GREMLIN Database
FLIG - Flagellar motor switch protein FliG
UniProt: P0ABZ1 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11654
Length: 331 (323)
Sequences: 1454 (870)
Seq/√Len: 48.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
9_K58_E5.7951.00
239_L312_V4.4181.00
243_D246_S4.2311.00
244_D273_K4.1661.00
249_R320_E4.1001.00
268_Q272_E3.9581.00
8_D40_A3.8601.00
258_S307_A3.7421.00
242_V246_S3.7191.00
250_L312_V3.6201.00
275_L287_R3.5341.00
314_R318_T3.4441.00
5_T8_D3.0871.00
244_D276_R2.9391.00
283_A287_R2.8581.00
48_S51_Q2.8291.00
24_E27_K2.7991.00
219_R230_I2.7031.00
13_L17_I2.6831.00
113_M118_A2.6461.00
268_Q271_R2.6341.00
118_A145_I2.6281.00
126_H160_R2.5761.00
197_R232_E2.4661.00
261_I296_V2.4051.00
20_D83_K2.3411.00
248_Q277_N2.3161.00
207_K210_Q2.2961.00
30_S33_E2.2951.00
264_K294_G2.2831.00
130_I153_L2.2751.00
18_G76_Y2.2151.00
199_A229_I2.1701.00
34_V85_L2.1341.00
249_R253_E2.1331.00
247_I277_N2.1321.00
254_V308_I2.0521.00
57_A61_Q1.9530.99
260_L286_L1.9390.99
153_L157_V1.9370.99
236_F262_A1.8690.99
244_D277_N1.8350.99
238_N241_D1.8330.99
73_A77_L1.7910.99
218_V229_I1.7830.99
253_E314_R1.7790.99
260_L293_R1.7560.99
264_K293_R1.7470.99
312_V323_I1.7450.99
122_I130_I1.7320.98
115_P144_D1.7190.98
242_V247_I1.6940.98
272_E287_R1.6880.98
128_Q160_R1.6870.98
303_N307_A1.6780.98
122_I180_N1.6660.98
240_V270_L1.6490.98
204_N236_F1.6320.98
151_E213_A1.6290.98
260_L290_L1.6000.97
156_D160_R1.5970.97
237_E267_E1.5770.97
159_L221_F1.5770.97
23_A84_A1.5570.97
8_D51_Q1.5480.97
76_Y80_V1.5290.97
262_A308_I1.5270.97
216_T220_E1.4990.96
162_A195_G1.4920.96
9_K12_I1.4870.96
129_I238_N1.4800.96
84_A195_G1.4660.96
158_M199_A1.4610.96
58_E62_E1.4230.95
86_G90_A1.4210.95
72_N77_L1.4210.95
197_R201_E1.4180.95
146_L157_V1.4120.95
265_G301_V1.3970.94
251_L254_V1.3720.94
206_M210_Q1.3650.94
246_S250_L1.3420.93
274_F286_L1.3360.93
10_S37_L1.3190.92
158_M229_I1.3130.92
12_I47_I1.3050.92
229_I233_M1.3050.92
200_A232_E1.2980.92
26_F80_V1.2910.92
227_Q231_D1.2870.91
23_A27_K1.2840.91
12_I55_V1.2800.91
254_V311_I1.2770.91
282_A286_L1.2670.91
15_M44_V1.2610.91
161_I202_I1.2590.91
22_A26_F1.2570.90
132_T175_L1.2480.90
29_L37_L1.2440.90
14_L37_L1.2370.90
195_G225_L1.2240.89
86_G225_L1.2220.89
14_L215_I1.2150.89
221_F321_M1.2040.88
128_Q236_F1.1870.88
316_A321_M1.1760.87
15_M65_Q1.1570.86
14_L26_F1.1500.86
149_F157_V1.1430.86
22_A86_G1.1430.86
285_I289_D1.1330.85
130_I157_V1.1180.84
118_A204_N1.0980.83
259_L286_L1.0960.83
284_D287_R1.0940.83
228_K231_D1.0930.83
20_D56_L1.0920.83
203_I206_M1.0850.83
119_A148_L1.0780.82
105_S108_E1.0750.82
236_F308_I1.0740.82
163_T274_F1.0720.82
271_R287_R1.0700.82
183_L315_L1.0620.81
246_S322_V1.0570.81
239_L242_V1.0530.81
15_M47_I1.0510.81
93_L177_E1.0470.80
247_I252_Q1.0440.80
176_T208_T1.0420.80
259_L301_V1.0400.80
108_E192_K1.0360.80
31_Q89_R1.0190.78
136_H280_Q1.0160.78
242_V325_S1.0070.78
272_E276_R1.0020.77
7_T37_L1.0020.77
237_E268_Q1.0010.77
167_V275_L0.9980.77
62_E261_I0.9900.76
290_L293_R0.9900.76
256_S260_L0.9880.76
273_K282_A0.9840.76
227_Q322_V0.9790.76
107_I136_H0.9630.74
251_L311_I0.9560.74
22_A200_A0.9480.73
255_D274_F0.9430.73
171_A328_D0.9380.72
129_I132_T0.9370.72
132_T238_N0.9350.72
120_D123_R0.9350.72
31_Q140_A0.9300.72
203_I214_V0.9210.71
204_N262_A0.9210.71
277_N302_E0.9200.71
92_S95_E0.9180.71
111_N138_K0.9170.71
122_I133_I0.9080.70
242_V250_L0.9070.70
110_L273_K0.9070.70
256_S286_L0.9060.70
170_A303_N0.9060.70
61_Q93_L0.9050.70
152_R177_E0.9000.69
114_E117_S0.8990.69
275_L278_M0.8980.69
122_I290_L0.8950.69
118_A232_E0.8930.69
212_E216_T0.8900.68
82_V87_E0.8870.68
263_L290_L0.8820.68
137_L314_R0.8790.67
252_Q288_D0.8770.67
162_A225_L0.8770.67
102_D201_E0.8730.67
37_L319_G0.8670.66
196_V225_L0.8650.66
52_L167_V0.8640.66
80_V108_E0.8630.66
271_R275_L0.8620.66
34_V305_Q0.8600.66
242_V321_M0.8600.66
50_K54_D0.8540.65
229_I305_Q0.8520.65
215_I230_I0.8450.64
231_D306_K0.8450.64
135_V266_A0.8430.64
119_A145_I0.8430.64
33_E126_H0.8420.64
8_D50_K0.8410.64
7_T36_T0.8390.64
107_I182_L0.8350.63
234_F305_Q0.8330.63
267_E285_I0.8310.63
262_A304_E0.8300.63
143_A204_N0.8260.63
5_T138_K0.8230.62
41_M77_L0.8220.62
201_E215_I0.8220.62
83_K275_L0.8210.62
289_D292_N0.8190.62
251_L282_A0.8180.62
255_D269_P0.8160.62
288_D292_N0.8150.62
47_I311_I0.8140.61
239_L247_I0.8130.61
160_R234_F0.8110.61
172_L253_E0.8100.61
270_L312_V0.8100.61
266_A297_R0.8080.61
250_L286_L0.8060.61
10_S304_E0.8050.61
122_I174_E0.8040.60
154_R213_A0.8020.60
203_I264_K0.7990.60
38_S95_E0.7980.60
150_D271_R0.7960.60
39_A43_N0.7940.60
278_M290_L0.7920.59
239_L250_L0.7910.59
271_R290_L0.7890.59
159_L232_E0.7890.59
8_D257_E0.7870.59
63_A328_D0.7840.59
253_E256_S0.7830.58
188_L218_V0.7820.58
167_V193_M0.7810.58
196_V232_E0.7730.57
139_R164_F0.7730.57
203_I288_D0.7710.57
62_E220_E0.7650.57
283_A289_D0.7650.57
252_Q277_N0.7640.57
208_T211_E0.7640.57
158_M210_Q0.7630.56
16_T289_D0.7620.56
249_R315_L0.7570.56
61_Q254_V0.7570.56
29_L132_T0.7550.56
106_G163_T0.7540.56
219_R293_R0.7510.55
129_I230_I0.7510.55
110_L137_L0.7500.55
90_A194_G0.7490.55
9_K55_V0.7490.55
244_D286_L0.7490.55
247_I289_D0.7480.55
38_S97_I0.7460.55
22_A84_A0.7460.55
19_E83_K0.7460.55
41_M80_V0.7450.55
204_N297_R0.7430.54
223_G302_E0.7420.54
211_E325_S0.7410.54
107_I195_G0.7390.54
5_T93_L0.7370.54
184_D312_V0.7340.54
203_I298_L0.7320.53
248_Q252_Q0.7310.53
247_I273_K0.7300.53
25_V140_A0.7290.53
22_A111_N0.7290.53
158_M203_I0.7260.53
274_F290_L0.7240.53
205_L238_N0.7220.52
156_D174_E0.7200.52
22_A90_A0.7200.52
275_L290_L0.7190.52
259_L279_S0.7170.52
118_A133_I0.7170.52
206_M214_V0.7160.52
134_L147_A0.7120.51
34_V222_D0.7070.51
72_N75_D0.7060.51
78_R98_L0.7060.51
161_I175_L0.7050.51
210_Q274_F0.7040.51
204_N234_F0.7030.50
252_Q259_L0.6990.50
110_L296_V0.6990.50
57_A206_M0.6980.50
93_L173_A0.6980.50
20_D24_E0.6960.50
31_Q112_F0.6950.50
93_L289_D0.6950.50
159_L222_D0.6940.50
22_A195_G0.6940.50
249_R256_S0.6910.49
63_A167_V0.6900.49
86_G195_G0.6880.49
306_K316_A0.6870.49
247_I267_E0.6870.49
83_K201_E0.6870.49
105_S178_V0.6850.49
44_V55_V0.6820.48
145_I183_L0.6800.48
14_L271_R0.6790.48
85_L200_A0.6770.48
136_H288_D0.6760.48
26_F70_N0.6750.48
15_M68_A0.6740.48
253_E318_T0.6740.48
239_L309_L0.6740.48
44_V134_L0.6730.47
90_A226_A0.6730.47
118_A129_I0.6720.47
5_T272_E0.6700.47
260_L324_G0.6680.47
72_N182_L0.6680.47
267_E298_L0.6670.47
37_L129_I0.6670.47
136_H183_L0.6660.47
161_I320_E0.6640.47
171_A174_E0.6640.47
230_I316_A0.6620.46
13_L160_R0.6620.46
15_M143_A0.6620.46
280_Q284_D0.6610.46
134_L142_A0.6600.46
118_A260_L0.6570.46
178_V182_L0.6560.46
227_Q328_D0.6550.46
9_K92_S0.6540.46
259_L282_A0.6490.45
244_D323_I0.6480.45
88_E92_S0.6480.45
29_L264_K0.6460.45
66_F76_Y0.6460.45
229_I273_K0.6460.45
165_G181_G0.6430.44
169_P313_R0.6430.44
33_E233_M0.6420.44
254_V274_F0.6380.44
55_V270_L0.6370.44
121_L215_I0.6370.44
113_M233_M0.6360.44
67_A220_E0.6330.43
67_A299_S0.6300.43
174_E203_I0.6290.43
228_K232_E0.6280.43
196_V284_D0.6280.43
137_L159_L0.6250.43
250_L254_V0.6240.43
23_A215_I0.6210.42
158_M218_V0.6210.42
31_Q235_L0.6210.42
38_S216_T0.6190.42
239_L280_Q0.6170.42
87_E91_A0.6150.42
165_G222_D0.6140.42
15_M189_K0.6130.41
123_R150_D0.6100.41
58_E238_N0.6100.41
242_V316_A0.6090.41
82_V170_A0.6090.41
191_S250_L0.6080.41
175_L200_A0.6080.41
30_S142_A0.6070.41
102_D267_E0.6030.40
201_E241_D0.6030.40
68_A318_T0.6020.40
6_G62_E0.6020.40
290_L301_V0.6010.40
35_Q109_T0.6000.40
121_L186_Q0.6000.40
90_A162_A0.5970.40
119_A130_I0.5960.40
132_T228_K0.5960.40
16_T52_L0.5950.40
261_I304_E0.5950.40
75_D156_D0.5940.40
80_V265_G0.5910.39
116_Q230_I0.5880.39
242_V312_V0.5880.39
202_I265_G0.5870.39
133_I175_L0.5860.39
243_D322_V0.5850.39
281_R301_V0.5850.39
63_A68_A0.5840.39
241_D328_D0.5810.38
75_D141_Q0.5800.38
154_R283_A0.5770.38
188_L309_L0.5760.38
99_E235_L0.5740.38
201_E229_I0.5740.38
59_F233_M0.5730.38
149_F170_A0.5720.38
88_E276_R0.5700.37
14_L45_T0.5700.37
301_V305_Q0.5690.37
13_L67_A0.5690.37
200_A203_I0.5680.37
128_Q315_L0.5680.37
25_V86_G0.5670.37
67_A70_N0.5660.37
249_R318_T0.5660.37
263_L328_D0.5650.37
47_I230_I0.5650.37
196_V237_E0.5650.37
101_R107_I0.5640.37
211_E218_V0.5630.37
138_K141_Q0.5630.37
217_A221_F0.5610.36
287_R314_R0.5610.36
162_A222_D0.5600.36
8_D69_L0.5590.36
94_L180_N0.5580.36
270_L327_E0.5560.36
141_Q284_D0.5560.36
61_Q142_A0.5560.36
164_F199_A0.5550.36
101_R123_R0.5550.36
114_E280_Q0.5530.36
77_L118_A0.5530.36
119_A124_D0.5530.36
9_K54_D0.5500.35
155_H183_L0.5480.35
26_F230_I0.5480.35
28_H108_E0.5440.35
7_T10_S0.5430.35
106_G176_T0.5430.35
122_I241_D0.5420.35
210_Q309_L0.5410.35
48_S243_D0.5400.35
182_L207_K0.5390.34
58_E240_V0.5390.34
247_I286_L0.5390.34
133_I223_G0.5380.34
12_I33_E0.5380.34
31_Q86_G0.5370.34
72_N81_L0.5360.34
147_A231_D0.5360.34
199_A300_Q0.5360.34
134_L145_I0.5340.34
15_M97_I0.5340.34
135_V232_E0.5330.34
61_Q314_R0.5320.34
162_A196_V0.5320.34
97_I239_L0.5310.34
21_R129_I0.5310.34
55_V58_E0.5300.34
80_V142_A0.5300.34
250_L270_L0.5300.34
99_E104_A0.5290.34
56_L94_L0.5290.34
118_A148_L0.5280.33
40_A316_A0.5260.33
151_E217_A0.5260.33
37_L42_A0.5250.33
12_I60_E0.5240.33
92_S124_D0.5240.33
36_T40_A0.5230.33
246_S321_M0.5230.33
128_Q233_M0.5220.33
114_E169_P0.5220.33
277_N288_D0.5160.32
55_V78_R0.5160.32
73_A133_I0.5160.32
204_N233_M0.5150.32
150_D298_L0.5150.32
60_E64_E0.5140.32
142_A202_I0.5140.32
197_R227_Q0.5130.32
132_T178_V0.5110.32
102_D118_A0.5080.32
12_I20_D0.5070.32
84_A225_L0.5070.32
105_S176_T0.5060.31
289_D310_L0.5060.31
275_L286_L0.5050.31
99_E122_I0.5050.31
160_R259_L0.5040.31
297_R301_V0.5040.31
182_L313_R0.5040.31
121_L188_L0.5030.31
19_E239_L0.5030.31
35_Q317_E0.5020.31
218_V285_I0.5020.31
58_E157_V0.5020.31
247_I257_E0.5010.31
19_E41_M0.5000.31
200_A204_N0.5000.31
127_P153_L0.5000.31
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3hjlA 1 0.9668 100 0.028 Contact Map
3uswA 1 0.6375 100 0.27 Contact Map
4fhrB 1 0.6284 100 0.414 Contact Map
4fq0C 1 0.2417 99.9 0.736 Contact Map
2zy9A 2 0.4683 96.7 0.922 Contact Map
2ouxA 2 0.5227 96 0.928 Contact Map
2yvyA 2 0.5136 94.8 0.933 Contact Map
4x2uA 1 0.5015 64.5 0.956 Contact Map
4qhpA 1 0.5015 63.2 0.956 Contact Map
3kxrA 3 0.2508 63.1 0.956 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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