GREMLIN Database
YBGJ - Uncharacterized protein YbgJ
UniProt: P0AAV4 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13306
Length: 218 (211)
Sequences: 2917 (2025)
Seq/√Len: 139.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
121_S212_P4.4821.00
89_E211_V4.3751.00
103_A113_E3.6531.00
94_Y120_H3.2681.00
151_R182_Q3.2671.00
119_L145_Q3.2091.00
118_E122_S3.0471.00
124_E207_S3.0021.00
86_R206_D2.8911.00
157_L176_A2.7891.00
115_Q118_E2.5191.00
128_W140_G2.4821.00
105_V116_V2.4361.00
109_C148_T2.2731.00
89_E209_R2.2641.00
90_I187_T2.2351.00
104_V151_R2.1721.00
173_Y179_G2.1061.00
127_V202_L2.0681.00
114_K118_E2.0431.00
40_M43_V1.9721.00
124_E209_R1.9611.00
112_S115_Q1.9171.00
68_I72_Q1.9061.00
91_P189_L1.8731.00
193_D196_R1.8131.00
87_F124_E1.7781.00
93_V98_G1.7661.00
57_L64_A1.7471.00
191_L202_L1.6881.00
10_G13_A1.6811.00
103_A107_A1.6721.00
119_L146_L1.6051.00
136_F171_G1.5851.00
95_G99_G1.5691.00
120_H170_T1.5491.00
93_V186_H1.5431.00
34_A38_V1.5341.00
15_V54_T1.5271.00
18_L33_L1.5211.00
164_G173_Y1.5031.00
87_F207_S1.4701.00
7_Y17_E1.4681.00
119_L143_P1.4671.00
106_A113_E1.4221.00
164_G179_G1.3951.00
190_S193_D1.3831.00
34_A46_A1.3641.00
139_L208_V1.3581.00
109_C116_V1.3461.00
58_R61_E1.3321.00
47_I56_I1.3291.00
13_A54_T1.3211.00
147_H168_P1.3171.00
188_S213_Q1.3121.00
104_V107_A1.3001.00
106_A109_C1.2821.00
159_P162_S1.2801.00
16_L33_L1.2731.00
93_V188_S1.2731.00
9_I54_T1.2701.00
92_V163_V1.2701.00
164_G182_Q1.2641.00
172_V191_L1.2631.00
64_A68_I1.2591.00
164_G171_G1.2541.00
5_R17_E1.2401.00
105_V148_T1.2311.00
133_Q177_T1.2311.00
87_F209_R1.2131.00
62_S67_A1.2021.00
125_Y170_T1.2001.00
91_P211_V1.1911.00
50_M169_Q1.1891.00
43_V55_V1.1861.00
142_L147_H1.1731.00
104_V108_H1.1710.99
151_R155_R1.1680.99
109_C146_L1.1650.99
127_V137_P1.1650.99
117_V121_S1.1560.99
70_R74_W1.1390.99
6_C75_W1.1310.99
115_Q119_L1.1300.99
18_L75_W1.1290.99
33_L53_I1.1290.99
114_K212_P1.1250.99
18_L30_I1.1250.99
165_I184_I1.1190.99
102_L106_A1.1110.99
198_E203_R1.1100.99
40_M70_R1.0970.99
85_S207_S1.0960.99
104_V182_Q1.0930.99
49_G52_N1.0860.99
106_A112_S1.0650.99
125_Y142_L1.0630.99
90_I189_L1.0580.99
63_L66_D1.0570.99
111_L119_L1.0560.99
66_D70_R1.0550.99
49_G129_F1.0550.99
123_V143_P1.0480.99
9_I15_V1.0150.99
91_P188_S1.0100.99
94_Y121_S1.0090.98
126_V207_S1.0050.98
173_Y177_T1.0020.98
94_Y170_T0.9900.98
35_Q38_V0.9890.98
88_I206_D0.9880.98
50_M128_W0.9800.98
90_I172_V0.9760.98
27_Q31_W0.9750.98
102_L113_E0.9720.98
137_P202_L0.9670.98
189_L201_L0.9650.98
14_V67_A0.9620.98
148_T182_Q0.9540.98
119_L122_S0.9530.98
162_S186_H0.9520.98
92_V185_G0.9500.98
120_H184_I0.9440.98
203_R206_D0.9430.98
15_V49_G0.9420.98
106_A116_V0.9410.98
96_G99_G0.9340.98
36_R39_D0.9340.98
174_P183_L0.9280.97
141_S171_G0.9230.97
162_S183_L0.9170.97
99_G102_L0.9100.97
36_R74_W0.8990.97
122_S143_P0.8980.97
73_R77_E0.8920.97
162_S176_A0.8870.97
105_V109_C0.8840.97
19_E26_S0.8820.96
42_N58_R0.8800.96
14_V68_I0.8770.96
132_F173_Y0.8740.96
36_R77_E0.8630.96
140_G169_Q0.8620.96
164_G183_L0.8590.96
43_V67_A0.8590.96
99_G183_L0.8570.96
105_V184_I0.8510.96
123_V141_S0.8380.95
7_Y15_V0.8330.95
17_E51_N0.8300.95
142_L166_G0.8290.95
106_A115_Q0.8270.95
90_I202_L0.8120.94
70_R73_R0.8120.94
196_R201_L0.8090.94
160_A190_S0.8090.94
30_I48_P0.8060.94
93_V214_K0.8010.94
144_E168_P0.8000.94
24_L126_V0.7970.94
177_T183_L0.7960.94
139_L210_F0.7950.94
43_V46_A0.7950.94
142_L146_L0.7920.94
132_F179_G0.7910.94
102_L117_V0.7900.94
167_G171_G0.7860.93
31_W34_A0.7790.93
34_A53_I0.7760.93
129_F204_P0.7750.93
143_P146_L0.7690.93
95_G98_G0.7620.92
64_A67_A0.7550.92
111_L116_V0.7530.92
38_V46_A0.7520.92
46_A55_V0.7520.92
173_Y183_L0.7510.92
94_Y125_Y0.7480.92
67_A71_L0.7480.92
159_P183_L0.7460.92
35_Q39_D0.7450.91
94_Y117_V0.7450.91
46_A53_I0.7360.91
167_G182_Q0.7320.91
105_V108_H0.7280.91
9_I13_A0.7200.90
93_V213_Q0.7200.90
44_V58_R0.7190.90
66_D69_E0.7150.90
127_V208_V0.7040.89
108_H182_Q0.7040.89
108_H149_P0.7030.89
124_E142_L0.6990.89
41_P61_E0.6960.88
170_T184_I0.6910.88
37_L55_V0.6910.88
65_L68_I0.6870.88
8_L64_A0.6840.88
45_E56_I0.6840.88
133_Q175_L0.6800.87
6_C68_I0.6790.87
179_G183_L0.6780.87
174_P177_T0.6730.87
95_G113_E0.6720.87
151_R156_L0.6700.87
128_W169_Q0.6690.86
109_C142_L0.6680.86
106_A111_L0.6680.86
159_P176_A0.6660.86
172_V210_F0.6590.86
88_I91_P0.6580.86
57_L60_P0.6560.85
192_F200_I0.6540.85
117_V212_P0.6530.85
125_Y136_F0.6530.85
26_S30_I0.6470.85
120_H210_F0.6460.84
95_G100_P0.6440.84
16_L71_L0.6430.84
74_W77_E0.6390.84
58_R62_S0.6380.84
155_R183_L0.6370.84
127_V206_D0.6360.84
12_T56_I0.6350.83
140_G168_P0.6350.83
16_L37_L0.6340.83
68_I71_L0.6330.83
19_E29_R0.6320.83
101_D136_F0.6290.83
55_V71_L0.6290.83
136_F139_L0.6260.83
57_L67_A0.6250.82
139_L171_G0.6240.82
144_E147_H0.6240.82
155_R173_Y0.6210.82
164_G177_T0.6180.82
134_P138_Y0.6170.82
130_L204_P0.6080.81
91_P187_T0.6030.80
117_V120_H0.6020.80
63_L67_A0.5950.79
69_E107_A0.5940.79
171_G174_P0.5940.79
150_R181_W0.5930.79
34_A48_P0.5880.79
147_H166_G0.5870.78
202_L208_V0.5860.78
113_E117_V0.5860.78
155_R164_G0.5860.78
9_I12_T0.5820.78
96_G113_E0.5810.78
15_V52_N0.5800.78
138_Y161_G0.5800.78
50_M129_F0.5780.77
166_G177_T0.5780.77
69_E77_E0.5770.77
129_F174_P0.5770.77
136_F174_P0.5760.77
101_D155_R0.5720.77
137_P191_L0.5710.76
86_R203_R0.5710.76
57_L62_S0.5690.76
125_Y165_I0.5690.76
127_V171_G0.5690.76
125_Y146_L0.5660.76
32_R78_S0.5650.76
155_R179_G0.5650.76
137_P206_D0.5640.76
13_A156_L0.5610.75
25_A46_A0.5570.75
15_V129_F0.5550.74
158_V175_L0.5540.74
6_C16_L0.5520.74
175_L200_I0.5510.74
111_L115_Q0.5510.74
59_N62_S0.5480.74
67_A70_R0.5470.73
66_D74_W0.5460.73
23_T26_S0.5450.73
19_E22_V0.5430.73
141_S146_L0.5410.73
83_P107_A0.5400.72
25_A107_A0.5360.72
132_F174_P0.5350.72
120_H125_Y0.5340.72
25_A97_A0.5340.72
77_E82_E0.5320.71
71_L75_W0.5320.71
174_P179_G0.5300.71
64_A71_L0.5290.71
51_N129_F0.5290.71
28_K80_A0.5260.71
50_M138_Y0.5240.70
63_L78_S0.5230.70
31_W35_Q0.5220.70
27_Q129_F0.5200.70
196_R199_P0.5200.70
8_L16_L0.5190.70
111_L145_Q0.5190.70
138_Y166_G0.5180.69
78_S83_P0.5180.69
31_W204_P0.5170.69
6_C14_V0.5150.69
20_P51_N0.5140.69
122_S209_R0.5140.69
83_P86_R0.5130.69
118_E190_S0.5120.68
169_Q192_F0.5120.68
49_G128_W0.5100.68
164_G174_P0.5090.68
69_E72_Q0.5090.68
30_I33_L0.5040.67
51_N133_Q0.5030.67
111_L146_L0.5030.67
129_F177_T0.5010.67
88_I189_L0.5000.67
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2phcB 1 0.9771 100 0.056 Contact Map
3mmlB 1 0.9358 100 0.125 Contact Map
3oepA 1 0.8945 100 0.133 Contact Map
3va7A 1 0.9771 100 0.159 Contact Map
2zp2A 1 0.5734 100 0.295 Contact Map
2kwaA 1 0.3945 99.6 0.78 Contact Map
4q2lA 1 0.2844 80.3 0.941 Contact Map
2ru9A 1 0.3119 39 0.955 Contact Map
3cjkB 1 0.3349 37.5 0.955 Contact Map
2g9oA 1 0.3165 29.4 0.958 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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