CYOB - ECOLI - GREMLIN Contacts

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CYOB - Cytochrome bo(3) ubiquinol oxidase subunit 1

UniProt:	P0ABI8	Sequences: MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWTYLWKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSLGVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHHFFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALGILCLVIQMYVSIRDRDQNRDLTGDPWGGRTLEWATSSPPPFYNFAVVPHVHERDAFWEMKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFSTIFGFAMIWHIWWLAIVGFAGMIITWIVKSFDEDVDYYVPVAEIEKLENQHFDEITKAGLKNGN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10179
Length:	663 (520)
Sequences:	3483 (1056)
Seq/√Len:	46.3

ECOLI - CYOB
BACSU - QOX1 COX1
HALSA - COX1
SULSO - Q97UN0 Q981A5 Q97VG9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
471_L	498_A	5.578	1.00
301_I	434_A	5.251	1.00
64_V	146_F	4.653	1.00
379_S	453_G	4.272	1.00
297_V	435_G	4.098	1.00
401_L	416_L	3.922	1.00
440_W	519_S	3.854	1.00
221_T	224_K	3.767	1.00
68_M	153_V	3.734	1.00
94_L	102_I	3.594	1.00
231_A	320_T	3.563	1.00
227_V	310_L	3.533	1.00
306_S	370_M	3.467	1.00
212_I	233_L	3.394	1.00
379_S	450_E	3.389	1.00
65_A	118_F	3.384	1.00
234_C	324_T	3.278	1.00
294_V	431_G	3.265	1.00
75_D	102_I	2.988	1.00
127_V	212_I	2.869	1.00
313_Y	317_V	2.820	1.00
59_I	125_L	2.819	1.00
337_T	411_H	2.701	1.00
213_L	222_M	2.668	1.00
370_M	381_M	2.639	1.00
222_M	225_M	2.606	1.00
422_N	465_F	2.587	1.00
168_T	187_V	2.545	1.00
304_T	438_Y	2.508	1.00
172_A	275_Y	2.495	1.00
326_L	355_I	2.456	1.00
466_V	501_G	2.391	1.00
451_T	455_R	2.370	1.00
305_F	438_Y	2.366	1.00
386_G	461_I	2.346	1.00
78_M	94_L	2.315	1.00
433_F	512_L	2.311	1.00
370_M	385_I	2.282	1.00
437_T	456_A	2.232	1.00
302_A	388_I	2.226	1.00
449_N	518_V	2.224	1.00
47_E	56_R	2.224	1.00
81_S	503_V	2.216	1.00
383_W	456_A	2.196	1.00
466_V	497_I	2.167	1.00
97_H	101_Q	2.162	1.00
450_E	454_K	2.160	1.00
526_N	529_L	2.149	1.00
356_A	399_V	2.144	1.00
442_K	545_S	2.133	1.00
463_G	504_L	2.115	1.00
194_L	250_V	2.052	0.99
108_V	190_W	2.041	0.99
96_P	484_S	2.010	0.99
492_H	496_M	2.004	0.99
459_F	508_G	2.000	0.99
126_V	438_Y	1.992	0.99
301_I	435_G	1.977	0.99
452_W	511_C	1.970	0.99
297_V	301_I	1.970	0.99
234_C	321_V	1.954	0.99
86_A	492_H	1.927	0.99
78_M	102_I	1.918	0.99
400_L	415_F	1.917	0.99
456_A	512_L	1.915	0.99
406_A	410_L	1.910	0.99
283_G	286_E	1.909	0.99
299_S	366_W	1.880	0.99
459_F	511_C	1.879	0.99
108_V	172_A	1.824	0.99
282_W	286_E	1.805	0.99
474_L	494_M	1.801	0.99
242_S	328_F	1.776	0.99
290_L	424_I	1.769	0.98
212_I	225_M	1.769	0.98
500_S	504_L	1.757	0.98
452_W	514_I	1.751	0.98
188_D	257_R	1.735	0.98
295_F	359_T	1.728	0.98
64_V	149_T	1.714	0.98
146_F	150_V	1.712	0.98
77_I	499_A	1.705	0.98
307_R	376_V	1.700	0.98
276_I	412_N	1.693	0.98
171_L	279_I	1.684	0.98
72_G	109_I	1.681	0.98
452_W	455_R	1.680	0.98
70_L	513_V	1.670	0.98
518_V	522_D	1.666	0.98
390_T	465_F	1.661	0.98
205_G	240_I	1.660	0.98
256_D	261_T	1.634	0.97
209_F	233_L	1.619	0.97
431_G	434_A	1.606	0.97
209_F	240_I	1.605	0.97
64_V	150_V	1.602	0.97
168_T	177_S	1.602	0.97
291_I	295_F	1.589	0.97
242_S	289_I	1.578	0.97
216_R	219_G	1.574	0.97
174_P	275_Y	1.565	0.97
130_Q	229_T	1.560	0.97
74_A	78_M	1.556	0.97
45_W	49_L	1.554	0.96
141_L	203_L	1.549	0.96
469_M	473_A	1.545	0.96
79_M	102_I	1.535	0.96
245_I	281_A	1.528	0.96
84_A	496_M	1.527	0.96
447_K	529_L	1.516	0.96
375_I	381_M	1.506	0.96
352_T	402_A	1.503	0.96
301_I	384_T	1.497	0.96
62_I	443_A	1.479	0.95
383_W	433_F	1.463	0.95
456_A	508_G	1.461	0.95
305_F	380_A	1.452	0.95
220_M	226_P	1.451	0.95
114_V	429_V	1.441	0.95
252_L	264_F	1.428	0.94
78_M	93_F	1.417	0.94
177_S	253_L	1.416	0.94
456_A	460_W	1.403	0.94
316_L	320_T	1.396	0.94
384_T	434_A	1.394	0.94
459_F	507_L	1.392	0.94
418_A	472_Y	1.366	0.93
302_A	370_M	1.364	0.93
518_V	527_R	1.353	0.93
436_M	512_L	1.351	0.92
316_L	319_A	1.349	0.92
543_T	551_N	1.347	0.92
479_M	495_L	1.346	0.92
500_S	503_V	1.327	0.92
212_I	229_T	1.318	0.92
220_M	225_M	1.315	0.91
98_H	102_I	1.312	0.91
239_I	243_F	1.312	0.91
126_V	443_A	1.309	0.91
544_S	547_P	1.304	0.91
550_Y	553_A	1.302	0.91
213_L	237_V	1.302	0.91
77_I	502_A	1.298	0.91
51_S	143_N	1.289	0.91
213_L	233_L	1.287	0.91
503_V	507_L	1.287	0.91
113_F	153_V	1.285	0.90
89_G	485_Q	1.281	0.90
467_A	505_I	1.279	0.90
323_I	362_K	1.271	0.90
386_G	457_F	1.269	0.90
228_F	232_S	1.264	0.90
295_F	360_G	1.261	0.90
426_G	464_F	1.250	0.89
451_T	454_K	1.248	0.89
291_I	427_G	1.245	0.89
249_T	275_Y	1.243	0.89
108_V	275_Y	1.242	0.89
382_L	457_F	1.239	0.89
297_V	439_W	1.236	0.89
172_A	177_S	1.234	0.89
143_N	147_W	1.231	0.88
218_P	555_V	1.225	0.88
77_I	506_A	1.222	0.88
305_F	381_M	1.219	0.88
379_S	454_K	1.216	0.88
303_A	310_L	1.216	0.88
48_W	60_M	1.199	0.87
166_A	190_W	1.197	0.87
437_T	453_G	1.194	0.87
168_T	172_A	1.193	0.87
262_H	265_T	1.190	0.87
113_F	197_S	1.185	0.86
301_I	380_A	1.183	0.86
174_P	177_S	1.183	0.86
514_I	518_V	1.183	0.86
51_S	56_R	1.181	0.86
422_N	469_M	1.180	0.86
441_P	447_K	1.180	0.86
544_S	548_P	1.179	0.86
506_A	510_L	1.177	0.86
66_I	70_L	1.176	0.86
174_P	253_L	1.176	0.86
545_S	548_P	1.172	0.86
446_F	526_N	1.169	0.86
238_L	352_T	1.169	0.86
446_F	519_S	1.167	0.86
560_E	563_A	1.164	0.85
127_V	229_T	1.160	0.85
543_T	547_P	1.156	0.85
456_A	509_I	1.150	0.85
115_A	424_I	1.142	0.84
59_I	443_A	1.141	0.84
460_W	508_G	1.135	0.84
71_R	157_N	1.130	0.84
295_F	366_W	1.129	0.84
255_L	261_T	1.127	0.84
172_A	187_V	1.124	0.83
152_G	193_S	1.123	0.83
127_V	131_I	1.123	0.83
349_G	404_P	1.119	0.83
241_A	328_F	1.119	0.83
473_A	494_M	1.110	0.83
543_T	552_F	1.109	0.83
45_W	60_M	1.105	0.82
465_F	469_M	1.105	0.82
436_M	516_M	1.103	0.82
171_L	411_H	1.103	0.82
105_A	160_L	1.102	0.82
234_C	320_T	1.099	0.82
460_W	505_I	1.097	0.82
433_F	456_A	1.097	0.82
119_V	432_C	1.097	0.82
298_F	387_F	1.094	0.82
298_F	302_A	1.090	0.81
383_W	437_T	1.090	0.81
370_M	375_I	1.087	0.81
217_A	555_V	1.087	0.81
223_F	318_W	1.086	0.81
124_N	207_N	1.085	0.81
58_G	121_G	1.081	0.81
467_A	502_A	1.077	0.81
71_R	109_I	1.075	0.81
480_T	483_L	1.074	0.80
120_I	205_G	1.066	0.80
493_T	497_I	1.066	0.80
46_K	50_T	1.059	0.80
537_R	562_D	1.058	0.79
356_A	362_K	1.047	0.79
158_V	189_Y	1.046	0.79
85_L	91_A	1.042	0.78
514_I	517_Y	1.037	0.78
299_S	362_K	1.036	0.78
62_I	118_F	1.030	0.78
235_A	289_I	1.026	0.77
43_Y	47_E	1.025	0.77
119_V	294_V	1.025	0.77
188_D	258_Y	1.024	0.77
291_I	428_V	1.022	0.77
198_G	247_T	1.020	0.77
109_I	157_N	1.019	0.77
116_M	283_G	1.017	0.77
99_Y	103_F	1.014	0.76
77_I	503_V	1.012	0.76
362_K	366_W	1.009	0.76
380_A	438_Y	1.009	0.76
317_V	320_T	1.007	0.76
510_L	514_I	1.007	0.76
195_Q	250_V	1.004	0.76
422_N	472_Y	1.003	0.76
231_A	292_L	1.003	0.76
337_T	408_F	1.003	0.76
125_L	443_A	1.002	0.76
532_D	536_G	1.000	0.75
496_M	500_S	0.998	0.75
205_G	236_N	0.996	0.75
414_L	479_M	0.994	0.75
97_H	167_Q	0.988	0.75
219_G	224_K	0.988	0.75
305_F	534_W	0.985	0.74
201_T	239_I	0.982	0.74
112_F	282_W	0.982	0.74
352_T	401_L	0.979	0.74
124_N	142_N	0.975	0.74
138_F	210_V	0.972	0.73
224_K	558_V	0.971	0.73
450_E	453_G	0.970	0.73
227_V	316_L	0.970	0.73
123_M	232_S	0.964	0.73
132_G	539_L	0.964	0.73
362_K	365_N	0.961	0.73
69_L	114_V	0.956	0.72
71_R	75_D	0.953	0.72
471_L	474_L	0.953	0.72
316_L	365_N	0.953	0.72
399_V	402_A	0.951	0.72
222_M	233_L	0.950	0.72
83_Q	495_L	0.949	0.72
380_A	448_L	0.948	0.71
72_G	111_I	0.943	0.71
145_S	204_T	0.942	0.71
562_D	565_W	0.942	0.71
156_V	193_S	0.938	0.71
53_D	56_R	0.933	0.70
307_R	535_G	0.933	0.70
353_M	402_A	0.929	0.70
529_L	545_S	0.929	0.70
313_Y	453_G	0.928	0.70
377_F	385_I	0.927	0.70
172_A	190_W	0.926	0.70
528_D	545_S	0.924	0.70
69_L	76_A	0.922	0.69
440_W	448_L	0.919	0.69
145_S	203_L	0.917	0.69
209_F	237_V	0.917	0.69
547_P	552_F	0.916	0.69
379_S	382_L	0.910	0.68
94_L	98_H	0.908	0.68
42_T	46_K	0.907	0.68
456_A	511_C	0.907	0.68
83_Q	414_L	0.906	0.68
115_A	429_V	0.904	0.68
531_G	544_S	0.897	0.67
115_A	290_L	0.896	0.67
48_W	56_R	0.896	0.67
149_T	200_G	0.895	0.67
446_F	520_I	0.894	0.67
152_G	228_F	0.892	0.67
447_K	530_T	0.891	0.67
216_R	224_K	0.891	0.67
286_E	290_L	0.890	0.67
462_I	504_L	0.889	0.67
453_G	515_Q	0.885	0.66
449_N	452_W	0.884	0.66
470_P	494_M	0.884	0.66
243_F	286_E	0.882	0.66
463_G	508_G	0.879	0.66
225_M	229_T	0.875	0.65
199_I	203_L	0.875	0.65
195_Q	251_A	0.873	0.65
382_L	454_K	0.873	0.65
197_S	200_G	0.872	0.65
517_Y	521_R	0.871	0.65
414_L	495_L	0.868	0.65
208_F	212_I	0.867	0.65
111_I	115_A	0.867	0.65
82_Q	485_Q	0.866	0.64
66_I	513_V	0.865	0.64
131_I	229_T	0.864	0.64
359_T	362_K	0.862	0.64
424_I	428_V	0.857	0.64
40_K	43_Y	0.857	0.64
162_V	499_A	0.857	0.64
301_I	431_G	0.851	0.63
82_Q	92_G	0.850	0.63
79_M	107_G	0.847	0.63
226_P	229_T	0.846	0.63
295_F	362_K	0.845	0.63
202_T	247_T	0.844	0.62
132_G	217_A	0.844	0.62
115_A	428_V	0.843	0.62
60_M	146_F	0.841	0.62
234_C	237_V	0.839	0.62
282_W	290_L	0.839	0.62
136_V	149_T	0.837	0.62
262_H	268_M	0.837	0.62
530_T	545_S	0.833	0.61
302_A	306_S	0.833	0.61
144_L	148_F	0.832	0.61
283_G	290_L	0.831	0.61
310_L	313_Y	0.831	0.61
243_F	283_G	0.831	0.61
62_I	121_G	0.829	0.61
237_V	324_T	0.828	0.61
255_L	259_L	0.828	0.61
305_F	378_H	0.823	0.60
401_L	410_L	0.823	0.60
81_S	499_A	0.822	0.60
295_F	319_A	0.816	0.60
220_M	536_G	0.815	0.60
81_S	93_F	0.813	0.60
327_S	412_N	0.811	0.59
118_F	433_F	0.809	0.59
498_A	501_G	0.809	0.59
364_F	386_G	0.807	0.59
114_V	118_F	0.802	0.58
116_M	286_E	0.801	0.58
377_F	381_M	0.792	0.58
120_I	123_M	0.792	0.58
243_F	282_W	0.792	0.58
325_V	329_I	0.791	0.57
315_S	411_H	0.791	0.57
121_G	246_L	0.789	0.57
560_E	564_F	0.786	0.57
345_N	408_F	0.777	0.56
73_F	509_I	0.774	0.56
141_L	145_S	0.774	0.56
387_F	423_V	0.774	0.56
239_I	286_E	0.774	0.56
440_W	444_F	0.772	0.56
119_V	289_I	0.772	0.56
67_V	71_R	0.772	0.56
195_Q	254_T	0.771	0.55
298_F	384_T	0.770	0.55
366_W	387_F	0.766	0.55
315_S	319_A	0.764	0.55
400_L	406_A	0.763	0.55
456_A	515_Q	0.761	0.55
127_V	232_S	0.756	0.54
111_I	290_L	0.755	0.54
249_T	279_I	0.755	0.54
460_W	509_I	0.749	0.53
390_T	461_I	0.749	0.53
191_I	254_T	0.747	0.53
432_C	436_M	0.746	0.53
56_R	60_M	0.744	0.53
497_I	501_G	0.743	0.53
416_L	420_F	0.743	0.53
389_V	393_V	0.742	0.53
442_K	531_G	0.742	0.53
379_S	383_W	0.740	0.52
200_G	271_N	0.740	0.52
418_A	471_L	0.740	0.52
277_N	335_F	0.739	0.52
349_G	403_V	0.739	0.52
462_I	466_V	0.738	0.52
116_M	282_W	0.737	0.52
499_A	503_V	0.736	0.52
378_H	438_Y	0.734	0.52
341_G	345_N	0.733	0.52
291_I	366_W	0.732	0.52
198_G	362_K	0.732	0.52
332_L	340_A	0.731	0.52
503_V	506_A	0.730	0.51
119_V	144_L	0.728	0.51
218_P	313_Y	0.728	0.51
126_V	130_Q	0.725	0.51
105_A	166_A	0.725	0.51
444_F	447_K	0.723	0.51
463_G	501_G	0.723	0.51
69_L	429_V	0.723	0.51
206_I	210_V	0.722	0.51
277_N	472_Y	0.721	0.51
433_F	460_W	0.719	0.50
70_L	74_A	0.719	0.50
442_K	543_T	0.716	0.50
89_G	93_F	0.715	0.50
256_D	355_I	0.715	0.50
120_I	239_I	0.714	0.50
459_F	504_L	0.713	0.50
119_V	428_V	0.713	0.50
64_V	153_V	0.712	0.50
208_F	232_S	0.712	0.50
397_T	401_L	0.712	0.50
252_L	263_F	0.710	0.49
124_N	135_D	0.710	0.49
455_R	511_C	0.708	0.49
76_A	426_G	0.706	0.49
306_S	415_F	0.706	0.49
123_M	208_F	0.706	0.49
449_N	514_I	0.705	0.49
238_L	290_L	0.703	0.49
122_L	297_V	0.703	0.49
85_L	496_M	0.703	0.49
311_F	362_K	0.703	0.49
466_V	504_L	0.700	0.49
335_F	412_N	0.700	0.49
513_V	517_Y	0.699	0.48
306_S	375_I	0.698	0.48
363_I	388_I	0.698	0.48
116_M	239_I	0.695	0.48
363_I	392_S	0.695	0.48
319_A	322_C	0.691	0.48
414_L	499_A	0.691	0.48
141_L	206_I	0.690	0.48
424_I	427_G	0.690	0.48
405_G	424_I	0.689	0.47
104_T	108_V	0.689	0.47
140_F	271_N	0.686	0.47
219_G	450_E	0.686	0.47
73_F	506_A	0.685	0.47
445_G	547_P	0.685	0.47
178_G	181_Y	0.684	0.47
304_T	538_T	0.684	0.47
291_I	424_I	0.683	0.47
353_M	366_W	0.683	0.47
256_D	262_H	0.682	0.47
125_L	149_T	0.682	0.47
76_A	103_F	0.681	0.47
239_I	283_G	0.681	0.47
299_S	356_A	0.680	0.47
225_M	233_L	0.680	0.47
177_S	275_Y	0.679	0.46
382_L	458_W	0.679	0.46
532_D	535_G	0.678	0.46
237_V	322_C	0.678	0.46
73_F	76_A	0.676	0.46
442_K	534_W	0.676	0.46
433_F	437_T	0.675	0.46
136_V	208_F	0.674	0.46
54_H	129_L	0.674	0.46
291_I	423_V	0.673	0.46
376_V	535_G	0.673	0.46
83_Q	486_Q	0.672	0.46
311_F	323_I	0.671	0.46
370_M	373_G	0.671	0.46
442_K	547_P	0.671	0.46
54_H	137_A	0.671	0.46
171_L	412_N	0.670	0.46
231_A	310_L	0.669	0.45
428_V	432_C	0.667	0.45
154_I	158_V	0.666	0.45
529_L	533_P	0.666	0.45
306_S	381_M	0.665	0.45
136_V	355_I	0.664	0.45
360_G	399_V	0.664	0.45
243_F	317_V	0.664	0.45
433_F	509_I	0.662	0.45
392_S	396_M	0.661	0.45
116_M	201_T	0.661	0.45
290_L	428_V	0.661	0.45
121_G	432_C	0.660	0.45
298_F	431_G	0.660	0.45
381_M	396_M	0.659	0.44
254_T	258_Y	0.659	0.44
79_M	99_Y	0.658	0.44
373_G	534_W	0.658	0.44
100_D	117_P	0.657	0.44
100_D	414_L	0.657	0.44
447_K	519_S	0.656	0.44
195_Q	247_T	0.656	0.44
238_L	319_A	0.655	0.44
486_Q	491_F	0.655	0.44
223_F	310_L	0.654	0.44
316_L	361_V	0.653	0.44
227_V	480_T	0.653	0.44
379_S	386_G	0.653	0.44
449_N	519_S	0.650	0.44
380_A	447_K	0.650	0.44
99_Y	102_I	0.650	0.44
114_V	232_S	0.650	0.44
534_W	545_S	0.650	0.44
378_H	454_K	0.649	0.44
218_P	545_S	0.647	0.43
119_V	297_V	0.645	0.43
483_L	495_L	0.645	0.43
219_G	453_G	0.644	0.43
367_L	371_Y	0.640	0.43
273_M	412_N	0.640	0.43
206_I	411_H	0.640	0.43
176_L	286_E	0.639	0.43
526_N	530_T	0.639	0.43
205_G	242_S	0.639	0.43
511_C	515_Q	0.638	0.42
216_R	220_M	0.637	0.42
201_T	320_T	0.637	0.42
291_I	362_K	0.637	0.42
217_A	220_M	0.636	0.42
370_M	438_Y	0.635	0.42
250_V	254_T	0.633	0.42
118_F	432_C	0.632	0.42
442_K	450_E	0.632	0.42
444_F	519_S	0.632	0.42
239_I	282_W	0.632	0.42
383_W	455_R	0.631	0.42
447_K	526_N	0.629	0.42
158_V	497_I	0.629	0.42
113_F	152_G	0.628	0.41
371_Y	534_W	0.628	0.41
304_T	534_W	0.627	0.41
488_D	492_H	0.626	0.41
166_A	187_V	0.626	0.41
277_N	412_N	0.625	0.41
126_V	396_M	0.625	0.41
236_N	289_I	0.622	0.41
272_M	276_I	0.620	0.41
396_M	426_G	0.620	0.41
208_F	352_T	0.619	0.41
454_K	458_W	0.619	0.41
124_N	330_V	0.617	0.40
112_F	290_L	0.616	0.40
251_A	494_M	0.616	0.40
105_A	190_W	0.615	0.40
338_M	412_N	0.614	0.40
176_L	239_I	0.614	0.40
373_G	533_P	0.613	0.40
308_K	362_K	0.612	0.40
168_T	174_P	0.610	0.40
383_W	512_L	0.610	0.40
447_K	533_P	0.609	0.40
144_L	203_L	0.609	0.40
448_L	516_M	0.608	0.40
52_V	143_N	0.607	0.39
219_G	539_L	0.607	0.39
70_L	383_W	0.607	0.39
41_W	45_W	0.606	0.39
299_S	353_M	0.605	0.39
405_G	410_L	0.605	0.39
531_G	543_T	0.604	0.39
67_V	154_I	0.603	0.39
159_S	162_V	0.603	0.39
114_V	384_T	0.603	0.39
381_M	384_T	0.602	0.39
40_K	47_E	0.602	0.39
528_D	531_G	0.602	0.39
399_V	406_A	0.601	0.39
81_S	306_S	0.601	0.39
273_M	338_M	0.600	0.39
234_C	326_L	0.600	0.39
135_D	142_N	0.599	0.39
397_T	420_F	0.599	0.39
125_L	383_W	0.598	0.39
194_L	246_L	0.598	0.39
95_P	98_H	0.597	0.39
112_F	423_V	0.597	0.39
336_F	405_G	0.596	0.38
249_T	519_S	0.594	0.38
142_N	211_T	0.593	0.38
234_C	282_W	0.593	0.38
151_V	154_I	0.593	0.38
201_T	272_M	0.592	0.38
44_L	47_E	0.592	0.38
192_W	251_A	0.591	0.38
111_I	116_M	0.591	0.38
200_G	309_R	0.591	0.38
109_I	153_V	0.591	0.38
508_G	538_T	0.589	0.38
79_M	499_A	0.589	0.38
55_K	551_N	0.588	0.38
118_F	436_M	0.586	0.38
417_I	476_F	0.585	0.37
394_G	423_V	0.584	0.37
495_L	499_A	0.583	0.37
159_S	166_A	0.582	0.37
145_S	208_F	0.580	0.37
322_C	547_P	0.580	0.37
237_V	321_V	0.580	0.37
352_T	522_D	0.579	0.37
61_Y	360_G	0.577	0.37
388_I	469_M	0.577	0.37
167_Q	182_S	0.576	0.37
407_D	416_L	0.576	0.37
459_F	496_M	0.576	0.37
356_A	359_T	0.576	0.37
486_Q	492_H	0.576	0.37
290_L	317_V	0.575	0.37
561_R	564_F	0.575	0.37
85_L	89_G	0.574	0.36
303_A	533_P	0.574	0.36
305_F	373_G	0.573	0.36
442_K	552_F	0.573	0.36
380_A	434_A	0.573	0.36
236_N	508_G	0.572	0.36
70_L	509_I	0.571	0.36
313_Y	534_W	0.571	0.36
302_A	469_M	0.571	0.36
216_R	255_L	0.570	0.36
311_F	365_N	0.569	0.36
377_F	438_Y	0.568	0.36
363_I	423_V	0.568	0.36
63_I	154_I	0.568	0.36
136_V	204_T	0.567	0.36
267_D	317_V	0.567	0.36
122_L	210_V	0.566	0.36
289_I	402_A	0.566	0.36
41_W	44_L	0.566	0.36
66_I	516_M	0.565	0.36
72_G	107_G	0.565	0.36
441_P	519_S	0.565	0.36
336_F	404_P	0.565	0.36
114_V	436_M	0.564	0.36
63_I	402_A	0.563	0.35
221_T	273_M	0.563	0.35
63_I	66_I	0.562	0.35
357_I	484_S	0.561	0.35
392_S	427_G	0.560	0.35
137_A	211_T	0.560	0.35
192_W	196_L	0.558	0.35
327_S	509_I	0.557	0.35
349_G	498_A	0.555	0.35
141_L	210_V	0.554	0.35
169_G	226_P	0.554	0.35
511_C	514_I	0.554	0.35
207_N	362_K	0.554	0.35
386_G	430_F	0.552	0.34
137_A	215_M	0.552	0.34
324_T	372_Q	0.551	0.34
248_V	252_L	0.551	0.34
152_G	197_S	0.551	0.34
102_I	399_V	0.551	0.34
115_A	432_C	0.550	0.34
150_V	154_I	0.550	0.34
296_G	299_S	0.549	0.34
134_R	555_V	0.549	0.34
142_N	323_I	0.548	0.34
271_N	274_M	0.548	0.34
227_V	411_H	0.548	0.34
73_F	77_I	0.547	0.34
413_S	491_F	0.547	0.34
208_F	236_N	0.547	0.34
435_G	521_R	0.547	0.34
216_R	544_S	0.547	0.34
458_W	462_I	0.547	0.34
264_F	541_W	0.545	0.34
328_F	392_S	0.544	0.34
302_A	384_T	0.544	0.34
146_F	149_T	0.544	0.34
114_V	433_F	0.543	0.34
329_I	541_W	0.543	0.34
183_P	388_I	0.543	0.34
59_I	63_I	0.543	0.34
441_P	449_N	0.542	0.34
234_C	286_E	0.541	0.33
291_I	299_S	0.541	0.33
312_G	365_N	0.540	0.33
219_G	533_P	0.540	0.33
440_W	446_F	0.540	0.33
83_Q	499_A	0.538	0.33
202_T	264_F	0.537	0.33
308_K	311_F	0.537	0.33
193_S	197_S	0.537	0.33
390_T	413_S	0.537	0.33
81_S	240_I	0.537	0.33
305_F	548_P	0.537	0.33
191_I	275_Y	0.536	0.33
188_D	283_G	0.535	0.33
210_V	240_I	0.535	0.33
449_N	522_D	0.535	0.33
112_F	392_S	0.533	0.33
352_T	420_F	0.533	0.33
437_T	515_Q	0.533	0.33
155_L	189_Y	0.532	0.33
379_S	458_W	0.532	0.33
54_H	58_G	0.531	0.33
303_A	405_G	0.531	0.33
350_I	406_A	0.530	0.33
442_K	544_S	0.529	0.32
387_F	418_A	0.529	0.32
70_L	451_T	0.528	0.32
221_T	548_P	0.528	0.32
302_A	316_L	0.528	0.32
155_L	327_S	0.528	0.32
57_L	142_N	0.527	0.32
59_I	85_L	0.526	0.32
76_A	425_I	0.525	0.32
294_V	298_F	0.524	0.32
522_D	527_R	0.524	0.32
466_V	470_P	0.523	0.32
471_L	483_L	0.523	0.32
335_F	472_Y	0.523	0.32
121_G	152_G	0.523	0.32
317_V	532_D	0.523	0.32
435_G	503_V	0.522	0.32
247_T	362_K	0.522	0.32
75_D	160_L	0.521	0.32
62_I	491_F	0.521	0.32
132_G	442_K	0.521	0.32
160_L	275_Y	0.520	0.32
116_M	243_F	0.520	0.32
48_W	51_S	0.520	0.32
198_G	207_N	0.520	0.32
72_G	454_K	0.519	0.32
392_S	413_S	0.519	0.32
259_L	374_R	0.518	0.31
296_G	366_W	0.517	0.31
129_L	548_P	0.517	0.31
380_A	452_W	0.517	0.31
217_A	224_K	0.516	0.31
433_F	436_M	0.516	0.31
43_Y	46_K	0.515	0.31
75_D	157_N	0.515	0.31
77_I	91_A	0.514	0.31
55_K	142_N	0.514	0.31
388_I	561_R	0.512	0.31
49_L	400_L	0.512	0.31
342_A	380_A	0.512	0.31
434_A	541_W	0.512	0.31
249_T	426_G	0.512	0.31
337_T	500_S	0.511	0.31
207_N	330_V	0.511	0.31
136_V	252_L	0.511	0.31
323_I	359_T	0.510	0.31
391_F	427_G	0.510	0.31
46_K	51_S	0.509	0.31
515_Q	519_S	0.508	0.31
309_R	314_T	0.508	0.31
373_G	453_G	0.507	0.31
462_I	510_L	0.507	0.31
214_K	340_A	0.506	0.30
44_L	49_L	0.505	0.30
76_A	464_F	0.504	0.30
479_M	486_Q	0.503	0.30
341_G	344_V	0.503	0.30
442_K	533_P	0.502	0.30
107_G	420_F	0.502	0.30
543_T	548_P	0.501	0.30
39_G	43_Y	0.501	0.30
174_P	407_D	0.500	0.30
349_G	508_G	0.500	0.30
193_S	252_L	0.500	0.30

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1fftA	1	0.7511	100	0.2	Contact Map
2yevA	1	0.911	100	0.315	Contact Map
2gsmA	1	0.7526	100	0.362	Contact Map
1v54A	1	0.7722	100	0.37	Contact Map
3s8fA	1	0.7798	100	0.487	Contact Map
3ayfA	2	0.7376	100	0.505	Contact Map
3mk7A	1	0.6637	100	0.532	Contact Map
3wfdB	1	0.6365	100	0.539	Contact Map
1v54C	1	0.1192	97.1	0.973	Contact Map
1qleC	1	0.1176	97	0.973	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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