YEAV - ECOLI - GREMLIN Contacts

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YEAV - Uncharacterized transporter YeaV

UniProt:	P0ABD1	Sequences: MVLLAMGLVIYLATSKYGNIRLGEGKPEYSTLSWLFMFICAGLGSSTLYWGVAEWAYYYQTPGLNIAPRSQQALEFSVPYSFFHWGISAWATYTLASLIMAYHFHVRKNKGLSLSGIIAAITGVRPQGPWGKLVDLMFLIATVGALTISLVVTAATFTRGLSALTGLPDNFTVQAFVILLSGGIFCLSSWIGINNGLQRLSKMVGWGAFLLPLLVLIVGPTEFITNSIINAIGLTTQNFLQMSLFTDPLGDGSFTRNWTVFYWLWWISYTPGVAMFVTRVSRGRKIKEVIWGLILGSTVGCWFFFGVMESYAIHQFINGVINVPQVLETLGGETAVQQVLMSLPAGKLFLAAYLGVMIIFLASHMDAVAYTMAATSTRNLQEGDDPDRGLRLFWCVVITLIPLSILFTGASLETMKTTVVLTALPFLVILLVKVGGFIRWLKQDYADIPAHQVEHYLPQTPVEALEKTPVLPAGTVFKGDN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13508
Length:	481 (439)
Sequences:	3288 (1918)
Seq/√Len:	91.5

ECOLI - YEAV BETT CAIT
BACSU - OPUD
HALSA - Q9HQN5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
21_R	26_K	4.605	1.00
139_L	376_S	4.018	1.00
316_F	322_N	3.459	1.00
214_L	218_V	3.422	1.00
214_L	349_F	3.411	1.00
25_G	282_R	3.157	1.00
175_A	403_L	2.946	1.00
70_S	73_A	2.841	1.00
314_H	318_N	2.716	1.00
188_S	366_D	2.657	1.00
311_Y	343_L	2.599	1.00
118_I	134_V	2.587	1.00
228_I	306_G	2.565	1.00
172_T	176_F	2.531	1.00
322_N	325_Q	2.505	1.00
59_Y	317_I	2.488	1.00
216_L	307_V	2.473	1.00
212_P	307_V	2.439	1.00
216_L	225_T	2.433	1.00
122_T	126_P	2.430	1.00
286_I	441_L	2.383	1.00
215_V	343_L	2.379	1.00
13_A	290_I	2.372	1.00
8_L	434_V	2.360	1.00
33_S	202_K	2.352	1.00
29_Y	194_N	2.331	1.00
82_F	302_W	2.295	1.00
358_I	362_A	2.294	1.00
191_I	199_R	2.258	1.00
158_T	169_D	2.226	1.00
4_L	431_L	2.197	1.00
182_G	399_T	2.197	1.00
13_A	291_W	2.158	1.00
187_L	191_I	2.147	1.00
338_Q	341_M	2.146	1.00
11_Y	438_I	2.132	1.00
8_L	438_I	2.105	1.00
365_M	398_I	2.094	1.00
124_V	127_Q	2.089	1.00
190_W	392_L	2.088	1.00
67_A	70_S	2.087	1.00
424_L	428_V	2.081	1.00
227_S	310_S	2.038	1.00
30_S	33_S	2.031	1.00
186_C	190_W	2.009	1.00
158_T	177_V	1.981	1.00
268_S	419_V	1.968	1.00
110_K	119_A	1.915	1.00
208_A	360_F	1.913	1.00
122_T	130_W	1.900	1.00
17_Y	442_K	1.892	1.00
129_P	133_L	1.891	1.00
228_I	303_F	1.876	1.00
16_K	19_N	1.875	1.00
119_A	127_Q	1.865	1.00
56_A	316_F	1.854	1.00
340_L	353_Y	1.854	1.00
230_N	248_P	1.854	1.00
186_C	395_C	1.849	1.00
128_G	131_G	1.841	1.00
363_S	367_A	1.840	1.00
15_S	18_G	1.827	1.00
206_W	210_L	1.819	1.00
5_A	430_L	1.795	1.00
340_L	349_F	1.784	1.00
158_T	173_V	1.781	1.00
176_F	180_L	1.781	1.00
117_I	433_K	1.777	1.00
220_P	224_I	1.772	1.00
237_Q	241_Q	1.771	1.00
171_F	407_F	1.766	1.00
7_G	11_Y	1.757	1.00
25_G	107_R	1.756	1.00
369_A	395_C	1.740	1.00
162_S	169_D	1.738	1.00
428_V	432_V	1.736	1.00
365_M	369_A	1.722	1.00
36_F	40_C	1.720	1.00
50_W	53_A	1.678	1.00
253_S	257_N	1.676	1.00
89_A	266_W	1.657	1.00
373_A	390_L	1.653	1.00
158_T	174_Q	1.648	1.00
21_R	24_E	1.646	1.00
315_Q	342_S	1.632	1.00
115_S	132_K	1.621	1.00
216_L	221_T	1.620	1.00
238_N	241_Q	1.617	1.00
40_C	359_I	1.605	1.00
31_T	288_E	1.598	1.00
18_G	287_K	1.581	1.00
56_A	323_V	1.578	1.00
319_G	322_N	1.565	1.00
199_R	203_M	1.558	1.00
228_I	302_W	1.549	1.00
137_M	429_I	1.545	1.00
179_L	403_L	1.537	1.00
50_W	332_G	1.527	1.00
4_L	434_V	1.525	1.00
86_G	298_T	1.522	1.00
183_G	187_L	1.520	1.00
431_L	435_G	1.509	1.00
167_L	173_V	1.497	1.00
190_W	388_R	1.490	1.00
11_Y	15_S	1.486	1.00
6_M	10_I	1.474	1.00
345_A	348_L	1.462	1.00
171_F	174_Q	1.460	1.00
336_V	353_Y	1.452	0.99
5_A	434_V	1.452	0.99
12_L	286_I	1.452	0.99
122_T	432_V	1.443	0.99
162_S	168_P	1.434	0.99
119_A	124_V	1.423	0.99
209_F	213_L	1.410	0.99
203_M	206_W	1.408	0.99
98_L	286_I	1.408	0.99
3_L	244_L	1.406	0.99
186_C	392_L	1.404	0.99
59_Y	69_R	1.403	0.99
74_L	317_I	1.394	0.99
356_V	359_I	1.390	0.99
79_P	238_N	1.388	0.99
33_S	198_Q	1.374	0.99
179_L	183_G	1.370	0.99
6_M	239_F	1.368	0.99
170_N	173_V	1.366	0.99
316_F	321_I	1.361	0.99
154_A	177_V	1.350	0.99
324_P	328_E	1.346	0.99
14_T	291_W	1.339	0.99
152_V	261_F	1.338	0.99
323_V	327_L	1.336	0.99
79_P	234_L	1.333	0.99
198_Q	202_K	1.327	0.99
298_T	302_W	1.326	0.99
231_A	306_G	1.314	0.99
96_A	433_K	1.310	0.99
229_I	233_G	1.308	0.99
396_V	400_L	1.306	0.99
79_P	242_M	1.300	0.99
348_L	351_A	1.290	0.99
388_R	391_R	1.290	0.99
129_P	132_K	1.289	0.99
121_I	435_G	1.287	0.99
93_Y	266_W	1.281	0.99
311_Y	339_V	1.276	0.99
88_S	243_S	1.275	0.99
14_T	287_K	1.269	0.99
168_P	173_V	1.260	0.99
32_L	205_G	1.256	0.99
161_L	173_V	1.254	0.99
369_A	398_I	1.253	0.99
5_A	95_L	1.251	0.98
423_A	427_L	1.237	0.98
158_T	170_N	1.234	0.98
413_E	416_K	1.233	0.98
364_H	367_A	1.233	0.98
6_M	91_A	1.233	0.98
29_Y	279_R	1.231	0.98
119_A	126_P	1.229	0.98
191_I	195_N	1.225	0.98
99_I	433_K	1.217	0.98
123_G	128_G	1.213	0.98
236_T	240_L	1.210	0.98
158_T	168_P	1.207	0.98
181_S	358_I	1.182	0.98
68_P	73_A	1.181	0.98
405_I	418_T	1.175	0.98
338_Q	342_S	1.174	0.98
220_P	314_H	1.169	0.98
299_V	303_F	1.162	0.98
21_R	285_K	1.158	0.97
173_V	176_F	1.151	0.97
224_I	307_V	1.149	0.97
163_A	341_M	1.149	0.97
203_M	359_I	1.144	0.97
28_E	194_N	1.139	0.97
240_L	243_S	1.138	0.97
43_L	89_A	1.136	0.97
200_L	366_D	1.126	0.97
438_I	442_K	1.125	0.97
49_Y	333_E	1.119	0.97
171_F	175_A	1.116	0.97
105_H	112_L	1.112	0.97
88_S	235_T	1.112	0.97
32_L	36_F	1.106	0.97
43_L	301_C	1.105	0.97
116_G	119_A	1.104	0.97
20_I	441_L	1.102	0.97
75_E	230_N	1.099	0.97
17_Y	438_I	1.098	0.97
130_W	133_L	1.096	0.96
108_K	440_W	1.096	0.96
347_K	351_A	1.096	0.96
316_F	319_G	1.094	0.96
99_I	437_F	1.094	0.96
189_S	395_C	1.088	0.96
6_M	87_I	1.085	0.96
94_T	293_L	1.083	0.96
110_K	126_P	1.079	0.96
52_V	335_A	1.072	0.96
10_I	14_T	1.068	0.96
393_F	397_V	1.066	0.96
6_M	88_S	1.066	0.96
115_S	185_F	1.065	0.96
225_T	229_I	1.064	0.96
232_I	302_W	1.050	0.96
189_S	193_I	1.046	0.95
269_Y	364_H	1.046	0.95
62_P	68_P	1.045	0.95
35_L	296_G	1.042	0.95
184_I	362_A	1.041	0.95
72_Q	75_E	1.039	0.95
295_L	299_V	1.037	0.95
137_M	422_T	1.034	0.95
15_S	20_I	1.034	0.95
160_G	337_Q	1.033	0.95
213_L	217_I	1.021	0.95
29_Y	37_M	1.020	0.95
87_I	91_A	1.020	0.95
125_R	128_G	1.020	0.95
426_F	429_I	1.017	0.95
270_T	430_L	1.017	0.95
179_L	396_V	1.004	0.94
97_S	289_V	1.002	0.94
3_L	88_S	1.000	0.94
110_K	116_G	1.000	0.94
227_S	231_A	0.999	0.94
72_Q	76_F	0.997	0.94
146_L	197_L	0.997	0.94
123_G	131_G	0.997	0.94
175_A	179_L	0.996	0.94
120_A	123_G	0.993	0.94
323_V	335_A	0.991	0.94
185_F	395_C	0.991	0.94
223_F	317_I	0.989	0.94
69_R	73_A	0.984	0.94
351_A	355_G	0.980	0.94
325_Q	328_E	0.972	0.93
237_Q	240_L	0.963	0.93
78_V	231_A	0.963	0.93
178_I	402_P	0.962	0.93
161_L	165_T	0.959	0.93
316_F	324_P	0.959	0.93
277_V	293_L	0.959	0.93
104_F	440_W	0.957	0.93
180_L	184_I	0.949	0.92
43_L	47_T	0.942	0.92
231_A	234_L	0.941	0.92
226_N	246_T	0.939	0.92
437_F	441_L	0.938	0.92
148_I	416_K	0.933	0.92
13_A	18_G	0.932	0.92
87_I	294_I	0.932	0.92
343_L	348_L	0.931	0.92
31_T	35_L	0.927	0.92
53_A	254_F	0.927	0.92
334_T	338_Q	0.920	0.91
80_Y	242_M	0.919	0.91
360_F	364_H	0.910	0.91
148_I	415_M	0.907	0.91
163_A	334_T	0.905	0.91
58_Y	254_F	0.903	0.90
392_L	396_V	0.901	0.90
323_V	328_E	0.901	0.90
8_L	95_L	0.899	0.90
199_R	202_K	0.897	0.90
148_I	405_I	0.894	0.90
50_W	152_V	0.894	0.90
67_A	73_A	0.890	0.90
84_H	259_T	0.889	0.90
376_S	390_L	0.887	0.90
112_L	115_S	0.886	0.90
231_A	310_S	0.885	0.90
29_Y	33_S	0.883	0.89
184_I	187_L	0.881	0.89
149_S	153_T	0.878	0.89
126_P	131_G	0.876	0.89
326_V	338_Q	0.876	0.89
218_V	349_F	0.872	0.89
182_G	185_F	0.872	0.89
146_L	368_V	0.871	0.89
372_M	398_I	0.867	0.89
200_L	359_I	0.867	0.89
3_L	243_S	0.866	0.88
233_G	244_L	0.865	0.88
439_R	443_Q	0.863	0.88
91_A	94_T	0.862	0.88
102_Y	444_D	0.859	0.88
193_I	370_Y	0.857	0.88
195_N	199_R	0.857	0.88
119_A	125_R	0.855	0.88
45_S	153_T	0.851	0.88
51_G	305_F	0.850	0.88
36_F	205_G	0.847	0.87
108_K	444_D	0.845	0.87
346_G	350_L	0.842	0.87
59_Y	70_S	0.842	0.87
71_Q	317_I	0.840	0.87
38_F	364_H	0.839	0.87
374_A	386_P	0.835	0.87
45_S	149_S	0.831	0.86
230_N	234_L	0.830	0.86
52_V	339_V	0.830	0.86
263_W	266_W	0.830	0.86
295_L	298_T	0.828	0.86
175_A	407_F	0.826	0.86
189_S	391_R	0.825	0.86
316_F	320_V	0.820	0.86
345_A	349_F	0.819	0.86
233_G	246_T	0.816	0.85
150_L	361_L	0.815	0.85
111_G	116_G	0.814	0.85
57_Y	61_T	0.813	0.85
340_L	350_L	0.802	0.84
33_S	36_F	0.801	0.84
69_R	72_Q	0.799	0.84
74_L	249_L	0.799	0.84
162_S	167_L	0.798	0.84
82_F	231_A	0.796	0.84
218_V	343_L	0.796	0.84
327_L	331_G	0.795	0.84
45_S	361_L	0.794	0.84
398_I	402_P	0.794	0.84
40_C	201_S	0.792	0.84
191_I	194_N	0.791	0.84
345_A	351_A	0.790	0.83
188_S	201_S	0.788	0.83
202_K	366_D	0.788	0.83
293_L	296_G	0.786	0.83
239_F	243_S	0.771	0.82
64_L	76_F	0.770	0.82
46_S	85_W	0.767	0.82
221_T	224_I	0.766	0.82
223_F	310_S	0.764	0.81
204_V	363_S	0.764	0.81
318_N	322_N	0.763	0.81
65_N	68_P	0.762	0.81
238_N	242_M	0.762	0.81
215_V	311_Y	0.762	0.81
113_S	379_N	0.762	0.81
306_G	311_Y	0.761	0.81
223_F	314_H	0.760	0.81
53_A	332_G	0.760	0.81
118_I	432_V	0.759	0.81
37_M	280_V	0.759	0.81
122_T	436_G	0.758	0.81
369_A	373_A	0.757	0.81
20_I	107_R	0.757	0.81
8_L	12_L	0.755	0.81
316_F	323_V	0.754	0.81
21_R	288_E	0.754	0.81
12_L	98_L	0.753	0.80
326_V	330_L	0.752	0.80
182_G	361_L	0.750	0.80
121_I	130_W	0.749	0.80
224_I	303_F	0.749	0.80
209_F	300_G	0.748	0.80
86_G	302_W	0.746	0.80
86_G	89_A	0.746	0.80
47_T	149_S	0.745	0.80
210_L	348_L	0.744	0.80
51_G	304_F	0.742	0.79
194_N	199_R	0.741	0.79
373_A	386_P	0.741	0.79
151_V	261_F	0.741	0.79
188_S	200_L	0.741	0.79
164_L	351_A	0.741	0.79
172_T	179_L	0.739	0.79
331_G	334_T	0.739	0.79
81_S	305_F	0.738	0.79
107_R	444_D	0.738	0.79
161_L	167_L	0.737	0.79
3_L	240_L	0.736	0.79
388_R	392_L	0.731	0.78
210_L	214_L	0.730	0.78
214_L	345_A	0.730	0.78
408_T	412_L	0.729	0.78
60_Q	324_P	0.729	0.78
178_I	361_L	0.727	0.78
420_V	423_A	0.727	0.78
118_I	141_A	0.726	0.78
37_M	40_C	0.725	0.78
201_S	366_D	0.723	0.78
167_L	176_F	0.722	0.78
185_F	368_V	0.722	0.78
214_L	340_L	0.721	0.77
172_T	175_A	0.720	0.77
189_S	369_A	0.720	0.77
267_I	429_I	0.719	0.77
137_M	421_L	0.718	0.77
143_V	372_M	0.718	0.77
233_G	236_T	0.716	0.77
259_T	263_W	0.715	0.77
52_V	56_A	0.715	0.77
162_S	165_T	0.714	0.77
150_L	153_T	0.713	0.77
16_K	307_V	0.711	0.76
90_W	281_S	0.710	0.76
20_I	102_Y	0.710	0.76
104_F	110_K	0.709	0.76
65_N	76_F	0.708	0.76
223_F	227_S	0.708	0.76
272_G	368_V	0.708	0.76
7_G	239_F	0.708	0.76
164_L	357_M	0.706	0.76
9_V	93_Y	0.706	0.76
62_P	65_N	0.706	0.76
3_L	239_F	0.703	0.76
97_S	239_F	0.702	0.76
182_G	398_I	0.702	0.76
152_V	413_E	0.701	0.75
224_I	311_Y	0.700	0.75
78_V	82_F	0.694	0.75
88_S	239_F	0.694	0.75
108_K	443_Q	0.693	0.75
29_Y	193_I	0.692	0.75
111_G	119_A	0.688	0.74
225_T	307_V	0.682	0.73
25_G	28_E	0.681	0.73
397_V	400_L	0.679	0.73
43_L	88_S	0.679	0.73
315_Q	339_V	0.676	0.73
41_A	273_V	0.675	0.73
185_F	373_A	0.673	0.72
28_E	282_R	0.672	0.72
443_Q	446_A	0.669	0.72
97_S	102_Y	0.669	0.72
370_Y	391_R	0.669	0.72
169_D	174_Q	0.668	0.72
50_W	335_A	0.668	0.72
15_S	290_I	0.667	0.72
121_I	436_G	0.666	0.72
373_A	387_D	0.666	0.72
9_V	95_L	0.666	0.72
311_Y	362_A	0.666	0.72
186_C	396_V	0.664	0.71
9_V	294_I	0.662	0.71
89_A	419_V	0.658	0.71
84_H	263_W	0.655	0.70
96_A	270_T	0.654	0.70
288_E	291_W	0.654	0.70
61_T	68_P	0.654	0.70
30_S	36_F	0.654	0.70
346_G	351_A	0.654	0.70
120_A	135_D	0.652	0.70
91_A	294_I	0.652	0.70
197_L	386_P	0.652	0.70
346_G	349_F	0.652	0.70
188_S	204_V	0.650	0.70
272_G	364_H	0.650	0.70
432_V	435_G	0.649	0.70
153_T	156_T	0.649	0.70
115_S	368_V	0.647	0.70
439_R	442_K	0.645	0.69
78_V	227_S	0.644	0.69
340_L	344_P	0.644	0.69
101_A	289_V	0.644	0.69
53_A	56_A	0.644	0.69
254_F	304_F	0.642	0.69
102_Y	107_R	0.642	0.69
60_Q	69_R	0.642	0.69
107_R	150_L	0.640	0.69
324_P	327_L	0.639	0.69
226_N	229_I	0.639	0.69
229_I	244_L	0.638	0.68
132_K	136_L	0.638	0.68
164_L	350_L	0.637	0.68
32_L	295_L	0.637	0.68
158_T	162_S	0.636	0.68
42_G	274_A	0.636	0.68
11_Y	14_T	0.636	0.68
377_T	390_L	0.635	0.68
38_F	42_G	0.634	0.68
189_S	365_M	0.634	0.68
80_Y	264_L	0.633	0.68
383_G	386_P	0.633	0.68
289_V	297_S	0.630	0.67
155_A	174_Q	0.630	0.67
217_I	397_V	0.629	0.67
148_I	419_V	0.627	0.67
34_W	292_G	0.626	0.67
204_V	360_F	0.625	0.67
52_V	312_A	0.619	0.66
212_P	300_G	0.619	0.66
139_L	372_M	0.618	0.66
55_W	402_P	0.616	0.66
88_S	92_T	0.613	0.65
339_V	343_L	0.612	0.65
110_K	127_Q	0.611	0.65
62_P	73_A	0.608	0.65
142_T	263_W	0.607	0.65
202_K	206_W	0.607	0.65
341_M	346_G	0.607	0.65
197_L	367_A	0.605	0.64
44_G	47_T	0.605	0.64
141_A	268_S	0.605	0.64
143_V	398_I	0.604	0.64
216_L	224_I	0.602	0.64
178_I	406_L	0.602	0.64
214_L	344_P	0.598	0.63
35_L	300_G	0.595	0.63
90_W	360_F	0.594	0.63
102_Y	437_F	0.594	0.63
106_V	384_D	0.593	0.63
91_A	95_L	0.592	0.63
95_L	434_V	0.592	0.63
285_K	288_E	0.592	0.63
217_I	225_T	0.591	0.63
43_L	266_W	0.591	0.63
75_E	234_L	0.590	0.62
236_T	239_F	0.589	0.62
215_V	308_M	0.589	0.62
100_M	275_M	0.588	0.62
118_I	131_G	0.588	0.62
54_E	258_W	0.587	0.62
57_Y	332_G	0.586	0.62
247_D	253_S	0.586	0.62
280_V	433_K	0.584	0.62
379_N	384_D	0.583	0.62
312_A	339_V	0.581	0.61
310_S	314_H	0.581	0.61
231_A	249_L	0.580	0.61
133_L	136_L	0.580	0.61
74_L	223_F	0.579	0.61
10_I	294_I	0.579	0.61
25_G	29_Y	0.579	0.61
405_I	412_L	0.577	0.61
86_G	90_W	0.576	0.61
50_W	245_F	0.575	0.60
311_Y	314_H	0.575	0.60
192_G	366_D	0.574	0.60
398_I	419_V	0.573	0.60
267_I	430_L	0.573	0.60
56_A	335_A	0.572	0.60
442_K	445_Y	0.572	0.60
222_E	225_T	0.572	0.60
46_S	266_W	0.569	0.60
36_F	202_K	0.568	0.60
178_I	403_L	0.568	0.60
215_V	315_Q	0.568	0.60
21_R	25_G	0.566	0.59
120_A	131_G	0.565	0.59
159_R	169_D	0.565	0.59
59_Y	74_L	0.564	0.59
319_G	324_P	0.564	0.59
408_T	411_S	0.563	0.59
370_Y	374_A	0.563	0.59
397_V	401_I	0.562	0.59
102_Y	286_I	0.560	0.58
269_Y	273_V	0.560	0.58
441_L	445_Y	0.559	0.58
104_F	437_F	0.558	0.58
154_A	178_I	0.558	0.58
417_T	420_V	0.556	0.58
89_A	93_Y	0.556	0.58
336_V	357_M	0.556	0.58
13_A	16_K	0.556	0.58
186_C	399_T	0.556	0.58
94_T	290_I	0.556	0.58
99_I	267_I	0.555	0.58
442_K	446_A	0.553	0.58
212_P	216_L	0.552	0.57
163_A	346_G	0.551	0.57
35_L	111_G	0.551	0.57
332_G	339_V	0.549	0.57
205_G	359_I	0.549	0.57
121_I	128_G	0.549	0.57
28_E	279_R	0.549	0.57
63_G	68_P	0.548	0.57
279_R	391_R	0.547	0.57
55_W	138_F	0.547	0.57
400_L	404_S	0.547	0.57
221_T	225_T	0.547	0.57
269_Y	272_G	0.547	0.57
22_L	282_R	0.546	0.57
120_A	128_G	0.546	0.57
249_L	411_S	0.546	0.57
373_A	376_S	0.546	0.57
224_I	310_S	0.545	0.56
180_L	183_G	0.544	0.56
261_F	264_L	0.544	0.56
114_L	138_F	0.543	0.56
165_T	351_A	0.543	0.56
428_V	431_L	0.543	0.56
38_F	277_V	0.543	0.56
124_V	128_G	0.543	0.56
43_L	262_Y	0.543	0.56
12_L	441_L	0.543	0.56
384_D	389_G	0.542	0.56
99_I	104_F	0.541	0.56
50_W	254_F	0.540	0.56
191_I	365_M	0.540	0.56
181_S	184_I	0.540	0.56
172_T	348_L	0.538	0.55
107_R	282_R	0.538	0.55
247_D	250_G	0.538	0.55
54_E	85_W	0.536	0.55
233_G	248_P	0.536	0.55
179_L	351_A	0.535	0.55
193_I	388_R	0.534	0.55
157_F	358_I	0.533	0.55
424_L	427_L	0.533	0.55
298_T	301_C	0.532	0.55
51_G	436_G	0.532	0.55
92_T	430_L	0.531	0.55
441_L	444_D	0.531	0.55
45_S	51_G	0.530	0.54
89_A	301_C	0.530	0.54
133_L	443_Q	0.529	0.54
311_Y	315_Q	0.528	0.54
38_F	367_A	0.528	0.54
185_F	398_I	0.528	0.54
114_L	426_F	0.527	0.54
185_F	189_S	0.527	0.54
164_L	277_V	0.525	0.54
327_L	330_L	0.525	0.54
323_V	339_V	0.524	0.54
336_V	340_L	0.522	0.53
434_V	438_I	0.522	0.53
11_Y	19_N	0.520	0.53
120_A	439_R	0.520	0.53
6_M	294_I	0.519	0.53
48_L	419_V	0.519	0.53
47_T	208_A	0.519	0.53
157_F	181_S	0.519	0.53
320_V	323_V	0.518	0.53
149_S	305_F	0.518	0.53
270_T	373_A	0.518	0.53
413_E	421_L	0.517	0.53
143_V	365_M	0.516	0.52
303_F	307_V	0.515	0.52
50_W	258_W	0.515	0.52
413_E	417_T	0.515	0.52
211_L	353_Y	0.514	0.52
4_L	69_R	0.514	0.52
331_G	338_Q	0.513	0.52
51_G	441_L	0.513	0.52
216_L	354_L	0.512	0.52
141_A	395_C	0.512	0.52
148_I	152_V	0.512	0.52
261_F	268_S	0.512	0.52
246_T	255_T	0.509	0.51
443_Q	447_D	0.508	0.51
12_L	17_Y	0.508	0.51
6_M	48_L	0.507	0.51
7_G	240_L	0.507	0.51
87_I	232_I	0.507	0.51
315_Q	320_V	0.506	0.51
264_L	424_L	0.506	0.51
76_F	79_P	0.504	0.51
275_M	374_A	0.504	0.51
232_I	288_E	0.503	0.51
195_N	198_Q	0.503	0.51
144_G	371_T	0.502	0.51
244_L	247_D	0.501	0.50
22_L	102_Y	0.500	0.50

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4c7rA	3	0.9751	100	0.066	Contact Map
2wswA	3	0.9231	100	0.069	Contact Map
2xq2A	2	0.8773	97.7	0.949	Contact Map
3dh4A	3	0.8337	97.4	0.953	Contact Map
3giaA	1	0.763	95.7	0.961	Contact Map
3l1lA	2	0.7734	94.2	0.964	Contact Map
4djkA	2	0.7214	88.9	0.969	Contact Map
2jlnA	1	0.738	74.3	0.974	Contact Map
4us3A	1	0.7173	59.5	0.976	Contact Map
4h33A	3	0.1705	37.1	0.979	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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