GREMLIN Database
ATPF - ATP synthase subunit b
UniProt: P0ABA0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10103
Length: 156 (148)
Sequences: 4286 (3082)
Seq/√Len: 253.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
31_A35_K2.8361.00
49_R53_D2.3991.00
41_A45_A2.3991.00
74_V78_Q2.3581.00
34_E38_K2.2161.00
141_D144_A2.1951.00
48_E52_K2.1931.00
94_A98_R2.1381.00
89_E93_E2.0641.00
38_K42_D2.0471.00
42_D46_S1.9141.00
56_L60_S1.9021.00
93_E97_E1.8761.00
58_K62_T1.8051.00
99_T103_A1.7891.00
45_A49_R1.7611.00
110_E114_K1.6921.00
103_A107_A1.6521.00
59_A62_T1.6511.00
84_S88_D1.6251.00
98_R101_I1.6181.00
15_V19_L1.5651.00
37_Q41_A1.5631.00
113_R117_R1.5621.00
86_I89_E1.5601.00
59_A63_D1.5601.00
63_D67_K1.5571.00
60_S64_Q1.5401.00
102_V106_Q1.5271.00
19_L23_K1.5231.00
67_K71_E1.5171.00
77_E80_N1.5151.00
144_A147_D1.5061.00
88_D92_A1.5061.00
128_A132_A1.4841.00
71_E74_V1.4761.00
34_E37_Q1.4701.00
52_K56_L1.4661.00
147_D151_K1.4611.00
92_A96_Q1.4531.00
77_E81_K1.4371.00
67_K70_A1.3871.00
138_R144_A1.3711.00
81_K85_Q1.3671.00
28_P31_A1.3661.00
92_A95_E1.3591.00
45_A48_E1.3411.00
143_A146_S1.3251.00
19_L22_M1.3161.00
35_K39_E1.2951.00
95_E99_T1.2911.00
39_E43_G1.2651.00
55_D59_A1.2461.00
87_L90_A1.2461.00
78_Q82_R1.2171.00
96_Q99_T1.2141.00
61_A64_Q1.2111.00
52_K55_D1.2071.00
55_D58_K1.1821.00
128_A131_G1.1821.00
142_E146_S1.1801.00
46_S50_A1.1781.00
96_Q100_K1.1771.00
112_E115_R1.1601.00
87_L91_K1.1461.00
35_K38_K1.1461.00
64_Q67_K1.1321.00
105_A109_I1.1221.00
62_T66_K1.1081.00
63_D66_K1.1081.00
73_Q77_E1.1051.00
114_K118_E1.1021.00
51_H55_D1.1011.00
100_K104_Q1.0991.00
53_D56_L1.0821.00
119_E123_Q1.0801.00
111_A115_R1.0661.00
18_V22_M1.0551.00
101_I109_I1.0361.00
43_G51_H1.0241.00
85_Q89_E1.0141.00
93_E96_Q1.0141.00
86_I91_K1.0071.00
22_M27_P0.9941.00
84_S87_L0.9851.00
80_N84_S0.9841.00
54_L58_K0.9811.00
57_A60_S0.9781.00
139_S145_N0.9771.00
70_A73_Q0.9751.00
64_Q69_K0.9681.00
82_R85_Q0.9601.00
124_V128_A0.9591.00
60_S63_D0.9591.00
110_E113_R0.9561.00
146_S150_D0.9511.00
133_E137_E0.9501.00
7_I10_Q0.9471.00
6_T9_G0.9401.00
68_A72_A0.9371.00
109_I116_A0.9341.00
91_K95_E0.9281.00
49_R52_K0.9241.00
56_L59_A0.9201.00
104_Q107_A0.9191.00
89_E92_A0.9141.00
57_A61_A0.9101.00
106_Q110_E0.9071.00
86_I90_A0.8941.00
83_R87_L0.8881.00
81_K84_S0.8861.00
38_K41_A0.8841.00
143_A147_D0.8831.00
23_K27_P0.8641.00
22_M26_W0.8510.99
25_V28_P0.8460.99
107_A110_E0.8460.99
106_Q112_E0.8340.99
46_S49_R0.8310.99
70_A74_V0.8310.99
108_E112_E0.8260.99
98_R102_V0.8220.99
123_Q126_I0.8200.99
103_A106_Q0.8180.99
6_T10_Q0.8090.99
53_D58_K0.8080.99
118_E121_R0.8060.99
71_E75_I0.8040.99
126_I130_A0.7910.99
14_F18_V0.7900.99
76_I80_N0.7810.99
10_Q18_V0.7750.99
72_A76_I0.7720.99
21_C25_V0.7700.99
130_A134_K0.7660.99
140_V145_N0.7610.99
115_R119_E0.7550.99
115_R118_E0.7510.99
79_A83_R0.7480.99
66_K70_A0.7430.98
76_I79_A0.7390.98
10_Q13_A0.7360.98
120_L124_V0.7270.98
97_E100_K0.7270.98
47_A54_L0.7240.98
58_K61_A0.7230.98
30_M34_E0.7200.98
26_W30_M0.7160.98
138_R151_K0.7150.98
32_A35_K0.7120.98
140_V144_A0.7110.98
65_L69_K0.7100.98
22_M25_V0.7080.98
38_K46_S0.7060.98
83_R90_A0.6980.98
57_A62_T0.6980.98
97_E101_I0.6960.98
130_A133_E0.6890.98
78_Q81_K0.6830.97
107_A111_A0.6810.97
72_A75_I0.6810.97
30_M33_I0.6720.97
124_V127_L0.6710.97
9_G12_I0.6700.97
9_G13_A0.6640.97
90_A94_A0.6610.97
39_E42_D0.6560.97
102_V108_E0.6560.97
10_Q28_P0.6530.97
134_K137_E0.6520.97
13_A16_L0.6510.97
109_I120_L0.6500.97
85_Q88_D0.6310.96
134_K138_R0.6230.96
10_Q14_F0.6230.96
90_A93_E0.6200.95
13_A26_W0.6160.95
43_G46_S0.6160.95
90_A98_R0.6140.95
12_I16_L0.6120.95
48_E51_H0.6090.95
33_I37_Q0.6050.95
20_F24_Y0.6000.95
50_A53_D0.5970.94
40_I43_G0.5950.94
118_E122_K0.5940.94
117_R120_L0.5890.94
29_L33_I0.5890.94
104_Q108_E0.5860.94
50_A54_L0.5840.94
53_D57_A0.5770.93
108_E115_R0.5700.93
119_E122_K0.5690.93
114_K117_R0.5680.93
82_R125_A0.5670.93
17_F21_C0.5650.93
99_T102_V0.5610.92
18_V26_W0.5590.92
69_K72_A0.5510.92
52_K59_A0.5490.92
123_Q127_L0.5480.92
91_K97_E0.5440.91
88_D91_K0.5440.91
97_E102_V0.5390.91
40_I44_L0.5370.91
42_D49_R0.5350.91
78_Q85_Q0.5320.90
24_Y28_P0.5290.90
13_A27_P0.5280.90
21_C26_W0.5250.90
149_V153_V0.5210.89
44_L48_E0.5210.89
64_Q68_A0.5200.89
142_E145_N0.5130.89
73_Q76_I0.5110.88
131_G145_N0.5100.88
116_A127_L0.5100.88
127_L134_K0.5100.88
9_G16_L0.5050.88
132_A136_I0.5040.88
121_R125_A0.5000.87
145_N149_V0.5000.87
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1b9uA 1 0.2179 98.7 0.702 Contact Map
2dm9A 2 0.2115 98.4 0.724 Contact Map
2khkA 1 0.3397 98 0.755 Contact Map
1l2pA 1 0.391 97.8 0.767 Contact Map
3v6iA 1 0.7051 97.6 0.775 Contact Map
2clyA 1 0.6474 97.2 0.792 Contact Map
4efaG 1 0.609 92.1 0.849 Contact Map
4efaE 1 0.7372 91.8 0.85 Contact Map
3v6iB 1 0.6474 86.5 0.865 Contact Map
2kk7A 1 0.3333 37.2 0.906 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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