GREMLIN Database
YCEB - Uncharacterized lipoprotein YceB
UniProt: P0AB26 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11117
Length: 186 (177)
Sequences: 210 (132)
Seq/√Len: 9.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
159_G163_E4.6111.00
108_K112_F4.0200.99
12_V16_L3.3720.96
105_D112_F3.0260.93
44_K111_I2.9700.92
65_I73_V2.9010.91
93_T180_I2.4570.82
28_T175_V2.4100.81
105_D108_K2.3930.81
10_L17_V2.3330.79
72_K143_L2.2890.77
164_A168_K2.2250.75
25_Y118_V2.1240.72
35_S179_E2.1020.71
9_A13_S2.0450.69
11_I114_K1.9690.66
73_V165_M1.9010.63
86_L104_F1.8040.58
106_K166_A1.7850.58
33_N137_P1.7360.55
8_A11_I1.7260.55
7_A11_I1.7070.54
173_I180_I1.6940.54
38_K173_I1.6900.53
100_A163_E1.6880.53
165_M169_L1.6800.53
43_S180_I1.6740.53
145_N149_Q1.6600.52
52_A118_V1.6380.51
104_F156_R1.6290.51
46_I89_S1.6190.50
14_G26_T1.5990.49
72_K166_A1.5930.49
63_S138_Y1.5890.49
67_R109_G1.5600.47
8_A14_G1.5430.47
32_I58_L1.5420.47
116_M180_I1.5320.46
6_F12_V1.5040.45
27_I98_L1.5030.45
96_L110_A1.4930.44
137_P171_K1.4900.44
9_A149_Q1.4750.44
23_T182_I1.4530.43
43_S98_L1.4380.42
46_I61_L1.4370.42
100_A113_L1.4300.42
33_N109_G1.4150.41
58_L172_G1.3740.39
135_L149_Q1.3550.38
144_R150_Q1.3510.38
164_A169_L1.3300.37
109_G167_K1.3040.36
113_L158_D1.3010.36
83_M103_V1.2900.35
35_S156_R1.2790.35
94_M97_K1.2480.34
68_E100_A1.2320.33
57_V80_N1.2310.33
31_E95_K1.2270.33
87_F118_V1.2120.32
30_Q111_I1.1820.31
146_Y180_I1.1530.30
152_A156_R1.1510.30
94_M120_D1.1500.30
28_T162_G1.1410.30
35_S104_F1.1400.29
16_L19_C1.1330.29
15_L21_Q1.1300.29
42_F162_G1.1270.29
27_I104_F1.1180.29
25_Y39_H1.1160.29
22_L25_Y1.1150.29
50_G125_P1.1090.28
27_I43_S1.0950.28
51_V168_K1.0950.28
11_I139_L1.0910.28
87_F97_K1.0810.27
32_I168_K1.0790.27
19_C100_A1.0780.27
16_L105_D1.0630.27
71_N108_K1.0440.26
107_E112_F1.0320.26
94_M104_F1.0300.25
75_L110_A1.0280.25
31_E57_V1.0080.25
11_I75_L1.0080.25
7_A10_L1.0060.25
19_C25_Y0.9950.24
97_K121_A0.9850.24
116_M148_N0.9820.24
13_S179_E0.9820.24
47_G167_K0.9730.24
93_T107_E0.9640.23
33_N67_R0.9600.23
8_A132_M0.9540.23
106_K112_F0.9540.23
38_K117_E0.9490.23
112_F152_A0.9480.23
110_A152_A0.9370.22
111_I175_V0.9290.22
60_N78_D0.9270.22
100_A128_M0.9220.22
84_N95_K0.9180.22
34_Q93_T0.9170.22
103_V156_R0.9150.22
54_A128_M0.9050.21
67_R175_V0.9040.21
143_L148_N0.9010.21
44_K135_L0.8990.21
11_I17_V0.8970.21
78_D118_V0.8910.21
44_K50_G0.8860.21
57_V111_I0.8840.21
151_P180_I0.8820.21
156_R169_L0.8800.21
111_I135_L0.8770.21
54_A67_R0.8720.20
19_C22_L0.8720.20
32_I77_G0.8610.20
60_N89_S0.8550.20
175_V180_I0.8400.19
112_F134_T0.8340.19
28_T129_Q0.8320.19
23_T143_L0.8290.19
99_K173_I0.8290.19
118_V162_G0.8270.19
142_A172_G0.8210.19
18_G45_D0.8200.19
65_I167_K0.8190.19
28_T98_L0.8150.19
125_P171_K0.8120.19
22_L98_L0.8110.19
91_K123_V0.8090.19
17_V122_T0.8090.19
65_I122_T0.8080.19
70_P174_E0.8070.19
104_F118_V0.8020.18
18_G180_I0.7940.18
17_V175_V0.7890.18
175_V178_G0.7890.18
18_G111_I0.7880.18
158_D179_E0.7870.18
82_D106_K0.7870.18
7_A132_M0.7840.18
80_N133_Q0.7810.18
35_S68_E0.7660.17
92_A139_L0.7650.17
85_S140_N0.7650.17
81_L177_P0.7640.17
39_H146_Y0.7620.17
20_N152_A0.7600.17
140_N166_A0.7580.17
9_A12_V0.7520.17
36_L60_N0.7500.17
14_G108_K0.7480.17
35_S45_D0.7420.17
39_H152_A0.7420.17
36_L113_L0.7320.17
160_S171_K0.7300.17
34_Q50_G0.7270.16
40_N146_Y0.7270.16
92_A101_L0.7260.16
72_K144_R0.7240.16
10_L132_M0.7240.16
9_A20_N0.7220.16
10_L141_Q0.7150.16
74_T140_N0.7140.16
6_F11_I0.7130.16
13_S62_T0.7120.16
108_K132_M0.7010.16
18_G40_N0.7000.16
9_A57_V0.6970.16
165_M179_E0.6940.16
147_F182_I0.6930.16
25_Y59_T0.6910.16
81_L144_R0.6900.16
33_N63_S0.6800.15
60_N112_F0.6750.15
51_V115_E0.6740.15
77_G167_K0.6700.15
6_F30_Q0.6630.15
77_G113_L0.6620.15
107_E132_M0.6600.15
70_P158_D0.6580.15
15_L26_T0.6580.15
122_T150_Q0.6560.15
50_G65_I0.6560.15
12_V95_K0.6550.15
116_M173_I0.6540.15
14_G107_E0.6490.15
102_P153_Y0.6460.14
35_S159_G0.6450.14
127_K131_V0.6400.14
11_I60_N0.6370.14
61_L164_A0.6340.14
104_F117_E0.6330.14
83_M97_K0.6330.14
118_V131_V0.6320.14
115_E143_L0.6320.14
83_M104_F0.6300.14
101_L106_K0.6270.14
42_F90_Q0.6230.14
31_E47_G0.6230.14
10_L45_D0.6230.14
64_Q94_M0.6230.14
47_G137_P0.6200.14
156_R159_G0.6170.14
27_I180_I0.6170.14
12_V17_V0.6100.14
39_H52_A0.6080.14
9_A84_N0.6030.14
123_V170_A0.6020.14
27_I107_E0.6010.14
81_L121_A0.5980.13
10_L59_T0.5970.13
45_D60_N0.5960.13
33_N138_Y0.5880.13
9_A62_T0.5870.13
19_C111_I0.5860.13
26_T146_Y0.5850.13
71_N121_A0.5780.13
56_I128_M0.5730.13
62_T73_V0.5720.13
41_N120_D0.5690.13
62_T83_M0.5670.13
26_T61_L0.5660.13
45_D141_Q0.5650.13
147_F170_A0.5630.13
86_L147_F0.5610.13
9_A157_E0.5610.13
29_E167_K0.5600.13
73_V157_E0.5600.13
141_Q175_V0.5600.13
102_P151_P0.5580.13
45_D139_L0.5580.13
40_N52_A0.5560.13
57_V152_A0.5540.13
54_A176_K0.5520.12
83_M119_V0.5520.12
29_E35_S0.5510.12
26_T162_G0.5500.12
78_D95_K0.5480.12
14_G28_T0.5420.12
26_T122_T0.5410.12
104_F140_N0.5390.12
48_L126_E0.5380.12
131_V146_Y0.5370.12
9_A36_L0.5300.12
30_Q129_Q0.5290.12
67_R121_A0.5260.12
14_G21_Q0.5260.12
10_L13_S0.5260.12
14_G158_D0.5230.12
84_N146_Y0.5210.12
17_V30_Q0.5140.12
110_A178_G0.5140.12
10_L62_T0.5130.12
156_R173_I0.5120.12
49_P92_A0.5120.12
104_F143_L0.5120.12
77_G138_Y0.5110.12
26_T174_E0.5080.12
57_V119_V0.5070.12
38_K120_D0.5000.11
61_L96_L0.5000.11
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3l6iA 2 0.9247 100 0.281 Contact Map
2qgmA 1 0.7849 70 0.935 Contact Map
3zbiC 1 0.1398 67 0.937 Contact Map
3tlkA 1 0.6774 61.6 0.939 Contact Map
4n4rB 1 0.6559 61.2 0.939 Contact Map
3ekiA 1 0.8011 54.5 0.941 Contact Map
4peuA 1 0.6882 45.6 0.944 Contact Map
3qaxA 1 0.7634 32.7 0.949 Contact Map
4jg9A 2 0.5323 31 0.949 Contact Map
1xt8A 1 0.7688 30 0.95 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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