.8870.82
149_L233_Q0.8840.82
41_P44_T0.8770.81
82_S204_L0.8690.81
76_N83_A0.8590.80
87_Q90_L0.8530.80
127_L131_A0.8500.79
74_L79_G0.8490.79
159_L165_V0.8480.79
169_I173_A0.8470.79
95_F172_P0.8400.79
31_L34_G0.8380.78
101_M137_F0.8210.77
139_L165_V0.8190.77
116_F126_A0.8140.76
38_W46_V0.8140.76
109_Y112_A0.8120.76
31_L35_G0.8120.76
82_S215_A0.8110.76
184_Q188_T0.8090.76
138_M141_Q0.8020.75
182_A204_L0.7960.75
85_P204_L0.7960.75
33_G140_R0.7930.74
53_F56_A0.7920.74
76_N216_T0.7920.74
189_I229_V0.7830.74
236_V242_S0.7820.73
135_R165_V0.7820.73
69_I185_I0.7810.73
211_M218_A0.7800.73
71_F100_I0.7740.73
224_M236_V0.7630.72
96_L182_A0.7630.72
159_L166_P0.7610.71
54_I176_T0.7600.71
109_Y118_E0.7570.71
110_V120_K0.7550.71
148_G158_P0.7540.71
59_L87_Q0.7540.71
94_L99_F0.7490.70
94_L98_F0.7480.70
42_V116_F0.7450.70
154_A169_I0.7440.70
223_L235_L0.7430.70
111_D132_Q0.7420.69
96_L153_L0.7410.69
120_K160_Q0.7400.69
74_L189_I0.7320.68
176_T240_A0.7310.68
69_I189_I0.7300.68
143_R150_F0.7290.68
180_K230_D0.7250.68
69_I98_F0.7200.67
191_I225_L0.7200.67
48_I61_M0.7180.67
85_P96_L0.7170.67
150_F169_I0.7150.67
110_V118_E0.7140.67
81_P189_I0.7140.67
74_L184_Q0.7130.66
98_F102_S0.7100.66
58_L105_I0.7070.66
121_I126_A0.7040.65
237_G242_S0.7040.65
32_P35_G0.7040.65
135_R168_R0.6940.64
40_L44_T0.6930.64
189_I235_L0.6900.64
129_K140_R0.6870.64
120_K129_K0.6870.64
75_R210_M0.6820.63
184_Q230_D0.6810.63
95_F171_L0.6760.62
80_T198_L0.6710.62
68_I85_P0.6710.62
92_L176_T0.6690.61
132_Q136_E0.6670.61
130_G134_L0.6670.61
195_I212_V0.6650.61
50_S54_I0.6640.61
137_F141_Q0.6550.60
159_L213_P0.6550.60
35_G38_W0.6550.60
146_D180_K0.6540.60
46_V88_V0.6530.60
144_E161_G0.6490.59
121_I125_E0.6470.59
146_D237_G0.6440.59
78_L239_L0.6430.58
36_Q39_S0.6370.58
110_V155_N0.6360.58
48_I213_P0.6300.57
46_V123_M0.6300.57
52_T166_P0.6290.57
43_Q237_G0.6250.56
35_G39_S0.6240.56
70_V190_F0.6220.56
54_I213_P0.6210.56
72_G76_N0.6180.55
56_A60_M0.6180.55
132_Q201_A0.6170.55
40_L58_L0.6170.55
190_F223_L0.6160.55
70_V84_P0.6150.55
140_R156_T0.6080.54
73_L81_P0.6070.54
67_I239_L0.6060.54
97_T105_I0.6030.54
132_Q167_M0.6000.53
178_E181_T0.5990.53
87_Q225_L0.5990.53
171_L174_Y0.5960.53
49_T52_T0.5950.53
31_L203_V0.5930.52
91_G221_F0.5910.52
107_K110_V0.5910.52
34_G37_S0.5910.52
49_T115_P0.5880.52
116_F123_M0.5850.51
73_L213_P0.5850.51
57_I98_F0.5850.51
61_M175_V0.5850.51
38_W181_T0.5840.51
199_V221_F0.5830.51
55_P101_M0.5830.51
129_K163_E0.5820.51
80_T216_T0.5810.51
192_P201_A0.5770.51
91_G225_L0.5760.50
73_L207_L0.5750.50
159_L169_I0.5710.50
58_L146_D0.5710.50
209_M218_A0.5660.49
38_W213_P0.5640.49
58_L71_F0.5630.49
237_G240_A0.5620.49
79_G82_S0.5600.48
44_T53_F0.5590.48
112_A121_I0.5590.48
135_R163_E0.5560.48
151_A157_G0.5550.48
74_L191_I0.5500.47
110_V124_Q0.5480.47
36_Q200_I0.5460.47
145_A241_Q0.5430.46
68_I83_A0.5430.46
97_T223_L0.5430.46
80_T223_L0.5420.46
32_P45_L0.5420.46
145_A150_F0.5410.46
48_I52_T0.5380.46
48_I140_R0.5360.46
159_L164_A0.5350.45
66_R181_T0.5320.45
52_T59_L0.5310.45
58_L94_L0.5300.45
121_I130_G0.5290.45
85_P104_V0.5280.45
64_F90_L0.5270.44
142_T181_T0.5270.44
148_G161_G0.5260.44
60_M65_T0.5260.44
71_F92_L0.5240.44
109_Y194_L0.5240.44
189_I223_L0.5230.44
140_R160_Q0.5230.44
83_A229_V0.5230.44
212_V217_I0.5220.44
194_L217_I0.5210.44
234_L243_F0.5200.44
120_K136_E0.5190.43
107_K124_Q0.5190.43
224_M227_V0.5180.43
39_S223_L0.5160.43
118_E125_E0.5150.43
43_Q66_R0.5140.43
190_F219_L0.5130.43
147_L170_L0.5120.43
96_L196_I0.5110.43
143_R184_Q0.5100.42
210_M237_G0.5100.42
152_R181_T0.5070.42
147_L165_V0.5060.42
54_I91_G0.5060.42
87_Q236_V0.5040.42
43_Q203_V0.5020.41
38_W159_L0.5010.41
56_A76_N0.5000.41
180_K212_V0.5000.41
98_F168_R0.5000.41
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1rh5B 1 0.2286 10.7 0.97 Contact Map
4w252 1 0.2531 10.5 0.97 Contact Map
4c7rA 3 0.5551 8.6 0.972 Contact Map
2f6mA 1 0.2531 8.2 0.972 Contact Map
2ww9B 1 0.2449 7.4 0.972 Contact Map
3mp7B 1 0.2204 5.5 0.974 Contact Map
1w53A 2 0.3429 3.5 0.976 Contact Map
1m45B 1 0.102 3 0.977 Contact Map
3jstA 1 0.1265 2.4 0.978 Contact Map
1co4A 1 0.0816 2.2 0.979 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0084 seconds.