GREMLIN Database
YCHN - Protein YchN
UniProt: P0AB52 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12404
Length: 117 (113)
Sequences: 193 (121)
Seq/√Len: 11.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
3_K36_D3.8730.99
42_M80_T2.7360.92
38_R107_W2.6570.91
10_G17_S2.5940.89
55_P63_Q2.5070.88
50_L91_P2.3400.84
108_T114_V2.1580.78
59_Y64_M1.8870.68
9_N117_F1.7980.64
69_T114_V1.7720.63
69_T75_V1.7510.62
20_N59_Y1.7470.62
76_K107_W1.7060.60
18_L48_A1.7040.60
7_V111_A1.6880.59
9_N24_L1.6820.59
38_R110_S1.6630.58
8_A18_L1.6440.57
68_L73_V1.6250.56
53_Q85_R1.6090.55
79_K101_L1.6020.55
99_G103_E1.5770.54
108_T111_A1.5740.53
42_M45_A1.5550.53
11_A15_S1.5270.51
68_L116_T1.5170.51
11_A53_Q1.4830.49
87_I105_A1.4760.49
30_E63_Q1.4720.49
101_L108_T1.4060.45
7_V117_F1.3820.44
29_R87_I1.3730.44
99_G109_L1.3590.43
75_V95_G1.3440.42
43_S101_L1.3320.42
46_V77_L1.3310.42
9_N116_T1.3160.41
24_L117_F1.2920.40
5_V38_R1.2570.38
41_L104_L1.2360.37
12_P22_L1.2290.37
69_T93_I1.2060.36
52_G90_L1.2000.36
24_L83_D1.1830.35
65_L106_Q1.1690.34
8_A48_A1.1540.34
3_K18_L1.1450.33
28_L112_D1.1330.33
16_E85_R1.1180.32
15_S56_G1.1160.32
76_K110_S1.1160.32
16_E60_N1.1050.31
63_Q71_Q1.0920.31
16_E84_G1.0820.30
14_G53_Q1.0570.29
6_I15_S1.0470.29
19_F56_G1.0110.28
9_N58_G1.0100.28
7_V116_T1.0000.27
6_I45_A0.9960.27
85_R92_L0.9950.27
48_A70_A0.9880.27
59_Y104_L0.9870.27
54_K83_D0.9570.26
66_E71_Q0.9570.26
9_N115_L0.9530.25
24_L105_A0.9510.25
61_I64_M0.9450.25
56_G59_Y0.9400.25
3_K110_S0.9280.24
41_L64_M0.9250.24
3_K32_E0.9250.24
12_P17_S0.9180.24
8_A21_S0.9170.24
20_N56_G0.9130.24
53_Q84_G0.9070.24
72_N106_Q0.9060.24
77_L108_T0.9020.24
68_L99_G0.8910.23
11_A58_G0.8840.23
16_E53_Q0.8720.23
73_V116_T0.8680.22
27_A45_A0.8650.22
39_L52_G0.8530.22
37_L79_K0.8530.22
47_T50_L0.8490.22
33_S72_N0.8490.22
10_G16_E0.8400.21
91_P116_T0.8100.20
27_A75_V0.8030.20
49_G56_G0.8000.20
19_F51_R0.7910.20
72_N110_S0.7890.20
31_Q102_V0.7860.20
59_Y79_K0.7830.20
5_V82_T0.7770.19
38_R76_K0.7760.19
63_Q67_I0.7680.19
19_F79_K0.7680.19
30_E102_V0.7620.19
82_T96_V0.7480.19
26_I29_R0.7440.18
52_G98_I0.7420.18
57_E103_E0.7380.18
24_L116_T0.7340.18
32_E101_L0.7240.18
27_A101_L0.7230.18
4_I71_Q0.7060.17
57_E94_D0.7060.17
24_L64_M0.7050.17
41_L49_G0.6980.17
12_P15_S0.6870.17
8_A82_T0.6850.17
49_G77_L0.6810.17
51_R65_L0.6790.17
98_I108_T0.6790.17
9_N20_N0.6730.16
51_R83_D0.6690.16
10_G83_D0.6680.16
61_I75_V0.6670.16
74_P106_Q0.6630.16
8_A110_S0.6630.16
29_R69_T0.6600.16
37_L94_D0.6590.16
11_A14_G0.6530.16
85_R93_I0.6510.16
31_Q109_L0.6500.16
43_S98_I0.6470.16
11_A18_L0.6460.16
59_Y83_D0.6460.16
13_Y40_F0.6440.16
40_F86_G0.6390.16
39_L74_P0.6370.16
46_V61_I0.6350.15
50_L66_E0.6310.15
22_L41_L0.6290.15
6_I110_S0.6260.15
107_W110_S0.6230.15
3_K61_I0.6230.15
27_A105_A0.6210.15
10_G20_N0.6070.15
76_K103_E0.6020.15
36_D110_S0.5950.14
39_L97_E0.5830.14
63_Q66_E0.5790.14
94_D110_S0.5790.14
108_T115_L0.5780.14
5_V9_N0.5760.14
79_K98_I0.5760.14
75_V88_S0.5760.14
16_E95_G0.5650.14
19_F67_I0.5640.14
74_P103_E0.5630.14
10_G84_G0.5580.14
58_G117_F0.5460.13
55_P76_K0.5380.13
49_G59_Y0.5380.13
60_N85_R0.5370.13
42_M110_S0.5340.13
38_R45_A0.5320.13
38_R108_T0.5270.13
36_D115_L0.5240.13
36_D109_L0.5150.13
43_S50_L0.5120.13
11_A55_P0.5090.12
42_M68_L0.5050.12
18_L71_Q0.5040.12
21_S46_V0.5040.12
6_I103_E0.5020.12
5_V96_V0.5000.12
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2d1pA 2 0.9829 100 0.487 Contact Map
2d1pB 1 0.9829 100 0.507 Contact Map
2hy5A 2 0.9744 100 0.507 Contact Map
2hy5B 1 0.9829 100 0.51 Contact Map
1jx7A 5 1 100 0.518 Contact Map
3mc3A 3 0.8803 99.9 0.576 Contact Map
2hy5C 2 0.8547 99.9 0.602 Contact Map
3pnxA 4 0.9658 99.9 0.614 Contact Map
2qs7A 3 0.9573 99.8 0.625 Contact Map
2fb6A 3 0.906 99.8 0.655 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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