GREMLIN Database
YFAE - Uncharacterized ferredoxin-like protein YfaE
UniProt: P0ABW3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12360
Length: 84 (74)
Sequences: 309 (201)
Seq/√Len: 23.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
51_A81_E2.3900.98
56_W60_P2.0580.95
21_S24_A2.0570.95
60_P73_C2.0450.95
59_E75_R1.9890.94
20_P28_S1.9530.93
55_D75_R1.8940.92
26_L36_Q1.8400.91
53_Q77_K1.8380.91
36_Q44_S1.8210.90
69_I74_C1.8140.90
71_P74_C1.7200.88
57_I75_R1.6630.86
47_T74_C1.6560.85
27_E38_R1.6410.85
24_A27_E1.5370.81
53_Q78_G1.4970.79
20_P25_A1.4760.78
48_R83_E1.4680.78
48_R67_G1.4590.77
28_S31_V1.4580.77
51_A78_G1.4500.77
20_P24_A1.4370.76
41_Y61_L1.4030.74
10_G13_L1.3230.70
36_Q46_R1.2970.68
25_A29_H1.2470.65
55_D77_K1.2360.64
27_E52_G1.2270.64
46_R68_E1.1650.60
17_D65_Q1.1350.58
12_Q50_V1.1340.57
41_Y73_C1.1050.55
50_V81_E1.0840.54
31_V71_P1.0670.53
46_R64_I1.0580.52
21_S57_I1.0510.52
20_P30_N1.0460.51
69_I82_I1.0270.50
39_E66_P1.0080.49
32_A50_V1.0020.48
60_P71_P0.9940.48
13_L17_D0.9870.47
30_N50_V0.9550.45
49_L82_I0.9550.45
30_N62_A0.9520.45
22_L74_C0.9480.45
44_S65_Q0.9440.44
47_T69_I0.9270.43
29_H41_Y0.9170.42
48_R53_Q0.8890.40
53_Q57_I0.8840.40
15_C76_A0.8620.39
28_S82_I0.8490.38
33_V71_P0.8330.37
34_E83_E0.8290.36
34_E47_T0.8250.36
44_S74_C0.8140.36
18_E33_V0.8040.35
25_A71_P0.7950.34
12_Q48_R0.7940.34
43_G46_R0.7930.34
10_G81_E0.7870.34
58_A80_I0.7860.34
34_E54_V0.7760.33
46_R62_A0.7630.32
58_A76_A0.7430.31
43_G68_E0.7350.31
36_Q62_A0.7270.30
12_Q30_N0.7260.30
36_Q60_P0.7240.30
14_L24_A0.7120.29
36_Q41_Y0.7110.29
57_I64_I0.6990.29
26_L73_C0.6990.29
49_L67_G0.6980.28
47_T71_P0.6930.28
75_R81_E0.6890.28
49_L69_I0.6870.28
20_P39_E0.6850.28
32_A66_P0.6830.28
24_A38_R0.6750.27
41_Y44_S0.6750.27
56_W74_C0.6730.27
51_A54_V0.6680.27
59_E76_A0.6660.27
14_L68_E0.6590.26
22_L80_I0.6580.26
35_Y54_V0.6430.25
16_Q67_G0.6430.25
22_L50_V0.6400.25
14_L67_G0.6310.25
35_Y46_R0.6290.25
18_E78_G0.6270.25
41_Y74_C0.6160.24
29_H33_V0.6130.24
26_L80_I0.6120.24
47_T57_I0.6060.23
10_G83_E0.5910.23
53_Q61_L0.5760.22
34_E62_A0.5710.22
49_L76_A0.5700.22
61_L81_E0.5580.21
18_E77_K0.5460.21
27_E79_D0.5340.20
33_V60_P0.5290.20
66_P76_A0.5140.19
41_Y60_P0.5110.19
39_E59_E0.5100.19
39_E44_S0.5030.19
10_G14_L0.5000.19
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2piaA 1 0.9881 99.5 0.573 Contact Map
3zyyX 2 0.9881 99.5 0.576 Contact Map
4n58A 4 0.9524 99.5 0.582 Contact Map
4itkA 1 1 99.5 0.584 Contact Map
3huiA 1 1 99.5 0.586 Contact Map
3wcqA 1 1 99.5 0.589 Contact Map
1doiA 5 1 99.5 0.591 Contact Map
3ah7A 2 0.9881 99.5 0.595 Contact Map
2y5cA 1 1 99.5 0.595 Contact Map
2mj3A 1 1 99.5 0.596 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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