DNAG - ECOLI - GREMLIN Contacts

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DNAG - DNA primase

UniProt:	P0ABS5	Sequences: MAGRIPRVFINDLLARTDIVDLIDARVKLKKQGKNFHACCPFHNEKTPSFTVNGEKQFYHCFGCGAHGNAIDFLMNYDKLEFVETVEELAAMHNLEVPFEAGSGPSQIERHQRQTLYQLMDGLNTFYQQSLQQPVATSARQYLEKRGLSHEVIARFAIGFAPPGWDNVLKRFGGNPENRQSLIDAGMLVTNDQGRSYDRFRERVMFPIRDKRGRVIGFGGRVLGNDTPKYLNSPETDIFHKGRQLYGLYEAQQDNAEPNRLLVVEGYMDVVALAQYGINYAVASLGTSTTADHIQLLFRATNNVICCYDGDRAGRDAAWRALETALPYMTDGRQLRFMFLPDGEDPDTLVRKEGKEAFEARMEQAMPLSAFLFNSLMPQVDLSTPDGRARLSTLALPLISQVPGETLRIYLRQELGNKLGILDDSQLERLMPKAAESGVSRPVPQLKRTTMRILIGLLVQNPELATLVPPLENLDENKLPGLGLFRELVNTCLSQPGLTTGQLLEHYRGTNNAATLEKLSMWDDIADKNIAEQTFTDSLNHMFDSLLELRQEELIARERTHGLSNEERLELWTLNQELAKK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10239
Length:	581 (553)
Sequences:	3921 (2926)
Seq/√Len:	124.4

ECOLI - DNAG
BACSU - DNAG

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
66_A	76_N	5.112	1.00
189_V	199_R	3.495	1.00
32_Q	37_H	3.389	1.00
210_D	214_R	3.369	1.00
216_I	244_Q	3.312	1.00
166_D	170_K	3.171	1.00
344_E	348_T	3.068	1.00
219_G	267_Y	3.042	1.00
137_T	141_Q	3.018	1.00
120_M	238_I	2.904	1.00
25_A	92_M	2.875	1.00
37_H	51_T	2.853	1.00
126_F	167_N	2.851	1.00
344_E	352_K	2.807	1.00
112_Q	184_D	2.801	1.00
45_E	63_G	2.769	1.00
40_C	64_C	2.764	1.00
59_Y	76_N	2.707	1.00
40_C	43_H	2.672	1.00
12_D	16_R	2.614	1.00
43_H	64_C	2.585	1.00
366_M	374_N	2.493	1.00
17_T	93_H	2.473	1.00
144_E	150_H	2.444	1.00
124_N	157_A	2.417	1.00
60_H	65_G	2.403	1.00
115_T	181_S	2.397	1.00
20_V	36_F	2.378	1.00
123_L	187_M	2.355	1.00
116_L	238_I	2.349	1.00
303_N	334_Q	2.343	1.00
143_L	204_V	2.343	1.00
160_F	202_E	2.324	1.00
184_D	237_D	2.322	1.00
152_V	275_Q	2.320	1.00
29_L	52_V	2.305	1.00
164_G	167_N	2.275	1.00
209_R	249_Y	2.274	1.00
260_R	280_Y	2.269	1.00
87_E	99_F	2.260	1.00
17_T	22_L	2.252	1.00
155_R	279_N	2.223	1.00
80_L	88_E	2.219	1.00
124_N	215_V	2.198	1.00
384_T	387_G	2.150	1.00
312_R	316_D	2.142	1.00
141_Q	145_K	2.138	1.00
261_L	297_L	2.137	1.00
284_S	308_Y	2.121	1.00
254_D	279_N	2.105	1.00
34_K	55_E	2.071	1.00
123_L	168_V	2.057	1.00
45_E	50_F	2.056	1.00
243_R	292_D	2.027	1.00
40_C	63_G	1.997	1.00
169_L	188_L	1.993	1.00
128_Q	157_A	1.959	1.00
370_A	414_E	1.958	1.00
255_N	261_L	1.954	1.00
27_V	38_A	1.936	1.00
43_H	63_G	1.912	1.00
206_F	246_Y	1.905	1.00
360_A	364_Q	1.903	1.00
139_A	204_V	1.890	1.00
219_G	285_L	1.874	1.00
81_E	84_E	1.869	1.00
222_V	226_D	1.864	1.00
209_R	250_E	1.850	1.00
180_Q	184_D	1.839	1.00
228_P	231_L	1.831	1.00
53_N	56_K	1.812	1.00
355_K	359_E	1.811	1.00
359_E	363_E	1.811	1.00
349_L	353_E	1.809	1.00
22_L	70_A	1.806	1.00
150_H	154_A	1.805	1.00
148_L	268_M	1.793	1.00
18_D	54_G	1.787	1.00
122_G	177_E	1.786	1.00
183_I	190_T	1.784	1.00
163_P	202_E	1.777	1.00
122_G	175_N	1.773	1.00
173_G	179_R	1.770	1.00
305_I	338_M	1.763	1.00
260_R	303_N	1.762	1.00
303_N	336_R	1.759	1.00
217_G	233_S	1.744	1.00
150_H	153_I	1.741	1.00
9_F	13_L	1.736	1.00
377_M	418_K	1.732	1.00
316_D	320_R	1.719	1.00
78_D	88_E	1.706	1.00
26_R	78_D	1.693	1.00
72_D	76_N	1.689	1.00
149_S	152_V	1.688	1.00
82_F	86_V	1.685	1.00
178_N	181_S	1.685	1.00
35_N	53_N	1.684	1.00
60_H	67_H	1.667	1.00
124_N	128_Q	1.666	1.00
482_L	485_F	1.653	1.00
138_S	202_E	1.642	1.00
59_Y	66_A	1.629	1.00
222_V	227_T	1.616	1.00
182_L	188_L	1.615	1.00
26_R	77_Y	1.601	1.00
69_N	72_D	1.596	1.00
239_F	285_L	1.559	1.00
153_I	158_I	1.548	1.00
130_S	162_P	1.546	1.00
157_A	209_R	1.539	1.00
9_F	98_P	1.534	1.00
191_N	195_R	1.532	1.00
155_R	250_E	1.531	1.00
14_L	69_N	1.529	1.00
13_L	86_V	1.528	1.00
35_N	51_T	1.526	1.00
284_S	293_H	1.524	1.00
120_M	217_G	1.517	1.00
482_L	486_R	1.508	1.00
38_A	52_V	1.502	1.00
353_E	361_R	1.501	1.00
17_T	70_A	1.491	1.00
128_Q	154_A	1.490	1.00
379_Q	394_L	1.488	1.00
140_R	150_H	1.486	1.00
235_E	240_H	1.486	1.00
117_Y	214_R	1.482	1.00
373_F	395_A	1.481	1.00
185_A	188_L	1.465	1.00
414_E	417_N	1.464	1.00
61_C	64_C	1.463	1.00
47_T	63_G	1.463	1.00
74_L	88_E	1.450	1.00
264_V	281_A	1.444	1.00
197_Y	201_R	1.444	1.00
116_L	185_A	1.443	1.00
380_V	394_L	1.441	1.00
356_E	360_A	1.433	1.00
40_C	61_C	1.433	1.00
131_L	143_L	1.431	1.00
53_N	58_F	1.428	1.00
233_S	236_T	1.427	1.00
310_G	344_E	1.426	1.00
149_S	275_Q	1.418	1.00
340_L	361_R	1.417	1.00
14_L	71_I	1.413	1.00
10_I	86_V	1.411	1.00
336_R	365_A	1.402	1.00
294_I	324_T	1.391	1.00
550_R	553_E	1.389	1.00
47_T	50_F	1.388	1.00
50_F	63_G	1.385	1.00
140_R	153_I	1.376	1.00
396_L	430_L	1.371	1.00
294_I	325_A	1.366	1.00
140_R	144_E	1.359	1.00
121_D	157_A	1.359	1.00
117_Y	238_I	1.355	1.00
165_W	201_R	1.354	1.00
7_R	11_N	1.353	1.00
169_L	179_R	1.350	1.00
11_N	15_A	1.349	1.00
165_W	197_Y	1.344	1.00
136_A	140_R	1.342	1.00
412_R	426_Q	1.335	1.00
120_M	185_A	1.329	1.00
14_L	70_A	1.318	1.00
43_H	61_C	1.307	1.00
18_D	21_D	1.299	1.00
199_R	234_P	1.293	1.00
115_T	118_Q	1.281	1.00
338_M	361_R	1.274	1.00
242_G	292_D	1.273	1.00
264_V	273_L	1.271	1.00
533_Q	537_D	1.268	1.00
505_E	508_R	1.262	1.00
129_Q	133_Q	1.258	1.00
13_L	95_L	1.256	1.00
247_G	274_A	1.254	1.00
151_E	154_A	1.253	1.00
144_E	153_I	1.251	1.00
9_F	95_L	1.249	1.00
307_C	358_F	1.247	1.00
126_F	130_S	1.239	0.99
132_Q	150_H	1.237	0.99
183_I	196_S	1.228	0.99
413_Q	423_D	1.225	0.99
132_Q	140_R	1.224	0.99
126_F	162_P	1.221	0.99
259_N	302_N	1.218	0.99
171_R	175_N	1.216	0.99
360_A	363_E	1.211	0.99
350_V	358_F	1.211	0.99
185_A	236_T	1.211	0.99
354_G	357_A	1.209	0.99
240_H	243_R	1.207	0.99
278_I	359_E	1.205	0.99
169_L	173_G	1.205	0.99
527_D	530_I	1.198	0.99
17_T	89_L	1.197	0.99
188_L	196_S	1.187	0.99
258_P	359_E	1.186	0.99
481_G	485_F	1.182	0.99
344_E	353_E	1.176	0.99
46_K	63_G	1.174	0.99
561_H	566_E	1.174	0.99
165_W	195_R	1.173	0.99
503_L	507_Y	1.166	0.99
551_Q	555_I	1.164	0.99
121_D	125_T	1.160	0.99
161_A	205_M	1.159	0.99
553_E	557_R	1.153	0.99
19_I	22_L	1.152	0.99
35_N	58_F	1.151	0.99
267_Y	285_L	1.150	0.99
170_K	174_G	1.148	0.99
60_H	66_A	1.148	0.99
556_A	560_T	1.147	0.99
83_V	87_E	1.147	0.99
128_Q	132_Q	1.140	0.99
183_I	188_L	1.139	0.99
80_L	85_T	1.136	0.99
9_F	97_V	1.136	0.99
17_T	92_M	1.135	0.99
242_G	293_H	1.132	0.99
158_I	271_V	1.131	0.99
177_E	182_L	1.130	0.99
16_R	95_L	1.130	0.99
134_P	137_T	1.129	0.99
304_V	325_A	1.128	0.99
39_C	45_E	1.127	0.99
191_N	197_Y	1.126	0.99
141_Q	144_E	1.126	0.99
20_V	54_G	1.125	0.99
114_Q	118_Q	1.122	0.99
121_D	214_R	1.122	0.99
390_R	394_L	1.118	0.99
247_G	250_E	1.113	0.99
29_L	38_A	1.110	0.99
307_C	340_L	1.102	0.99
319_W	372_L	1.100	0.99
6_P	98_P	1.099	0.99
87_E	91_A	1.096	0.99
199_R	231_L	1.094	0.99
156_F	274_A	1.091	0.99
481_G	484_L	1.090	0.99
143_L	153_I	1.088	0.99
120_M	233_S	1.088	0.99
563_L	566_E	1.086	0.99
208_I	219_G	1.082	0.99
148_L	153_I	1.080	0.99
143_L	158_I	1.079	0.99
322_L	368_L	1.078	0.99
548_E	552_E	1.078	0.99
222_V	228_P	1.077	0.99
562_G	565_N	1.076	0.99
120_M	127_Y	1.065	0.98
172_F	182_L	1.064	0.98
119_L	181_S	1.064	0.98
298_F	333_R	1.063	0.98
12_D	15_A	1.061	0.98
89_L	92_M	1.058	0.98
302_N	333_R	1.056	0.98
347_D	351_R	1.055	0.98
247_G	270_V	1.055	0.98
60_H	63_G	1.051	0.98
122_G	171_R	1.046	0.98
17_T	21_D	1.045	0.98
190_T	196_S	1.045	0.98
260_R	363_E	1.044	0.98
555_I	559_R	1.041	0.98
46_K	50_F	1.041	0.98
484_L	488_L	1.035	0.98
325_A	335_L	1.034	0.98
552_E	555_I	1.031	0.98
59_Y	67_H	1.030	0.98
18_D	57_Q	1.030	0.98
74_L	80_L	1.026	0.98
23_I	27_V	1.026	0.98
119_L	177_E	1.023	0.98
356_E	359_E	1.022	0.98
414_E	418_K	1.021	0.98
273_L	350_V	1.019	0.98
485_F	488_L	1.012	0.98
26_R	73_F	1.010	0.98
40_C	66_A	1.010	0.98
276_Y	355_K	1.008	0.98
380_V	387_G	1.007	0.98
122_G	125_T	1.006	0.98
541_H	544_D	1.003	0.98
205_M	220_G	1.000	0.98
32_Q	51_T	0.999	0.98
244_Q	285_L	0.999	0.98
57_Q	70_A	0.998	0.98
408_R	412_R	0.998	0.98
278_I	350_V	0.997	0.98
58_F	67_H	0.994	0.98
558_E	563_L	0.991	0.98
189_V	197_Y	0.987	0.97
200_F	205_M	0.985	0.97
552_E	556_A	0.983	0.97
88_E	92_M	0.983	0.97
136_A	139_A	0.979	0.97
222_V	225_N	0.979	0.97
561_H	565_N	0.976	0.97
485_F	489_V	0.975	0.97
486_R	490_N	0.970	0.97
537_D	541_H	0.962	0.97
148_L	206_F	0.960	0.97
273_L	358_F	0.959	0.97
137_T	140_R	0.957	0.97
357_A	360_A	0.957	0.97
209_R	215_V	0.957	0.97
172_F	177_E	0.951	0.97
123_L	127_Y	0.949	0.97
308_Y	321_A	0.948	0.97
24_D	28_K	0.947	0.97
5_I	83_V	0.940	0.97
467_L	532_E	0.938	0.97
179_R	196_S	0.935	0.96
17_T	74_L	0.935	0.96
181_S	184_D	0.935	0.96
71_I	86_V	0.930	0.96
284_S	306_C	0.926	0.96
422_L	425_S	0.925	0.96
254_D	258_P	0.923	0.96
38_A	50_F	0.920	0.96
160_F	223_L	0.918	0.96
36_F	54_G	0.918	0.96
132_Q	154_A	0.918	0.96
39_C	47_T	0.916	0.96
282_V	297_L	0.914	0.96
499_T	502_Q	0.913	0.96
51_T	58_F	0.912	0.96
353_E	357_A	0.910	0.96
270_V	281_A	0.910	0.96
510_T	513_A	0.908	0.96
289_T	321_A	0.905	0.96
482_L	488_L	0.903	0.96
377_M	391_L	0.902	0.96
29_L	33_G	0.899	0.96
288_S	320_R	0.899	0.96
71_I	89_L	0.898	0.96
180_Q	183_I	0.897	0.96
202_E	224_G	0.888	0.95
13_L	71_I	0.885	0.95
35_N	56_K	0.885	0.95
39_C	50_F	0.881	0.95
189_V	231_L	0.881	0.95
289_T	294_I	0.881	0.95
272_A	276_Y	0.881	0.95
5_I	9_F	0.881	0.95
248_L	300_A	0.881	0.95
179_R	183_I	0.879	0.95
44_N	63_G	0.878	0.95
262_L	278_I	0.877	0.95
242_G	290_T	0.876	0.95
262_L	273_L	0.873	0.95
490_N	494_S	0.873	0.95
280_Y	359_E	0.867	0.95
260_R	305_I	0.867	0.95
147_G	351_R	0.865	0.95
472_E	476_E	0.865	0.95
416_G	421_I	0.864	0.95
246_Y	267_Y	0.863	0.94
79_K	256_A	0.861	0.94
231_L	239_F	0.857	0.94
39_C	63_G	0.855	0.94
381_D	387_G	0.854	0.94
179_R	190_T	0.847	0.94
119_L	185_A	0.847	0.94
186_G	234_P	0.847	0.94
349_L	358_F	0.847	0.94
26_R	88_E	0.846	0.94
88_E	91_A	0.846	0.94
412_R	430_L	0.845	0.94
130_S	133_Q	0.844	0.94
138_S	141_Q	0.843	0.94
255_N	301_T	0.842	0.94
39_C	46_K	0.842	0.94
132_Q	153_I	0.838	0.94
12_D	95_L	0.837	0.94
84_E	87_E	0.837	0.94
165_W	191_N	0.837	0.94
11_N	14_L	0.836	0.94
412_R	427_L	0.836	0.94
263_V	306_C	0.835	0.93
482_L	489_V	0.834	0.93
19_I	59_Y	0.833	0.93
297_L	333_R	0.833	0.93
483_G	486_R	0.832	0.93
74_L	77_Y	0.832	0.93
127_Y	167_N	0.825	0.93
289_T	306_C	0.824	0.93
162_P	167_N	0.824	0.93
220_G	267_Y	0.821	0.93
416_G	426_Q	0.820	0.93
153_I	204_V	0.818	0.93
395_A	415_L	0.814	0.93
530_I	533_Q	0.814	0.93
139_A	143_L	0.812	0.93
423_D	427_L	0.811	0.92
514_A	518_K	0.811	0.92
151_E	155_R	0.810	0.92
396_L	412_R	0.807	0.92
224_G	228_P	0.807	0.92
217_G	244_Q	0.806	0.92
239_F	293_H	0.806	0.92
556_A	559_R	0.805	0.92
284_S	321_A	0.803	0.92
127_Y	168_V	0.802	0.92
338_M	362_M	0.802	0.92
485_F	492_C	0.802	0.92
274_A	279_N	0.801	0.92
310_G	341_P	0.799	0.92
374_N	418_K	0.798	0.92
43_H	66_A	0.798	0.92
124_N	205_M	0.798	0.92
119_L	123_L	0.797	0.92
191_N	194_G	0.797	0.92
558_E	561_H	0.796	0.92
13_L	17_T	0.794	0.92
190_T	194_G	0.793	0.92
315_R	339_F	0.792	0.92
306_C	325_A	0.791	0.92
219_G	231_L	0.791	0.92
118_Q	122_G	0.789	0.91
213_G	249_Y	0.789	0.91
550_R	554_L	0.789	0.91
310_G	343_G	0.789	0.91
166_D	169_L	0.784	0.91
240_H	292_D	0.782	0.91
262_L	362_M	0.782	0.91
508_R	513_A	0.781	0.91
126_F	171_R	0.778	0.91
557_R	561_H	0.778	0.91
534_T	538_S	0.777	0.91
155_R	274_A	0.776	0.91
548_E	551_Q	0.775	0.91
479_L	486_R	0.774	0.91
413_Q	417_N	0.774	0.91
319_W	375_S	0.773	0.91
8_V	12_D	0.773	0.91
549_L	552_E	0.773	0.91
381_D	384_T	0.771	0.90
318_A	339_F	0.770	0.90
487_E	490_N	0.767	0.90
260_R	301_T	0.767	0.90
509_G	513_A	0.767	0.90
535_F	539_L	0.766	0.90
562_G	566_E	0.765	0.90
481_G	488_L	0.764	0.90
291_A	330_T	0.764	0.90
386_D	390_R	0.764	0.90
348_T	351_R	0.763	0.90
5_I	10_I	0.760	0.90
375_S	378_P	0.760	0.90
454_L	535_F	0.758	0.90
421_I	426_Q	0.758	0.90
90_A	93_H	0.756	0.90
37_H	58_F	0.753	0.89
28_K	39_C	0.753	0.89
479_L	482_L	0.752	0.89
72_D	75_M	0.751	0.89
366_M	370_A	0.751	0.89
9_F	12_D	0.751	0.89
429_R	432_P	0.750	0.89
206_F	268_M	0.749	0.89
182_L	185_A	0.748	0.89
385_P	410_Y	0.744	0.89
549_L	553_E	0.742	0.89
260_R	359_E	0.742	0.89
259_N	303_N	0.740	0.89
217_G	240_H	0.739	0.89
342_D	353_E	0.737	0.88
289_T	308_Y	0.737	0.88
23_I	77_Y	0.737	0.88
477_N	480_P	0.736	0.88
270_V	310_G	0.734	0.88
298_F	302_N	0.734	0.88
408_R	434_A	0.733	0.88
433_K	436_E	0.733	0.88
340_L	344_E	0.731	0.88
376_L	394_L	0.729	0.88
156_F	246_Y	0.729	0.88
127_Y	161_A	0.729	0.88
133_Q	136_A	0.727	0.88
409_I	427_L	0.726	0.88
208_I	244_Q	0.725	0.88
431_M	434_A	0.723	0.87
560_T	563_L	0.722	0.87
76_N	79_K	0.721	0.87
559_R	563_L	0.721	0.87
168_V	172_F	0.720	0.87
516_L	520_S	0.719	0.87
262_L	307_C	0.719	0.87
23_I	52_V	0.718	0.87
412_R	416_G	0.717	0.87
37_H	48_P	0.715	0.87
410_Y	414_E	0.703	0.86
274_A	281_A	0.703	0.86
90_A	97_V	0.703	0.86
284_S	288_S	0.700	0.86
293_H	308_Y	0.700	0.86
372_L	398_L	0.699	0.86
504_L	507_Y	0.697	0.85
5_I	97_V	0.697	0.85
291_A	324_T	0.696	0.85
125_T	157_A	0.696	0.85
166_D	195_R	0.696	0.85
409_I	422_L	0.695	0.85
161_A	202_E	0.695	0.85
168_V	187_M	0.694	0.85
296_L	300_A	0.691	0.85
402_V	411_L	0.691	0.85
10_I	13_L	0.691	0.85
24_D	316_D	0.691	0.85
165_W	193_Q	0.690	0.85
376_L	395_A	0.690	0.85
485_F	490_N	0.688	0.85
323_E	401_Q	0.686	0.85
272_A	275_Q	0.685	0.84
262_L	305_I	0.684	0.84
367_P	370_A	0.684	0.84
204_V	223_L	0.683	0.84
534_T	537_D	0.683	0.84
507_Y	512_N	0.682	0.84
554_L	557_R	0.681	0.84
264_V	270_V	0.681	0.84
499_T	503_L	0.678	0.84
122_G	172_F	0.677	0.84
537_D	542_M	0.677	0.84
533_Q	536_T	0.676	0.84
31_K	36_F	0.675	0.84
186_G	199_R	0.675	0.84
108_I	112_Q	0.675	0.84
489_V	492_C	0.675	0.84
124_N	218_F	0.674	0.83
136_A	204_V	0.674	0.83
59_Y	72_D	0.673	0.83
20_V	24_D	0.673	0.83
276_Y	350_V	0.673	0.83
353_E	360_A	0.672	0.83
409_I	425_S	0.672	0.83
557_R	560_T	0.672	0.83
74_L	78_D	0.671	0.83
476_E	479_L	0.671	0.83
558_E	562_G	0.669	0.83
288_S	306_C	0.668	0.83
390_R	393_T	0.667	0.83
91_A	96_E	0.667	0.83
500_T	503_L	0.667	0.83
294_I	333_R	0.666	0.83
23_I	38_A	0.664	0.83
336_R	384_T	0.663	0.82
288_S	318_A	0.662	0.82
37_H	47_T	0.662	0.82
127_Y	198_D	0.662	0.82
28_K	38_A	0.661	0.82
293_H	296_L	0.660	0.82
391_L	394_L	0.657	0.82
208_I	217_G	0.657	0.82
451_M	478_K	0.656	0.82
18_D	36_F	0.654	0.82
258_P	279_N	0.654	0.82
538_S	542_M	0.654	0.82
388_R	410_Y	0.653	0.82
5_I	86_V	0.653	0.82
208_I	267_Y	0.652	0.81
554_L	558_E	0.652	0.81
376_L	391_L	0.652	0.81
261_L	301_T	0.651	0.81
391_L	419_L	0.651	0.81
190_T	195_R	0.650	0.81
75_M	83_V	0.649	0.81
424_D	427_L	0.648	0.81
179_R	188_L	0.647	0.81
530_I	538_S	0.646	0.81
561_H	564_S	0.645	0.81
208_I	285_L	0.644	0.81
51_T	60_H	0.644	0.81
531_A	534_T	0.644	0.81
315_R	375_S	0.643	0.81
246_Y	270_V	0.642	0.80
273_L	281_A	0.642	0.80
140_R	204_V	0.642	0.80
259_N	301_T	0.639	0.80
45_E	49_S	0.638	0.80
559_R	562_G	0.637	0.80
206_F	271_V	0.636	0.80
527_D	531_A	0.636	0.80
69_N	75_M	0.635	0.80
515_T	518_K	0.635	0.80
483_G	488_L	0.634	0.80
560_T	564_S	0.632	0.79
487_E	491_T	0.631	0.79
323_E	372_L	0.631	0.79
119_L	187_M	0.630	0.79
349_L	361_R	0.630	0.79
5_I	17_T	0.630	0.79
310_G	346_P	0.629	0.79
253_Q	257_E	0.629	0.79
51_T	69_N	0.629	0.79
30_K	33_G	0.628	0.79
38_A	77_Y	0.628	0.79
459_V	519_L	0.628	0.79
107_Q	111_H	0.626	0.79
553_E	556_A	0.626	0.79
364_Q	463_E	0.626	0.79
410_Y	413_Q	0.626	0.79
28_K	57_Q	0.625	0.79
165_W	189_V	0.624	0.79
382_L	387_G	0.624	0.79
298_F	331_D	0.622	0.78
474_L	477_N	0.622	0.78
264_V	278_I	0.622	0.78
341_P	344_E	0.621	0.78
21_D	39_C	0.621	0.78
219_G	247_G	0.621	0.78
514_A	517_E	0.620	0.78
123_L	198_D	0.619	0.78
114_Q	214_R	0.618	0.78
472_E	477_N	0.617	0.78
296_L	299_R	0.615	0.78
169_L	196_S	0.615	0.78
396_L	433_K	0.613	0.77
247_G	285_L	0.613	0.77
55_E	256_A	0.611	0.77
22_L	89_L	0.609	0.77
498_L	503_L	0.609	0.77
25_A	38_A	0.609	0.77
13_L	70_A	0.608	0.77
258_P	280_Y	0.606	0.77
260_R	365_A	0.606	0.77
454_L	538_S	0.606	0.77
339_F	374_N	0.606	0.77
7_R	14_L	0.604	0.76
326_L	401_Q	0.604	0.76
224_G	227_T	0.602	0.76
532_E	536_T	0.601	0.76
402_V	407_L	0.601	0.76
63_G	66_A	0.600	0.76
495_Q	502_Q	0.600	0.76
469_P	472_E	0.599	0.76
405_E	408_R	0.599	0.76
560_T	565_N	0.598	0.76
164_G	202_E	0.598	0.76
306_C	337_F	0.597	0.75
119_L	172_F	0.597	0.75
60_H	74_L	0.596	0.75
539_L	542_M	0.596	0.75
130_S	167_N	0.596	0.75
544_D	548_E	0.595	0.75
216_I	238_I	0.594	0.75
6_P	9_F	0.593	0.75
485_F	493_L	0.593	0.75
405_E	409_I	0.592	0.75
254_D	257_E	0.591	0.75
211_K	252_Q	0.590	0.75
407_L	410_Y	0.590	0.75
429_R	433_K	0.589	0.74
310_G	361_R	0.588	0.74
187_M	205_M	0.588	0.74
531_A	537_D	0.587	0.74
200_F	231_L	0.586	0.74
75_M	80_L	0.586	0.74
110_R	114_Q	0.585	0.74
45_E	60_H	0.583	0.74
272_A	281_A	0.583	0.74
217_G	247_G	0.582	0.74
350_V	354_G	0.582	0.74
385_P	389_A	0.582	0.74
154_A	157_A	0.582	0.74
244_Q	248_L	0.581	0.73
208_I	228_P	0.579	0.73
278_I	362_M	0.579	0.73
428_E	431_M	0.578	0.73
307_C	338_M	0.577	0.73
426_Q	430_L	0.577	0.73
245_L	282_V	0.576	0.73
400_S	408_R	0.576	0.73
394_L	397_P	0.573	0.72
320_R	323_E	0.573	0.72
482_L	487_E	0.573	0.72
272_A	351_R	0.572	0.72
325_A	337_F	0.572	0.72
39_C	48_P	0.571	0.72
541_H	545_S	0.570	0.72
412_R	423_D	0.570	0.72
499_T	504_L	0.570	0.72
108_I	111_H	0.570	0.72
181_S	185_A	0.569	0.72
247_G	264_V	0.567	0.72
168_V	198_D	0.566	0.72
377_M	382_L	0.565	0.71
22_L	73_F	0.564	0.71
81_E	88_E	0.562	0.71
483_G	487_E	0.561	0.71
200_F	233_S	0.561	0.71
545_S	548_E	0.560	0.71
113_R	237_D	0.559	0.71
160_F	204_V	0.559	0.71
291_A	295_Q	0.559	0.71
502_Q	505_E	0.558	0.70
116_L	120_M	0.558	0.70
205_M	218_F	0.558	0.70
198_D	201_R	0.556	0.70
103_S	108_I	0.556	0.70
308_Y	369_S	0.556	0.70
165_W	198_D	0.556	0.70
191_N	196_S	0.556	0.70
51_T	59_Y	0.555	0.70
428_E	441_R	0.555	0.70
179_R	182_L	0.554	0.70
177_E	185_A	0.553	0.70
272_A	350_V	0.553	0.70
380_V	391_L	0.553	0.70
310_G	339_F	0.551	0.70
270_V	274_A	0.550	0.69
81_E	456_G	0.550	0.69
112_Q	237_D	0.549	0.69
23_I	59_Y	0.548	0.69
225_N	228_P	0.547	0.69
75_M	82_F	0.546	0.69
481_G	487_E	0.546	0.69
145_K	225_N	0.545	0.69
458_L	468_V	0.545	0.69
78_D	252_Q	0.545	0.69
4_R	7_R	0.545	0.69
450_T	454_L	0.545	0.69
424_D	428_E	0.544	0.69
268_M	347_D	0.542	0.68
547_L	554_L	0.542	0.68
206_F	270_V	0.541	0.68
5_I	100_E	0.541	0.68
211_K	300_A	0.541	0.68
491_T	503_L	0.541	0.68
173_G	176_P	0.540	0.68
496_P	499_T	0.540	0.68
469_P	493_L	0.540	0.68
239_F	244_Q	0.540	0.68
507_Y	516_L	0.539	0.68
448_R	533_Q	0.539	0.68
551_Q	557_R	0.539	0.68
540_N	546_L	0.539	0.68
165_W	192_D	0.538	0.68
451_M	481_G	0.538	0.68
453_I	534_T	0.538	0.68
334_Q	390_R	0.537	0.68
425_S	429_R	0.537	0.68
247_G	267_Y	0.536	0.67
555_I	558_E	0.536	0.67
156_F	271_V	0.535	0.67
318_A	322_L	0.535	0.67
125_T	175_N	0.535	0.67
158_I	206_F	0.535	0.67
455_I	485_F	0.533	0.67
396_L	426_Q	0.533	0.67
13_L	90_A	0.533	0.67
305_I	362_M	0.533	0.67
209_R	310_G	0.533	0.67
71_I	95_L	0.532	0.67
554_L	561_H	0.531	0.67
119_L	122_G	0.531	0.67
152_V	155_R	0.531	0.67
400_S	433_K	0.530	0.67
287_T	310_G	0.530	0.67
294_I	372_L	0.529	0.66
222_V	268_M	0.528	0.66
370_A	374_N	0.528	0.66
273_L	307_C	0.528	0.66
417_N	423_D	0.527	0.66
7_R	10_I	0.527	0.66
258_P	301_T	0.527	0.66
495_Q	498_L	0.526	0.66
19_I	35_N	0.525	0.66
496_P	500_T	0.525	0.66
51_T	56_K	0.525	0.66
505_E	513_A	0.525	0.66
39_C	44_N	0.524	0.66
148_L	272_A	0.522	0.65
20_V	53_N	0.522	0.65
392_S	406_T	0.521	0.65
531_A	538_S	0.521	0.65
488_L	492_C	0.520	0.65
71_I	77_Y	0.519	0.65
19_I	23_I	0.518	0.65
188_L	198_D	0.518	0.65
161_A	201_R	0.518	0.65
125_T	128_Q	0.517	0.65
65_G	316_D	0.517	0.65
385_P	407_L	0.517	0.65
20_V	57_Q	0.516	0.65
23_I	70_A	0.516	0.65
374_N	378_P	0.515	0.64
255_N	259_N	0.515	0.64
250_E	274_A	0.514	0.64
111_H	184_D	0.514	0.64
120_M	188_L	0.513	0.64
243_R	318_A	0.512	0.64
231_L	285_L	0.511	0.64
409_I	423_D	0.511	0.64
404_G	429_R	0.511	0.64
500_T	504_L	0.511	0.64
113_R	210_D	0.511	0.64
528_K	531_A	0.510	0.64
8_V	11_N	0.509	0.63
27_V	77_Y	0.509	0.63
24_D	38_A	0.508	0.63
342_D	352_K	0.507	0.63
271_V	350_V	0.507	0.63
255_N	258_P	0.507	0.63
201_R	205_M	0.507	0.63
297_L	304_V	0.507	0.63
326_L	337_F	0.506	0.63
217_G	239_F	0.506	0.63
529_N	532_E	0.506	0.63
118_Q	121_D	0.506	0.63
503_L	506_H	0.505	0.63
369_S	386_D	0.505	0.63
51_T	67_H	0.505	0.63
392_S	426_Q	0.505	0.63
371_F	414_E	0.504	0.63
404_G	407_L	0.504	0.63
476_E	480_P	0.501	0.62
376_L	398_L	0.501	0.62
270_V	287_T	0.500	0.62
27_V	52_V	0.500	0.62
479_L	484_L	0.500	0.62

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2au3A	1	0.6919	100	0.344	Contact Map
1dd9A	1	0.5318	100	0.506	Contact Map
4edgA	1	0.5473	100	0.527	Contact Map
1nuiA	1	0.4045	100	0.746	Contact Map
1q57A	3	0.6403	100	0.781	Contact Map
1d0qA	2	0.1756	100	0.79	Contact Map
1t6t1	2	0.1756	100	0.843	Contact Map
2fcjA	2	0.1962	98.9	0.934	Contact Map
2r6aC	1	0.2358	98.5	0.941	Contact Map
1t3wA	4	0.2324	98.2	0.946	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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