GREMLIN Database
YCBJ - Uncharacterized protein YcbJ
UniProt: P0AB03 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13702
Length: 297 (256)
Sequences: 2020 (1530)
Seq/√Len: 95.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
196_I226_A3.8211.00
45_A91_L3.5461.00
60_K223_M3.2241.00
155_L158_T3.1111.00
229_E261_R2.8081.00
95_M208_D2.7841.00
111_E243_D2.7511.00
228_R252_A2.6661.00
155_L160_N2.5561.00
154_V157_T2.5201.00
269_D272_A2.5041.00
235_L245_L2.3231.00
155_L159_L2.2561.00
142_N151_H2.2541.00
79_M89_V2.2041.00
119_E250_Q2.1951.00
270_E285_F2.1491.00
236_M262_R2.0741.00
270_E288_A2.0701.00
126_R252_A1.9811.00
206_L218_V1.9661.00
147_W151_H1.9601.00
76_Y93_E1.9481.00
159_L275_V1.8941.00
134_G138_N1.8851.00
263_W291_S1.8681.00
142_N147_W1.8651.00
35_D42_P1.8461.00
147_W150_Q1.8451.00
140_Q151_H1.8391.00
63_M134_G1.8331.00
64_L72_M1.8211.00
74_T93_E1.7991.00
27_D30_L1.7931.00
58_A75_I1.7931.00
171_D286_D1.7681.00
148_Y152_V1.7441.00
114_K247_S1.7111.00
97_G218_V1.6941.00
142_N148_Y1.6841.00
145_P154_V1.6651.00
114_K122_L1.6591.00
122_L125_H1.6501.00
157_T160_N1.6491.00
263_W266_V1.6391.00
224_L230_Y1.6321.00
196_I230_Y1.6011.00
111_E247_S1.5941.00
97_G206_L1.5941.00
189_F227_P1.5871.00
112_Q119_E1.5721.00
148_Y151_H1.5361.00
23_N35_D1.5311.00
274_L285_F1.5051.00
25_K44_M1.5001.00
263_W288_A1.4891.00
65_A74_T1.4851.00
228_R254_V1.4721.00
114_K125_H1.4561.00
212_D215_L1.4511.00
174_I290_K1.4381.00
31_W48_F1.4261.00
113_L217_M1.4211.00
70_V120_A1.4140.99
176_F180_E1.4100.99
249_L254_V1.4020.99
63_M225_W1.3950.99
234_R237_D1.3950.99
234_R269_D1.3920.99
112_Q120_A1.3870.99
274_L282_R1.3800.99
114_K121_L1.3790.99
33_L44_M1.3730.99
140_Q147_W1.3700.99
236_M258_F1.3630.99
95_M216_A1.3510.99
235_L240_L1.3330.99
119_E251_R1.3280.99
52_G55_R1.3240.99
228_R253_P1.3150.99
186_F189_F1.3100.99
191_D227_P1.2810.99
28_T33_L1.2800.99
155_L163_N1.2770.99
25_K33_L1.2630.99
271_V285_F1.2620.99
111_E114_K1.2400.99
274_L279_R1.2400.99
257_S261_R1.2350.99
242_E246_W1.2260.99
25_K28_T1.2230.98
235_L244_L1.2200.98
113_L120_A1.2140.98
111_E119_E1.1980.98
155_L161_Q1.1930.98
231_E234_R1.1840.98
48_F54_A1.1730.98
205_M240_L1.1720.98
154_V158_T1.1650.98
71_R93_E1.1620.98
96_R209_S1.1610.98
28_T31_W1.1570.98
140_Q148_Y1.1520.98
59_W62_T1.1520.98
273_Q281_S1.1440.98
243_D246_W1.1380.98
282_R286_D1.1370.98
139_T151_H1.1210.97
38_G41_M1.1190.97
238_N281_S1.1140.97
133_V137_D1.1040.97
134_G137_D1.1010.97
154_V160_N1.0960.97
266_V269_D1.0920.97
178_T182_L1.0870.97
141_E151_H1.0860.97
63_M66_R1.0850.97
61_T220_P1.0850.97
168_T171_D1.0790.97
157_T161_Q1.0790.97
237_D269_D1.0780.97
232_L254_V1.0760.97
35_D94_R1.0570.96
208_D216_A1.0550.96
203_R273_Q1.0540.96
25_K94_R1.0510.96
247_S250_Q1.0500.96
229_E257_S1.0480.96
59_W136_V1.0480.96
122_L126_R1.0450.96
123_A251_R1.0380.96
279_R282_R1.0380.96
59_W135_A1.0360.96
270_E284_N1.0320.96
240_L244_L1.0320.96
111_E250_Q1.0320.96
208_D211_S1.0290.96
208_D212_D1.0280.96
147_W152_V1.0190.95
21_C24_E1.0160.95
159_L162_F1.0120.95
156_W160_N1.0120.95
144_W147_W1.0110.95
229_E255_A1.0070.95
122_L133_V0.9950.95
255_A261_R0.9900.95
286_D290_K0.9860.94
153_E157_T0.9860.94
21_C37_Q0.9840.94
30_L33_L0.9800.94
62_T74_T0.9800.94
288_A292_L0.9790.94
174_I286_D0.9730.94
77_G91_L0.9730.94
163_N172_K0.9680.94
243_D247_S0.9650.94
27_D33_L0.9630.94
145_P153_E0.9630.94
196_I224_L0.9590.94
280_F284_N0.9510.93
64_L67_S0.9430.93
113_L205_M0.9370.93
181_C184_A0.9370.93
145_P150_Q0.9350.93
63_M195_L0.9350.93
236_M266_V0.9170.92
160_N176_F0.9150.92
29_A33_L0.9040.91
143_F146_S0.8910.91
64_L124_W0.8890.91
230_Y269_D0.8890.91
235_L266_V0.8830.90
191_D228_R0.8810.90
247_S251_R0.8800.90
178_T183_P0.8790.90
273_Q277_T0.8730.90
283_R287_L0.8720.90
121_L125_H0.8710.90
24_E29_A0.8680.90
154_V159_L0.8650.90
177_R181_C0.8640.89
129_S132_C0.8630.89
159_L163_N0.8630.89
203_R238_N0.8560.89
61_T198_G0.8500.89
56_Q60_K0.8470.89
288_A291_S0.8450.88
36_S45_A0.8420.88
145_P151_H0.8400.88
237_D270_E0.8400.88
157_T179_R0.8370.88
279_R285_F0.8270.87
29_A34_Y0.8230.87
226_A265_Y0.8220.87
143_F154_V0.8190.87
120_A123_A0.8180.87
189_F228_R0.8070.86
171_D282_R0.8070.86
144_W148_Y0.7980.85
158_T161_Q0.7970.85
264_L292_L0.7960.85
27_D31_W0.7950.85
140_Q152_V0.7910.85
144_W265_Y0.7910.85
238_N273_Q0.7860.85
43_L76_Y0.7840.84
185_L188_G0.7800.84
261_R264_L0.7720.83
142_N152_V0.7720.83
102_A243_D0.7690.83
280_F283_R0.7680.83
233_F237_D0.7620.83
30_L48_F0.7620.83
198_G220_P0.7600.82
143_F147_W0.7580.82
37_Q40_P0.7550.82
121_L124_W0.7550.82
63_M135_A0.7530.82
26_A29_A0.7530.82
196_I223_M0.7500.82
186_F265_Y0.7500.82
62_T65_A0.7410.81
59_W63_M0.7400.81
71_R216_A0.7370.81
130_R137_D0.7350.80
57_L61_T0.7340.80
25_K31_W0.7340.80
148_Y227_P0.7330.80
271_V276_N0.7300.80
121_L133_V0.7290.80
65_A75_I0.7290.80
272_A276_N0.7240.79
26_A33_L0.7230.79
234_R266_V0.7200.79
174_I289_S0.7190.79
49_S70_V0.7150.78
286_D289_S0.7050.78
133_V138_N0.7050.78
25_K32_A0.7030.77
203_R281_S0.7030.77
268_W275_V0.7010.77
282_R285_F0.7010.77
269_D273_Q0.7000.77
148_Y265_Y0.6960.77
71_R208_D0.6960.77
131_G146_S0.6920.76
124_W127_Q0.6920.76
227_P265_Y0.6910.76
154_V161_Q0.6900.76
228_R249_L0.6900.76
226_A231_E0.6900.76
195_L223_M0.6890.76
157_T162_F0.6890.76
204_S219_G0.6830.75
239_S273_Q0.6800.75
156_W159_L0.6790.75
31_W34_Y0.6790.75
37_Q42_P0.6780.75
284_N287_L0.6720.74
260_W263_W0.6720.74
182_L185_L0.6680.74
167_L171_D0.6680.74
176_F179_R0.6640.73
45_A89_V0.6610.73
171_D279_R0.6610.73
84_H87_P0.6590.73
48_F53_K0.6560.72
71_R95_M0.6550.72
25_K29_A0.6550.72
224_L269_D0.6530.72
194_V228_R0.6520.72
126_R251_R0.6490.71
262_R266_V0.6480.71
58_A78_V0.6480.71
258_F262_R0.6470.71
132_C135_A0.6410.71
170_Q173_R0.6400.70
215_L225_W0.6390.70
201_C237_D0.6390.70
129_S133_V0.6380.70
142_N155_L0.6380.70
232_L253_P0.6290.69
128_D131_G0.6290.69
55_R78_V0.6260.69
25_K30_L0.6260.69
89_V268_W0.6260.69
246_W250_Q0.6250.69
92_L208_D0.6250.69
168_T172_K0.6230.68
227_P261_R0.6220.68
24_E32_A0.6210.68
24_E27_D0.6170.68
233_F266_V0.6150.67
149_R183_P0.6140.67
173_R176_F0.6140.67
34_Y47_S0.6140.67
44_M94_R0.6130.67
244_L265_Y0.6120.67
141_E147_W0.6100.67
41_M74_T0.6080.67
199_N219_G0.6070.66
53_K56_Q0.6060.66
122_L129_S0.6000.66
124_W131_G0.5990.65
151_H155_L0.5980.65
71_R212_D0.5960.65
64_L69_T0.5960.65
178_T264_L0.5930.65
226_A230_Y0.5880.64
63_M67_S0.5850.64
127_Q225_W0.5850.64
243_D250_Q0.5830.63
76_Y203_R0.5820.63
254_V258_F0.5810.63
139_T147_W0.5810.63
255_A259_I0.5800.63
200_F235_L0.5790.63
239_S278_G0.5790.63
229_E258_F0.5780.63
30_L152_V0.5770.62
270_E274_L0.5740.62
62_T66_R0.5740.62
124_W133_V0.5730.62
196_I231_E0.5680.61
160_N163_N0.5640.61
123_A131_G0.5620.60
25_K35_D0.5610.60
203_R237_D0.5590.60
269_D285_F0.5590.60
52_G88_D0.5580.60
285_F289_S0.5570.60
95_M215_L0.5550.60
160_N172_K0.5550.60
263_W270_E0.5480.59
285_F288_A0.5460.58
22_V280_F0.5440.58
284_N288_A0.5430.58
61_T238_N0.5410.58
77_G231_E0.5370.57
51_P78_V0.5370.57
225_W230_Y0.5370.57
140_Q268_W0.5360.57
287_L291_S0.5360.57
201_C277_T0.5350.57
137_D151_H0.5340.57
236_M259_I0.5340.57
148_Y155_L0.5340.57
195_L225_W0.5330.56
169_M172_K0.5330.56
120_A124_W0.5320.56
65_A72_M0.5320.56
144_W151_H0.5310.56
237_D273_Q0.5290.56
77_G162_F0.5260.56
232_L266_V0.5250.55
158_T162_F0.5250.55
260_W292_L0.5230.55
61_T90_L0.5210.55
182_L187_E0.5200.55
193_C227_P0.5190.55
186_F264_L0.5190.55
233_F238_N0.5180.54
275_V280_F0.5180.54
62_T78_V0.5170.54
120_A216_A0.5170.54
175_L285_F0.5170.54
128_D225_W0.5160.54
249_L253_P0.5130.54
60_K217_M0.5130.54
140_Q267_L0.5120.54
20_E39_N0.5100.53
166_G279_R0.5100.53
132_C193_C0.5090.53
73_P186_F0.5090.53
227_P255_A0.5080.53
283_R290_K0.5070.53
20_E40_P0.5060.53
102_A178_T0.5050.53
185_L189_F0.5050.53
178_T292_L0.5030.52
271_V277_T0.5010.52
140_Q155_L0.5010.52
230_Y274_L0.5010.52
237_D266_V0.5000.52
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3f7wA 1 0.9125 100 0.464 Contact Map
3jr1A 1 0.9293 100 0.538 Contact Map
3tdwA 1 0.9293 100 0.617 Contact Map
4dcaA 1 0.9226 100 0.625 Contact Map
3atsA 1 0.9461 100 0.634 Contact Map
3dxpA 2 0.9192 100 0.653 Contact Map
3w0oA 1 0.8889 100 0.655 Contact Map
3i1aA 1 0.9428 100 0.658 Contact Map
4orkA 1 0.9259 100 0.663 Contact Map
2q83A 1 0.9495 100 0.669 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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