GREMLIN Database
YBGE - Uncharacterized protein YbgE
UniProt: P0AAV0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12395
Length: 97 (93)
Sequences: 123 (66)
Seq/√Len: 6.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
32_M55_M3.7810.94
60_A63_I2.4360.67
84_A92_L2.2960.62
6_A76_Q2.2520.61
55_M78_I2.2380.60
26_L30_G2.2340.60
13_D69_R2.1870.58
66_V69_R1.9740.50
38_R62_V1.7880.43
15_R24_M1.6970.40
33_F62_V1.6830.39
39_F84_A1.6550.38
21_S64_H1.6060.37
39_F92_L1.5940.36
76_Q87_V1.5480.35
48_I93_I1.5120.33
10_A96_F1.5110.33
27_L96_F1.4540.31
10_A74_L1.4010.30
75_W81_P1.3880.29
73_V76_Q1.3310.28
27_L30_G1.3280.27
17_L28_L1.3240.27
41_A49_W1.2940.26
22_F26_L1.2480.25
76_Q83_L1.2450.25
7_T27_L1.2390.25
35_D95_F1.2380.25
14_K22_F1.2280.25
5_I80_C1.2040.24
82_L91_G1.2010.24
25_A84_A1.1870.23
32_M87_V1.1840.23
53_L60_A1.1630.23
51_G58_V1.1550.23
15_R19_A1.1390.22
16_P20_L1.1380.22
38_R58_V1.1380.22
13_D16_P1.1300.22
43_T46_L1.1280.22
81_P84_A1.1250.22
25_A61_G1.1250.22
5_I54_L1.1090.21
75_W79_F1.0910.21
64_H90_V1.0890.21
47_E87_V1.0870.21
33_F46_L1.0850.21
27_L71_Q1.0780.21
7_T23_V1.0770.21
8_L21_S1.0720.20
71_Q80_C1.0710.20
41_A44_S1.0600.20
24_M39_F1.0450.20
52_L55_M1.0020.19
62_V95_F1.0020.19
6_A96_F1.0010.19
45_E73_V0.9930.19
18_R22_F0.9930.19
86_I89_I0.9820.18
55_M94_F0.9400.17
12_M17_L0.9400.17
50_H70_P0.9370.17
8_L64_H0.9330.17
33_F78_I0.9300.17
63_I85_D0.9220.17
32_M39_F0.9160.17
84_A91_G0.9150.17
12_M67_G0.9130.17
28_L61_G0.9010.17
78_I85_D0.8980.16
72_K87_V0.8820.16
23_V54_L0.8780.16
8_L30_G0.8740.16
39_F78_I0.8690.16
90_V93_I0.8430.15
32_M56_W0.8250.15
7_T96_F0.8240.15
67_G79_F0.8230.15
30_G57_A0.8200.15
53_L64_H0.8050.15
24_M96_F0.8030.15
31_C49_W0.8030.15
26_L86_I0.7990.14
21_S74_L0.7920.14
26_L92_L0.7830.14
53_L66_V0.7800.14
72_K89_I0.7780.14
26_L51_G0.7630.14
35_D56_W0.7630.14
10_A32_M0.7580.14
31_C62_V0.7570.14
30_G54_L0.7560.14
45_E48_I0.7560.14
8_L57_A0.7500.14
27_L66_V0.7440.13
21_S69_R0.7340.13
14_K91_G0.7330.13
12_M62_V0.7300.13
19_A57_A0.7210.13
31_C61_G0.7040.13
5_I55_M0.6970.13
30_G51_G0.6910.13
35_D52_L0.6810.12
5_I18_R0.6750.12
5_I42_K0.6720.12
7_T10_A0.6620.12
23_V74_L0.6610.12
32_M57_A0.6560.12
62_V67_G0.6560.12
6_A45_E0.6560.12
72_K83_L0.6450.12
5_I30_G0.6450.12
13_D21_S0.6410.12
45_E85_D0.6330.12
34_W63_I0.6310.12
24_M46_L0.6170.11
22_F25_A0.5960.11
14_K29_A0.5930.11
54_L57_A0.5890.11
32_M94_F0.5870.11
70_P80_C0.5850.11
58_V61_G0.5830.11
31_C46_L0.5800.11
80_C88_L0.5760.11
15_R96_F0.5650.11
76_Q90_V0.5640.11
16_P92_L0.5630.11
50_H83_L0.5570.10
30_G77_G0.5400.10
18_R49_W0.5350.10
46_L68_F0.5300.10
74_L77_G0.5230.10
74_L80_C0.5200.10
4_I41_A0.5130.10
25_A92_L0.5130.10
46_L61_G0.5070.10
11_V60_A0.5040.10
71_Q74_L0.5020.10
77_G86_I0.5010.10
19_A49_W0.5000.10
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3l1lA 2 0.9381 4.6 0.952 Contact Map
4xp4A 1 0.9794 4.5 0.952 Contact Map
3vouA 4 0.9072 4.1 0.953 Contact Map
4us3A 1 0.732 3.5 0.955 Contact Map
4djkA 2 0.9278 3.1 0.956 Contact Map
1ji8A 1 0.3402 2.7 0.957 Contact Map
4p02A 1 0.7732 2.6 0.957 Contact Map
1vsy5 1 0.9691 2.5 0.958 Contact Map
1fftB 1 0.6392 2.5 0.958 Contact Map
2rddB 1 0.1856 2.3 0.958 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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