GREMLIN Database
RODA - Rod shape-determining protein RodA
UniProt: P0ABG7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10607
Length: 370 (349)
Sequences: 8029 (5547)
Seq/√Len: 296.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
291_G311_M3.7181.00
17_D290_R3.6361.00
291_G356_V3.4601.00
104_D107_I3.1841.00
172_F312_L3.1471.00
95_I100_Q2.8631.00
28_L53_I2.7851.00
23_I286_L2.7291.00
216_D219_S2.6651.00
269_A277_I2.6531.00
68_P303_G2.6171.00
220_D223_G2.6021.00
82_C119_A2.5561.00
307_A356_V2.5251.00
235_I269_A2.5171.00
63_M351_A2.4741.00
78_L119_A2.3741.00
24_L353_F2.3521.00
56_G350_M2.3101.00
23_I287_L2.2011.00
41_Q47_E2.1981.00
310_L356_V2.1201.00
268_L280_L2.0941.00
265_F277_I2.0591.00
82_C116_A2.0361.00
176_L308_G2.0181.00
151_T163_S2.0141.00
338_L353_F1.9951.00
288_I315_F1.9941.00
258_E261_T1.9591.00
60_M357_M1.9451.00
338_L349_L1.9191.00
34_V268_L1.9111.00
32_A46_M1.8921.00
218_E229_I1.8861.00
97_K258_E1.8761.00
173_V309_G1.8481.00
88_A103_L1.8451.00
44_G48_R1.8311.00
34_V272_L1.8121.00
293_W297_R1.7921.00
104_D109_R1.7921.00
88_A92_F1.7471.00
323_G329_L1.7401.00
245_W272_L1.7381.00
221_P229_I1.7251.00
152_L156_A1.7241.00
147_I170_G1.7191.00
72_E302_F1.7101.00
228_I331_V1.7081.00
324_M331_V1.6881.00
278_L282_A1.6631.00
291_G307_A1.6621.00
318_V322_I1.6391.00
310_L352_G1.6291.00
30_Y268_L1.6271.00
50_I54_A1.6131.00
298_A359_I1.6091.00
209_Q224_A1.6091.00
303_G359_I1.5671.00
248_G267_V1.5671.00
113_S162_T1.5611.00
37_S271_E1.5541.00
122_L306_M1.5441.00
32_A49_K1.5371.00
307_A359_I1.5301.00
89_V103_L1.5211.00
94_A104_D1.5201.00
281_L322_I1.5191.00
86_L116_A1.5161.00
80_I84_I1.5101.00
74_W77_Y1.4911.00
243_K249_T1.4751.00
47_E50_I1.4731.00
230_Q250_Q1.4701.00
128_I173_V1.4671.00
241_R275_V1.4661.00
265_F322_I1.4631.00
110_F115_I1.4571.00
28_L350_M1.4421.00
295_A307_A1.4361.00
165_L334_V1.4181.00
94_A109_R1.4111.00
268_L339_V1.4111.00
38_A267_V1.3961.00
84_I88_A1.3891.00
169_S313_I1.3881.00
59_I351_A1.3711.00
121_P309_G1.3701.00
30_Y280_L1.3641.00
284_Y318_V1.3561.00
288_I318_V1.3531.00
335_P345_A1.3531.00
52_Q343_G1.3531.00
204_H207_Q1.3441.00
23_I283_L1.3421.00
205_D208_R1.3401.00
314_L349_L1.3381.00
173_V305_V1.3371.00
54_A58_V1.3311.00
120_V166_V1.3281.00
60_M354_G1.3281.00
300_T303_G1.3271.00
24_L350_M1.3261.00
77_Y81_I1.3211.00
79_Y150_P1.3201.00
34_V264_I1.3091.00
358_S362_H1.2961.00
36_W46_M1.2841.00
53_I346_L1.2831.00
288_I311_M1.2771.00
240_L274_L1.2741.00
136_S139_N1.2681.00
126_R130_R1.2681.00
248_G271_E1.2651.00
154_V166_V1.2641.00
225_G229_I1.2611.00
20_M287_L1.2611.00
228_I327_G1.2601.00
168_L316_V1.2561.00
274_L278_L1.2491.00
83_I149_M1.2401.00
32_A50_I1.2391.00
45_M260_H1.2351.00
208_R212_M1.2271.00
203_M207_Q1.2261.00
125_A173_V1.2071.00
205_D209_Q1.2041.00
124_V170_G1.1971.00
185_G189_V1.1871.00
101_R113_S1.1861.00
47_E51_G1.1821.00
294_I307_A1.1791.00
263_F331_V1.1711.00
233_I250_Q1.1681.00
231_S325_V1.1671.00
58_V62_V1.1641.00
114_E117_K1.1641.00
27_L339_V1.1621.00
180_S183_L1.1611.00
87_V91_A1.1601.00
220_D224_A1.1561.00
20_M294_I1.1531.00
36_W43_I1.1461.00
121_P169_S1.1451.00
68_P358_S1.1431.00
71_Y355_I1.1351.00
116_A150_P1.1351.00
89_V112_P1.1321.00
287_L353_F1.1281.00
148_F152_L1.1171.00
33_L245_W1.1151.00
72_E129_N1.1051.00
76_P80_I1.0961.00
45_M341_Y1.0911.00
145_V149_M1.0911.00
226_Y257_P1.0911.00
281_L318_V1.0881.00
72_E126_R1.0821.00
294_I360_H1.0811.00
311_M356_V1.0811.00
70_V73_G1.0801.00
292_L311_M1.0801.00
75_A126_R1.0791.00
19_T286_L1.0761.00
96_S109_R1.0761.00
306_M359_I1.0691.00
237_S243_K1.0651.00
209_Q212_M1.0601.00
74_W78_L1.0591.00
16_L21_L1.0581.00
55_M347_I1.0551.00
187_A191_V1.0521.00
68_P300_T1.0481.00
21_L357_M1.0451.00
256_L266_A1.0451.00
313_I352_G1.0421.00
64_A354_G1.0361.00
202_L205_D1.0361.00
121_P313_I1.0291.00
115_I348_V1.0251.00
56_G346_L1.0201.00
35_I38_A1.0171.00
186_V190_L1.0161.00
230_Q233_I1.0151.00
122_L302_F1.0141.00
357_M360_H1.0121.00
280_L339_V1.0091.00
240_L275_V1.0021.00
196_P200_F0.9981.00
60_M63_M0.9941.00
124_V143_A0.9881.00
162_T335_P0.9881.00
289_M293_W0.9881.00
226_Y230_Q0.9831.00
64_A358_S0.9811.00
77_Y80_I0.9811.00
317_Y345_A0.9801.00
57_L61_V0.9771.00
261_T341_Y0.9761.00
22_L26_A0.9681.00
190_L194_F0.9661.00
164_I168_L0.9661.00
220_D225_G0.9621.00
317_Y335_P0.9581.00
76_P123_M0.9551.00
232_K327_G0.9521.00
27_L287_L0.9511.00
44_G47_E0.9481.00
49_K52_Q0.9461.00
127_F143_A0.9451.00
75_A302_F0.9431.00
213_M224_A0.9431.00
175_F181_W0.9351.00
48_R51_G0.9331.00
30_Y283_L0.9291.00
136_S142_I0.9281.00
68_P359_I0.9241.00
48_R52_Q0.9171.00
19_T290_R0.9161.00
26_A283_L0.9161.00
79_Y83_I0.9161.00
101_R161_G0.9141.00
295_A311_M0.9131.00
161_G324_M0.9131.00
161_G332_V0.9101.00
314_L318_V0.9101.00
83_I150_P0.9061.00
231_S266_A0.9061.00
268_L272_L0.9051.00
118_I351_A0.9031.00
301_T304_R0.9021.00
308_G312_L0.9011.00
67_P70_V0.8971.00
62_V66_I0.8961.00
295_A308_G0.8901.00
120_V147_I0.8831.00
218_E232_K0.8821.00
128_I177_S0.8761.00
83_I87_V0.8761.00
356_V359_I0.8761.00
27_L280_L0.8741.00
89_V100_Q0.8741.00
193_A196_P0.8701.00
306_M355_I0.8641.00
64_A361_T0.8641.00
48_R341_Y0.8531.00
141_G145_V0.8531.00
35_I264_I0.8511.00
285_I289_M0.8511.00
324_M332_V0.8511.00
138_K142_I0.8501.00
282_A286_L0.8451.00
118_I348_V0.8411.00
151_T167_A0.8391.00
60_M353_F0.8391.00
217_P229_I0.8371.00
43_I46_M0.8361.00
160_L207_Q0.8351.00
345_A349_L0.8321.00
336_L339_V0.8321.00
260_H341_Y0.8281.00
191_V195_I0.8251.00
70_V74_W0.8251.00
75_A119_A0.8251.00
228_I231_S0.8211.00
167_A171_L0.8201.00
244_G271_E0.8191.00
121_P310_L0.8161.00
79_Y123_M0.8161.00
56_G354_G0.8141.00
199_W202_L0.8141.00
30_Y34_V0.8121.00
56_G347_I0.8101.00
63_M71_Y0.8071.00
209_Q213_M0.8071.00
118_I352_G0.8051.00
118_I355_I0.8041.00
284_Y336_L0.8031.00
155_A163_S0.8031.00
319_F328_I0.8011.00
159_D162_T0.8011.00
181_W185_G0.8001.00
104_D108_V0.7991.00
29_V33_L0.7991.00
184_I188_V0.7981.00
213_M219_S0.7950.99
25_L29_V0.7950.99
37_S244_G0.7950.99
277_I326_S0.7940.99
354_G358_S0.7930.99
183_L187_A0.7930.99
41_Q44_G0.7910.99
217_P225_G0.7900.99
259_R267_V0.7870.99
323_G328_I0.7860.99
231_S263_F0.7860.99
52_Q347_I0.7840.99
110_F344_S0.7830.99
123_M146_L0.7820.99
121_P173_V0.7820.99
46_M50_I0.7810.99
139_N142_I0.7780.99
176_L312_L0.7750.99
85_L89_V0.7730.99
277_I281_L0.7710.99
302_F306_M0.7690.99
169_S172_F0.7690.99
307_A311_M0.7660.99
28_L57_L0.7660.99
43_I47_E0.7640.99
60_M350_M0.7630.99
86_L153_L0.7630.99
358_S361_T0.7630.99
265_F280_L0.7620.99
51_G54_A0.7610.99
90_D156_A0.7610.99
99_A157_Q0.7530.99
110_F348_V0.7530.99
24_L287_L0.7510.99
93_G100_Q0.7480.99
128_I143_A0.7460.99
160_L164_I0.7460.99
235_I326_S0.7440.99
66_I71_Y0.7390.99
263_F325_V0.7370.99
256_L259_R0.7350.99
61_V65_Q0.7340.99
324_M329_L0.7330.99
267_V271_E0.7310.99
59_I347_I0.7280.99
154_V162_T0.7230.99
290_R293_W0.7220.99
322_I326_S0.7220.99
36_W246_L0.7220.99
125_A129_N0.7200.99
85_L110_F0.7190.99
87_V153_L0.7190.99
355_I359_I0.7150.99
131_D139_N0.7110.99
227_H231_S0.7070.99
201_F208_R0.7060.99
213_M217_P0.7040.99
232_K236_G0.7040.99
303_G306_M0.7030.99
228_I263_F0.7030.99
265_F336_L0.6990.99
67_P303_G0.6970.99
216_D225_G0.6950.99
233_I236_G0.6950.99
264_I268_L0.6940.99
69_R300_T0.6920.99
349_L352_G0.6910.99
125_A302_F0.6890.99
23_I290_R0.6870.99
140_T144_L0.6860.99
264_I339_V0.6850.98
57_L60_M0.6850.98
287_L314_L0.6840.98
298_A303_G0.6840.98
172_F316_V0.6840.98
35_I49_K0.6820.98
80_I83_I0.6810.98
116_A119_A0.6740.98
206_Y209_Q0.6720.98
185_G188_V0.6720.98
292_L312_L0.6710.98
19_T23_I0.6690.98
115_I351_A0.6680.98
90_D100_Q0.6680.98
320_V329_L0.6660.98
160_L204_H0.6650.98
76_P126_R0.6640.98
68_P306_M0.6630.98
143_A170_G0.6610.98
287_L291_G0.6600.98
189_V193_A0.6580.98
213_M225_G0.6580.98
131_D134_P0.6570.98
105_L109_R0.6570.98
168_L172_F0.6560.98
97_K100_Q0.6560.98
212_M220_D0.6550.98
229_I233_I0.6530.98
211_V215_L0.6530.98
99_A158_P0.6510.98
85_L115_I0.6480.98
123_M127_F0.6470.98
286_L290_R0.6460.98
282_A285_I0.6460.98
353_F356_V0.6460.98
248_G270_E0.6420.98
284_Y338_L0.6410.98
344_S348_V0.6370.98
322_I336_L0.6370.98
312_L316_V0.6350.98
45_M48_R0.6320.97
125_A309_G0.6310.97
56_G59_I0.6300.97
272_L276_G0.6290.97
59_I62_V0.6280.97
219_S225_G0.6270.97
147_I151_T0.6250.97
124_V147_I0.6230.97
230_Q257_P0.6230.97
55_M58_V0.6200.97
297_R360_H0.6180.97
140_T174_L0.6180.97
131_D142_I0.6170.97
301_T305_V0.6140.97
213_M220_D0.6100.97
91_A100_Q0.6100.97
111_Q114_E0.6070.97
218_E225_G0.6070.97
128_I305_V0.6070.97
121_P306_M0.6050.97
101_R158_P0.6020.97
62_V65_Q0.6020.97
310_L359_I0.5990.97
97_K260_H0.5990.97
298_A307_A0.5960.96
137_L141_G0.5930.96
72_E300_T0.5920.96
89_V157_Q0.5920.96
280_L284_Y0.5920.96
23_I282_A0.5910.96
142_I145_V0.5890.96
320_V324_M0.5880.96
137_L183_L0.5880.96
183_L186_V0.5870.96
65_Q361_T0.5850.96
52_Q56_G0.5850.96
86_L89_V0.5840.96
15_H361_T0.5820.96
212_M216_D0.5820.96
125_A306_M0.5810.96
88_A91_A0.5790.96
49_K53_I0.5770.96
292_L296_A0.5770.96
128_I174_L0.5770.96
349_L353_F0.5750.96
55_M59_I0.5740.96
119_A123_M0.5730.96
166_V170_G0.5700.95
291_G353_F0.5700.95
279_I282_A0.5690.95
177_S305_V0.5680.95
86_L154_V0.5680.95
348_V352_G0.5660.95
18_P22_L0.5650.95
30_Y339_V0.5640.95
82_C115_I0.5610.95
68_P362_H0.5610.95
244_G270_E0.5570.95
291_G294_I0.5560.95
94_A100_Q0.5560.95
315_F318_V0.5550.95
153_L157_Q0.5540.95
191_V194_F0.5540.95
20_M353_F0.5540.95
72_E130_R0.5530.95
26_A29_V0.5530.95
319_F329_L0.5510.94
294_I298_A0.5490.94
199_W203_M0.5490.94
321_N325_V0.5490.94
91_A94_A0.5480.94
207_Q211_V0.5470.94
122_L355_I0.5460.94
220_D226_Y0.5450.94
49_K346_L0.5440.94
212_M219_S0.5440.94
229_I232_K0.5440.94
350_M354_G0.5430.94
101_R334_V0.5430.94
52_Q55_M0.5420.94
196_P201_F0.5420.94
90_D94_A0.5400.94
64_A357_M0.5390.94
265_F281_L0.5370.94
20_M290_R0.5360.94
319_F323_G0.5340.94
79_Y146_L0.5330.93
310_L313_I0.5320.93
214_L217_P0.5310.93
279_I283_L0.5300.93
194_F198_L0.5260.93
126_R302_F0.5250.93
234_A256_L0.5240.93
105_L108_V0.5240.93
287_L356_V0.5230.93
32_A53_I0.5220.93
213_M228_I0.5220.93
69_R72_E0.5210.93
125_A305_V0.5210.93
101_R162_T0.5200.93
73_G77_Y0.5190.93
256_L267_V0.5190.93
236_G274_L0.5190.93
283_L286_L0.5180.92
127_F131_D0.5180.92
94_A97_K0.5170.92
204_H208_R0.5170.92
127_F146_L0.5140.92
123_M131_D0.5130.92
231_S256_L0.5130.92
132_V301_T0.5120.92
169_S173_V0.5120.92
27_L31_S0.5110.92
198_L202_L0.5110.92
63_M354_G0.5110.92
179_L184_I0.5100.92
53_I350_M0.5100.92
17_D360_H0.5080.92
115_I119_A0.5070.92
96_S104_D0.5070.92
188_V192_A0.5050.92
23_I26_A0.5040.91
86_L158_P0.5030.91
146_L150_P0.5020.91
284_Y339_V0.5020.91
101_R166_V0.5020.91
286_L289_M0.5020.91
89_V93_G0.5000.91
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4qncA 2 0.2054 14.9 0.969 Contact Map
4x5mA 2 0.2351 12.7 0.97 Contact Map
3wajA 1 0.7541 9.5 0.972 Contact Map
4ev6A 3 0.1892 7.9 0.973 Contact Map
4i0uA 4 0.1838 7.8 0.973 Contact Map
3l1lA 2 0.3378 5.9 0.974 Contact Map
2l6wA 2 0.0946 4.3 0.976 Contact Map
3aqpA 1 0.4946 4.2 0.976 Contact Map
3j01B 1 0.1514 3.8 0.976 Contact Map
2m20A 2 0.0973 3.5 0.977 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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