GREMLIN Database
FTSA - Cell division protein FtsA
UniProt: P0ABH0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10339
Length: 420 (338)
Sequences: 8167 (4630)
Seq/√Len: 251.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
154_M181_K4.0121.00
242_D299_P3.8811.00
231_V303_E3.7381.00
255_E259_V3.5131.00
209_V304_L3.0611.00
18_A213_G2.8851.00
346_A350_R2.7481.00
378_T382_L2.7151.00
379_A382_L2.6301.00
360_A363_N2.5031.00
243_I288_L2.4771.00
338_A341_I2.4741.00
292_T295_E2.4541.00
220_V311_E2.4491.00
379_A383_L2.4131.00
176_E181_K2.3921.00
380_V383_L2.3721.00
17_T214_G2.3591.00
378_T383_L2.2961.00
158_V369_D2.2941.00
377_S380_V2.2701.00
298_E302_T2.2581.00
301_Y343_G2.2281.00
256_A260_R2.2211.00
84_S87_H2.2171.00
20_V140_Q2.1651.00
246_A296_V2.1571.00
207_C218_I2.1301.00
289_Q292_T2.1061.00
239_V300_R2.0951.00
43_S46_M2.0921.00
211_I239_V2.0771.00
239_V301_Y2.0681.00
85_G88_I2.0301.00
377_S383_L2.0251.00
135_Y138_D2.0171.00
207_C220_V1.9961.00
377_S382_L1.9911.00
141_E145_N1.9721.00
377_S381_G1.9661.00
345_A357_R1.9481.00
23_L370_Y1.9351.00
253_D256_A1.9201.00
347_C350_R1.9131.00
305_L351_V1.9021.00
309_N351_V1.8861.00
169_K173_K1.8841.00
87_H90_C1.8831.00
378_T381_G1.8091.00
242_D300_R1.7951.00
274_S287_S1.7941.00
297_I301_Y1.7911.00
84_S88_I1.7891.00
142_G146_P1.7801.00
211_I216_M1.7791.00
205_G222_T1.7721.00
247_F254_A1.7691.00
236_G338_A1.7471.00
293_L341_I1.7451.00
11_V22_A1.7311.00
90_C95_G1.7231.00
53_D56_S1.7191.00
247_F286_R1.7151.00
280_V283_R1.6871.00
244_A251_P1.6491.00
157_K175_V1.6471.00
246_A292_T1.6361.00
272_D287_S1.6331.00
243_I254_A1.6011.00
294_A346_A1.5971.00
15_I171_I1.5871.00
244_A254_A1.5851.00
154_M183_D1.5841.00
242_D297_I1.5791.00
290_R294_A1.5611.00
8_K154_M1.5591.00
86_K90_C1.5471.00
297_I341_I1.5411.00
60_C237_N1.5141.00
239_V293_L1.5001.00
241_S251_P1.4851.00
127_V132_P1.4841.00
305_L309_N1.4801.00
305_L344_L1.4781.00
302_T347_C1.4671.00
239_V297_I1.4571.00
310_E321_Q1.4571.00
309_N320_R1.4411.00
10_V183_D1.4301.00
332_I352_F1.4241.00
134_E177_R1.4201.00
22_A64_A1.4051.00
93_E96_M1.3881.00
76_I79_V1.3851.00
343_G346_A1.3821.00
139_Y143_I1.3781.00
49_G53_D1.3701.00
204_L331_G1.3601.00
306_N309_N1.3541.00
306_N310_E1.3531.00
220_V329_A1.3311.00
234_Y238_V1.2841.00
15_I137_I1.2841.00
243_I293_L1.2801.00
301_Y347_C1.2781.00
253_D257_I1.2741.00
297_I300_R1.2701.00
276_E285_P1.2621.00
172_V185_L1.2611.00
214_G217_D1.2401.00
90_C94_I1.2341.00
37_G49_G1.2341.00
204_L330_A1.2321.00
242_D245_Y1.2081.00
85_G90_C1.2071.00
216_M304_L1.2021.00
188_A217_D1.2011.00
133_Q171_I1.1981.00
92_N96_M1.1911.00
279_S282_G1.1851.00
211_I344_L1.1851.00
10_V373_E1.1841.00
81_L84_S1.1831.00
78_S82_A1.1781.00
73_D76_I1.1691.00
257_I288_L1.1671.00
298_E343_G1.1611.00
295_E298_E1.1531.00
205_G324_V1.1451.00
127_V135_Y1.1431.00
239_V338_A1.1331.00
293_L338_A1.1301.00
240_T258_K1.1291.00
343_G347_C1.1141.00
88_I91_Q1.1121.00
38_V135_Y1.1081.00
279_S283_R1.1071.00
62_Q66_D1.1061.00
241_S245_Y1.1051.00
159_H185_L1.1051.00
372_Q375_Y1.1011.00
140_Q143_I1.0981.00
82_A85_G1.0981.00
95_G98_P1.0951.00
174_A178_C1.0891.00
83_L88_I1.0861.00
79_V84_S1.0831.00
187_F190_L1.0811.00
46_M49_G1.0801.00
307_L311_E1.0721.00
273_E277_V1.0661.00
77_S80_Y1.0641.00
340_Q362_L1.0491.00
291_Q295_E1.0441.00
218_I311_E1.0311.00
42_P46_M1.0301.00
33_V36_I1.0281.00
278_P283_R1.0271.00
33_V38_V1.0171.00
86_K98_P1.0161.00
257_I275_V1.0111.00
168_A187_F1.0091.00
276_E279_S1.0081.00
197_L200_D1.0071.00
276_E280_V1.0071.00
172_V176_E1.0031.00
249_T277_V1.0021.00
143_I146_P1.0011.00
90_C97_V1.0001.00
186_I191_A0.9951.00
305_L348_A0.9951.00
290_R342_E0.9931.00
257_I273_E0.9891.00
94_I97_V0.9831.00
78_S183_D0.9821.00
302_T306_N0.9781.00
88_I95_G0.9781.00
23_L366_G0.9781.00
73_D79_V0.9761.00
277_V280_V0.9761.00
141_E180_L0.9721.00
173_K176_E0.9661.00
345_A349_Q0.9631.00
93_E98_P0.9581.00
308_V348_A0.9541.00
167_M170_N0.9531.00
93_E97_V0.9511.00
240_T255_E0.9411.00
74_C77_S0.9401.00
163_C167_M0.9391.00
138_D142_G0.9331.00
249_T253_D0.9271.00
349_Q355_Q0.9231.00
334_L348_A0.9221.00
38_V41_C0.9211.00
239_V341_I0.9211.00
220_V324_V0.9181.00
34_N38_V0.9171.00
160_L163_C0.9171.00
305_L308_V0.9151.00
21_A31_G0.9111.00
258_K338_A0.9071.00
220_V322_Q0.9051.00
82_A88_I0.9041.00
79_V82_A0.9041.00
272_D278_P0.9011.00
325_K328_L0.9001.00
173_K177_R0.8971.00
91_Q95_G0.8931.00
61_V133_Q0.8921.00
340_Q373_E0.8911.00
61_V174_A0.8871.00
79_V85_G0.8861.00
22_A140_Q0.8851.00
262_G297_I0.8841.00
301_Y304_L0.8831.00
175_V182_V0.8811.00
255_E258_K0.8801.00
211_I304_L0.8751.00
346_A349_Q0.8711.00
83_L90_C0.8650.99
161_I171_I0.8630.99
273_E278_P0.8600.99
83_L87_H0.8600.99
249_T278_P0.8590.99
331_G356_V0.8570.99
292_T296_V0.8490.99
87_H91_Q0.8400.99
166_D170_N0.8390.99
9_L150_S0.8370.99
305_L347_C0.8350.99
86_K95_G0.8340.99
83_L86_K0.8310.99
79_V87_H0.8280.99
246_A288_L0.8270.99
347_C351_V0.8270.99
82_A86_K0.8240.99
30_D363_N0.8200.99
175_V185_L0.8170.99
278_P282_G0.8150.99
205_G330_A0.8150.99
86_K89_S0.8150.99
76_I83_L0.8130.99
31_G34_N0.8130.99
12_G383_L0.8130.99
304_L307_L0.8120.99
276_E282_G0.8100.99
85_G93_E0.8090.99
84_S90_C0.8090.99
272_D277_V0.8090.99
87_H95_G0.8070.99
358_I361_P0.8060.99
55_E86_K0.8050.99
131_I177_R0.8040.99
91_Q96_M0.8010.99
364_I368_T0.8010.99
320_R325_K0.8010.99
356_V364_I0.8000.99
74_C80_Y0.8000.99
85_G89_S0.7960.99
229_T307_L0.7950.99
324_V328_L0.7900.99
96_M99_I0.7880.99
26_E34_N0.7880.99
11_V155_Q0.7870.99
303_E307_L0.7860.99
224_G227_R0.7850.99
79_V90_C0.7810.99
79_V83_L0.7810.99
303_E306_N0.7800.99
206_V333_V0.7800.99
374_P381_G0.7730.99
92_N95_G0.7700.99
25_G374_P0.7690.99
298_E347_C0.7650.99
214_G236_G0.7630.99
357_R360_A0.7620.99
76_I88_I0.7620.99
58_V61_V0.7610.99
161_I217_D0.7600.99
189_G217_D0.7600.99
211_I338_A0.7570.99
53_D57_V0.7570.99
76_I84_S0.7540.99
247_F288_L0.7530.99
98_P126_R0.7520.99
288_L293_L0.7510.99
276_E283_R0.7510.99
243_I246_A0.7510.99
319_L326_H0.7420.98
58_V132_P0.7410.98
131_I135_Y0.7390.98
77_S81_L0.7380.98
80_Y86_K0.7370.98
85_G92_N0.7350.98
211_I339_A0.7320.98
273_E283_R0.7320.98
274_S280_V0.7300.98
165_N169_K0.7300.98
89_S93_E0.7300.98
159_H187_F0.7290.98
31_G35_I0.7280.98
273_E281_G0.7260.98
100_S124_E0.7250.98
46_M50_G0.7220.98
302_T351_V0.7200.98
86_K91_Q0.7180.98
81_L85_G0.7170.98
14_E214_G0.7140.98
192_S213_G0.7140.98
81_L175_V0.7090.98
63_R66_D0.7090.98
159_H168_A0.7080.98
270_G273_E0.7080.98
274_S277_V0.7060.98
83_L89_S0.7050.98
80_Y83_L0.7030.98
229_T311_E0.7010.98
230_K311_E0.7010.98
46_M57_V0.6950.98
49_G52_N0.6930.98
76_I82_A0.6890.97
311_E322_Q0.6890.97
300_R303_E0.6890.97
76_I80_Y0.6890.97
21_A366_G0.6890.97
90_C96_M0.6830.97
183_D376_Y0.6800.97
209_V216_M0.6800.97
237_N251_P0.6790.97
310_E320_R0.6770.97
236_G258_K0.6760.97
263_C270_G0.6760.97
31_G36_I0.6740.97
92_N97_V0.6740.97
207_C308_V0.6740.97
78_S81_L0.6740.97
189_G219_A0.6730.97
11_V152_V0.6720.97
274_S283_R0.6700.97
42_P45_G0.6690.97
249_T280_V0.6690.97
80_Y88_I0.6660.97
334_L344_L0.6660.97
335_T364_I0.6620.97
80_Y87_H0.6610.97
17_T215_T0.6590.97
302_T305_L0.6520.97
210_D214_G0.6500.96
34_N41_C0.6490.96
243_I248_G0.6460.96
156_A373_E0.6450.96
62_Q65_I0.6440.96
33_V37_G0.6410.96
72_A79_V0.6400.96
274_S285_P0.6400.96
219_A226_L0.6390.96
48_K52_N0.6370.96
311_E321_Q0.6350.96
241_S244_A0.6350.96
38_V127_V0.6320.96
209_V218_I0.6310.96
238_V241_S0.6290.96
235_A238_V0.6280.96
372_Q376_Y0.6260.96
79_V88_I0.6250.96
88_I98_P0.6230.95
79_V86_K0.6220.95
245_Y248_G0.6220.95
90_C93_E0.6210.95
130_V173_K0.6210.95
247_F275_V0.6210.95
192_S335_T0.6150.95
272_D282_G0.6140.95
190_L194_Y0.6140.95
233_P238_V0.6130.95
74_C78_S0.6120.95
78_S83_L0.6120.95
75_Q79_V0.6120.95
13_L175_V0.6110.95
98_P124_E0.6100.95
86_K92_N0.6080.95
301_Y344_L0.6080.95
209_V230_K0.6080.95
138_D151_G0.6080.95
277_V281_G0.6080.95
297_I343_G0.6070.95
213_G217_D0.6070.95
184_Q372_Q0.6050.95
194_Y372_Q0.6050.95
365_T368_T0.6040.95
8_K27_V0.6020.95
61_V64_A0.6010.95
47_D52_N0.6010.95
157_K171_I0.6000.94
193_S221_Y0.5990.94
309_N326_H0.5980.94
14_E210_D0.5960.94
366_G369_D0.5960.94
161_I189_G0.5940.94
260_R270_G0.5920.94
79_V180_L0.5910.94
168_A185_L0.5910.94
146_P149_L0.5910.94
24_V147_V0.5890.94
210_D217_D0.5870.94
249_T279_S0.5840.94
76_I90_C0.5840.94
15_I133_Q0.5830.94
88_I96_M0.5820.94
92_N159_H0.5820.94
130_V138_D0.5790.93
368_T371_A0.5780.93
85_G91_Q0.5780.93
356_V359_G0.5770.93
81_L86_K0.5770.93
208_V333_V0.5760.93
302_T350_R0.5760.93
81_L88_I0.5750.93
271_K274_S0.5750.93
345_A358_I0.5750.93
50_G53_D0.5750.93
74_C79_V0.5750.93
24_V148_G0.5750.93
52_N55_E0.5730.93
271_K278_P0.5720.93
308_V351_V0.5720.93
87_H93_E0.5680.93
274_S282_G0.5680.93
64_A97_V0.5670.93
334_L357_R0.5660.93
144_K148_G0.5640.92
76_I85_G0.5600.92
11_V24_V0.5590.92
273_E279_S0.5580.92
260_R273_E0.5570.92
326_H353_H0.5560.92
164_H167_M0.5560.92
189_G215_T0.5550.92
77_S82_A0.5550.92
161_I214_G0.5540.92
36_I39_G0.5540.92
252_S256_A0.5530.92
277_V283_R0.5520.92
188_A213_G0.5500.92
93_E99_I0.5490.91
95_G99_I0.5480.91
88_I93_E0.5480.91
88_I97_V0.5460.91
256_A259_V0.5460.91
189_G192_S0.5460.91
242_D296_V0.5440.91
272_D280_V0.5440.91
32_M38_V0.5430.91
257_I293_L0.5420.91
51_V252_S0.5400.91
75_Q80_Y0.5400.91
45_G51_V0.5400.91
297_I338_A0.5400.91
44_R56_S0.5380.91
278_P281_G0.5370.91
61_V136_A0.5340.90
308_V352_F0.5330.90
61_V132_P0.5330.90
169_K172_V0.5330.90
254_A259_V0.5310.90
94_I98_P0.5310.90
12_G23_L0.5300.90
32_M37_G0.5290.90
277_V282_G0.5290.90
301_Y341_I0.5280.90
13_L157_K0.5260.90
33_V46_M0.5260.90
145_N151_G0.5250.90
152_V155_Q0.5230.89
142_G145_N0.5230.89
85_G97_V0.5220.89
294_A343_G0.5190.89
247_F284_P0.5190.89
138_D141_E0.5170.89
261_H290_R0.5170.89
270_G277_V0.5160.89
72_A76_I0.5140.89
13_L22_A0.5140.89
79_V91_Q0.5120.88
46_M53_D0.5110.88
216_M307_L0.5100.88
14_E17_T0.5090.88
247_F257_I0.5080.88
168_A172_V0.5070.88
60_C63_R0.5060.88
229_T321_Q0.5060.88
65_I171_I0.5050.88
76_I81_L0.5050.88
77_S83_L0.5050.88
58_V99_I0.5040.88
73_D77_S0.5030.88
91_Q97_V0.5030.88
249_T257_I0.5030.88
145_N152_V0.5020.87
363_N368_T0.5020.87
96_M153_R0.5010.87
84_S91_Q0.5010.87
19_K259_V0.5010.87
263_C290_R0.5010.87
79_V95_G0.5000.87
60_C65_I0.5000.87
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3wqtA 2 0.8571 100 0.352 Contact Map
4a2aA 1 0.8738 100 0.358 Contact Map
3d2fA 1 0.9 100 0.375 Contact Map
4jneA 2 0.8952 100 0.39 Contact Map
4fl9A 1 0.8881 100 0.391 Contact Map
3wt0A 1 0.8786 100 0.393 Contact Map
2v7yA 1 0.8357 100 0.416 Contact Map
3i33A 1 0.7952 100 0.419 Contact Map
4kboA 1 0.7881 100 0.425 Contact Map
4rtfD 1 0.7262 100 0.431 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0116 seconds.