GREMLIN Database
ATPB - ATP synthase subunit beta
UniProt: P0ABB4 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10101
Length: 460 (416)
Sequences: 7650 (2646)
Seq/√Len: 129.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
90_N94_E7.9331.00
142_K237_D4.8041.00
178_A224_G4.4811.00
323_S336_D4.2681.00
16_V54_T3.7651.00
133_V335_V3.4271.00
28_D71_D3.3341.00
361_V397_I3.2241.00
30_L54_T3.0391.00
87_R97_D2.9951.00
74_H77_E2.9161.00
410_V413_G2.8351.00
31_E70_K2.6031.00
225_L295_Q2.5751.00
176_V228_A2.5231.00
82_K236_R2.5201.00
125_E142_K2.5201.00
140_F294_V2.4751.00
77_E107_R2.4591.00
30_L69_V2.4271.00
350_V355_Y2.4261.00
41_L54_T2.3351.00
83_A105_E2.3301.00
360_G363_S2.3161.00
228_A291_I2.3011.00
197_S201_D2.3001.00
132_K409_E2.2751.00
158_V405_F2.2561.00
89_M227_M2.2461.00
25_R28_D2.1991.00
369_Q372_K2.1861.00
16_V69_V2.1751.00
326_I331_I2.1381.00
15_D51_I2.1281.00
188_N192_H2.1221.00
206_V227_M2.1181.00
304_L321_V2.1001.00
174_Y236_R2.0351.00
394_A398_Q2.0321.00
352_Q356_D2.0131.00
137_M361_V2.0131.00
6_I63_L1.9511.00
108_W112_R1.9421.00
360_G389_L1.9351.00
229_E282_R1.9111.00
136_L414_S1.8791.00
198_N201_D1.8621.00
8_Q15_D1.8621.00
136_L400_F1.8571.00
140_F320_V1.8421.00
108_W226_T1.8371.00
41_L44_Q1.8301.00
31_E38_R1.8291.00
7_V17_E1.8081.00
108_W230_K1.7811.00
192_H195_T1.7751.00
191_Y205_L1.7521.00
372_K376_A1.7401.00
375_I391_V1.7391.00
204_S227_M1.7281.00
128_E135_D1.7221.00
331_I402_S1.7191.00
174_Y231_F1.7071.00
420_S423_D1.7061.00
329_L398_Q1.6961.00
399_R402_S1.6901.00
331_I398_Q1.6681.00
357_T419_V1.6631.00
297_V312_T1.6601.00
174_Y204_S1.6591.00
151_G154_V1.6501.00
79_P107_R1.6431.00
28_D73_E1.6391.00
192_H196_D1.6281.00
330_G359_R1.6221.00
176_V227_M1.6051.00
24_P44_Q1.5991.00
33_Q68_D1.5691.00
106_E234_E1.5631.00
127_L173_G1.5471.00
89_M206_V1.5371.00
139_P345_L1.5361.00
82_K230_K1.5351.00
125_E285_S1.5201.00
99_K195_T1.4961.00
180_V220_V1.4731.00
237_D290_S1.4731.00
83_A103_G1.4721.00
95_P100_G1.4621.00
87_R100_G1.4591.00
84_T227_M1.4581.00
147_G316_L1.4541.00
83_A104_E1.4511.00
87_R99_K1.4491.00
78_V227_M1.4451.00
32_V41_L1.4391.00
404_P407_V1.4231.00
193_E347_P1.4201.00
16_V19_P1.4191.00
7_V51_I1.4121.00
382_E392_A1.4111.00
345_L358_A1.4071.00
5_K68_D1.4061.00
178_A242_V1.3991.00
76_I110_I1.3941.00
329_L372_K1.3791.00
90_N212_E1.3781.00
392_A395_R1.3751.00
108_W233_D1.3741.00
221_A279_L1.3631.00
129_T140_F1.3531.00
6_I67_L1.3511.00
78_V223_T1.3461.00
134_I320_V1.3381.00
230_K234_E1.3371.00
24_P30_L1.3311.00
134_I163_L1.3281.00
306_D309_P1.3241.00
196_D199_V1.2901.00
367_R370_E1.2891.00
74_H107_R1.2881.00
252_G275_E1.2871.00
179_G187_G1.2841.00
31_E72_L1.2781.00
359_R362_Q1.2761.00
246_Y250_L1.2701.00
88_I191_Y1.2701.00
87_R95_P1.2701.00
238_V291_I1.2681.00
225_L283_I1.2621.00
413_G417_K1.2611.00
171_H237_D1.2601.00
280_Q315_H1.2591.00
79_P104_E1.2571.00
363_S387_D1.2521.00
56_A60_S1.2481.00
3_T68_D1.2471.00
346_D355_Y1.2361.00
119_E287_K1.2321.00
389_L393_R1.2311.00
276_M312_T1.2261.00
9_V63_L1.2191.00
164_I203_V1.2181.00
212_E216_N1.2161.00
195_T200_I1.2100.99
31_E40_V1.2070.99
325_Q328_S1.2050.99
112_R233_D1.2000.99
235_G288_T1.1990.99
24_P43_V1.1970.99
138_C320_V1.1910.99
256_S264_S1.1880.99
158_V406_F1.1870.99
397_I421_L1.1850.99
85_L204_S1.1830.99
344_Q348_L1.1830.99
123_S141_A1.1780.99
60_S63_L1.1740.99
360_G364_I1.1680.99
225_L291_I1.1580.99
129_T294_V1.1470.99
17_E51_I1.1460.99
5_K17_E1.1420.99
385_E388_K1.1350.99
33_Q70_K1.1290.99
245_I312_T1.1280.99
85_L174_Y1.1230.99
116_S119_E1.1210.99
280_Q312_T1.1130.99
91_V223_T1.1110.99
355_Y359_R1.1100.99
351_G411_F1.1090.99
140_F292_T1.1080.99
331_I401_L1.1030.99
127_L167_I1.0980.99
106_E230_K1.0920.99
97_D100_G1.0880.99
146_V294_V1.0850.99
222_L275_E1.0840.99
15_D48_G1.0830.99
178_A240_L1.0780.99
82_K234_E1.0700.99
17_E50_G1.0670.99
309_P321_V1.0660.99
339_D369_Q1.0650.99
131_I134_I1.0570.99
354_H415_P1.0530.99
371_L375_I1.0510.99
184_T209_Q1.0480.99
121_S124_Q1.0450.98
131_I159_N1.0440.98
58_G216_N1.0420.98
151_G324_R1.0400.98
336_D339_D1.0390.98
29_A72_L1.0380.98
351_G354_H1.0320.98
104_E107_R1.0290.98
81_G84_T1.0250.98
180_V242_V1.0070.98
326_I402_S1.0050.98
392_A396_K1.0010.98
91_V216_N0.9980.98
302_D324_R0.9960.98
302_D305_T0.9940.98
33_Q38_R0.9940.98
87_R101_E0.9870.98
328_S339_D0.9850.98
299_V309_P0.9840.98
129_T135_D0.9770.98
30_L41_L0.9760.98
91_V96_V0.9750.98
409_E417_K0.9700.98
128_E411_F0.9680.97
151_G302_D0.9660.97
276_M315_H0.9660.97
245_I280_Q0.9640.97
119_E286_T0.9600.97
234_E238_V0.9590.97
84_T204_S0.9450.97
40_V43_V0.9400.97
225_L240_L0.9400.97
37_E42_E0.9390.97
108_W234_E0.9380.97
164_I241_F0.9380.97
64_R67_L0.9370.97
199_V203_V0.9370.97
354_H411_F0.9350.97
134_I138_C0.9340.97
164_I175_S0.9340.97
84_T89_M0.9330.97
126_L348_L0.9310.97
16_V30_L0.9270.97
299_V306_D0.9260.97
99_K102_I0.9240.97
33_Q67_L0.9200.97
34_N37_E0.9160.96
151_G310_A0.9140.96
28_D75_P0.9130.96
217_R254_E0.9110.96
204_S231_F0.9100.96
140_F146_V0.9080.96
39_L42_E0.9030.96
175_S178_A0.9020.96
346_D362_Q0.9020.96
137_M358_A0.9000.96
164_I177_F0.8980.96
191_Y195_T0.8970.96
133_V401_L0.8970.96
183_R186_E0.8970.96
325_Q369_Q0.8950.96
13_V259_L0.8950.96
146_V318_A0.8940.96
232_R238_V0.8910.96
182_E186_E0.8910.96
173_G237_D0.8910.96
48_G53_R0.8890.96
318_A343_R0.8880.96
276_M311_T0.8880.96
76_I219_R0.8880.96
58_G94_E0.8860.96
82_K231_F0.8850.96
91_V212_E0.8840.96
304_L309_P0.8830.96
189_D347_P0.8820.96
367_R387_D0.8800.96
139_P411_F0.8800.96
244_N296_A0.8730.95
285_S290_S0.8710.95
148_L160_M0.8700.95
224_G240_L0.8690.95
94_E101_E0.8690.95
87_R96_V0.8670.95
367_R371_L0.8630.95
389_L392_A0.8620.95
163_L239_L0.8560.95
87_R102_I0.8530.95
239_L294_V0.8520.95
248_Y279_L0.8520.95
345_L350_V0.8490.95
250_L300_P0.8480.95
380_M388_K0.8470.95
160_M241_F0.8460.95
283_I293_S0.8460.95
121_S286_T0.8450.95
128_E171_H0.8440.94
321_V324_R0.8430.94
345_L354_H0.8430.94
110_I223_T0.8380.94
357_T415_P0.8360.94
14_V32_V0.8330.94
9_V110_I0.8320.94
368_Y394_A0.8310.94
304_L339_D0.8270.94
176_V204_S0.8270.94
274_E277_G0.8230.94
34_N38_R0.8220.94
13_V53_R0.8210.94
121_S285_S0.8190.94
250_L268_Y0.8170.93
136_L418_Y0.8120.93
94_E107_R0.8120.93
14_V41_L0.8100.93
151_G303_D0.8100.93
32_V67_L0.8060.93
363_S367_R0.8040.93
10_I377_I0.8020.93
40_V94_E0.8020.93
350_V358_A0.8010.93
199_V202_K0.8000.93
125_E237_D0.8000.93
126_L139_P0.7980.93
102_I105_E0.7980.93
249_T276_M0.7970.93
135_D414_S0.7950.93
89_M102_I0.7930.92
141_A344_Q0.7880.92
383_L388_K0.7870.92
411_F415_P0.7870.92
37_E43_V0.7860.92
174_Y202_K0.7820.92
303_D310_A0.7770.92
363_S402_S0.7760.92
301_A306_D0.7760.92
365_L397_I0.7760.92
409_E415_P0.7750.92
28_D135_D0.7750.92
21_D52_V0.7750.92
350_V415_P0.7750.92
378_L383_L0.7730.91
382_E391_V0.7730.91
149_F309_P0.7720.91
180_V221_A0.7700.91
142_K290_S0.7700.91
356_D360_G0.7670.91
139_P350_V0.7650.91
208_G212_E0.7640.91
80_V226_T0.7610.91
222_L248_Y0.7580.91
90_N96_V0.7570.91
248_Y275_E0.7560.91
241_F296_A0.7530.90
6_I14_V0.7530.90
353_E419_V0.7510.90
87_R98_M0.7510.90
103_G106_E0.7500.90
364_I397_I0.7500.90
88_I96_V0.7500.90
361_V422_K0.7480.90
376_A385_E0.7470.90
76_I135_D0.7470.90
364_I389_L0.7460.90
174_Y238_V0.7460.90
230_K233_D0.7460.90
165_R202_K0.7450.90
182_E247_R0.7420.90
242_V279_L0.7420.90
96_V101_E0.7400.90
129_T134_I0.7390.90
58_G213_P0.7380.89
28_D72_L0.7380.89
128_E418_Y0.7370.89
323_S339_D0.7340.89
412_T416_G0.7310.89
268_Y303_D0.7300.89
173_G236_R0.7290.89
77_E109_A0.7280.89
409_E414_S0.7270.89
76_I223_T0.7270.89
106_E109_A0.7250.89
165_R406_F0.7240.89
59_S62_G0.7230.88
96_V207_Y0.7220.88
121_S287_K0.7200.88
122_N347_P0.7190.88
393_R424_T0.7150.88
373_D376_A0.7090.88
223_T226_T0.7080.87
123_S344_Q0.7070.87
139_P354_H0.7040.87
356_D359_R0.7030.87
357_T418_Y0.6980.87
218_L252_G0.6970.87
238_V254_E0.6970.87
57_M216_N0.6950.86
151_G267_G0.6950.86
265_A311_T0.6940.86
351_G415_P0.6920.86
310_A313_F0.6920.86
336_D369_Q0.6910.86
227_M231_F0.6900.86
187_G207_Y0.6880.86
385_E389_L0.6870.86
3_T70_K0.6860.86
10_I13_V0.6860.86
138_C341_T0.6850.86
38_R70_K0.6840.86
14_V60_S0.6840.86
354_H358_A0.6840.86
393_R396_K0.6830.86
372_K398_Q0.6810.85
101_E105_E0.6790.85
16_V52_V0.6790.85
368_Y372_K0.6790.85
272_L275_E0.6780.85
75_P109_A0.6740.85
150_G162_E0.6740.85
380_M383_L0.6740.85
79_P105_E0.6740.85
99_K200_I0.6720.85
113_A278_V0.6720.85
39_L58_G0.6710.85
183_R247_R0.6700.84
15_D53_R0.6690.84
321_V339_D0.6680.84
250_L311_T0.6670.84
218_L255_V0.6670.84
47_L65_R0.6660.84
371_L376_A0.6660.84
344_Q350_V0.6650.84
42_E219_R0.6630.84
167_I172_S0.6620.84
46_Q53_R0.6620.84
175_S203_V0.6610.84
373_D379_G0.6610.84
92_L95_P0.6590.83
160_M296_A0.6580.83
240_L283_I0.6560.83
365_L369_Q0.6550.83
83_A106_E0.6540.83
406_F417_K0.6540.83
126_L344_Q0.6520.83
213_P216_N0.6520.83
109_A112_R0.6510.83
220_V224_G0.6490.83
152_A315_H0.6490.83
85_L200_I0.6480.82
39_L63_L0.6480.82
141_A343_R0.6480.82
229_E232_R0.6470.82
237_D285_S0.6470.82
146_V320_V0.6440.82
148_L320_V0.6440.82
104_E230_K0.6430.82
129_T283_I0.6400.82
52_V69_V0.6370.81
154_V324_R0.6350.81
261_R284_T0.6350.81
221_A242_V0.6330.81
249_T308_S0.6320.81
409_E413_G0.6320.81
352_Q404_P0.6320.81
155_G243_D0.6310.81
89_M92_L0.6300.81
47_L53_R0.6280.80
396_K399_R0.6280.80
350_V354_H0.6270.80
361_V418_Y0.6260.80
33_Q37_E0.6260.80
413_G416_G0.6260.80
136_L139_P0.6230.80
201_D204_S0.6230.80
55_I255_V0.6210.80
356_D422_K0.6160.79
141_A348_L0.6160.79
225_L228_A0.6160.79
73_E76_I0.6150.79
85_L236_R0.6140.79
225_L242_V0.6140.79
166_N408_A0.6140.79
338_L365_L0.6130.79
138_C335_V0.6110.79
29_A40_V0.6100.78
165_R197_S0.6080.78
208_G217_R0.6080.78
226_T230_K0.6070.78
232_R291_I0.6030.78
384_S391_V0.6030.78
217_R229_E0.6020.78
55_I259_L0.6020.78
78_V81_G0.6010.77
127_L140_F0.6010.77
177_F187_G0.5990.77
152_A250_L0.5990.77
416_G420_S0.5990.77
175_S241_F0.5980.77
222_L252_G0.5970.77
32_V69_V0.5970.77
156_K243_D0.5970.77
196_D200_I0.5960.77
120_L123_S0.5950.77
126_L411_F0.5950.77
152_A314_A0.5950.77
33_Q36_N0.5940.77
131_I405_F0.5930.77
132_K417_K0.5920.76
30_L52_V0.5910.76
388_K392_A0.5900.76
161_M190_F0.5900.76
128_E414_S0.5890.76
165_R191_Y0.5880.76
37_E44_Q0.5880.76
353_E357_T0.5860.76
387_D395_R0.5860.76
53_R259_L0.5850.76
381_D384_S0.5850.76
305_T312_T0.5840.75
248_Y252_G0.5840.75
421_L425_I0.5840.75
250_L379_G0.5780.75
161_M207_Y0.5780.75
364_I367_R0.5780.75
152_A313_F0.5750.74
134_I159_N0.5710.74
129_T149_F0.5710.74
364_I390_V0.5700.74
95_P102_I0.5680.73
167_I237_D0.5670.73
80_V84_T0.5660.73
391_V395_R0.5660.73
414_S417_K0.5650.73
261_R271_T0.5640.73
364_I425_I0.5620.73
15_D46_Q0.5610.73
40_V53_R0.5600.72
368_Y398_Q0.5590.72
253_T308_S0.5580.72
111_H222_L0.5570.72
24_P71_D0.5550.72
95_P101_E0.5550.72
419_V422_K0.5540.72
314_A341_T0.5540.72
111_H278_V0.5520.71
311_T379_G0.5520.71
107_R389_L0.5510.71
21_D24_P0.5500.71
72_L75_P0.5490.71
192_H197_S0.5490.71
135_D166_N0.5490.71
121_S288_T0.5480.71
57_M222_L0.5480.71
149_F316_L0.5480.71
86_G97_D0.5480.71
208_G216_N0.5470.71
109_A226_T0.5470.71
29_A76_I0.5460.70
351_G419_V0.5440.70
34_N39_L0.5440.70
126_L355_Y0.5430.70
325_Q370_E0.5420.70
124_Q288_T0.5410.70
6_I9_V0.5410.70
35_G64_R0.5390.70
110_I294_V0.5380.69
400_F417_K0.5380.69
24_P52_V0.5380.69
151_G299_V0.5380.69
200_I205_L0.5370.69
39_L44_Q0.5370.69
372_K395_R0.5370.69
116_S120_L0.5360.69
218_L275_E0.5360.69
53_R148_L0.5360.69
301_A310_A0.5350.69
197_S205_L0.5350.69
346_D405_F0.5350.69
245_I279_L0.5320.69
176_V206_V0.5290.68
187_G209_Q0.5290.68
222_L259_L0.5290.68
148_L294_V0.5280.68
324_R328_S0.5270.68
13_V164_I0.5270.68
125_E288_T0.5260.68
194_M199_V0.5250.68
27_Y44_Q0.5250.68
112_R115_P0.5250.68
55_I379_G0.5250.68
153_G254_E0.5240.67
97_D102_I0.5230.67
228_A236_R0.5220.67
306_D310_A0.5220.67
83_A100_G0.5210.67
54_T69_V0.5210.67
83_A102_I0.5200.67
148_L322_L0.5200.67
10_I259_L0.5200.67
13_V222_L0.5200.67
112_R229_E0.5180.66
404_P408_A0.5170.66
29_A75_P0.5170.66
179_G182_E0.5170.66
96_V212_E0.5170.66
206_V223_T0.5160.66
395_R398_Q0.5160.66
337_P365_L0.5160.66
300_P305_T0.5150.66
314_A319_T0.5150.66
18_F24_P0.5150.66
57_M92_L0.5150.66
252_G255_V0.5130.66
157_T243_D0.5120.66
193_E226_T0.5110.65
34_N60_S0.5100.65
119_E124_Q0.5090.65
419_V423_D0.5090.65
161_M203_V0.5090.65
411_F414_S0.5090.65
326_I343_R0.5080.65
368_Y375_I0.5080.65
139_P341_T0.5080.65
232_R237_D0.5080.65
374_I377_I0.5080.65
384_S387_D0.5070.65
197_S200_I0.5070.65
82_K204_S0.5060.65
212_E269_Q0.5060.65
299_V305_T0.5050.65
25_R64_R0.5040.64
112_R117_Y0.5030.64
18_F164_I0.5030.64
346_D350_V0.5020.64
303_D306_D0.5020.64
212_E258_L0.5010.64
195_T201_D0.5000.64
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4q4lA 1 0.9457 100 0.102 Contact Map
1fx0B 3 0.9848 100 0.107 Contact Map
3oaaA 2 0.9739 100 0.11 Contact Map
2qe7A 1 0.9717 100 0.115 Contact Map
3vr4D 1 0.9478 100 0.13 Contact Map
2ck3A 1 0.9804 100 0.13 Contact Map
2r9vA 1 0.9783 100 0.131 Contact Map
1fx0A 1 0.9761 100 0.131 Contact Map
3gqbB 1 0.9478 100 0.133 Contact Map
2c61A 2 0.913 100 0.134 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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