GREMLIN Database
YCHF - Ribosome-binding ATPase YchF
UniProt: P0ABU2 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11404
Length: 363 (358)
Sequences: 3388 (1589)
Seq/√Len: 84.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
118_K123_D4.9411.00
351_V357_M4.4961.00
303_Q313_E3.6301.00
53_Q56_E3.5861.00
60_P290_V3.2861.00
171_Q181_L3.0591.00
55_A63_T3.0281.00
122_A225_I3.0131.00
332_G335_G2.9161.00
148_Q166_E2.8741.00
344_A360_L2.7241.00
125_I222_V2.6791.00
116_S127_V2.6401.00
144_I162_L2.5971.00
254_E258_E2.5781.00
167_K187_E2.5581.00
53_Q328_I2.5541.00
209_N212_G2.4941.00
137_L169_L2.4781.00
108_E218_Y2.4021.00
169_L173_E2.3691.00
295_I299_A2.3471.00
61_Q288_K2.3431.00
61_Q287_V2.2871.00
264_P267_N2.2661.00
168_C178_L2.2271.00
28_E35_C2.1991.00
321_T357_M2.1971.00
280_Q297_V2.1961.00
324_F328_I2.1591.00
330_Y339_A2.1401.00
224_E228_K2.1081.00
321_T351_V2.0771.00
322_I336_A2.0731.00
263_E271_R2.0621.00
18_L238_A2.0411.00
170_P174_N2.0211.00
232_V275_K2.0151.00
5_C273_G2.0131.00
178_L199_L1.9891.00
335_G339_A1.9881.00
296_P299_A1.9671.00
320_Q360_L1.9601.00
337_K342_M1.9561.00
295_I304_A1.9341.00
285_A290_V1.9241.00
116_S123_D1.8811.00
315_G361_F1.8781.00
275_K297_V1.8761.00
101_G205_I1.8741.00
53_Q324_F1.8381.00
299_A303_Q1.8311.00
102_H202_T1.8051.00
335_G338_E1.8001.00
171_Q180_A1.8001.00
318_R360_L1.7901.00
78_K116_S1.7841.00
163_A166_E1.7621.00
219_L235_P1.7561.00
322_I333_E1.7391.00
325_E329_T1.7341.00
58_V290_V1.7341.00
120_N123_D1.7321.00
184_S187_E1.7261.00
24_K252_R1.7101.00
58_V285_A1.7061.00
318_R344_A1.6901.00
300_T350_I1.6691.00
232_V272_A1.6571.00
330_Y336_A1.6501.00
56_E59_K1.6441.00
140_C165_L1.6221.00
221_Q224_E1.6181.00
224_E227_A1.6151.00
145_H148_Q1.6011.00
135_A139_T1.5871.00
203_M276_L1.5871.00
104_V125_I1.5871.00
278_N297_V1.5601.00
334_Q337_K1.5541.00
220_D223_R1.5541.00
166_E170_P1.5491.00
120_N221_Q1.5461.00
217_P220_D1.5401.00
122_A221_Q1.5191.00
220_D224_E1.5110.99
218_Y221_Q1.4990.99
178_L196_F1.4950.99
143_A161_E1.4900.99
24_K249_D1.4810.99
326_D329_T1.4760.99
159_K163_A1.4750.99
333_E342_M1.4700.99
223_R227_A1.4700.99
106_C222_V1.4670.99
140_C169_L1.4490.99
331_K335_G1.4290.99
330_Y341_K1.4210.99
297_V352_K1.4110.99
205_I269_V1.4080.99
253_D257_Q1.4060.99
47_P270_I1.4060.99
54_L356_V1.4000.99
322_I342_M1.3910.99
306_G313_E1.3860.99
329_T341_K1.3790.99
176_G228_K1.3750.99
78_K127_V1.3690.99
215_N219_L1.3510.99
271_R275_K1.3470.99
336_A342_M1.3390.99
109_N239_A1.3370.99
52_D56_E1.3280.99
147_V162_L1.3240.99
280_Q299_A1.3160.99
178_L181_L1.3150.99
323_S352_K1.3040.98
244_I255_F1.3000.98
130_T134_L1.2990.98
280_Q295_I1.2880.98
320_Q358_N1.2590.98
170_P173_E1.2520.98
125_I225_I1.2390.98
215_N220_D1.2370.98
342_M358_N1.2250.98
326_D341_K1.2060.97
58_V327_F1.1900.97
164_V190_A1.1820.97
51_L65_P1.1810.97
215_N235_P1.1770.97
255_F258_E1.1690.97
295_I307_K1.1610.97
242_A246_E1.1590.97
213_F219_L1.1510.97
59_K287_V1.1420.96
321_T344_A1.1390.96
92_T96_E1.1370.96
208_V235_P1.1350.96
219_L223_R1.1320.96
206_A222_V1.1270.96
272_A275_K1.1180.96
281_T292_A1.1150.96
282_Y307_K1.1110.96
162_L166_E1.1100.96
8_V100_I1.1070.96
325_E352_K1.1070.96
144_I165_L1.1020.96
155_D159_K1.0970.96
327_F332_G1.0970.96
312_F359_F1.0920.95
53_Q57_I1.0880.95
325_E328_I1.0850.95
239_A242_A1.0820.95
52_D63_T1.0810.95
302_P313_E1.0810.95
164_V167_K1.0750.95
323_S326_D1.0740.95
51_L55_A1.0690.95
168_C191_I1.0640.95
141_E169_L1.0630.95
327_F356_V1.0610.95
27_I30_A1.0480.94
4_K69_E1.0470.94
240_V259_L1.0450.94
212_G216_N1.0440.94
282_Y288_K1.0420.94
333_E358_N1.0380.94
242_A245_A1.0350.94
171_Q176_G1.0270.94
299_A307_K1.0270.94
146_R150_K1.0220.93
30_A35_C1.0200.93
320_Q344_A1.0170.93
144_I166_E1.0100.93
106_C206_A1.0080.93
5_C101_G1.0050.93
37_I74_A0.9920.92
188_K199_L0.9910.92
83_G87_G0.9890.92
310_T314_K0.9870.92
322_I327_F0.9780.92
239_A243_D0.9780.92
206_A233_V0.9620.91
332_G336_A0.9610.91
274_Y294_T0.9510.91
20_N29_A0.9480.91
27_I40_N0.9470.91
68_M273_G0.9440.90
330_Y335_G0.9390.90
323_S343_R0.9370.90
226_A233_V0.9340.90
55_A290_V0.9340.90
166_E169_L0.9280.90
176_G180_A0.9270.90
186_E189_A0.9270.90
60_P287_V0.9270.90
304_A351_V0.9210.89
50_R283_F0.9170.89
177_M198_T0.9110.89
46_M50_R0.9110.89
51_L63_T0.9100.89
223_R233_V0.9090.89
344_A358_N0.9070.89
328_I332_G0.9060.89
78_K82_K0.9060.89
315_G362_N0.9050.88
20_N27_I0.9000.88
17_T238_A0.8980.88
336_A356_V0.8960.88
171_Q174_N0.8920.88
244_I261_L0.8830.87
227_A230_G0.8800.87
348_D360_L0.8790.87
54_L285_A0.8780.87
43_V69_E0.8770.87
179_R229_E0.8720.87
165_L169_L0.8700.86
225_I228_K0.8700.86
327_F336_A0.8600.86
129_N229_E0.8560.86
147_V165_L0.8540.85
93_N97_T0.8530.85
164_V183_L0.8510.85
160_A164_V0.8490.85
71_V154_G0.8480.85
236_V269_V0.8470.85
314_K361_F0.8450.85
68_M97_T0.8430.85
183_L191_I0.8400.84
147_V161_E0.8390.84
191_I199_L0.8380.84
217_P221_Q0.8370.84
307_K312_F0.8370.84
4_K97_T0.8350.84
58_V288_K0.8340.84
102_H124_D0.8300.84
288_K310_T0.8280.84
300_T348_D0.8240.83
263_E267_N0.8240.83
183_L187_E0.8210.83
80_A83_G0.8120.82
80_A85_G0.8120.82
257_Q262_E0.8110.82
32_F35_C0.8060.82
300_T303_Q0.8030.82
164_V191_I0.7970.81
151_A157_D0.7960.81
58_V283_F0.7960.81
37_I77_V0.7890.81
301_A316_F0.7890.81
62_R288_K0.7860.80
323_S330_Y0.7850.80
154_G157_D0.7850.80
333_E337_K0.7850.80
219_L233_V0.7810.80
139_T142_R0.7790.80
208_V213_F0.7790.80
108_E217_P0.7740.79
159_K162_L0.7730.79
155_D158_A0.7700.79
144_I169_L0.7700.79
322_I358_N0.7690.79
185_A188_K0.7650.78
49_P53_Q0.7650.78
89_Q142_R0.7630.78
167_K170_P0.7620.78
57_I328_I0.7620.78
208_V219_L0.7610.78
302_P312_F0.7610.78
168_C171_Q0.7610.78
191_I194_L0.7600.78
324_F356_V0.7600.78
18_L236_V0.7600.78
237_C240_V0.7590.78
314_K362_N0.7590.78
151_A162_L0.7540.77
4_K71_V0.7530.77
288_K358_N0.7530.77
70_F101_G0.7500.77
161_E193_Y0.7490.77
326_D333_E0.7480.77
89_Q138_D0.7480.77
154_G159_K0.7450.77
139_T195_S0.7420.76
299_A304_A0.7410.76
154_G158_A0.7410.76
123_D127_V0.7400.76
333_E341_K0.7390.76
282_Y296_P0.7380.76
323_S336_A0.7340.76
164_V181_L0.7330.75
101_G203_M0.7330.75
61_Q64_L0.7310.75
300_T313_E0.7300.75
183_L193_Y0.7300.75
29_A35_C0.7290.75
140_C196_F0.7270.75
334_Q338_E0.7270.75
28_E32_F0.7240.75
104_V128_I0.7230.74
130_T173_E0.7230.74
306_G310_T0.7220.74
137_L140_C0.7210.74
94_I100_I0.7210.74
167_K183_L0.7200.74
280_Q304_A0.7180.74
55_A60_P0.7180.74
63_T288_K0.7170.74
167_K182_D0.7160.74
255_F259_L0.7150.74
99_A276_L0.7120.73
167_K181_L0.7120.73
43_V67_T0.7120.73
272_A276_L0.7110.73
58_V64_L0.7110.73
205_I236_V0.7050.73
66_T274_Y0.7040.72
126_E175_A0.7020.72
254_E257_Q0.7010.72
287_V333_E0.7000.72
80_A87_G0.6990.72
57_I327_F0.6990.72
58_V61_Q0.6970.72
70_F266_L0.6970.72
193_Y196_F0.6960.72
312_F358_N0.6940.71
27_I35_C0.6930.71
164_V194_L0.6900.71
20_N26_G0.6870.71
282_Y312_F0.6870.71
9_G14_G0.6850.70
232_V235_P0.6840.70
140_C144_I0.6840.70
49_P262_E0.6820.70
168_C181_L0.6760.69
216_N219_L0.6750.69
213_F235_P0.6750.69
113_I213_F0.6740.69
163_A170_P0.6730.69
72_D75_G0.6710.69
295_I303_Q0.6690.69
80_A90_F0.6670.68
253_D258_E0.6670.68
226_A230_G0.6660.68
122_A126_E0.6650.68
140_C172_L0.6640.68
12_N16_S0.6640.68
60_P64_L0.6630.68
38_E89_Q0.6600.68
122_A125_I0.6600.68
93_N197_L0.6590.67
54_L58_V0.6580.67
114_H117_G0.6550.67
285_A356_V0.6540.67
327_F335_G0.6520.67
25_A43_V0.6510.67
4_K96_E0.6480.66
49_P271_R0.6460.66
114_H119_V0.6460.66
160_A190_A0.6420.65
282_Y287_V0.6420.65
64_L291_R0.6410.65
73_I94_I0.6400.65
190_A194_L0.6380.65
225_I229_E0.6370.65
256_M261_L0.6350.65
106_C216_N0.6350.65
192_R195_S0.6350.65
213_F268_R0.6310.64
64_L287_V0.6310.64
133_A172_L0.6300.64
148_Q162_L0.6300.64
251_E255_F0.6290.64
54_L57_I0.6280.64
47_P65_P0.6260.64
87_G90_F0.6250.63
41_T69_E0.6240.63
168_C183_L0.6240.63
223_R235_P0.6240.63
303_Q306_G0.6230.63
34_F77_V0.6230.63
126_E130_T0.6220.63
33_P37_I0.6220.63
5_C161_E0.6210.63
5_C68_M0.6200.63
205_I212_G0.6200.63
58_V322_I0.6200.63
119_V124_D0.6190.63
57_I332_G0.6190.63
61_Q290_V0.6160.62
95_R135_A0.6150.62
218_Y222_V0.6150.62
86_L89_Q0.6150.62
274_Y281_T0.6140.62
319_A357_M0.6140.62
129_N225_I0.6130.62
147_V150_K0.6130.62
51_L288_K0.6130.62
71_V98_E0.6100.62
327_F330_Y0.6100.62
12_N31_N0.6080.61
5_C281_T0.6070.61
295_I351_V0.6060.61
163_A167_K0.6040.61
53_Q60_P0.6040.61
18_L22_L0.6040.61
60_P283_F0.6030.61
250_E254_E0.6030.61
56_E331_K0.6030.61
89_Q96_E0.6000.60
221_Q225_I0.5990.60
104_V129_N0.5990.60
58_V358_N0.5980.60
83_G88_N0.5980.60
244_I252_R0.5980.60
66_T281_T0.5980.60
33_P36_T0.5970.60
280_Q353_D0.5950.60
302_P347_K0.5950.60
75_G85_G0.5920.59
283_F351_V0.5900.59
45_P266_L0.5900.59
13_V31_N0.5900.59
235_P268_R0.5890.59
122_A222_V0.5880.59
210_E239_A0.5880.59
18_L103_V0.5860.58
264_P271_R0.5850.58
214_E223_R0.5840.58
191_I195_S0.5830.58
113_I117_G0.5820.58
213_F237_C0.5820.58
249_D253_D0.5820.58
20_N25_A0.5800.58
79_G85_G0.5800.58
203_M232_V0.5770.57
150_K155_D0.5770.57
102_H129_N0.5760.57
204_Y229_E0.5760.57
12_N36_T0.5750.57
6_G97_T0.5740.57
321_T358_N0.5700.56
13_V16_S0.5690.56
248_D251_E0.5680.56
349_Y355_D0.5670.56
68_M338_E0.5670.56
137_L141_E0.5670.56
125_I226_A0.5650.56
327_F331_K0.5650.56
83_G86_L0.5630.55
31_N37_I0.5610.55
327_F342_M0.5610.55
23_T135_A0.5600.55
287_V290_V0.5600.55
62_R287_V0.5590.55
79_G82_K0.5590.55
82_K89_Q0.5580.55
76_L83_G0.5580.55
66_T292_A0.5560.55
333_E339_A0.5560.55
296_P307_K0.5560.55
101_G273_G0.5550.54
16_S37_I0.5550.54
4_K43_V0.5540.54
164_V171_Q0.5530.54
125_I204_Y0.5530.54
144_I148_Q0.5520.54
214_E220_D0.5510.54
182_D188_K0.5500.54
35_C101_G0.5500.54
9_G15_K0.5490.54
47_P50_R0.5480.53
76_L85_G0.5480.53
330_Y333_E0.5470.53
23_T32_F0.5470.53
203_M273_G0.5460.53
16_S34_F0.5460.53
11_P15_K0.5450.53
55_A62_R0.5450.53
30_A33_P0.5440.53
282_Y295_I0.5440.53
141_E173_E0.5430.53
327_F333_E0.5400.52
148_Q152_K0.5400.52
60_P285_A0.5380.52
206_A235_P0.5370.52
331_K336_A0.5370.52
54_L66_T0.5360.52
160_A174_N0.5340.52
21_A32_F0.5340.52
80_A88_N0.5340.52
27_I237_C0.5330.52
59_K290_V0.5310.51
85_G88_N0.5310.51
244_I247_L0.5300.51
133_A177_M0.5300.51
145_H150_K0.5290.51
77_V80_A0.5270.51
203_M261_L0.5270.51
103_V205_I0.5260.51
206_A219_L0.5250.50
203_M208_V0.5240.50
329_T339_A0.5240.50
5_C71_V0.5240.50
212_G215_N0.5230.50
239_A244_I0.5230.50
59_K62_R0.5220.50
295_I350_I0.5220.50
60_P63_T0.5210.50
79_G83_G0.5200.50
158_A161_E0.5170.49
129_N133_A0.5170.49
5_C299_A0.5160.49
328_I331_K0.5160.49
168_C172_L0.5160.49
42_G274_Y0.5150.49
85_G90_F0.5150.49
130_T133_A0.5130.49
285_A358_N0.5120.49
240_V265_G0.5120.49
278_N296_P0.5110.49
147_V158_A0.5100.48
148_Q329_T0.5100.48
21_A44_V0.5100.48
16_S36_T0.5080.48
44_V70_F0.5080.48
53_Q331_K0.5070.48
25_A28_E0.5070.48
304_A307_K0.5060.48
345_E348_D0.5050.48
195_S199_L0.5050.48
171_Q178_L0.5040.48
157_D161_E0.5040.48
4_K35_C0.5030.48
318_R345_E0.5030.48
177_M180_A0.5020.47
177_M229_E0.5000.47
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1jalA 1 0.9587 100 0.204 Contact Map
2dbyA 1 0.9587 100 0.231 Contact Map
1ni3A 1 0.989 100 0.264 Contact Map
2ohfA 1 0.8733 100 0.366 Contact Map
1wxqA 1 0.8347 100 0.386 Contact Map
4a9aA 1 0.7851 100 0.583 Contact Map
1lnzA 1 0.5096 100 0.771 Contact Map
1udxA 1 0.6832 99.9 0.783 Contact Map
4csu9 1 0.4848 99.9 0.798 Contact Map
2ekiA 1 0.2287 99.8 0.832 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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