GREMLIN Database
FLGG - Flagellar basal-body rod protein FlgG
UniProt: P0ABX5 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14271
Length: 260 (243)
Sequences: 6655 (5164)
Seq/√Len: 331.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
103_F120_F3.4211.00
152_G156_V3.2841.00
95_V151_I3.1831.00
123_D127_Q3.0481.00
187_I193_T2.9611.00
130_T134_F2.9121.00
159_V170_V2.9011.00
114_Y178_F2.8801.00
86_L218_Y2.8481.00
127_Q135_Q2.8181.00
86_L96_A2.6161.00
104_Q176_T2.5211.00
100_Q177_T2.5181.00
36_R229_E2.4131.00
4_S250_T2.4101.00
185_E193_T2.2641.00
215_Y218_Y2.2041.00
19_M233_M2.1861.00
14_A72_V2.1721.00
107_L113_A2.1571.00
252_Q255_Q2.1131.00
11_G243_N2.1001.00
26_L226_V2.0561.00
18_N236_V2.0251.00
245_K248_S2.0181.00
81_H102_F1.9951.00
37_Q186_S1.9721.00
194_E200_A1.9561.00
140_I143_P1.9471.00
87_S221_T1.9401.00
156_V169_Q1.9261.00
185_E195_T1.9261.00
141_T144_A1.8691.00
107_L111_S1.8261.00
232_N235_Q1.8041.00
140_I144_A1.7961.00
22_I236_V1.7901.00
123_D129_V1.7891.00
113_A187_I1.7731.00
15_Q239_A1.7461.00
113_A191_L1.7391.00
180_N183_G1.7321.00
228_E232_N1.7281.00
18_N232_N1.7121.00
88_Q218_Y1.7121.00
95_V214_L1.7041.00
225_N228_E1.6971.00
19_M236_V1.6621.00
105_V115_T1.6351.00
98_K215_Y1.5931.00
188_G192_Y1.5901.00
21_V39_A1.5611.00
38_R80_L1.5551.00
238_R241_E1.5471.00
38_R78_E1.5381.00
8_A246_A1.5221.00
97_I175_L1.5211.00
176_T203_E1.5121.00
152_G158_S1.4981.00
40_V76_A1.4911.00
22_I233_M1.4821.00
107_L134_F1.4541.00
229_E232_N1.4451.00
89_T94_D1.4341.00
36_R228_E1.4341.00
97_I212_G1.4291.00
120_F136_V1.4261.00
158_S169_Q1.4031.00
117_D190_N1.4011.00
172_Q205_T1.3971.00
37_Q79_R1.3961.00
108_P134_F1.3951.00
41_F45_L1.3921.00
128_L136_V1.3821.00
93_K149_I1.3821.00
105_V130_T1.3621.00
161_Q164_Q1.3611.00
143_P146_A1.3611.00
100_Q181_D1.3481.00
104_Q112_S1.3451.00
146_A159_V1.3241.00
36_R80_L1.3211.00
29_V226_V1.3201.00
248_S251_D1.3171.00
85_N221_T1.3081.00
153_R213_L1.2971.00
79_R186_S1.2941.00
39_A74_P1.2861.00
140_I146_A1.2841.00
40_V78_E1.2801.00
106_M137_Q1.2681.00
32_N219_V1.2621.00
91_N94_D1.2451.00
32_N117_D1.2131.00
95_V103_F1.2081.00
16_Q20_D1.2051.00
34_F37_Q1.1971.00
98_K101_G1.1831.00
178_F194_E1.1711.00
17_T74_P1.1601.00
41_F72_V1.1491.00
207_G213_L1.1491.00
95_V173_L1.1491.00
24_N34_F1.1271.00
15_Q18_N1.1191.00
117_D131_A1.1161.00
139_A172_Q1.1151.00
187_I191_L1.1121.00
93_K128_L1.1061.00
147_L162_Q1.1041.00
105_V113_A1.0971.00
32_N119_S1.0961.00
156_V172_Q1.0891.00
8_A247_V1.0851.00
43_D46_Y1.0801.00
151_I157_V1.0791.00
42_E75_V1.0761.00
113_A193_T1.0731.00
19_M253_M1.0691.00
177_T211_A1.0591.00
198_S201_P1.0481.00
254_L258_T1.0461.00
194_E198_S1.0451.00
138_P174_N1.0421.00
48_T51_Q1.0381.00
11_G15_Q1.0251.00
130_T136_V1.0131.00
97_I101_G1.0121.00
134_F191_L1.0021.00
42_E73_R0.9951.00
25_N229_E0.9831.00
183_G195_T0.9671.00
105_V120_F0.9591.00
44_L48_T0.9571.00
251_D254_L0.9571.00
22_I229_E0.9551.00
14_A41_F0.9521.00
238_R251_D0.9451.00
142_I146_A0.9321.00
15_Q236_V0.9191.00
224_V229_E0.9171.00
164_Q167_P0.9161.00
71_G74_P0.9141.00
41_F44_L0.9101.00
188_G195_T0.9081.00
91_N121_Q0.9061.00
178_F184_L0.9051.00
103_F173_L0.8971.00
160_T167_P0.8971.00
6_W10_T0.8881.00
93_K122_V0.8851.00
104_Q203_E0.8761.00
187_I192_Y0.8761.00
15_Q41_F0.8751.00
23_A246_A0.8721.00
18_N22_I0.8671.00
250_T253_M0.8611.00
132_G189_E0.8601.00
9_K12_L0.8601.00
96_A218_Y0.8551.00
175_L211_A0.8511.00
161_Q168_V0.8421.00
192_Y195_T0.8401.00
98_K213_L0.8371.00
19_M237_Q0.8301.00
153_R215_Y0.8291.00
161_Q165_A0.8201.00
136_V173_L0.8201.00
106_M135_Q0.8161.00
67_Q186_S0.8141.00
95_V216_Q0.8101.00
148_S160_T0.8041.00
17_T20_D0.7911.00
115_T118_G0.7901.00
101_G105_V0.7891.00
138_P171_G0.7831.00
161_Q166_A0.7811.00
6_W9_K0.7781.00
21_V34_F0.7701.00
158_S167_P0.7681.00
186_S192_Y0.7541.00
114_Y201_P0.7520.99
104_Q174_N0.7490.99
195_T199_G0.7490.99
225_N230_L0.7470.99
3_S70_T0.7470.99
8_A243_N0.7460.99
195_T198_S0.7450.99
171_G174_N0.7370.99
102_F181_D0.7360.99
168_V171_G0.7360.99
119_S131_A0.7360.99
169_Q172_Q0.7350.99
14_A74_P0.7340.99
205_T208_L0.7330.99
197_S200_A0.7320.99
121_Q131_A0.7310.99
175_L212_G0.7290.99
249_T252_Q0.7140.99
12_L244_S0.7140.99
18_N235_Q0.7100.99
249_T253_M0.7090.99
164_Q169_Q0.7010.99
24_N37_Q0.7010.99
95_V120_F0.6990.99
97_I102_F0.6940.99
117_D120_F0.6930.99
126_G133_G0.6900.99
92_S148_S0.6880.99
46_Y69_G0.6880.99
47_Q70_T0.6860.99
105_V191_L0.6850.99
22_I232_N0.6850.99
97_I103_F0.6840.99
251_D255_Q0.6820.99
129_V135_Q0.6800.99
123_D126_G0.6800.99
130_T191_L0.6760.99
176_T179_M0.6740.99
21_V77_T0.6710.99
240_Y244_S0.6690.99
184_L188_G0.6680.99
141_T146_A0.6650.99
229_E237_Q0.6610.99
4_S246_A0.6580.99
121_Q124_Q0.6560.99
139_A166_A0.6540.99
227_A230_L0.6540.99
12_L15_Q0.6520.99
173_L176_T0.6500.99
81_H192_Y0.6490.99
5_L11_G0.6470.98
116_R120_F0.6460.98
110_G113_A0.6450.98
69_G77_T0.6440.98
144_A164_Q0.6410.98
215_Y219_V0.6400.98
237_Q244_S0.6380.98
86_L215_Y0.6350.98
13_D17_T0.6350.98
230_L246_A0.6350.98
196_Q200_A0.6340.98
230_L256_K0.6310.98
144_A162_Q0.6310.98
172_Q178_F0.6250.98
207_G210_G0.6220.98
248_S252_Q0.6200.98
177_T181_D0.6200.98
246_A250_T0.6190.98
162_Q165_A0.6180.98
42_E45_L0.6170.98
16_Q240_Y0.6170.98
231_V235_Q0.6160.98
150_T160_T0.6140.98
69_G74_P0.6130.98
179_M182_T0.6110.98
114_Y118_G0.6090.98
208_L212_G0.6080.98
243_N246_A0.6080.98
207_G211_A0.6080.98
219_V223_N0.6080.98
18_N41_F0.6080.98
196_Q199_G0.6040.98
187_I190_N0.6040.98
188_G191_L0.6040.98
147_L160_T0.5990.97
234_I237_Q0.5960.97
188_G193_T0.5960.97
89_T97_I0.5940.97
13_D225_N0.5920.97
118_G126_G0.5890.97
7_I20_D0.5880.97
239_A243_N0.5880.97
174_N179_M0.5830.97
183_G199_G0.5810.97
105_V134_F0.5810.97
230_L248_S0.5810.97
248_S255_Q0.5810.97
7_I71_G0.5760.97
98_K102_F0.5760.97
35_K84_G0.5750.97
106_M110_G0.5750.97
194_E199_G0.5740.97
184_L187_I0.5720.97
32_N221_T0.5710.97
115_T130_T0.5710.97
40_V44_L0.5710.97
84_G89_T0.5680.97
5_L9_K0.5680.97
178_F199_G0.5660.96
247_V251_D0.5650.96
38_R41_F0.5630.96
46_Y49_I0.5630.96
81_H84_G0.5630.96
122_V128_L0.5620.96
17_T21_V0.5600.96
21_V74_P0.5600.96
227_A235_Q0.5590.96
115_T120_F0.5580.96
171_G176_T0.5560.96
206_P210_G0.5550.96
171_G175_L0.5540.96
94_D97_I0.5530.96
89_T96_A0.5520.96
28_N31_T0.5520.96
178_F201_P0.5510.96
35_K220_E0.5510.96
139_A164_Q0.5500.96
101_G212_G0.5490.96
241_E244_S0.5460.96
164_Q168_V0.5460.96
101_G106_M0.5450.96
149_I159_V0.5440.96
49_I53_G0.5440.96
123_D135_Q0.5440.96
106_M112_S0.5420.96
207_G212_G0.5410.95
14_A22_I0.5400.95
168_V172_Q0.5390.95
141_T166_A0.5370.95
111_S193_T0.5370.95
12_L71_G0.5360.95
226_V241_E0.5350.95
168_V200_A0.5340.95
118_G133_G0.5310.95
107_L110_G0.5310.95
99_G103_F0.5300.95
39_A77_T0.5300.95
146_A149_I0.5300.95
226_V242_I0.5300.95
114_Y133_G0.5290.95
48_T67_Q0.5280.95
25_N34_F0.5260.95
153_R157_V0.5250.95
146_A162_Q0.5230.95
192_Y196_Q0.5220.95
255_Q258_T0.5210.94
18_N39_A0.5190.94
164_Q171_G0.5190.94
10_T14_A0.5170.94
8_A250_T0.5160.94
44_L70_T0.5150.94
103_F116_R0.5150.94
118_G219_V0.5140.94
8_A11_G0.5130.94
184_L192_Y0.5120.94
43_D69_G0.5110.94
36_R223_N0.5110.94
233_M237_Q0.5100.94
177_T202_N0.5100.94
189_E193_T0.5080.94
252_Q258_T0.5080.94
19_M22_I0.5070.94
44_L50_R0.5070.94
157_V171_G0.5070.94
32_N87_S0.5060.94
168_V178_F0.5060.94
3_S7_I0.5050.94
174_N178_F0.5030.93
243_N247_V0.5030.93
44_L47_Q0.5020.93
95_V217_G0.5000.93
33_G192_Y0.5000.93
74_P77_T0.5000.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3a69A 3 0.7038 100 0.088 Contact Map
4ut1A 1 0.5038 99.9 0.597 Contact Map
1wlgA 2 0.5 99.8 0.641 Contact Map
2d4yA 1 0.7808 96.5 0.882 Contact Map
1oryB 2 0.1462 44.1 0.939 Contact Map
3flvA 1 0.1038 6.9 0.959 Contact Map
3txsA 5 0.3077 3.7 0.964 Contact Map
2ca5A 1 0.2308 2.9 0.966 Contact Map
2m4eA 1 0.0654 2.3 0.968 Contact Map
1n0wB 1 0.1038 2.2 0.968 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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