BETT - ECOLI - GREMLIN Contacts

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BETT - High-affinity choline transport protein

UniProt:	P0ABC9	Sequences: MTDLSHSREKDKINPVVFYTSAGLILLFSLTTILFRDFSALWIGRTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSVKLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMALGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPDSMAAKAALIALSVIIATISVTSGVDKGIRVLSELNVALALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPVEWMNNWTLFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALYEIIHGGAAFAEEAMVHPERGFYSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSQLKDINSDAPGWLRVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFSFVIFFVMAGLYKSLKVEDYRRESANRDTAPRPLGLQDRLSWKKRLSRLMNYPGTRYTKQMMETVCYPAMEEVAQELRLRGAYVELKSLPPEEGQQLGHLDLLVHMGEEQNFVYQIWPQQYSVPGFTYRARSGKSTYYRLETFLLEGSQGNDLMDYSKEQVITDILDQYERHLNFIHLHREAPGHSVMFPDA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10112
Length:	677 (524)
Sequences:	1293 (817)
Seq/√Len:	35.7

ECOLI - BETT CAIT YEAV
BACSU - OPUD
HALSA - Q9HQN5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
81_K	88_K	5.707	1.00
199_V	436_T	5.399	1.00
20_T	196_I	4.897	1.00
30_L	34_L	4.692	1.00
57_Y	486_S	4.587	1.00
274_F	409_S	4.516	1.00
425_A	458_I	3.735	1.00
232_A	236_A	3.679	1.00
131_T	134_A	3.558	1.00
189_P	193_S	3.458	1.00
68_F	493_M	3.385	1.00
22_A	453_F	3.377	1.00
178_L	194_V	3.362	1.00
275_V	403_Y	3.281	1.00
425_A	429_A	3.212	1.00
87_S	343_R	3.173	1.00
118_V	377_I	3.171	1.00
70_V	74_C	3.134	1.00
62_A	153_M	2.905	1.00
91_F	254_D	2.900	1.00
347_I	500_L	2.869	1.00
274_F	278_M	2.813	1.00
84_P	87_S	2.809	1.00
121_Y	378_I	2.700	1.00
377_I	383_A	2.696	1.00
375_Y	379_H	2.617	1.00
247_I	251_S	2.607	1.00
429_A	458_I	2.424	1.00
250_T	452_V	2.362	1.00
398_S	401_A	2.361	1.00
212_I	322_F	2.357	1.00
16_V	192_H	2.342	0.99
487_F	491_F	2.335	0.99
251_S	259_V	2.317	0.99
268_A	420_F	2.310	0.99
175_R	192_H	2.269	0.99
408_F	411_S	2.268	0.99
405_A	408_F	2.236	0.99
218_N	234_K	2.228	0.99
236_A	240_L	2.195	0.99
143_L	363_L	2.165	0.99
383_A	386_E	2.145	0.99
76_R	79_S	2.137	0.99
403_Y	408_F	2.134	0.99
214_V	237_L	2.106	0.99
259_V	263_L	2.097	0.99
276_L	368_V	2.070	0.99
122_M	385_A	2.047	0.99
35_F	38_F	2.035	0.99
31_T	39_S	2.034	0.99
121_Y	130_Q	2.027	0.98
246_T	250_T	2.005	0.98
49_W	54_F	1.998	0.98
372_S	403_Y	1.990	0.98
246_T	455_S	1.982	0.98
189_P	192_H	1.980	0.98
33_I	464_G	1.967	0.98
29_S	461_L	1.953	0.98
154_Y	327_W	1.952	0.98
61_A	486_S	1.946	0.98
288_L	364_L	1.937	0.98
160_A	492_V	1.936	0.98
276_L	285_L	1.936	0.98
227_I	233_A	1.896	0.98
246_T	452_V	1.874	0.97
364_L	368_V	1.872	0.97
376_E	402_Q	1.872	0.97
433_G	450_L	1.870	0.97
71_C	497_Y	1.860	0.97
19_Y	23_G	1.850	0.97
68_F	497_Y	1.843	0.97
25_I	203_I	1.843	0.97
218_N	233_A	1.827	0.97
243_I	247_I	1.823	0.97
456_V	460_L	1.810	0.97
46_T	49_W	1.809	0.97
65_Y	489_I	1.809	0.97
98_A	102_A	1.789	0.97
239_A	463_L	1.777	0.96
182_F	186_I	1.774	0.96
423_T	427_S	1.763	0.96
429_A	455_S	1.756	0.96
235_A	463_L	1.748	0.96
233_A	236_A	1.745	0.96
197_A	481_M	1.730	0.96
178_L	201_G	1.727	0.96
170_L	186_I	1.727	0.96
322_F	329_A	1.721	0.96
367_S	372_S	1.701	0.95
31_T	38_F	1.696	0.95
416_T	419_L	1.692	0.95
61_A	490_F	1.682	0.95
112_F	489_I	1.671	0.95
329_A	478_T	1.647	0.95
150_G	327_W	1.644	0.95
206_I	257_I	1.636	0.94
65_Y	493_M	1.636	0.94
50_V	483_L	1.625	0.94
73_A	352_L	1.624	0.94
64_L	490_F	1.621	0.94
170_L	179_Y	1.617	0.94
28_F	204_F	1.617	0.94
84_P	167_R	1.616	0.94
44_G	48_D	1.588	0.93
128_A	131_T	1.577	0.93
273_L	277_F	1.575	0.93
231_M	467_M	1.562	0.93
95_S	98_A	1.551	0.93
105_I	108_D	1.547	0.93
95_S	262_E	1.544	0.92
156_L	489_I	1.539	0.92
432_L	458_I	1.538	0.92
67_V	71_C	1.533	0.92
222_S	229_D	1.527	0.92
288_L	363_L	1.527	0.92
218_N	229_D	1.514	0.92
15_P	19_Y	1.513	0.92
159_M	347_I	1.510	0.92
298_R	301_G	1.502	0.91
272_I	368_V	1.501	0.91
164_F	499_S	1.476	0.91
355_L	483_L	1.455	0.90
242_V	459_G	1.451	0.90
221_L	225_F	1.448	0.90
57_Y	487_F	1.443	0.90
46_T	480_I	1.442	0.90
177_A	492_V	1.440	0.90
92_S	95_S	1.431	0.89
288_L	367_S	1.430	0.89
331_S	489_I	1.419	0.89
249_V	425_A	1.407	0.88
263_L	419_L	1.397	0.88
124_P	127_G	1.397	0.88
181_I	190_I	1.388	0.88
147_G	359_F	1.377	0.87
217_L	414_T	1.374	0.87
148_L	355_L	1.372	0.87
298_R	302_M	1.364	0.87
39_S	43_I	1.334	0.86
265_V	488_V	1.334	0.86
124_P	134_A	1.319	0.85
291_N	367_S	1.317	0.85
386_E	390_V	1.304	0.84
130_Q	134_A	1.298	0.84
26_L	247_I	1.295	0.84
175_R	245_A	1.295	0.84
84_P	169_N	1.294	0.84
75_S	78_G	1.290	0.84
270_G	408_F	1.287	0.83
173_T	439_L	1.283	0.83
105_I	150_G	1.280	0.83
248_S	426_D	1.271	0.83
451_R	455_S	1.269	0.83
64_L	493_M	1.265	0.82
283_F	378_I	1.257	0.82
164_F	170_L	1.257	0.82
209_T	213_G	1.256	0.82
527_W	531_L	1.252	0.82
127_G	137_Q	1.248	0.81
263_L	266_A	1.248	0.81
49_W	53_T	1.248	0.81
107_I	213_G	1.233	0.81
201_G	451_R	1.231	0.81
314_E	318_N	1.231	0.81
238_I	462_T	1.222	0.80
14_N	192_H	1.220	0.80
32_T	464_G	1.218	0.80
297_N	301_G	1.218	0.80
74_C	352_L	1.217	0.80
87_S	167_R	1.216	0.80
18_F	125_P	1.216	0.80
129_G	134_A	1.216	0.80
184_K	187_N	1.205	0.79
42_W	45_R	1.205	0.79
500_L	503_E	1.199	0.79
528_K	531_L	1.184	0.78
40_A	230_S	1.182	0.78
230_S	233_A	1.181	0.78
149_T	295_Y	1.168	0.77
406_F	410_A	1.166	0.77
206_I	428_G	1.164	0.77
66_I	70_V	1.161	0.76
29_S	464_G	1.161	0.76
71_C	79_S	1.160	0.76
287_A	371_N	1.157	0.76
63_T	149_T	1.156	0.76
188_G	191_G	1.152	0.76
300_M	303_T	1.151	0.76
105_I	362_T	1.147	0.76
380_G	402_Q	1.145	0.75
37_D	40_A	1.145	0.75
227_I	277_F	1.144	0.75
230_S	235_A	1.144	0.75
168_Y	355_L	1.140	0.75
420_F	474_L	1.137	0.75
130_Q	378_I	1.132	0.75
485_F	488_V	1.131	0.75
529_K	536_N	1.122	0.74
268_A	396_F	1.121	0.74
38_F	42_W	1.119	0.74
394_R	398_S	1.118	0.74
154_Y	210_L	1.117	0.74
150_G	284_L	1.112	0.73
175_R	428_G	1.108	0.73
244_I	422_V	1.100	0.72
274_F	400_L	1.099	0.72
245_A	455_S	1.099	0.72
235_A	351_V	1.097	0.72
161_L	170_L	1.096	0.72
372_S	399_L	1.094	0.72
65_Y	416_T	1.093	0.72
284_L	371_N	1.092	0.72
95_S	258_R	1.084	0.71
21_S	199_V	1.082	0.71
330_W	424_S	1.082	0.71
280_D	375_Y	1.080	0.71
53_T	282_S	1.079	0.71
111_F	503_E	1.076	0.71
84_P	343_R	1.075	0.71
245_A	433_G	1.070	0.70
520_G	523_D	1.070	0.70
69_V	156_L	1.068	0.70
434_N	446_A	1.063	0.70
72_I	159_M	1.062	0.70
179_Y	187_N	1.057	0.69
251_S	255_K	1.048	0.69
377_I	382_A	1.044	0.68
218_N	228_P	1.043	0.68
34_L	412_V	1.032	0.68
243_I	270_G	1.029	0.67
203_I	363_L	1.028	0.67
356_I	360_T	1.026	0.67
107_I	421_Y	1.025	0.67
325_A	480_I	1.023	0.67
46_T	50_V	1.019	0.67
68_F	156_L	1.018	0.66
16_V	19_Y	1.017	0.66
418_L	422_V	1.016	0.66
81_K	86_Q	1.015	0.66
108_D	327_W	1.015	0.66
482_G	486_S	1.012	0.66
103_A	334_V	1.009	0.66
326_W	475_Q	1.006	0.66
85_E	167_R	1.005	0.65
140_V	302_M	1.005	0.65
24_L	200_I	1.004	0.65
216_Q	248_S	1.003	0.65
153_M	489_I	0.999	0.65
172_L	175_R	0.998	0.65
276_L	281_T	0.996	0.65
63_T	303_T	0.991	0.64
128_A	134_A	0.990	0.64
77_F	501_K	0.985	0.64
25_I	204_F	0.985	0.64
324_W	327_W	0.984	0.64
208_T	474_L	0.978	0.63
25_I	273_L	0.975	0.63
109_L	209_T	0.974	0.63
74_C	236_A	0.974	0.63
32_T	173_T	0.972	0.63
123_Q	129_G	0.971	0.63
227_I	236_A	0.971	0.63
490_F	494_A	0.962	0.62
322_F	328_V	0.961	0.62
273_L	487_F	0.960	0.62
170_L	176_S	0.960	0.62
190_I	193_S	0.960	0.62
112_F	212_I	0.959	0.62
150_G	367_S	0.957	0.62
182_F	495_G	0.955	0.61
483_L	487_F	0.951	0.61
91_F	95_S	0.948	0.61
72_I	347_I	0.948	0.61
525_L	529_K	0.947	0.61
94_L	265_V	0.947	0.61
78_G	348_R	0.946	0.61
80_V	500_L	0.943	0.60
105_I	323_F	0.942	0.60
249_V	253_V	0.942	0.60
87_S	91_F	0.940	0.60
224_L	414_T	0.939	0.60
118_V	384_F	0.935	0.60
82_L	167_R	0.934	0.60
424_S	427_S	0.930	0.59
133_E	137_Q	0.930	0.59
476_N	479_V	0.926	0.59
433_G	446_A	0.925	0.59
166_Y	503_E	0.924	0.59
66_I	299_F	0.924	0.59
185_R	188_G	0.919	0.58
63_T	304_L	0.918	0.58
249_V	455_S	0.915	0.58
272_I	321_L	0.909	0.58
61_A	65_Y	0.903	0.57
140_V	294_D	0.902	0.57
106_G	471_I	0.901	0.57
70_V	227_I	0.900	0.57
66_I	148_L	0.899	0.57
120_Q	315_W	0.899	0.57
376_E	381_G	0.899	0.57
398_S	402_Q	0.897	0.57
122_M	130_Q	0.894	0.56
453_F	457_A	0.892	0.56
433_G	455_S	0.888	0.56
108_D	150_G	0.887	0.56
105_I	482_G	0.887	0.56
201_G	455_S	0.885	0.56
269_L	361_F	0.884	0.55
182_F	190_I	0.882	0.55
207_A	420_F	0.881	0.55
100_L	164_F	0.880	0.55
91_F	401_A	0.876	0.55
91_F	258_R	0.876	0.55
23_G	407_T	0.875	0.55
135_A	378_I	0.873	0.55
93_L	349_Q	0.872	0.54
67_V	273_L	0.871	0.54
270_G	277_F	0.870	0.54
46_T	408_F	0.870	0.54
323_F	327_W	0.868	0.54
403_Y	406_F	0.867	0.54
40_A	44_G	0.866	0.54
283_F	287_A	0.865	0.54
37_D	41_L	0.863	0.54
149_T	299_F	0.863	0.54
126_E	371_N	0.862	0.54
218_N	237_L	0.861	0.53
273_L	401_A	0.861	0.53
350_F	358_P	0.861	0.53
66_I	152_S	0.860	0.53
113_S	397_Y	0.860	0.53
113_S	366_L	0.859	0.53
66_I	156_L	0.857	0.53
59_L	316_M	0.857	0.53
157_M	485_F	0.857	0.53
77_F	497_Y	0.855	0.53
156_L	493_M	0.855	0.53
245_A	428_G	0.853	0.53
331_S	336_L	0.852	0.53
532_S	536_N	0.852	0.53
245_A	249_V	0.851	0.53
231_M	234_K	0.844	0.52
315_W	365_W	0.843	0.52
465_M	477_T	0.843	0.52
111_F	393_E	0.843	0.52
176_S	179_Y	0.842	0.52
202_T	333_F	0.838	0.51
23_G	491_F	0.836	0.51
197_A	488_V	0.835	0.51
130_Q	292_V	0.834	0.51
16_V	20_T	0.832	0.51
105_I	327_W	0.826	0.50
239_A	456_V	0.826	0.50
222_S	225_F	0.825	0.50
262_E	428_G	0.823	0.50
163_Y	489_I	0.823	0.50
41_L	368_V	0.822	0.50
73_A	351_V	0.822	0.50
222_S	228_P	0.822	0.50
110_M	478_T	0.820	0.50
440_K	444_S	0.819	0.50
144_F	316_M	0.815	0.49
105_I	109_L	0.814	0.49
148_L	152_S	0.813	0.49
157_M	253_V	0.811	0.49
152_S	156_L	0.804	0.49
212_I	476_N	0.803	0.48
99_M	341_I	0.801	0.48
294_D	488_V	0.799	0.48
286_N	325_A	0.799	0.48
346_T	412_V	0.798	0.48
171_P	179_Y	0.793	0.48
335_G	339_A	0.792	0.48
264_N	427_S	0.791	0.47
163_Y	503_E	0.790	0.47
151_W	326_W	0.790	0.47
162_G	168_Y	0.789	0.47
125_P	134_A	0.788	0.47
331_S	406_F	0.787	0.47
25_I	455_S	0.787	0.47
65_Y	328_V	0.786	0.47
448_G	452_V	0.784	0.47
221_L	227_I	0.783	0.47
156_L	464_G	0.781	0.47
164_F	403_Y	0.780	0.46
472_S	475_Q	0.773	0.46
403_Y	409_S	0.772	0.46
338_L	354_T	0.771	0.46
50_V	480_I	0.771	0.46
527_W	530_R	0.770	0.46
160_A	328_V	0.768	0.45
132_I	378_I	0.768	0.45
259_V	529_K	0.768	0.45
241_S	425_A	0.766	0.45
112_F	392_P	0.765	0.45
303_T	306_S	0.765	0.45
529_K	535_M	0.764	0.45
532_S	535_M	0.764	0.45
179_Y	186_I	0.764	0.45
64_L	156_L	0.763	0.45
324_W	340_R	0.763	0.45
166_Y	255_K	0.763	0.45
201_G	429_A	0.763	0.45
406_F	413_A	0.762	0.45
115_A	315_W	0.757	0.44
249_V	290_L	0.757	0.44
425_A	455_S	0.756	0.44
433_G	447_P	0.753	0.44
405_A	409_S	0.753	0.44
63_T	299_F	0.752	0.44
330_W	333_F	0.751	0.44
105_I	149_T	0.751	0.44
203_I	432_L	0.751	0.44
221_L	233_A	0.749	0.44
54_F	155_A	0.748	0.44
102_A	341_I	0.747	0.44
305_N	316_M	0.745	0.43
43_I	249_V	0.745	0.43
107_I	127_G	0.745	0.43
65_Y	156_L	0.744	0.43
447_P	450_L	0.742	0.43
224_L	460_L	0.739	0.43
40_A	347_I	0.738	0.43
413_A	427_S	0.736	0.43
249_V	438_Q	0.735	0.43
21_S	136_R	0.734	0.43
102_A	419_L	0.734	0.43
114_V	395_G	0.732	0.42
59_L	63_T	0.731	0.42
250_T	448_G	0.730	0.42
331_S	436_T	0.728	0.42
73_A	156_L	0.725	0.42
203_I	458_I	0.724	0.42
396_F	413_A	0.724	0.42
198_A	207_A	0.722	0.42
20_T	23_G	0.721	0.41
31_T	35_F	0.721	0.41
121_Y	277_F	0.719	0.41
63_T	238_I	0.718	0.41
177_A	183_G	0.718	0.41
91_F	340_R	0.718	0.41
158_G	224_L	0.717	0.41
244_I	247_I	0.715	0.41
141_W	307_F	0.713	0.41
240_L	244_I	0.711	0.41
385_A	389_M	0.710	0.41
108_D	146_Y	0.709	0.40
154_Y	329_A	0.709	0.40
18_F	55_G	0.707	0.40
308_A	430_L	0.707	0.40
284_L	416_T	0.702	0.40
123_Q	128_A	0.701	0.40
268_A	424_S	0.700	0.40
147_G	150_G	0.699	0.40
242_V	480_I	0.699	0.40
206_I	217_L	0.699	0.40
400_L	403_Y	0.699	0.40
18_F	453_F	0.698	0.40
116_E	319_W	0.697	0.39
356_I	374_L	0.696	0.39
157_M	160_A	0.696	0.39
101_F	151_W	0.695	0.39
158_G	299_F	0.695	0.39
432_L	461_L	0.693	0.39
273_L	498_K	0.692	0.39
360_T	364_L	0.691	0.39
140_V	298_R	0.690	0.39
103_A	333_F	0.689	0.39
210_L	248_S	0.689	0.39
242_V	458_I	0.688	0.39
124_P	129_G	0.687	0.39
235_A	467_M	0.686	0.39
306_S	316_M	0.685	0.38
249_V	325_A	0.685	0.38
163_Y	167_R	0.685	0.38
479_V	482_G	0.683	0.38
388_A	391_H	0.683	0.38
158_G	459_G	0.682	0.38
268_A	413_A	0.682	0.38
531_L	535_M	0.682	0.38
411_S	415_I	0.682	0.38
214_V	218_N	0.682	0.38
102_A	110_M	0.681	0.38
54_F	298_R	0.681	0.38
285_L	368_V	0.681	0.38
193_S	368_V	0.681	0.38
46_T	529_K	0.680	0.38
519_L	522_Q	0.680	0.38
272_I	332_P	0.680	0.38
245_A	451_R	0.679	0.38
425_A	432_L	0.678	0.38
161_L	477_T	0.677	0.38
27_L	31_T	0.677	0.38
166_Y	274_F	0.676	0.38
126_E	137_Q	0.676	0.38
340_R	445_D	0.676	0.38
28_F	160_A	0.675	0.38
136_R	290_L	0.674	0.38
290_L	309_F	0.673	0.37
112_F	271_L	0.671	0.37
160_A	177_A	0.669	0.37
27_L	408_F	0.668	0.37
371_N	375_Y	0.668	0.37
34_L	193_S	0.668	0.37
272_I	361_F	0.667	0.37
343_R	348_R	0.667	0.37
526_S	529_K	0.665	0.37
251_S	360_T	0.664	0.37
72_I	77_F	0.662	0.37
97_A	357_I	0.661	0.36
242_V	421_Y	0.661	0.36
46_T	74_C	0.660	0.36
107_I	329_A	0.660	0.36
71_C	75_S	0.660	0.36
523_D	531_L	0.658	0.36
24_L	72_I	0.658	0.36
377_I	435_F	0.658	0.36
432_L	438_Q	0.658	0.36
396_F	482_G	0.658	0.36
529_K	532_S	0.655	0.36
415_I	529_K	0.654	0.36
113_S	500_L	0.654	0.36
181_I	247_I	0.654	0.36
330_W	358_P	0.653	0.36
377_I	479_V	0.653	0.36
64_L	130_Q	0.651	0.36
400_L	409_S	0.649	0.36
112_F	470_G	0.649	0.36
64_L	72_I	0.649	0.36
150_G	200_I	0.648	0.35
166_Y	409_S	0.648	0.35
68_F	417_G	0.646	0.35
32_T	473_A	0.645	0.35
341_I	522_Q	0.645	0.35
266_A	270_G	0.644	0.35
141_W	316_M	0.643	0.35
290_L	308_A	0.643	0.35
458_I	462_T	0.642	0.35
250_T	298_R	0.642	0.35
48_D	52_K	0.642	0.35
51_S	91_F	0.641	0.35
276_L	284_L	0.640	0.35
165_S	169_N	0.639	0.35
110_M	413_A	0.639	0.35
243_I	532_S	0.639	0.35
216_Q	295_Y	0.639	0.35
223_V	226_D	0.639	0.35
472_S	487_F	0.636	0.35
250_T	253_V	0.635	0.34
283_F	414_T	0.633	0.34
56_W	358_P	0.633	0.34
98_A	321_L	0.631	0.34
40_A	70_V	0.631	0.34
131_T	226_D	0.631	0.34
163_Y	499_S	0.631	0.34
336_L	434_N	0.627	0.34
331_S	481_M	0.627	0.34
59_L	110_M	0.626	0.34
397_Y	435_F	0.626	0.34
67_V	299_F	0.626	0.34
465_M	471_I	0.625	0.34
531_L	534_L	0.625	0.34
322_F	477_T	0.624	0.34
47_L	476_N	0.624	0.34
141_W	315_W	0.624	0.34
430_L	466_L	0.623	0.34
464_G	524_R	0.622	0.33
271_L	409_S	0.621	0.33
29_S	162_G	0.618	0.33
109_L	367_S	0.615	0.33
472_S	532_S	0.615	0.33
223_V	227_I	0.614	0.33
135_A	283_F	0.610	0.33
41_L	270_G	0.609	0.32
177_A	185_R	0.609	0.32
21_S	436_T	0.608	0.32
377_I	381_G	0.606	0.32
134_A	225_F	0.606	0.32
276_L	364_L	0.605	0.32
84_P	201_G	0.604	0.32
354_T	397_Y	0.604	0.32
405_A	411_S	0.603	0.32
239_A	296_V	0.602	0.32
59_L	317_N	0.601	0.32
85_E	199_V	0.601	0.32
435_F	458_I	0.599	0.32
208_T	465_M	0.598	0.32
161_L	164_F	0.596	0.31
69_V	355_L	0.596	0.31
62_A	149_T	0.596	0.31
311_R	314_E	0.595	0.31
81_K	453_F	0.595	0.31
105_I	176_S	0.594	0.31
110_M	362_T	0.593	0.31
14_N	160_A	0.593	0.31
33_I	52_K	0.592	0.31
109_L	213_G	0.591	0.31
112_F	115_A	0.589	0.31
25_I	67_V	0.588	0.31
241_S	249_V	0.588	0.31
152_S	317_N	0.588	0.31
174_I	416_T	0.587	0.31
240_L	243_I	0.586	0.31
91_F	434_N	0.585	0.31
91_F	99_M	0.585	0.31
258_R	262_E	0.584	0.31
18_F	22_A	0.584	0.31
231_M	235_A	0.583	0.30
437_S	450_L	0.583	0.30
100_L	106_G	0.583	0.30
196_I	475_Q	0.581	0.30
52_K	472_S	0.581	0.30
274_F	405_A	0.580	0.30
21_S	385_A	0.580	0.30
331_S	437_S	0.580	0.30
333_F	431_V	0.579	0.30
39_S	461_L	0.578	0.30
28_F	453_F	0.576	0.30
98_A	408_F	0.576	0.30
277_F	379_H	0.576	0.30
330_W	397_Y	0.575	0.30
340_R	349_Q	0.575	0.30
151_W	420_F	0.575	0.30
224_L	418_L	0.574	0.30
166_Y	415_I	0.574	0.30
336_L	432_L	0.573	0.30
294_D	298_R	0.572	0.30
57_Y	490_F	0.571	0.30
523_D	528_K	0.571	0.30
165_S	172_L	0.570	0.30
299_F	317_N	0.570	0.30
145_H	191_G	0.569	0.29
32_T	39_S	0.566	0.29
71_C	102_A	0.565	0.29
57_Y	318_N	0.564	0.29
105_I	142_T	0.564	0.29
257_I	262_E	0.563	0.29
210_L	327_W	0.562	0.29
207_A	474_L	0.561	0.29
61_A	193_S	0.561	0.29
151_W	342_S	0.560	0.29
341_I	368_V	0.560	0.29
172_L	208_T	0.560	0.29
429_A	451_R	0.559	0.29
74_C	232_A	0.559	0.29
110_M	446_A	0.558	0.29
15_P	20_T	0.558	0.29
166_Y	504_D	0.558	0.29
68_F	72_I	0.558	0.29
330_W	334_V	0.558	0.29
273_L	325_A	0.558	0.29
277_F	508_E	0.558	0.29
417_G	423_T	0.558	0.29
243_I	498_K	0.557	0.29
257_I	452_V	0.557	0.29
440_K	446_A	0.557	0.29
530_R	533_R	0.557	0.29
183_G	268_A	0.557	0.29
139_M	216_Q	0.556	0.29
95_S	251_S	0.555	0.28
26_L	181_I	0.555	0.28
528_K	532_S	0.553	0.28
156_L	400_L	0.552	0.28
419_L	514_T	0.552	0.28
414_T	418_L	0.551	0.28
523_D	527_W	0.550	0.28
158_G	178_L	0.550	0.28
390_V	472_S	0.550	0.28
212_I	329_A	0.550	0.28
220_G	397_Y	0.550	0.28
189_P	343_R	0.549	0.28
152_S	210_L	0.549	0.28
27_L	54_F	0.549	0.28
112_F	209_T	0.548	0.28
257_I	386_E	0.547	0.28
217_L	306_S	0.547	0.28
255_K	259_V	0.547	0.28
85_E	482_G	0.547	0.28
108_D	417_G	0.547	0.28
381_G	402_Q	0.546	0.28
150_G	154_Y	0.546	0.28
172_L	451_R	0.545	0.28
95_S	99_M	0.545	0.28
226_D	247_I	0.544	0.28
196_I	415_I	0.544	0.28
420_F	424_S	0.544	0.28
336_L	416_T	0.544	0.28
53_T	166_Y	0.543	0.28
491_F	494_A	0.543	0.28
248_S	474_L	0.543	0.28
198_A	216_Q	0.543	0.28
87_S	163_Y	0.542	0.28
288_L	360_T	0.542	0.28
273_L	456_V	0.542	0.28
429_A	435_F	0.541	0.27
213_G	327_W	0.540	0.27
81_K	520_G	0.540	0.27
351_V	486_S	0.540	0.27
413_A	423_T	0.539	0.27
408_F	412_V	0.538	0.27
440_K	488_V	0.537	0.27
106_G	334_V	0.537	0.27
58_Y	482_G	0.536	0.27
526_S	533_R	0.536	0.27
42_W	490_F	0.536	0.27
134_A	226_D	0.536	0.27
295_Y	330_W	0.536	0.27
105_I	213_G	0.533	0.27
498_K	502_V	0.533	0.27
293_G	304_L	0.533	0.27
71_C	74_C	0.533	0.27
513_D	522_Q	0.532	0.27
27_L	53_T	0.532	0.27
117_P	431_V	0.532	0.27
331_S	433_G	0.532	0.27
428_G	451_R	0.531	0.27
59_L	306_S	0.530	0.27
304_L	421_Y	0.529	0.27
411_S	414_T	0.528	0.27
116_E	475_Q	0.527	0.27
30_L	273_L	0.527	0.27
27_L	34_L	0.527	0.27
213_G	334_V	0.526	0.26
155_A	213_G	0.526	0.26
76_R	284_L	0.523	0.26
163_Y	217_L	0.523	0.26
99_M	102_A	0.523	0.26
414_T	439_L	0.523	0.26
81_K	223_V	0.522	0.26
109_L	361_F	0.522	0.26
47_L	323_F	0.521	0.26
382_A	385_A	0.521	0.26
236_A	314_E	0.521	0.26
107_I	332_P	0.521	0.26
136_R	406_F	0.520	0.26
384_F	388_A	0.519	0.26
227_I	270_G	0.519	0.26
26_L	45_R	0.518	0.26
188_G	473_A	0.518	0.26
376_E	403_Y	0.518	0.26
204_F	330_W	0.518	0.26
63_T	306_S	0.518	0.26
137_Q	141_W	0.518	0.26
185_R	476_N	0.517	0.26
23_G	26_L	0.517	0.26
234_K	466_L	0.517	0.26
128_A	325_A	0.517	0.26
246_T	459_G	0.516	0.26
278_M	403_Y	0.516	0.26
151_W	354_T	0.516	0.26
306_S	478_T	0.516	0.26
129_G	226_D	0.515	0.26
65_Y	354_T	0.515	0.26
76_R	94_L	0.515	0.26
124_P	453_F	0.514	0.26
213_G	358_P	0.514	0.26
21_S	156_L	0.513	0.26
215_V	425_A	0.512	0.26
511_N	515_A	0.512	0.26
92_S	259_V	0.512	0.26
184_K	343_R	0.511	0.25
149_T	202_T	0.511	0.25
272_I	353_G	0.511	0.25
240_L	415_I	0.511	0.25
498_K	501_K	0.510	0.25
95_S	108_D	0.509	0.25
340_R	451_R	0.508	0.25
341_I	492_V	0.508	0.25
96_W	353_G	0.508	0.25
118_V	218_N	0.507	0.25
375_Y	467_M	0.507	0.25
259_V	262_E	0.506	0.25
52_K	467_M	0.505	0.25
34_L	456_V	0.505	0.25
478_T	503_E	0.504	0.25
374_L	378_I	0.504	0.25
190_I	194_V	0.504	0.25
125_P	459_G	0.503	0.25
163_Y	348_R	0.503	0.25
26_L	412_V	0.503	0.25
162_G	300_M	0.503	0.25
58_Y	177_A	0.502	0.25
101_F	324_W	0.501	0.25
413_A	424_S	0.500	0.25
170_L	245_A	0.500	0.25
77_F	80_V	0.500	0.25

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4c7rA	3	0.774	100	0.264	Contact Map
2wswA	3	0.7415	100	0.281	Contact Map
2xq2A	2	0.6677	96.6	0.972	Contact Map
3dh4A	3	0.6292	94.9	0.976	Contact Map
3giaA	1	0.5879	89.6	0.98	Contact Map
4djkA	2	0.551	89	0.98	Contact Map
3l1lA	2	0.5805	86.8	0.981	Contact Map
2jlnA	1	0.6307	63	0.984	Contact Map
4pypA	1	0.517	58.7	0.985	Contact Map
3wdoA	1	0.5968	47.9	0.986	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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