GREMLIN Database
FLIL - Flagellar protein FliL
UniProt: P0ABX8 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10322
Length: 154 (145)
Sequences: 1411 (1146)
Seq/√Len: 95.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
29_S33_S3.5341.00
32_Y36_H3.4291.00
108_Q125_E3.2081.00
28_A32_Y2.6861.00
30_A34_Y2.5781.00
74_Y150_A2.3551.00
25_A29_S2.2681.00
84_E88_S2.2511.00
15_W19_L2.2281.00
99_S123_I2.2181.00
106_S119_K2.1641.00
22_I25_A2.1431.00
109_D112_V2.1371.00
80_R96_E2.1021.00
88_S91_S2.0701.00
57_Y81_L1.9431.00
26_A30_A1.9201.00
27_C31_G1.9111.00
101_L126_I1.8681.00
108_Q112_V1.8371.00
23_T26_A1.8361.00
79_L130_L1.7881.00
29_S32_Y1.7661.00
131_S141_Q1.7221.00
64_V73_L1.7101.00
85_A88_S1.6821.00
31_G35_W1.6271.00
87_R91_S1.5921.00
59_L98_R1.5251.00
14_L18_I1.5201.00
11_K14_L1.4751.00
24_L27_C1.4160.99
93_Y96_E1.4030.99
129_T132_T1.4000.99
9_K13_S1.3980.99
22_I26_A1.3930.99
104_L126_I1.3830.99
11_K15_W1.3760.99
127_K146_V1.3430.99
105_F126_I1.3430.99
12_R16_I1.3200.99
60_D98_R1.3160.99
66_L99_S1.2770.99
89_R141_Q1.2760.99
34_Y38_H1.2720.99
18_I25_A1.2550.99
62_F98_R1.2510.99
101_L105_F1.2310.99
16_I20_V1.2210.98
68_D71_R1.2150.98
59_L97_V1.2020.98
148_Y151_F1.2010.98
134_L141_Q1.1960.98
99_S103_L1.1940.98
27_C30_A1.1860.98
33_S37_S1.1670.98
63_T74_Y1.1330.97
77_I126_I1.1260.97
30_A33_S1.1250.97
84_E87_R1.1170.97
13_S18_I1.1080.97
73_L105_F1.0900.97
88_S92_E1.0850.97
58_A78_T1.0800.97
56_F93_Y1.0700.96
7_S10_S1.0650.96
113_L153_L1.0650.96
10_S13_S1.0640.96
12_R19_L1.0430.96
10_S15_W1.0410.96
98_R102_L1.0410.96
13_S16_I1.0330.96
77_I148_Y1.0300.96
6_I19_L1.0210.95
131_S134_L0.9990.95
6_I9_K0.9910.95
80_R144_T0.9890.94
96_E147_L0.9830.94
124_A128_T0.9780.94
24_L28_A0.9590.93
57_Y87_R0.9550.93
20_V27_C0.9480.93
64_V105_F0.9450.93
17_P20_V0.9430.93
12_R15_W0.9400.93
116_E120_K0.9370.93
149_T152_I0.9280.92
17_P21_F0.9230.92
115_T118_G0.9140.92
18_I21_F0.9050.91
120_K123_I0.9040.91
91_S94_L0.9040.91
126_I130_L0.9020.91
19_L22_I0.8990.91
104_L108_Q0.8940.91
9_K12_R0.8860.90
82_K144_T0.8810.90
21_F25_A0.8770.90
76_G150_A0.8760.90
119_K151_F0.8680.90
106_S115_T0.8660.89
57_Y91_S0.8650.89
16_I19_L0.8630.89
97_V130_L0.8610.89
13_S17_P0.8580.89
81_L95_P0.8550.89
56_F95_P0.8510.89
57_Y94_L0.8420.88
19_L23_T0.8370.88
73_L114_A0.8340.88
46_A49_R0.8200.87
112_V146_V0.8190.87
56_F147_L0.8170.87
57_Y90_L0.8140.86
54_P93_Y0.8080.86
28_A31_G0.8070.86
61_T74_Y0.8030.86
86_T89_R0.7950.85
72_V121_N0.7850.84
45_K49_R0.7830.84
26_A32_Y0.7820.84
71_R110_A0.7790.84
100_R129_T0.7710.83
80_R145_D0.7680.83
71_R152_I0.7610.82
89_R93_Y0.7600.82
103_L119_K0.7600.82
54_P80_R0.7360.80
23_T27_C0.7340.80
31_G36_H0.7270.79
31_G34_Y0.7260.79
61_T73_L0.7230.79
62_F101_L0.7220.79
21_F28_A0.7160.78
102_L106_S0.7120.78
126_I146_V0.7100.78
118_G148_Y0.6990.77
100_R133_P0.6960.76
74_Y152_I0.6930.76
20_V23_T0.6880.76
32_Y35_W0.6800.75
44_D48_Q0.6790.75
6_I11_K0.6740.74
32_Y37_S0.6700.74
76_G99_S0.6690.74
107_R116_E0.6680.73
14_L22_I0.6620.73
55_V84_E0.6610.73
121_N124_A0.6610.73
66_L70_D0.6550.72
150_A153_L0.6530.72
47_Q50_V0.6510.72
35_W38_H0.6510.72
59_L94_L0.6490.71
61_T76_G0.6450.71
128_T132_T0.6450.71
121_N125_E0.6430.71
29_S36_H0.6410.70
117_E120_K0.6400.70
110_A114_A0.6290.69
41_A44_D0.6280.69
22_I29_S0.6260.69
55_V87_R0.6250.68
101_L134_L0.6230.68
58_A76_G0.6230.68
68_D109_D0.6200.68
81_L86_T0.6190.68
28_A35_W0.6190.68
123_I147_L0.6170.67
120_K127_K0.6130.67
124_A127_K0.6090.66
14_L30_A0.6070.66
8_K11_K0.6070.66
66_L80_R0.6040.66
120_K124_A0.6040.66
19_L27_C0.6030.66
99_S102_L0.5980.65
118_G151_F0.5960.65
75_I148_Y0.5900.64
10_S18_I0.5850.63
78_T149_T0.5820.63
62_F74_Y0.5790.63
56_F78_T0.5740.62
104_L122_L0.5710.62
73_L108_Q0.5680.61
20_V24_L0.5670.61
83_D86_T0.5650.61
48_Q51_V0.5630.60
65_N147_L0.5600.60
54_P74_Y0.5600.60
66_L153_L0.5550.59
33_S36_H0.5550.59
56_F96_E0.5530.59
10_S16_I0.5520.59
82_K101_L0.5510.59
39_Q42_A0.5490.59
19_L35_W0.5490.59
19_L91_S0.5480.58
15_W18_I0.5470.58
80_R99_S0.5470.58
21_F33_S0.5440.58
7_S12_R0.5440.58
15_W32_Y0.5390.57
36_H41_A0.5380.57
75_I151_F0.5370.57
15_W128_T0.5290.56
115_T146_V0.5280.56
66_L69_A0.5270.55
103_L120_K0.5260.55
126_I149_T0.5250.55
38_H41_A0.5240.55
72_V153_L0.5210.55
89_R142_D0.5150.54
25_A34_Y0.5110.53
37_S41_A0.5100.53
107_R115_T0.5060.53
104_L125_E0.5010.52
22_I50_V0.5000.52
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ne5B 3 0.4091 56.9 0.909 Contact Map
3j6da 3 0 45 0.915 Contact Map
2mfrA 1 0.3377 37.2 0.919 Contact Map
3zg1A 2 0.5195 34.3 0.92 Contact Map
2m8rA 1 0.2403 28.4 0.924 Contact Map
3vmtA 1 0.8117 17.8 0.93 Contact Map
3bk6A 3 0.6948 16.4 0.932 Contact Map
4dvyP 1 0.461 14.1 0.933 Contact Map
2rpbA 1 0.7143 13.4 0.934 Contact Map
3owqA 1 0.487 12.6 0.935 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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