GREMLIN Database
YBHP - Uncharacterized protein YbhP
UniProt: P0AAW1 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13672
Length: 253 (217)
Sequences: 12846 (9313)
Seq/√Len: 632.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
46_C173_A5.4041.00
11_K250_E5.1441.00
98_V125_C3.3061.00
46_C140_C2.8281.00
220_I249_A2.7491.00
13_L248_S2.5711.00
46_C138_V2.5201.00
126_R137_H2.5051.00
13_L42_A2.4011.00
105_E128_V2.3171.00
106_H126_R2.3091.00
47_L50_V2.2791.00
12_V171_L2.2431.00
196_I222_V2.1541.00
233_L248_S2.1431.00
128_V135_A2.1401.00
173_A220_I2.1321.00
194_D199_R2.0961.00
14_T48_Q2.0631.00
222_V251_I2.0451.00
43_D101_R2.0371.00
231_T248_S2.0321.00
124_Y137_H2.0191.00
169_P224_N1.9981.00
98_V140_C1.9941.00
137_H168_E1.9791.00
44_I138_V1.9331.00
48_Q140_C1.9271.00
14_T247_L1.9221.00
229_A250_E1.9041.00
36_A40_V1.8971.00
143_L154_L1.8911.00
126_R135_A1.8621.00
158_A162_N1.8101.00
100_S103_P1.8061.00
41_S101_R1.7881.00
103_P128_V1.7501.00
108_E124_Y1.6671.00
35_D38_R1.6651.00
104_I107_Y1.6381.00
170_V193_L1.6051.00
195_E216_R1.5611.00
13_L40_V1.5401.00
152_A156_M1.5251.00
126_R168_E1.5151.00
152_A155_A1.4801.00
11_K248_S1.4591.00
160_W164_L1.4521.00
32_E35_D1.4361.00
38_R77_M1.4171.00
141_V176_F1.4021.00
102_Y127_I1.4001.00
139_M161_V1.3981.00
46_C98_V1.3881.00
160_W163_E1.3811.00
143_L153_Q1.3611.00
171_L222_V1.3431.00
50_V97_A1.3241.00
222_V227_A1.3081.00
104_I127_I1.2981.00
138_V173_A1.2871.00
35_D39_T1.2821.00
220_I251_I1.2741.00
123_L140_C1.2721.00
189_V221_Y1.2631.00
197_F205_A1.2571.00
100_S104_I1.2511.00
42_A45_V1.2511.00
228_S250_E1.2401.00
157_L172_V1.2361.00
34_R38_R1.2301.00
124_Y139_M1.2261.00
139_M170_V1.2231.00
156_M159_E1.2161.00
179_W215_L1.2071.00
31_P35_D1.1961.00
71_E75_D1.1671.00
155_A187_L1.1661.00
81_F84_G1.1561.00
17_I47_L1.1411.00
47_L99_L1.1281.00
150_R154_L1.1251.00
105_E135_A1.1251.00
135_A168_E1.1161.00
155_A159_E1.1111.00
148_A152_A1.1091.00
122_V139_M1.0971.00
13_L37_V1.0941.00
151_Q155_A1.0941.00
13_L45_V1.0811.00
124_Y160_W1.0801.00
230_P233_L1.0791.00
141_V157_L1.0781.00
180_R219_R1.0741.00
137_H170_V1.0701.00
161_V193_L1.0631.00
201_H205_A1.0621.00
154_L158_A1.0581.00
158_A187_L1.0511.00
105_E126_R1.0491.00
186_P189_V1.0281.00
150_R153_Q1.0231.00
196_I230_P1.0191.00
162_N191_A1.0181.00
206_R209_P1.0181.00
20_G52_G1.0121.00
103_P106_H1.0111.00
128_V133_G1.0061.00
52_G56_V1.0051.00
80_D102_Y1.0051.00
171_L220_I1.0041.00
80_D103_P1.0011.00
72_F76_T0.9971.00
100_S127_I0.9931.00
140_C173_A0.9901.00
154_L178_D0.9881.00
195_E198_T0.9861.00
81_F99_L0.9811.00
228_S231_T0.9731.00
165_P224_N0.9671.00
178_D184_N0.9641.00
102_Y106_H0.9611.00
141_V172_V0.9541.00
172_V221_Y0.9531.00
44_I102_Y0.9531.00
113_S156_M0.9531.00
151_Q154_L0.9481.00
156_M160_W0.9451.00
231_T234_P0.9371.00
120_R123_L0.9341.00
199_R226_S0.9341.00
107_Y110_R0.9311.00
32_E241_L0.9301.00
29_I32_E0.9251.00
197_F230_P0.9241.00
234_P237_T0.9201.00
176_F221_Y0.9081.00
12_V44_I0.9011.00
229_A232_A0.8971.00
120_R127_I0.8921.00
84_G109_N0.8911.00
158_A191_A0.8791.00
172_V176_F0.8781.00
30_L34_R0.8771.00
89_Y118_E0.8761.00
45_V99_L0.8721.00
81_F85_R0.8711.00
15_I241_L0.8711.00
53_A56_V0.8691.00
98_V138_V0.8671.00
220_I247_L0.8601.00
139_M164_L0.8531.00
75_D78_W0.8521.00
122_V157_L0.8511.00
150_R178_D0.8451.00
222_V225_A0.8441.00
36_A233_L0.8421.00
104_I108_E0.8411.00
44_I127_I0.8401.00
17_I50_V0.8391.00
54_H57_H0.8361.00
137_H164_L0.8361.00
108_E160_W0.8301.00
71_E74_A0.8301.00
37_V45_V0.8281.00
73_L76_T0.8271.00
159_E162_N0.8191.00
134_K169_P0.8151.00
47_L97_A0.8141.00
143_L176_F0.8051.00
17_I20_G0.8041.00
194_D226_S0.8001.00
200_A227_A0.7961.00
96_N121_G0.7861.00
49_E175_D0.7831.00
12_V173_A0.7781.00
53_A91_E0.7781.00
176_F219_R0.7771.00
15_I33_L0.7761.00
180_R216_R0.7711.00
40_V248_S0.7701.00
79_S85_R0.7651.00
178_D182_K0.7621.00
185_H221_Y0.7571.00
216_R219_R0.7481.00
149_H153_Q0.7461.00
197_F200_A0.7441.00
138_V171_L0.7421.00
209_P245_A0.7411.00
208_F212_F0.7361.00
11_K41_S0.7351.00
119_K122_V0.7341.00
139_M160_W0.7291.00
122_V125_C0.7281.00
185_H219_R0.7251.00
72_F75_D0.7211.00
106_H109_N0.7201.00
109_N112_V0.7181.00
171_L251_I0.7151.00
96_N140_C0.7131.00
111_D114_V0.7121.00
148_A151_Q0.7021.00
205_A234_P0.6951.00
52_G57_H0.6881.00
33_L241_L0.6871.00
154_L184_N0.6871.00
153_Q157_L0.6861.00
35_D238_W0.6861.00
19_K51_M0.6851.00
186_P190_Q0.6781.00
82_A85_R0.6781.00
74_A81_F0.6771.00
240_H246_P0.6761.00
40_V233_L0.6751.00
209_P212_F0.6741.00
170_V223_K0.6721.00
37_V42_A0.6681.00
80_D100_S0.6661.00
231_T250_E0.6651.00
32_E238_W0.6621.00
122_V160_W0.6571.00
207_T212_F0.6571.00
40_V231_T0.6551.00
149_H152_A0.6501.00
144_G149_H0.6491.00
79_S83_Y0.6491.00
10_F251_I0.6381.00
36_A39_T0.6361.00
144_G153_Q0.6331.00
20_G30_L0.6231.00
127_I136_I0.6231.00
28_F32_E0.6221.00
110_R113_S0.6211.00
182_K185_H0.6211.00
76_T81_F0.6201.00
124_Y164_L0.6181.00
188_K221_Y0.6141.00
12_V251_I0.6141.00
15_I246_P0.6071.00
36_A241_L0.6051.00
207_T216_R0.6031.00
171_L225_A0.5991.00
44_I136_I0.5981.00
10_F102_Y0.5961.00
144_G147_E0.5951.00
11_K40_V0.5941.00
227_A230_P0.5911.00
123_L127_I0.5911.00
135_A169_P0.5911.00
128_V132_T0.5901.00
20_G53_A0.5891.00
15_I145_L0.5881.00
13_L246_P0.5871.00
199_R227_A0.5861.00
120_R125_C0.5841.00
187_L190_Q0.5821.00
28_F31_P0.5821.00
110_R122_V0.5801.00
121_G127_I0.5801.00
31_P34_R0.5791.00
53_A57_H0.5741.00
39_T233_L0.5741.00
136_I225_A0.5731.00
230_P234_P0.5721.00
79_S82_A0.5721.00
121_G124_Y0.5711.00
142_H175_D0.5711.00
42_A248_S0.5671.00
161_V172_V0.5651.00
14_T46_C0.5651.00
137_H167_G0.5641.00
34_R76_T0.5631.00
230_P249_A0.5621.00
31_P76_T0.5611.00
29_I34_R0.5611.00
12_V46_C0.5601.00
229_A233_L0.5591.00
178_D185_H0.5571.00
227_A232_A0.5531.00
196_I227_A0.5521.00
13_L36_A0.5521.00
44_I125_C0.5521.00
119_K123_L0.5521.00
78_W81_F0.5511.00
77_M80_D0.5491.00
229_A234_P0.5471.00
230_P237_T0.5471.00
80_D84_G0.5461.00
165_P168_E0.5441.00
105_E108_E0.5441.00
102_Y105_E0.5431.00
138_V220_I0.5421.00
197_F216_R0.5400.99
110_R160_W0.5380.99
206_R210_V0.5370.99
219_R222_V0.5370.99
193_L223_K0.5360.99
36_A246_P0.5350.99
75_D80_D0.5330.99
169_P223_K0.5320.99
128_V134_K0.5320.99
19_K22_T0.5320.99
33_L37_V0.5320.99
121_G125_C0.5280.99
82_A100_S0.5260.99
185_H189_V0.5240.99
124_Y127_I0.5200.99
74_A77_M0.5190.99
90_P94_H0.5170.99
74_A79_S0.5140.99
146_R150_R0.5140.99
54_H58_P0.5130.99
44_I100_S0.5110.99
74_A78_W0.5100.99
20_G51_M0.5080.99
169_P225_A0.5080.99
196_I249_A0.5070.99
32_E36_A0.5070.99
12_V138_V0.5050.99
194_D222_V0.5040.99
12_V249_A0.5030.99
120_R144_G0.5020.99
18_H22_T0.5010.99
200_A203_R0.5000.99
161_V170_V0.5000.99
176_F188_K0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4b8cD 1 0.332 100 0.248 Contact Map
3mprA 4 0.9328 100 0.282 Contact Map
3ngqA 1 0.9447 100 0.29 Contact Map
3g6sA 1 0.9209 100 0.294 Contact Map
4z0vA 1 0.9368 100 0.31 Contact Map
3l1wA 4 0.8933 100 0.315 Contact Map
3tebA 1 0.9407 100 0.326 Contact Map
4ruwA 1 0.9368 100 0.332 Contact Map
3wcxA 1 0.9091 100 0.339 Contact Map
3i41A 1 0.913 100 0.341 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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