ATMA - ECOLI - GREMLIN Contacts

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ATMA - Magnesium-transporting ATPase, P-type 1

UniProt:	P0ABB8	Sequences: MFKEIFTRLIRHLPSRLVHRDPLPGAQQTVNTVVPPSLSAHCLKMAVMPEEELWKTFDTHPEGLNQAEVESAREQHGENKLPAQQPSPWWVHLWVCYRNPFNILLTILGAISYATEDLFAAGVIALMVAISTLLNFIQEARSTKAADALKAMVSNTATVLRVINDKGENGWLEIPIDQLVPGDIIKLAAGDMIPADLRILQARDLFVAQASLTGESLPVEKAATTRQPEHSNPLECDTLCFMGTTVVSGTAQAMVIATGANTWFGQLAGRVSEQESEPNAFQQGISRVSMLLIRFMLVMAPVVLLINGYTKGDWWEAALFALSVAVGLTPEMLPMIVTSTLARGAVKLSKQKVIVKHLDAIQNFGAMDILCTDKTGTLTQDKIVLENHTDISGKTSERVLHSAWLNSHYQTGLKNLLDTAVLEGTDEESARSLASRWQKIDEIPFDFERRRMSVVVAENTEHHQLVCKGALQEILNVCSQVRHNGEIVPLDDIMLRKIKRVTDTLNRQGLRVVAVATKYLPAREGDYQRADESDLILEGYIAFLDPPKETTAPALKALKASGITVKILTGDSELVAAKVCHEVGLDAGEVVIGSDIETLSDDELANLAQRTTLFARLTPMHKERIVTLLKREGHVVGFMGDGINDAPALRAADIGISVDGAVDIAREAADIILLEKSLMVLEEGVIEGRRTFANMLKYIKMTASSNFGNVFSVLVASAFLPFLPMLPLHLLIQNLLYDVSQVAIPFDNVDDEQIQKPQRWNPADLGRFMIFFGPISSIFDILTFCLMWWVFHANTPETQTLFQSGWFVVGLLSQTLIVHMIRTRRVPFIQSCASWPLMIMTVIVMIVGIALPFSPLASYLQLQALPLSYFPWLVAILAGYMTLTQLVKGFYSRRYGWQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12525
Length:	898 (807)
Sequences:	11640 (7549)
Seq/√Len:	265.7

ECOLI - ATMA ATKB ATZN
BACSU - ATCL ZOSA CADA
HALSA - ATKB Q9HSN5
SULSO - Q97VH4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
197_L	253_A	7.009	1.00
66_Q	165_D	5.126	1.00
368_D	634_H	4.499	1.00
605_A	631_R	4.327	1.00
185_I	197_L	4.046	1.00
76_H	181_P	3.888	1.00
462_H	519_Y	3.833	1.00
80_K	177_D	3.732	1.00
387_N	508_Q	3.664	1.00
438_Q	457_A	3.662	1.00
68_E	72_A	3.622	1.00
69_V	73_R	3.578	1.00
580_C	613_L	3.480	1.00
600_S	603_E	3.340	1.00
71_S	75_Q	3.326	1.00
627_T	651_A	3.291	1.00
402_S	538_E	3.249	1.00
609_Q	632_E	3.245	1.00
207_V	246_V	3.218	1.00
560_A	755_Q	3.163	1.00
197_L	240_C	3.132	1.00
68_E	71_S	3.088	1.00
601_D	624_R	3.083	1.00
693_A	756_K	3.058	1.00
156_T	173_E	3.045	1.00
380_Q	549_E	2.976	1.00
181_P	258_T	2.922	1.00
351_Q	683_E	2.894	1.00
501_V	504_T	2.830	1.00
491_D	494_M	2.824	1.00
464_Q	519_Y	2.817	1.00
550_T	677_S	2.800	1.00
467_C	535_L	2.780	1.00
82_P	260_A	2.774	1.00
479_S	534_D	2.759	1.00
185_I	253_A	2.743	1.00
205_L	251_A	2.740	1.00
184_I	200_L	2.687	1.00
556_K	560_A	2.679	1.00
73_R	258_T	2.609	1.00
103_I	107_I	2.598	1.00
440_I	463_H	2.576	1.00
160_L	252_Q	2.568	1.00
398_R	517_T	2.566	1.00
88_P	91_V	2.564	1.00
160_L	171_W	2.563	1.00
201_Q	252_Q	2.542	1.00
517_T	536_I	2.523	1.00
457_A	463_H	2.488	1.00
171_W	186_K	2.475	1.00
630_K	651_A	2.454	1.00
207_V	240_C	2.384	1.00
239_L	256_I	2.379	1.00
467_C	474_I	2.312	1.00
73_R	78_E	2.301	1.00
597_E	621_H	2.299	1.00
278_P	286_S	2.294	1.00
87_S	95_V	2.277	1.00
451_R	477_V	2.271	1.00
66_Q	172_L	2.265	1.00
453_S	465_L	2.253	1.00
609_Q	634_H	2.253	1.00
516_A	535_L	2.247	1.00
505_L	542_A	2.232	1.00
402_S	466_V	2.204	1.00
70_E	74_E	2.183	1.00
78_E	177_D	2.169	1.00
185_I	194_P	2.167	1.00
495_L	499_K	2.156	1.00
564_T	612_T	2.145	1.00
263_W	266_Q	2.138	1.00
850_A	854_S	2.124	1.00
158_T	171_W	2.102	1.00
78_E	178_Q	2.098	1.00
866_P	869_Y	2.089	1.00
179_L	255_V	2.085	1.00
89_W	136_F	2.082	1.00
197_L	256_I	2.077	1.00
657_S	669_A	2.076	1.00
307_N	317_A	2.065	1.00
133_L	137_I	2.056	1.00
605_A	628_L	2.039	1.00
577_A	581_H	2.034	1.00
158_T	188_A	2.034	1.00
205_L	246_V	2.029	1.00
351_Q	686_I	2.022	1.00
503_D	574_L	2.016	1.00
187_L	193_I	2.009	1.00
563_I	685_V	2.004	1.00
555_L	585_L	1.994	1.00
240_C	253_A	1.993	1.00
66_Q	70_E	1.988	1.00
453_S	467_C	1.980	1.00
236_C	241_F	1.979	1.00
498_I	537_L	1.969	1.00
589_E	610_R	1.968	1.00
156_T	175_P	1.968	1.00
160_L	186_K	1.960	1.00
500_R	504_T	1.953	1.00
605_A	632_E	1.945	1.00
243_G	264_F	1.941	1.00
558_L	682_E	1.940	1.00
514_A	537_L	1.939	1.00
199_I	202_A	1.932	1.00
193_I	246_V	1.921	1.00
553_P	557_A	1.910	1.00
355_V	671_I	1.908	1.00
496_R	500_R	1.904	1.00
566_K	629_L	1.903	1.00
180_V	258_T	1.899	1.00
423_E	427_E	1.897	1.00
97_Y	132_T	1.893	1.00
89_W	93_L	1.862	1.00
304_L	321_A	1.861	1.00
552_A	556_K	1.858	1.00
186_K	252_Q	1.854	1.00
550_T	553_P	1.852	1.00
179_L	185_I	1.851	1.00
494_M	497_K	1.832	1.00
592_I	595_D	1.831	1.00
474_I	516_A	1.829	1.00
557_A	686_I	1.827	1.00
367_M	637_G	1.810	1.00
65_N	69_V	1.792	1.00
398_R	401_H	1.788	1.00
591_V	599_L	1.785	1.00
67_A	71_S	1.780	1.00
199_I	240_C	1.774	1.00
438_Q	456_V	1.772	1.00
547_P	583_V	1.763	1.00
227_Q	231_S	1.761	1.00
71_S	74_E	1.761	1.00
591_V	611_T	1.757	1.00
70_E	73_R	1.754	1.00
353_V	680_V	1.754	1.00
385_L	424_G	1.753	1.00
160_L	184_I	1.748	1.00
518_K	534_D	1.739	1.00
195_A	255_V	1.731	1.00
517_T	538_E	1.727	1.00
480_Q	536_I	1.693	1.00
113_Y	121_A	1.684	1.00
503_D	507_R	1.667	1.00
65_N	165_D	1.663	1.00
408_H	439_K	1.663	1.00
476_N	495_L	1.661	1.00
440_I	457_A	1.653	1.00
857_A	864_A	1.652	1.00
492_D	496_R	1.645	1.00
525_G	531_D	1.638	1.00
849_I	855_P	1.638	1.00
499_K	503_D	1.633	1.00
553_P	556_K	1.614	1.00
175_P	178_Q	1.610	1.00
285_I	337_V	1.609	1.00
690_R	749_V	1.609	1.00
352_K	675_E	1.602	1.00
206_F	248_S	1.585	1.00
799_Q	803_Q	1.575	1.00
87_S	91_V	1.574	1.00
98_R	103_I	1.572	1.00
378_L	583_V	1.572	1.00
478_C	516_A	1.570	1.00
465_L	520_L	1.567	1.00
512_V	540_Y	1.565	1.00
389_T	501_V	1.565	1.00
400_L	424_G	1.564	1.00
784_F	788_W	1.563	1.00
65_N	68_E	1.557	1.00
109_G	125_A	1.551	1.00
354_I	674_L	1.550	1.00
849_I	853_F	1.546	1.00
453_S	532_E	1.541	1.00
606_N	610_R	1.540	1.00
200_L	254_M	1.530	1.00
174_I	178_Q	1.527	1.00
122_G	126_L	1.525	1.00
199_I	251_A	1.522	1.00
569_T	576_A	1.518	1.00
871_P	875_A	1.506	1.00
798_T	801_L	1.505	1.00
294_R	298_V	1.504	1.00
199_I	253_A	1.502	1.00
397_E	401_H	1.489	1.00
627_T	631_R	1.479	1.00
402_S	515_V	1.479	1.00
628_L	631_R	1.479	1.00
507_R	574_L	1.472	1.00
73_R	178_Q	1.471	1.00
492_D	495_L	1.465	1.00
253_A	256_I	1.458	1.00
305_L	309_Y	1.449	1.00
404_W	425_T	1.444	1.00
95_V	98_R	1.444	1.00
140_A	144_K	1.444	1.00
206_F	220_E	1.443	1.00
157_A	179_L	1.442	1.00
649_L	665_A	1.438	1.00
158_T	173_E	1.428	1.00
800_T	803_Q	1.427	1.00
83_A	150_K	1.423	1.00
599_L	607_L	1.418	1.00
637_G	656_I	1.411	1.00
450_R	470_A	1.403	1.00
352_K	674_L	1.403	1.00
187_L	246_V	1.401	1.00
510_L	542_A	1.400	1.00
198_R	256_I	1.397	1.00
519_Y	536_I	1.389	1.00
455_V	520_L	1.389	1.00
840_M	844_V	1.383	1.00
464_Q	517_T	1.380	1.00
386_E	582_E	1.376	1.00
801_L	869_Y	1.369	1.00
630_K	653_D	1.369	1.00
136_F	140_A	1.360	1.00
297_L	301_P	1.355	1.00
773_G	784_F	1.354	1.00
586_D	589_E	1.350	1.00
867_L	871_P	1.349	1.00
765_L	769_M	1.328	1.00
449_R	532_E	1.318	1.00
451_R	532_E	1.313	1.00
184_I	254_M	1.311	1.00
500_R	503_D	1.309	1.00
157_A	176_I	1.307	1.00
885_Q	888_K	1.306	1.00
287_R	291_L	1.305	1.00
369_I	566_K	1.295	1.00
182_G	254_M	1.291	1.00
198_R	254_M	1.287	1.00
367_M	654_I	1.283	1.00
504_T	508_Q	1.281	1.00
474_I	478_C	1.281	1.00
106_T	128_V	1.278	1.00
715_V	781_I	1.274	1.00
573_E	590_V	1.267	1.00
478_C	537_L	1.265	1.00
604_L	624_R	1.262	1.00
544_L	582_E	1.259	1.00
471_L	502_T	1.254	1.00
568_L	625_I	1.251	1.00
608_A	632_E	1.250	1.00
573_E	592_I	1.248	1.00
773_G	781_I	1.244	1.00
165_D	170_G	1.244	1.00
371_C	629_L	1.244	1.00
193_I	240_C	1.244	1.00
515_V	541_I	1.243	1.00
603_E	606_N	1.240	1.00
347_K	687_E	1.238	1.00
110_A	114_A	1.235	1.00
144_K	147_D	1.229	1.00
868_S	871_P	1.226	1.00
419_T	423_E	1.223	1.00
399_V	539_G	1.220	1.00
187_L	240_C	1.219	1.00
576_A	615_A	1.218	1.00
839_I	843_I	1.216	1.00
421_V	541_I	1.215	1.00
786_L	790_V	1.215	1.00
67_A	70_E	1.212	1.00
557_A	560_A	1.212	1.00
766_G	770_I	1.211	1.00
760_W	763_A	1.211	1.00
777_S	781_I	1.207	1.00
452_M	468_K	1.207	1.00
602_D	606_N	1.204	1.00
72_A	76_H	1.203	1.00
318_A	322_L	1.196	1.00
837_L	841_T	1.196	1.00
683_E	686_I	1.191	1.00
93_L	136_F	1.189	1.00
398_R	466_V	1.188	1.00
458_E	462_H	1.186	1.00
687_E	690_R	1.182	1.00
403_A	541_I	1.181	1.00
573_E	577_A	1.180	1.00
607_L	611_T	1.179	1.00
608_A	628_L	1.179	1.00
474_I	514_A	1.179	1.00
283_Q	287_R	1.168	1.00
106_T	110_A	1.165	1.00
627_T	630_K	1.164	1.00
848_G	855_P	1.163	1.00
277_E	630_K	1.162	1.00
769_M	773_G	1.162	1.00
505_L	510_L	1.160	1.00
785_C	789_W	1.155	1.00
278_P	283_Q	1.153	1.00
456_V	466_V	1.148	1.00
873_L	877_L	1.148	1.00
200_L	252_Q	1.142	1.00
386_E	544_L	1.140	1.00
550_T	679_M	1.140	1.00
189_A	446_D	1.136	1.00
371_C	568_L	1.134	1.00
455_V	465_L	1.133	1.00
878_A	882_T	1.132	1.00
472_Q	572_S	1.129	1.00
209_Q	221_K	1.128	1.00
126_L	130_I	1.120	1.00
228_P	231_S	1.119	1.00
518_K	533_S	1.118	1.00
158_T	191_D	1.116	1.00
875_A	879_G	1.116	1.00
882_T	886_L	1.112	1.00
837_L	840_M	1.111	1.00
604_L	608_A	1.106	1.00
459_N	462_H	1.104	1.00
198_R	239_L	1.103	1.00
443_I	453_S	1.101	1.00
465_L	535_L	1.100	1.00
580_C	585_L	1.099	1.00
782_L	786_L	1.093	1.00
568_L	617_L	1.091	1.00
496_R	499_K	1.091	1.00
69_V	78_E	1.089	1.00
158_T	186_K	1.087	1.00
767_R	771_F	1.086	1.00
766_G	773_G	1.086	1.00
231_S	234_L	1.085	1.00
118_L	122_G	1.083	1.00
449_R	453_S	1.082	1.00
641_D	644_N	1.082	1.00
383_I	418_D	1.074	1.00
240_C	246_V	1.074	1.00
781_I	784_F	1.071	1.00
387_N	505_L	1.069	1.00
709_N	737_Y	1.068	1.00
86_P	147_D	1.068	1.00
257_A	261_N	1.068	1.00
831_S	835_W	1.065	1.00
595_D	598_T	1.065	1.00
835_W	838_M	1.064	1.00
826_V	830_Q	1.061	1.00
473_E	476_N	1.061	1.00
450_R	473_E	1.060	1.00
773_G	780_D	1.059	1.00
602_D	605_A	1.059	1.00
518_K	532_E	1.057	1.00
202_A	223_A	1.056	1.00
437_W	466_V	1.055	1.00
199_I	223_A	1.055	1.00
663_D	666_R	1.054	1.00
232_N	235_E	1.053	1.00
385_L	421_V	1.053	1.00
87_S	92_H	1.049	1.00
819_H	842_V	1.048	1.00
836_P	840_M	1.043	1.00
497_K	501_V	1.041	1.00
780_D	784_F	1.040	1.00
93_L	133_L	1.038	1.00
605_A	608_A	1.037	1.00
696_L	763_A	1.036	1.00
236_C	263_W	1.036	1.00
417_L	421_V	1.035	1.00
451_R	467_C	1.035	1.00
171_W	252_Q	1.035	1.00
370_L	637_G	1.033	1.00
357_H	670_D	1.033	1.00
805_G	869_Y	1.030	1.00
604_L	628_L	1.029	1.00
497_K	500_R	1.027	1.00
385_L	541_I	1.024	1.00
776_S	780_D	1.023	1.00
193_I	207_V	1.019	1.00
437_W	456_V	1.019	1.00
711_F	781_I	1.016	1.00
521_P	524_E	1.016	1.00
417_L	543_F	1.016	1.00
784_F	806_W	1.016	1.00
73_R	76_H	1.014	1.00
92_H	140_A	1.012	1.00
388_H	399_V	1.011	1.00
765_L	768_F	1.011	1.00
502_T	506_N	1.009	1.00
567_I	576_A	1.004	1.00
593_G	621_H	1.003	1.00
384_V	427_E	1.002	1.00
93_L	97_Y	1.002	1.00
508_Q	582_E	1.001	1.00
591_V	607_L	1.001	1.00
69_V	72_A	1.000	1.00
480_Q	534_D	1.000	1.00
747_D	822_R	0.995	1.00
409_Y	422_L	0.995	1.00
473_E	477_V	0.994	1.00
591_V	596_I	0.992	1.00
614_F	629_L	0.992	1.00
814_Q	817_I	0.990	1.00
353_V	684_G	0.989	1.00
113_Y	125_A	0.989	1.00
308_G	314_W	0.989	1.00
884_T	888_K	0.988	1.00
346_V	350_K	0.986	1.00
551_T	583_V	0.984	1.00
475_L	499_K	0.982	1.00
233_P	236_C	0.982	1.00
93_L	132_T	0.980	1.00
869_Y	872_W	0.979	1.00
405_L	456_V	0.979	1.00
439_K	442_E	0.977	1.00
246_V	251_A	0.976	1.00
202_A	240_C	0.971	1.00
852_P	855_P	0.971	1.00
90_W	94_W	0.967	1.00
702_T	741_Q	0.964	1.00
506_N	574_L	0.963	1.00
817_I	820_M	0.961	1.00
765_L	773_G	0.960	1.00
654_I	671_I	0.960	1.00
559_K	586_D	0.956	1.00
499_K	502_T	0.955	1.00
544_L	547_P	0.952	1.00
857_A	862_L	0.951	1.00
369_I	629_L	0.951	1.00
589_E	607_L	0.951	1.00
805_G	873_L	0.950	1.00
385_L	543_F	0.949	1.00
91_V	94_W	0.949	1.00
290_M	294_R	0.949	1.00
137_I	141_R	0.948	1.00
635_V	653_D	0.947	1.00
401_H	437_W	0.947	1.00
424_G	541_I	0.946	1.00
578_K	582_E	0.944	1.00
270_R	620_M	0.942	1.00
808_V	873_L	0.939	1.00
352_K	680_V	0.939	1.00
408_H	442_E	0.939	1.00
188_A	191_D	0.938	1.00
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869_Y	873_L	0.937	1.00
283_Q	653_D	0.937	1.00
558_L	678_L	0.934	1.00
559_K	565_V	0.933	1.00
845_M	855_P	0.931	1.00
716_A	724_P	0.931	1.00
626_V	638_F	0.929	1.00
398_R	402_S	0.929	1.00
111_I	318_A	0.929	1.00
66_Q	69_V	0.928	1.00
608_A	625_I	0.927	1.00
781_I	785_C	0.922	1.00
502_T	540_Y	0.922	1.00
421_V	425_T	0.919	1.00
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192_M	667_E	0.915	1.00
831_S	834_S	0.913	1.00
475_L	498_I	0.910	1.00
159_V	172_L	0.909	1.00
92_H	136_F	0.909	1.00
781_I	788_W	0.908	1.00
567_I	580_C	0.908	1.00
399_V	403_A	0.906	1.00
443_I	449_R	0.905	1.00
554_A	679_M	0.905	1.00
389_T	505_L	0.904	1.00
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784_F	787_M	0.900	1.00
165_D	172_L	0.900	1.00
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558_L	565_V	0.898	1.00
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479_S	536_I	0.896	1.00
313_D	316_E	0.895	1.00
737_Y	814_Q	0.893	1.00
498_I	540_Y	0.891	1.00
331_E	734_N	0.891	1.00
403_A	515_V	0.891	1.00
401_H	458_E	0.889	1.00
118_L	121_A	0.887	1.00
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407_S	421_V	0.881	1.00
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845_M	848_G	0.879	1.00
179_L	194_P	0.879	1.00
819_H	822_R	0.879	1.00
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405_L	437_W	0.879	1.00
380_Q	546_P	0.878	1.00
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603_E	607_L	0.877	1.00
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304_L	318_A	0.875	1.00
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586_D	590_V	0.863	1.00
465_L	518_K	0.862	1.00
780_D	813_S	0.862	1.00
507_R	577_A	0.861	1.00
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849_I	854_S	0.859	1.00
404_W	407_S	0.859	1.00
298_V	302_V	0.858	1.00
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463_H	523_R	0.858	1.00
768_F	772_F	0.857	1.00
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466_V	515_V	0.851	1.00
552_A	582_E	0.851	1.00
222_A	237_D	0.851	1.00
278_P	282_Q	0.849	1.00
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80_K	83_A	0.847	1.00
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227_Q	238_T	0.843	0.99
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749_V	753_Q	0.841	0.99
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836_P	839_I	0.837	0.99
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367_M	685_V	0.828	0.99
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649_L	655_G	0.824	0.99
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343_R	746_F	0.821	0.99
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403_A	424_G	0.792	0.99
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185_I	255_V	0.779	0.99
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787_M	805_G	0.778	0.99
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266_Q	620_M	0.766	0.99
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312_G	316_E	0.731	0.99
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213_T	219_V	0.715	0.98
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296_M	328_L	0.608	0.96
708_G	781_I	0.608	0.96
203_R	250_T	0.608	0.96
554_A	680_V	0.607	0.96
87_S	90_W	0.607	0.96
865_L	869_Y	0.607	0.96
375_T	571_D	0.606	0.95
838_M	841_T	0.605	0.95
72_A	181_P	0.604	0.95
824_R	827_P	0.604	0.95
597_E	624_R	0.603	0.95
373_D	641_D	0.603	0.95
593_G	596_I	0.602	0.95
317_A	320_F	0.602	0.95
463_H	520_L	0.602	0.95
231_S	236_C	0.602	0.95
443_I	451_R	0.601	0.95
106_T	125_A	0.601	0.95
778_I	781_I	0.600	0.95
551_T	555_L	0.600	0.95
467_C	516_A	0.598	0.95
601_D	605_A	0.598	0.95
713_V	716_A	0.597	0.95
179_L	197_L	0.597	0.95
351_Q	687_E	0.597	0.95
709_N	725_M	0.596	0.95
787_M	790_V	0.596	0.95
431_R	435_S	0.596	0.95
373_D	644_N	0.595	0.95
565_V	678_L	0.595	0.95
200_L	253_A	0.595	0.95
327_G	730_L	0.595	0.95
697_K	747_D	0.595	0.95
780_D	788_W	0.594	0.95
69_V	165_D	0.594	0.95
702_T	705_S	0.594	0.95
866_P	872_W	0.594	0.95
72_A	75_Q	0.594	0.95
127_M	132_T	0.593	0.95
533_S	536_I	0.592	0.95
850_A	856_L	0.592	0.95
425_T	429_S	0.592	0.95
717_S	720_L	0.592	0.95
596_I	600_S	0.591	0.95
417_L	447_F	0.590	0.95
544_L	578_K	0.590	0.95
784_F	790_V	0.589	0.95
108_L	124_I	0.589	0.95
209_Q	213_T	0.589	0.95
212_L	241_F	0.589	0.95
856_L	862_L	0.589	0.95
291_L	294_R	0.589	0.95
266_Q	269_G	0.589	0.95
274_Q	651_A	0.588	0.95
748_N	834_S	0.588	0.95
406_N	409_Y	0.588	0.95
296_M	299_M	0.588	0.95
779_F	883_L	0.587	0.95
765_L	781_I	0.587	0.95
475_L	478_C	0.587	0.95
423_E	426_D	0.586	0.95
834_S	838_M	0.586	0.95
773_G	788_W	0.585	0.95
286_S	290_M	0.585	0.95
870_F	874_V	0.585	0.95
850_A	855_P	0.585	0.95
557_A	682_E	0.584	0.94
414_K	418_D	0.584	0.94
374_K	570_G	0.584	0.94
807_F	813_S	0.583	0.94
862_L	865_L	0.583	0.94
701_M	741_Q	0.582	0.94
401_H	405_L	0.582	0.94
768_F	771_F	0.582	0.94
702_T	709_N	0.582	0.94
69_V	174_I	0.581	0.94
287_R	290_M	0.581	0.94
713_V	730_L	0.581	0.94
831_S	836_P	0.581	0.94
701_M	705_S	0.580	0.94
698_Y	701_M	0.580	0.94
813_S	817_I	0.580	0.94
111_I	115_T	0.580	0.94
807_F	815_T	0.579	0.94
558_L	685_V	0.578	0.94
307_N	311_K	0.578	0.94
881_M	888_K	0.577	0.94
76_H	261_N	0.577	0.94
611_T	625_I	0.577	0.94
726_L	803_Q	0.576	0.94
399_V	538_E	0.576	0.94
206_F	247_V	0.576	0.94
94_W	106_T	0.576	0.94
225_T	238_T	0.576	0.94
765_L	780_D	0.576	0.94
705_S	737_Y	0.576	0.94
847_V	854_S	0.576	0.94
766_G	788_W	0.575	0.94
281_F	341_L	0.575	0.94
107_I	111_I	0.574	0.94
100_P	289_S	0.574	0.94
336_I	698_Y	0.574	0.94
494_M	498_I	0.573	0.94
382_K	660_G	0.573	0.94
288_V	699_I	0.573	0.94
821_I	824_R	0.572	0.94
147_D	150_K	0.572	0.94
854_S	857_A	0.571	0.94
463_H	524_E	0.571	0.94
537_L	540_Y	0.571	0.94
781_I	786_L	0.570	0.94
302_V	306_I	0.570	0.94
295_F	299_M	0.570	0.94
98_R	102_N	0.570	0.94
434_A	437_W	0.570	0.94
510_L	544_L	0.570	0.94
639_M	681_L	0.570	0.94
694_N	697_K	0.569	0.94
437_W	458_E	0.568	0.94
608_A	629_L	0.567	0.94
304_L	308_G	0.567	0.94
470_A	616_R	0.566	0.94
872_W	877_L	0.565	0.93
382_K	427_E	0.565	0.93
693_A	750_D	0.565	0.93
288_V	296_M	0.564	0.93
708_G	712_S	0.564	0.93
659_D	666_R	0.563	0.93
285_I	289_S	0.562	0.93
396_S	400_L	0.562	0.93
347_K	350_K	0.562	0.93
436_R	459_N	0.561	0.93
518_K	524_E	0.561	0.93
709_N	810_G	0.560	0.93
86_P	90_W	0.560	0.93
187_L	197_L	0.560	0.93
157_A	174_I	0.560	0.93
803_Q	817_I	0.560	0.93
376_G	379_T	0.559	0.93
304_L	317_A	0.559	0.93
154_S	176_I	0.559	0.93
181_P	261_N	0.558	0.93
466_V	517_T	0.557	0.93
779_F	879_G	0.557	0.93
880_Y	884_T	0.557	0.93
398_R	536_I	0.556	0.93
498_I	501_V	0.556	0.93
218_P	247_V	0.556	0.93
759_R	763_A	0.556	0.93
766_G	781_I	0.556	0.93
864_A	871_P	0.555	0.93
558_L	637_G	0.555	0.93
740_S	744_I	0.554	0.93
292_L	841_T	0.553	0.93
456_V	464_Q	0.552	0.93
876_I	880_Y	0.551	0.93
282_Q	359_D	0.551	0.93
180_V	183_D	0.551	0.93
127_M	737_Y	0.551	0.93
591_V	595_D	0.550	0.93
730_L	735_L	0.550	0.93
702_T	737_Y	0.550	0.93
368_D	629_L	0.550	0.93
848_G	854_S	0.550	0.93
402_S	405_L	0.549	0.92
198_R	238_T	0.549	0.92
818_V	838_M	0.549	0.92
73_R	180_V	0.549	0.92
808_V	816_L	0.548	0.92
90_W	93_L	0.547	0.92
472_Q	502_T	0.547	0.92
293_I	297_L	0.546	0.92
348_L	355_V	0.546	0.92
827_P	831_S	0.546	0.92
807_F	811_L	0.546	0.92
215_E	642_G	0.545	0.92
446_D	473_E	0.544	0.92
752_E	755_Q	0.544	0.92
788_W	806_W	0.543	0.92
596_I	599_L	0.543	0.92
778_I	782_L	0.543	0.92
554_A	678_L	0.543	0.92
769_M	784_F	0.543	0.92
769_M	776_S	0.542	0.92
658_V	676_K	0.542	0.92
796_P	800_T	0.542	0.92
791_F	795_T	0.542	0.92
638_F	648_A	0.542	0.92
112_S	121_A	0.541	0.92
833_A	839_I	0.541	0.92
393_G	397_E	0.541	0.92
442_E	454_V	0.541	0.92
807_F	851_L	0.540	0.92
157_A	194_P	0.540	0.92
92_H	96_C	0.540	0.92
511_R	641_D	0.540	0.92
689_R	750_D	0.540	0.92
437_W	459_N	0.539	0.92
85_Q	90_W	0.539	0.92
661_A	676_K	0.539	0.92
809_V	873_L	0.538	0.92
475_L	537_L	0.538	0.92
471_L	514_A	0.538	0.92
506_N	575_V	0.538	0.92
698_Y	745_P	0.538	0.92
808_V	811_L	0.538	0.92
773_G	785_C	0.538	0.92
436_R	458_E	0.537	0.92
468_K	513_V	0.537	0.92
109_G	128_V	0.537	0.92
208_A	247_V	0.537	0.92
250_T	442_E	0.536	0.92
402_S	464_Q	0.536	0.92
131_S	134_L	0.536	0.92
422_L	425_T	0.535	0.92
128_V	132_T	0.535	0.92
804_S	816_L	0.535	0.92
872_W	875_A	0.535	0.92
832_C	838_M	0.535	0.92
327_G	741_Q	0.535	0.92
148_A	667_E	0.534	0.91
730_L	734_N	0.534	0.91
470_A	511_R	0.534	0.91
571_D	642_G	0.534	0.91
277_E	283_Q	0.533	0.91
807_F	810_G	0.533	0.91
856_L	860_L	0.533	0.91
721_P	789_W	0.532	0.91
145_A	148_A	0.532	0.91
547_P	582_E	0.532	0.91
327_G	709_N	0.531	0.91
384_V	544_L	0.531	0.91
65_N	462_H	0.530	0.91
518_K	535_L	0.530	0.91
171_W	188_A	0.530	0.91
111_I	322_L	0.530	0.91
549_E	552_A	0.530	0.91
701_M	738_D	0.529	0.91
399_V	541_I	0.529	0.91
698_Y	741_Q	0.529	0.91
206_F	218_P	0.528	0.91
496_R	503_D	0.528	0.91
208_A	245_T	0.528	0.91
819_H	839_I	0.527	0.91
783_T	879_G	0.527	0.91
292_L	329_T	0.527	0.91
127_M	131_S	0.527	0.91
808_V	815_T	0.526	0.91
306_I	714_L	0.526	0.91
524_E	531_D	0.526	0.91
442_E	452_M	0.526	0.91
239_L	254_M	0.525	0.91
230_H	598_T	0.525	0.91
447_F	511_R	0.524	0.91
142_S	145_A	0.523	0.91
825_R	828_F	0.522	0.91
775_I	779_F	0.522	0.91
67_A	75_Q	0.521	0.90
140_A	143_T	0.521	0.90
215_E	375_T	0.520	0.90
815_T	818_V	0.520	0.90
228_P	233_P	0.520	0.90
817_I	821_I	0.519	0.90
816_L	820_M	0.519	0.90
843_I	846_I	0.518	0.90
92_H	95_V	0.518	0.90
775_I	887_V	0.518	0.90
794_N	797_E	0.517	0.90
378_L	547_P	0.517	0.90
771_F	775_I	0.516	0.90
735_L	738_D	0.516	0.90
377_T	571_D	0.515	0.90
804_S	808_V	0.515	0.90
776_S	784_F	0.514	0.90
715_V	719_F	0.514	0.90
588_G	612_T	0.513	0.90
438_Q	458_E	0.513	0.90
103_I	106_T	0.513	0.90
62_E	67_A	0.512	0.90
775_I	783_T	0.512	0.90
207_V	221_K	0.512	0.90
400_L	425_T	0.512	0.90
705_S	734_N	0.511	0.90
810_G	817_I	0.511	0.90
383_I	543_F	0.511	0.90
813_S	877_L	0.510	0.90
100_P	104_L	0.509	0.89
374_K	641_D	0.509	0.89
472_Q	616_R	0.508	0.89
366_A	759_R	0.508	0.89
403_A	407_S	0.508	0.89
616_R	619_P	0.508	0.89
97_Y	136_F	0.508	0.89
404_W	430_A	0.507	0.89
568_L	614_F	0.507	0.89
174_I	255_V	0.506	0.89
805_G	809_V	0.506	0.89
835_W	840_M	0.506	0.89
864_A	874_V	0.505	0.89
693_A	697_K	0.505	0.89
63_G	180_V	0.504	0.89
471_L	583_V	0.503	0.89
476_N	479_S	0.503	0.89
874_V	878_A	0.503	0.89
239_L	257_A	0.503	0.89
317_A	321_A	0.503	0.89
227_Q	230_H	0.502	0.89
551_T	554_A	0.502	0.89
765_L	777_S	0.502	0.89
782_L	876_I	0.501	0.89
732_I	848_G	0.501	0.89
398_R	403_A	0.501	0.89
343_R	691_T	0.501	0.89
327_G	702_T	0.501	0.89
328_L	710_V	0.500	0.89
772_F	775_I	0.500	0.89

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3ixzA	1	0.9588	100	0.201	Contact Map
2zxeA	1	0.9532	100	0.202	Contact Map
3ar4A	1	0.9465	100	0.204	Contact Map
1mhsA	2	0.9443	100	0.264	Contact Map
3b8cA	1	0.8931	100	0.28	Contact Map
4bbjA	1	0.6604	100	0.548	Contact Map
4umwA	1	0.637	100	0.559	Contact Map
3j09A	2	0.7238	100	0.564	Contact Map
3j08A	2	0.6826	100	0.567	Contact Map
3a1cA	2	0.304	100	0.84	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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