DEOD - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

DEOD - Purine nucleoside phosphorylase DeoD-type

UniProt:	P0ABP8	Sequences: MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLRDVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGIDARVGNLFSADLFYSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAERQTTFNDMIKIALESVLLGDKE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10222
Length:	239 (218)
Sequences:	6899 (4915)
Seq/√Len:	332.9

ECOLI - DEOD UDP MTNN
BACSU - DEOD MTNN
HALSA - Q9HP14 Q9HR25
SULSO - PNPH

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
36_D	52_T	3.548	1.00
92_C	203_V	3.038	1.00
190_A	197_A	2.940	1.00
15_D	84_K	2.835	1.00
155_F	176_I	2.698	1.00
78_I	195_A	2.678	1.00
108_M	151_V	2.571	1.00
183_A	199_T	2.557	1.00
139_V	151_V	2.475	1.00
52_T	57_K	2.434	1.00
131_D	196_K	2.426	1.00
109_G	153_N	2.417	1.00
169_D	173_K	2.405	1.00
85_K	196_K	2.335	1.00
16_V	85_K	2.278	1.00
67_I	158_D	2.186	1.00
105_V	178_G	2.014	1.00
27_K	31_E	2.006	1.00
107_G	154_L	1.999	1.00
42_N	47_L	1.912	1.00
139_V	143_K	1.910	1.00
96_L	177_L	1.867	1.00
166_E	169_D	1.853	1.00
100_K	103_D	1.833	1.00
17_V	77_L	1.820	1.00
214_T	217_E	1.803	1.00
76_E	79_T	1.783	1.00
92_C	178_G	1.763	1.00
75_K	193_F	1.721	1.00
109_G	129_I	1.714	1.00
38_R	57_K	1.703	1.00
180_E	183_A	1.700	1.00
23_P	62_G	1.678	1.00
223_N	227_K	1.646	1.00
67_I	185_G	1.631	1.00
18_L	29_I	1.623	1.00
152_G	177_L	1.617	1.00
28_Y	223_N	1.556	1.00
154_L	178_G	1.553	1.00
99_V	150_R	1.545	1.00
75_K	79_T	1.515	1.00
136_R	140_D	1.508	1.00
20_P	26_A	1.498	1.00
105_V	177_L	1.486	1.00
84_K	195_A	1.438	1.00
30_A	49_F	1.431	1.00
106_I	149_A	1.419	1.00
15_D	57_K	1.407	1.00
135_V	151_V	1.403	1.00
61_M	73_Y	1.382	1.00
67_I	156_S	1.375	1.00
112_T	188_G	1.371	1.00
74_T	189_V	1.361	1.00
178_G	203_V	1.346	1.00
134_M	198_L	1.335	1.00
74_T	86_I	1.329	1.00
79_T	193_F	1.322	1.00
39_E	50_T	1.320	1.00
132_F	136_R	1.316	1.00
50_T	59_S	1.314	1.00
70_C	186_I	1.299	1.00
167_M	171_M	1.279	1.00
154_L	201_C	1.274	1.00
16_V	56_R	1.266	1.00
19_M	63_H	1.248	1.00
21_G	88_R	1.244	1.00
142_A	149_A	1.229	1.00
34_L	51_G	1.217	1.00
220_T	224_D	1.217	1.00
215_A	218_R	1.212	1.00
132_F	135_V	1.210	1.00
53_Y	230_L	1.210	1.00
168_F	172_E	1.208	1.00
19_M	86_I	1.207	1.00
26_A	49_F	1.202	1.00
103_D	150_R	1.202	1.00
138_A	198_L	1.201	1.00
130_A	135_V	1.189	1.00
26_A	60_V	1.185	1.00
135_V	138_A	1.184	1.00
78_I	86_I	1.174	1.00
206_H	209_T	1.166	1.00
98_H	150_R	1.165	1.00
109_G	127_A	1.160	1.00
115_K	119_I	1.158	1.00
141_A	144_A	1.157	1.00
163_P	166_E	1.154	1.00
126_F	129_I	1.154	1.00
106_I	135_V	1.148	1.00
40_V	47_L	1.138	1.00
135_V	139_V	1.137	1.00
94_A	99_V	1.136	1.00
41_N	81_F	1.135	1.00
46_M	62_G	1.129	1.00
115_K	118_R	1.129	1.00
213_T	216_A	1.128	1.00
35_E	52_T	1.117	1.00
150_R	177_L	1.112	1.00
39_E	42_N	1.111	1.00
94_A	206_H	1.110	1.00
68_P	158_D	1.103	1.00
138_A	232_S	1.101	1.00
94_A	203_V	1.092	1.00
170_V	174_Y	1.081	1.00
110_A	183_A	1.080	1.00
29_I	60_V	1.068	1.00
169_D	172_E	1.067	1.00
187_Y	197_A	1.062	1.00
137_N	141_A	1.057	1.00
88_R	186_I	1.056	1.00
48_G	61_M	1.055	1.00
110_A	187_Y	1.050	1.00
34_L	37_A	1.047	1.00
95_V	179_V	1.045	1.00
86_I	190_A	1.039	1.00
67_I	114_S	1.034	1.00
141_A	145_L	1.032	1.00
135_V	198_L	1.031	1.00
112_T	184_A	1.025	1.00
134_M	138_A	1.008	1.00
48_G	59_S	1.007	1.00
138_A	141_A	1.003	1.00
133_D	196_K	1.001	1.00
113_D	157_A	0.995	1.00
227_K	231_E	0.994	1.00
78_I	83_V	0.992	1.00
21_G	25_R	0.990	1.00
50_T	57_K	0.987	1.00
78_I	193_F	0.982	1.00
145_L	231_E	0.976	1.00
167_M	170_V	0.970	1.00
17_V	83_V	0.969	1.00
106_I	139_V	0.966	1.00
140_D	143_K	0.957	1.00
121_F	124_H	0.950	1.00
219_Q	223_N	0.939	1.00
52_T	55_G	0.939	1.00
170_V	173_K	0.934	1.00
156_S	183_A	0.930	1.00
120_R	124_H	0.930	1.00
23_P	27_K	0.927	1.00
115_K	120_R	0.924	1.00
28_Y	31_E	0.915	1.00
41_N	50_T	0.913	1.00
168_F	171_M	0.912	1.00
222_F	226_I	0.908	1.00
105_V	203_V	0.904	1.00
136_R	139_V	0.897	1.00
213_T	217_E	0.897	1.00
100_K	209_T	0.891	1.00
71_S	189_V	0.890	1.00
110_A	199_T	0.883	1.00
224_D	227_K	0.877	1.00
91_S	205_D	0.875	1.00
33_F	230_L	0.867	1.00
155_F	170_V	0.864	1.00
107_G	187_Y	0.862	1.00
140_D	144_A	0.858	1.00
145_L	227_K	0.857	1.00
54_K	231_E	0.856	1.00
28_Y	226_I	0.855	1.00
198_L	232_S	0.855	1.00
123_D	173_K	0.853	1.00
70_C	185_G	0.851	1.00
92_C	201_C	0.850	1.00
72_I	189_V	0.847	1.00
137_N	232_S	0.845	1.00
93_G	207_I	0.842	1.00
133_D	137_N	0.836	1.00
40_V	61_M	0.835	1.00
100_K	211_E	0.829	1.00
185_G	189_V	0.828	1.00
160_F	181_M	0.825	1.00
134_M	137_N	0.824	1.00
121_F	125_D	0.820	1.00
100_K	206_H	0.819	1.00
202_T	218_R	0.816	1.00
108_M	153_N	0.811	1.00
179_V	207_I	0.808	1.00
77_L	83_V	0.808	1.00
74_T	186_I	0.799	1.00
118_R	125_D	0.791	1.00
139_V	149_A	0.790	1.00
26_A	62_G	0.789	1.00
133_D	136_R	0.787	1.00
116_V	121_F	0.781	1.00
85_K	134_M	0.780	1.00
116_V	119_I	0.779	1.00
106_I	198_L	0.771	1.00
111_C	155_F	0.767	1.00
72_I	76_E	0.766	1.00
95_V	171_M	0.766	1.00
164_D	168_F	0.765	1.00
61_M	77_L	0.764	1.00
122_K	125_D	0.761	1.00
95_V	176_I	0.761	1.00
48_G	81_F	0.759	1.00
117_N	120_R	0.757	1.00
72_I	75_K	0.756	1.00
34_L	60_V	0.754	1.00
46_M	73_Y	0.750	0.99
102_R	221_T	0.749	0.99
20_P	89_V	0.747	0.99
107_G	201_C	0.743	0.99
131_D	138_A	0.742	0.99
147_I	227_K	0.736	0.99
113_D	159_L	0.735	0.99
17_V	59_S	0.734	0.99
43_V	80_D	0.731	0.99
137_N	140_D	0.726	0.99
106_I	151_V	0.724	0.99
30_A	37_A	0.724	0.99
95_V	207_I	0.722	0.99
30_A	60_V	0.715	0.99
104_V	202_T	0.714	0.99
126_F	132_F	0.707	0.99
23_P	30_A	0.706	0.99
107_G	178_G	0.704	0.99
102_R	213_T	0.700	0.99
127_A	153_N	0.699	0.99
214_T	218_R	0.695	0.99
59_S	81_F	0.692	0.99
113_D	155_F	0.692	0.99
70_C	74_T	0.691	0.99
27_K	30_A	0.689	0.99
92_C	105_V	0.687	0.99
141_A	232_S	0.686	0.99
166_E	170_V	0.682	0.99
220_T	223_N	0.682	0.99
106_I	225_M	0.678	0.99
15_D	56_R	0.675	0.99
120_R	123_D	0.675	0.99
127_A	130_A	0.675	0.99
132_F	139_V	0.673	0.99
187_Y	199_T	0.670	0.99
165_G	168_F	0.665	0.99
142_A	228_I	0.664	0.99
96_L	99_V	0.661	0.99
165_G	169_D	0.661	0.99
44_R	76_E	0.654	0.99
221_T	225_M	0.653	0.99
119_I	125_D	0.649	0.99
91_S	204_S	0.647	0.99
119_I	123_D	0.645	0.98
161_Y	179_V	0.640	0.98
71_S	116_V	0.639	0.98
153_N	176_I	0.635	0.98
96_L	150_R	0.631	0.98
45_G	76_E	0.627	0.98
103_D	148_D	0.625	0.98
69_S	72_I	0.625	0.98
129_I	132_F	0.624	0.98
213_T	218_R	0.623	0.98
219_Q	222_F	0.623	0.98
144_A	231_E	0.621	0.98
141_A	231_E	0.620	0.98
99_V	105_V	0.618	0.98
128_A	132_F	0.616	0.98
53_Y	58_I	0.615	0.98
119_I	122_K	0.613	0.98
163_P	192_E	0.612	0.98
93_G	179_V	0.612	0.98
43_V	79_T	0.610	0.98
139_V	142_A	0.609	0.98
180_E	199_T	0.600	0.98
71_S	185_G	0.599	0.98
22_D	25_R	0.598	0.98
86_I	186_I	0.594	0.97
131_D	134_M	0.594	0.97
136_R	143_K	0.592	0.97
71_S	75_K	0.592	0.97
119_I	124_H	0.591	0.97
118_R	124_H	0.590	0.97
157_A	161_Y	0.588	0.97
223_N	226_I	0.588	0.97
86_I	195_A	0.588	0.97
88_R	91_S	0.583	0.97
166_E	171_M	0.582	0.97
129_I	191_A	0.564	0.96
200_I	229_A	0.562	0.96
20_P	29_I	0.559	0.96
181_M	205_D	0.559	0.96
138_A	142_A	0.558	0.96
24_L	27_K	0.556	0.96
31_E	223_N	0.556	0.96
26_A	30_A	0.553	0.96
100_K	148_D	0.553	0.96
64_G	188_G	0.552	0.96
19_M	186_I	0.551	0.96
33_F	227_K	0.548	0.96
116_V	189_V	0.546	0.96
132_F	138_A	0.545	0.96
171_M	174_Y	0.545	0.96
206_H	210_H	0.543	0.96
111_C	127_A	0.538	0.95
212_Q	215_A	0.537	0.95
104_V	221_T	0.536	0.95
24_L	42_N	0.534	0.95
111_C	114_S	0.533	0.95
179_V	205_D	0.531	0.95
107_G	130_A	0.530	0.95
183_A	201_C	0.528	0.95
20_P	62_G	0.527	0.95
33_F	223_N	0.527	0.95
24_L	217_E	0.526	0.95
44_R	193_F	0.525	0.95
212_Q	216_A	0.524	0.95
99_V	203_V	0.524	0.95
66_G	181_M	0.522	0.95
132_F	140_D	0.521	0.95
104_V	147_I	0.520	0.94
104_V	228_I	0.518	0.94
29_I	89_V	0.517	0.94
78_I	84_K	0.516	0.94
16_V	233_V	0.514	0.94
19_M	74_T	0.514	0.94
20_P	60_V	0.510	0.94
54_K	230_L	0.509	0.94
48_G	76_E	0.507	0.94
204_S	222_F	0.506	0.94
64_G	69_S	0.506	0.94
130_A	187_Y	0.504	0.94
110_A	114_S	0.504	0.94
51_G	59_S	0.503	0.93
37_A	49_F	0.501	0.93
51_G	58_I	0.500	0.93
160_F	211_E	0.500	0.93

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ldnA	3	0.9958	100	0.197	Contact Map
1odkA	3	0.9749	100	0.198	Contact Map
1je0A	3	0.9331	100	0.199	Contact Map
3phcA	5	0.9874	100	0.206	Contact Map
4mchA	3	0.9582	100	0.207	Contact Map
4lkrA	3	0.9749	100	0.21	Contact Map
1z34A	3	0.9623	100	0.212	Contact Map
4tymA	5	0.9791	100	0.213	Contact Map
2b94A	4	0.9498	100	0.214	Contact Map
3u40A	4	0.9749	100	0.215	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0086 seconds.