GREMLIN Database
DPS - DNA protection during starvation protein
UniProt: P0ABT2 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11415
Length: 167 (146)
Sequences: 2922 (1664)
Seq/√Len: 137.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
113_N116_D3.2961.00
30_V89_G2.9211.00
146_D150_A2.7301.00
46_I124_R2.5591.00
50_A120_E2.5281.00
96_Q100_S2.4411.00
39_Q103_P2.3951.00
60_I64_E2.3881.00
146_D149_T2.3821.00
47_T73_L2.2221.00
50_A107_Y2.1351.00
136_I149_T2.1011.00
92_L101_K1.9811.00
137_G145_A1.9271.00
67_D71_T1.8801.00
145_A149_T1.8751.00
143_D152_S1.7871.00
62_V66_L1.7591.00
126_A163_E1.7531.00
41_I98_I1.7511.00
45_L95_T1.7201.00
72_A158_F1.6371.00
142_D145_A1.6241.00
83_R141_D1.6101.00
50_A117_H1.5761.00
65_M68_G1.5751.00
122_A159_L1.5741.00
32_L135_A1.5731.00
126_A130_N1.5481.00
34_N92_L1.5211.00
22_S25_E1.5161.00
65_M69_F1.4971.00
119_K123_D1.4811.00
40_F80_M1.4561.00
28_A31_E1.4281.00
107_Y120_E1.4171.00
67_D70_R1.4081.00
137_G142_D1.4051.00
83_R144_T1.4041.00
129_A159_L1.4011.00
72_A76_H1.3591.00
159_L163_E1.3481.00
49_Q93_G1.3301.00
72_A154_D1.3251.00
129_A156_D1.3201.00
42_D99_N1.3171.00
79_T147_I1.2981.00
40_F73_L1.2911.00
96_Q106_S1.2901.00
76_H151_A1.2851.00
69_F125_Y1.2751.00
39_Q131_D1.2641.00
141_D144_T1.2561.00
116_D119_K1.2521.00
115_Q119_K1.2341.00
27_K31_E1.2281.00
38_I101_K1.2201.00
76_H154_D1.2171.00
130_N134_K1.1971.00
47_T69_F1.1791.00
126_A159_L1.1730.99
88_G163_E1.1300.99
42_D102_T1.1210.99
133_R156_D1.1180.99
83_R156_D1.1060.99
41_I77_L1.1050.99
118_L162_I1.1020.99
129_A152_S1.0990.99
136_I145_A1.0930.99
107_Y117_H1.0730.99
154_D157_K1.0690.99
60_I68_G1.0610.99
133_R152_S1.0550.99
34_N84_A1.0490.99
44_S74_I1.0490.99
60_I65_M1.0470.99
48_K77_L1.0360.99
135_A148_L1.0320.99
66_L117_H1.0230.99
137_G140_K1.0190.99
87_L144_T1.0180.99
23_D26_K1.0170.99
35_R131_D0.9960.98
103_P131_D0.9930.98
143_D153_R0.9920.98
103_P127_I0.9870.98
125_Y158_F0.9800.98
42_D106_S0.9710.98
142_D149_T0.9680.98
46_I106_S0.9640.98
74_I77_L0.9590.98
123_D126_A0.9530.98
36_Q135_A0.9510.98
122_A163_E0.9450.98
21_V26_K0.9350.97
136_I152_S0.9250.97
30_V84_A0.9180.97
36_Q132_V0.9120.97
35_R103_P0.9120.97
42_D95_T0.8890.97
23_D27_K0.8830.96
63_H82_E0.8590.96
125_Y155_L0.8580.96
39_Q102_T0.8550.96
58_N114_V0.8450.95
59_F82_E0.8430.95
122_A126_A0.8400.95
60_I165_N0.8380.95
71_T75_D0.8350.95
37_V80_M0.8300.95
61_A165_N0.8290.95
97_V109_L0.8180.94
75_D79_T0.8140.94
116_D120_E0.8110.94
97_V100_S0.7910.93
53_N91_A0.7900.93
64_E68_G0.7890.93
45_L93_G0.7890.93
129_A155_L0.7860.93
48_K67_D0.7720.93
99_N106_S0.7570.92
51_H82_E0.7550.92
48_K70_R0.7540.92
136_I142_D0.7510.92
36_Q131_D0.7480.91
21_V133_R0.7450.91
28_A138_E0.7450.91
154_D158_F0.7350.91
32_L35_R0.7300.90
21_V25_E0.7290.90
97_V101_K0.7280.90
24_S27_K0.7270.90
150_A153_R0.7250.90
65_M161_F0.7220.90
44_S80_M0.7200.90
118_L165_N0.7030.89
90_V111_I0.6900.88
121_L125_Y0.6900.88
51_H63_H0.6870.87
39_Q127_I0.6860.87
68_G71_T0.6860.87
132_V151_A0.6850.87
40_F76_H0.6830.87
34_N38_I0.6830.87
157_K160_W0.6810.87
83_R87_L0.6790.87
19_N23_D0.6770.87
79_T150_A0.6770.87
66_L118_L0.6770.87
61_A64_E0.6750.87
45_L98_I0.6740.86
37_V40_F0.6720.86
86_Q157_K0.6670.86
132_V155_L0.6660.86
58_N115_Q0.6660.86
54_M117_H0.6620.85
53_N93_G0.6600.85
67_D74_I0.6470.84
57_A115_Q0.6460.84
132_V148_L0.6420.84
69_F162_I0.6360.83
34_N91_A0.6330.83
84_A89_G0.6330.83
48_K161_F0.6320.83
105_K123_D0.6270.82
104_L124_R0.6220.82
58_N165_N0.6210.82
43_L47_T0.6190.81
32_L134_K0.6180.81
46_I104_L0.6170.81
95_T99_N0.6160.81
141_D156_D0.6120.81
29_T139_A0.6120.81
143_D156_D0.6090.80
31_E35_R0.6050.80
59_F63_H0.6020.80
55_R164_S0.6010.80
37_V77_L0.6010.80
92_L97_V0.5980.79
44_S77_L0.5950.79
107_Y110_D0.5870.78
146_D153_R0.5860.78
36_Q148_L0.5770.77
54_M66_L0.5760.77
26_K29_T0.5740.76
115_Q118_L0.5740.76
122_A162_I0.5740.76
66_L114_V0.5690.76
94_T97_V0.5620.75
70_R161_F0.5550.74
51_H59_F0.5490.73
55_R85_V0.5470.73
28_A139_A0.5470.73
132_V135_A0.5440.73
129_A143_D0.5430.72
152_S156_D0.5400.72
80_M151_A0.5390.72
149_T152_S0.5390.72
33_L52_W0.5370.72
120_E124_R0.5370.72
35_R101_K0.5310.71
24_S28_A0.5270.70
125_Y162_I0.5260.70
62_V118_L0.5230.70
32_L131_D0.5200.69
121_L124_R0.5150.68
70_R81_A0.5120.68
79_T153_R0.5120.68
69_F121_L0.5100.68
80_M147_I0.5090.68
107_Y112_H0.5090.68
129_A133_R0.5060.67
34_N89_G0.5030.67
36_Q39_Q0.5030.67
123_D127_I0.5020.66
114_V117_H0.5020.66
71_T74_I0.5010.66
144_T156_D0.5010.66
40_F155_L0.5000.66
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ak8A 6 0.9281 100 0.25 Contact Map
1zs3A 6 0.9581 100 0.301 Contact Map
1zujA 6 0.9401 100 0.313 Contact Map
1tjoA 6 0.994 100 0.333 Contact Map
2c2jA 6 0.8683 100 0.341 Contact Map
2c2uA 6 1 100 0.347 Contact Map
4cybA 6 0.9701 100 0.349 Contact Map
4a25A 8 0.9701 100 0.362 Contact Map
2yw6A 6 0.8683 100 0.362 Contact Map
2xgwA 6 0.9341 100 0.363 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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