GREMLIN Database
YMBA - Uncharacterized lipoprotein YmbA
UniProt: P0AB10 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13719
Length: 187 (175)
Sequences: 1211 (929)
Seq/√Len: 70.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
91_L118_V3.9721.00
154_G170_G3.6921.00
152_L171_V3.6491.00
133_V175_E3.5301.00
87_L172_W3.4421.00
98_Q177_A3.2101.00
65_Q124_N2.9851.00
130_K153_E2.8391.00
160_G163_E2.7841.00
133_V171_V2.7491.00
95_L180_A2.6221.00
62_V165_V2.4771.00
152_L175_E2.4711.00
81_S89_N2.4111.00
158_Q163_E2.3861.00
46_L116_L2.3831.00
67_S70_K2.2991.00
131_V168_L2.2241.00
156_Q167_V2.2161.00
87_L120_V2.1691.00
116_L139_L2.1221.00
29_P169_A2.1031.00
125_G168_L2.1021.00
123_F168_L2.0651.00
94_N176_A2.0101.00
154_G174_Q2.0011.00
24_N77_N1.9891.00
118_V135_G1.9041.00
125_G164_M1.8551.00
46_L139_L1.7261.00
57_L168_L1.6971.00
164_M168_L1.6470.99
175_E179_I1.6410.99
47_W109_L1.6280.99
71_Y80_A1.5860.99
7_T10_A1.5800.99
25_Y75_N1.4990.99
154_G171_V1.4970.99
122_E134_S1.4740.99
81_S86_Q1.4720.99
68_D166_K1.4530.99
77_N161_Y1.4490.99
51_V118_V1.4300.98
124_N168_L1.3820.98
134_S151_R1.3750.98
74_A161_Y1.3680.98
125_G161_Y1.3510.98
123_F131_V1.3260.97
63_V73_I1.3040.97
131_V164_M1.2920.97
58_A82_P1.2560.96
64_Y74_A1.2510.96
135_G175_E1.2270.96
27_Q81_S1.1880.95
28_L83_L1.1810.95
56_Y86_Q1.1760.95
47_W115_T1.1740.95
52_T119_T1.1550.94
90_T169_A1.1540.94
33_S37_S1.1490.94
154_G167_V1.1280.94
26_Y165_V1.1220.93
55_D81_S1.1080.93
15_G106_S1.0970.93
119_T136_E1.0730.92
49_E107_Q1.0480.91
129_G168_L1.0400.91
83_L168_L1.0230.90
27_Q86_Q1.0120.89
172_W175_E0.9960.89
132_I153_E0.9890.88
47_W105_A0.9870.88
56_Y71_Y0.9870.88
29_P173_S0.9820.88
99_L180_A0.9820.88
58_A84_D0.9770.88
91_L169_A0.9700.87
57_L125_G0.9670.87
161_Y164_M0.9630.87
15_G143_G0.9620.87
70_K162_D0.9550.86
131_V140_N0.9350.85
47_W108_P0.9320.85
4_W8_I0.9280.85
152_L178_S0.9270.85
11_L140_N0.9250.85
143_G146_I0.9190.84
97_T176_A0.9180.84
99_L104_V0.9170.84
62_V104_V0.9150.84
14_A35_T0.9050.83
88_R92_V0.9000.83
68_D113_Q0.9000.83
12_W157_T0.8990.83
135_G150_F0.8970.83
9_A12_W0.8960.83
23_K59_G0.8950.83
61_G75_N0.8910.82
94_N169_A0.8900.82
174_Q177_A0.8860.82
163_E166_K0.8830.82
111_S155_V0.8820.82
92_V116_L0.8820.82
99_L137_W0.8770.81
91_L176_A0.8750.81
4_W40_S0.8720.81
34_G170_G0.8690.81
26_Y62_V0.8650.80
177_A181_Q0.8610.80
48_V92_V0.8520.79
134_S150_F0.8510.79
90_T173_S0.8480.79
49_E116_L0.8450.79
6_V9_A0.8440.79
28_L57_L0.8410.79
87_L135_G0.8360.78
120_V172_W0.8270.77
66_T70_K0.8230.77
66_T72_V0.8200.77
56_Y80_A0.8170.77
56_Y81_S0.8170.77
48_V95_L0.8170.77
47_W112_A0.8160.76
71_Y77_N0.8080.76
74_A125_G0.7950.75
146_I159_D0.7890.74
53_V87_L0.7870.74
150_F182_E0.7850.74
90_T172_W0.7850.74
90_T176_A0.7820.73
168_L172_W0.7810.73
114_D141_H0.7800.73
53_V84_D0.7750.73
89_N121_T0.7700.72
49_E115_T0.7690.72
74_A77_N0.7690.72
161_Y165_V0.7620.71
153_E180_A0.7600.71
45_L81_S0.7540.71
33_S141_H0.7520.70
90_T95_L0.7480.70
111_S114_D0.7370.69
61_G103_V0.7350.69
78_L149_P0.7330.68
65_Q69_V0.7290.68
46_L149_P0.7280.68
35_T174_Q0.7280.68
86_Q165_V0.7190.67
6_V10_A0.7140.66
15_G47_W0.7110.66
78_L113_Q0.7060.66
132_I151_R0.7040.65
57_L83_L0.7030.65
5_L8_I0.6990.65
121_T135_G0.6910.64
90_T94_N0.6900.64
46_L145_L0.6890.64
148_R178_S0.6840.63
114_D178_S0.6830.63
94_N173_S0.6820.63
171_V175_E0.6780.62
5_L37_S0.6760.62
31_V67_S0.6760.62
120_V135_G0.6750.62
27_Q56_Y0.6740.62
25_Y76_N0.6690.61
32_Q177_A0.6610.60
100_P116_L0.6600.60
4_W157_T0.6590.60
72_V81_S0.6580.60
25_Y62_V0.6580.60
93_A97_T0.6580.60
16_C79_W0.6500.59
81_S137_W0.6450.59
103_V148_R0.6430.58
133_V168_L0.6420.58
169_A173_S0.6400.58
69_V76_N0.6390.58
46_L113_Q0.6360.58
89_N92_V0.6340.57
33_S177_A0.6280.57
34_G122_E0.6250.56
137_W179_I0.6240.56
31_V58_A0.6210.56
89_N161_Y0.6120.55
116_L175_E0.6110.55
77_N84_D0.6100.54
77_N125_G0.6090.54
65_Q72_V0.6080.54
23_K78_L0.6070.54
133_V152_L0.6070.54
64_Y127_Y0.6060.54
32_Q36_Q0.6050.54
51_V137_W0.6020.53
13_L17_S0.6000.53
12_W31_V0.5970.53
150_F179_I0.5910.52
173_S177_A0.5880.52
32_Q176_A0.5880.52
66_T91_L0.5830.51
121_T149_P0.5810.51
170_G174_Q0.5800.51
98_Q179_I0.5800.51
63_V131_V0.5800.51
26_Y55_D0.5790.51
33_S40_S0.5780.51
13_L99_L0.5770.50
19_G59_G0.5770.50
13_L77_N0.5730.50
61_G77_N0.5730.50
118_V179_I0.5710.50
14_A110_G0.5710.50
83_L95_L0.5670.49
131_V152_L0.5640.49
138_L143_G0.5600.48
120_V146_I0.5590.48
80_A95_L0.5570.48
100_P103_V0.5550.48
28_L172_W0.5550.48
96_S126_R0.5520.47
30_V173_S0.5510.47
91_L106_S0.5510.47
23_K82_P0.5500.47
33_S116_L0.5460.47
48_V85_Q0.5450.47
11_L139_L0.5420.46
123_F133_V0.5420.46
97_T153_E0.5410.46
117_N140_N0.5380.46
156_Q168_L0.5370.46
70_K74_A0.5360.45
10_A35_T0.5340.45
74_A169_A0.5330.45
9_A15_G0.5320.45
29_P124_N0.5320.45
17_S48_V0.5320.45
9_A133_V0.5310.45
7_T84_D0.5300.45
35_T142_Q0.5270.44
25_Y61_G0.5270.44
156_Q160_G0.5230.44
28_L35_T0.5220.44
59_G73_I0.5210.44
19_G23_K0.5200.44
71_Y146_I0.5200.44
46_L61_G0.5190.43
95_L131_V0.5180.43
48_V91_L0.5160.43
4_W37_S0.5160.43
36_Q71_Y0.5140.43
122_E165_V0.5140.43
126_R129_G0.5100.42
102_W114_D0.5100.42
59_G82_P0.5090.42
53_V81_S0.5080.42
58_A71_Y0.5070.42
95_L106_S0.5070.42
65_Q126_R0.5070.42
48_V149_P0.5050.42
35_T128_D0.5030.42
54_P118_V0.5010.41
53_V82_P0.5000.41
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2iqiA 1 0.8663 100 0.291 Contact Map
4n4rB 1 0.6791 94.7 0.869 Contact Map
3zbiC 1 0.1497 80.3 0.902 Contact Map
4utoA 1 0.7807 70.3 0.909 Contact Map
1toaA 1 0.738 57.5 0.917 Contact Map
4kwyA 1 0.6203 38.9 0.925 Contact Map
4qflA 1 0.5134 32.9 0.928 Contact Map
3uorA 1 0.5668 30.7 0.929 Contact Map
4r2fA 1 0.5561 23.1 0.933 Contact Map
3te8A 2 0.5775 16.3 0.938 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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