GREMLIN Database
YLBF - Uncharacterized protein YlbF
UniProt: P0AAS5 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13626
Length: 271 (251)
Sequences: 286 (257)
Seq/√Len: 16.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
29_A41_T4.8991.00
24_G31_N4.2451.00
23_A31_N3.9871.00
20_W74_P3.2610.99
29_A43_H3.1250.99
31_N39_L3.0640.99
157_H161_K2.9910.98
53_G212_Y2.9270.98
179_A260_F2.5450.95
51_P216_A2.5120.95
172_T262_L2.4590.94
158_W169_H2.2350.91
178_L221_F2.1920.90
155_W173_L2.1490.89
249_G252_S2.1270.89
252_S259_G2.1270.89
249_G259_G2.1270.89
246_L254_A2.1240.89
43_H55_V2.1060.88
176_M263_G2.0970.88
174_S212_Y2.0970.88
212_Y222_A2.0420.86
174_S216_A2.0350.86
30_I42_L2.0100.86
53_G206_T1.9760.85
24_G39_L1.8490.80
20_W25_V1.8460.80
222_A256_T1.8350.80
249_G253_G1.8320.80
253_G259_G1.8320.80
29_A42_L1.7960.78
48_G222_A1.7740.77
166_T171_D1.7520.76
225_L260_F1.7450.76
31_N212_Y1.7420.76
161_K212_Y1.7390.76
212_Y221_F1.7270.75
252_S255_D1.7110.75
255_D259_G1.7110.75
249_G255_D1.7110.75
51_P177_L1.6940.74
53_G161_K1.6680.73
49_F97_L1.6120.70
245_L248_L1.5920.69
32_L42_L1.5540.67
51_P175_G1.4890.64
91_P97_L1.4770.63
213_L216_A1.4590.62
20_W32_L1.4390.61
41_T161_K1.4360.61
175_G213_L1.4200.60
23_A39_L1.3950.58
42_L161_K1.3810.58
41_T47_S1.3620.57
176_M216_A1.3560.56
12_S16_Y1.3370.55
53_G97_L1.3230.54
178_L225_L1.3150.54
171_D253_G1.3090.54
166_T253_G1.3090.54
29_A180_A1.3060.53
49_F250_H1.3010.53
63_A135_A1.2940.53
23_A207_A1.2910.52
72_E108_L1.2900.52
33_M207_A1.2750.52
164_G167_P1.2750.52
162_G167_P1.2750.52
26_W245_L1.2720.51
43_H256_T1.2600.51
31_N41_T1.2540.50
41_T52_G1.2510.50
60_Q225_L1.2480.50
212_Y251_T1.2440.50
211_S215_Y1.2330.49
263_G266_L1.2320.49
26_W31_N1.2280.49
160_G167_P1.2270.49
160_G164_G1.2270.49
24_G208_V1.2170.48
20_W221_F1.2100.48
251_T262_L1.2050.47
64_L242_I1.2040.47
20_W34_T1.1950.47
161_K169_H1.1940.47
28_R46_G1.1930.47
206_T212_Y1.1910.47
51_P213_L1.1910.47
215_Y221_F1.1890.47
43_H53_G1.1890.47
81_I101_P1.1890.47
41_T174_S1.1850.46
168_S255_D1.1810.46
174_S256_T1.1800.46
30_I41_T1.1630.45
56_L117_E1.1630.45
54_W194_F1.1580.45
29_A212_Y1.1560.45
29_A47_S1.1560.45
81_I174_S1.1460.44
106_Q138_R1.1410.44
162_G170_D1.1330.43
167_P170_D1.1330.43
164_G170_D1.1330.43
174_S213_L1.1280.43
137_L140_F1.1270.43
161_K206_T1.1190.43
164_G171_D1.1050.42
167_P171_D1.1050.42
162_G171_D1.1050.42
162_G166_T1.1050.42
174_S225_L1.1000.41
97_L223_S1.0980.41
165_L205_T1.0970.41
52_G211_S1.0930.41
79_Q105_P1.0840.41
173_L213_L1.0820.40
103_A208_V1.0820.40
52_G161_K1.0790.40
160_G170_D1.0790.40
42_L133_L1.0650.39
160_G166_T1.0510.39
160_G171_D1.0510.39
112_W200_N1.0490.39
168_S250_H1.0430.38
29_A172_T1.0420.38
31_N221_F1.0390.38
48_G262_L1.0180.37
256_T262_L1.0080.36
97_L208_V1.0030.36
22_L51_P0.9990.36
165_L171_D0.9980.36
41_T212_Y0.9810.35
36_S248_L0.9800.35
216_A251_T0.9780.35
167_P175_G0.9770.35
162_G175_G0.9770.35
164_G175_G0.9770.35
50_G250_H0.9740.35
50_G222_A0.9700.34
31_N208_V0.9650.34
25_V30_I0.9610.34
39_L212_Y0.9530.33
166_T170_D0.9520.33
122_F139_Q0.9460.33
43_H48_G0.9320.32
29_A52_G0.9260.32
30_I180_A0.9250.32
105_P108_L0.9190.32
139_Q198_S0.9170.32
47_S50_G0.9100.31
155_W198_S0.9080.31
178_L229_V0.9060.31
160_G175_G0.9040.31
164_G249_G0.9020.31
164_G259_G0.9020.31
164_G252_S0.9020.31
162_G252_S0.9020.31
162_G259_G0.9020.31
162_G249_G0.9020.31
167_P259_G0.9020.31
167_P252_S0.9020.31
167_P249_G0.9020.31
22_L25_V0.9020.31
165_L168_S0.8990.31
97_L204_V0.8960.31
71_N218_Q0.8950.30
251_T260_F0.8950.30
48_G256_T0.8880.30
245_L256_T0.8830.30
228_F245_L0.8710.29
83_L128_A0.8680.29
116_A120_G0.8640.29
50_G53_G0.8640.29
140_F206_T0.8590.29
159_L173_L0.8580.29
178_L196_A0.8570.29
245_L262_L0.8520.28
160_G259_G0.8500.28
160_G252_S0.8500.28
160_G249_G0.8500.28
22_L44_R0.8470.28
41_T53_G0.8450.28
164_G205_T0.8370.28
167_P205_T0.8370.28
162_G205_T0.8370.28
56_L61_F0.8370.28
155_W177_L0.8350.28
178_L215_Y0.8310.27
38_E198_S0.8290.27
37_G264_Q0.8270.27
102_P158_W0.8270.27
206_T245_L0.8240.27
29_A161_K0.8230.27
25_V70_G0.8230.27
89_K232_L0.8080.26
162_G209_S0.8010.26
164_G209_S0.8010.26
167_P209_S0.8010.26
158_W202_Q0.7970.26
155_W221_F0.7960.26
103_A139_Q0.7920.26
257_L260_F0.7870.25
29_A206_T0.7870.25
59_A105_P0.7860.25
170_D175_G0.7840.25
219_G245_L0.7750.25
100_T124_P0.7740.25
160_G205_T0.7710.25
146_A232_L0.7670.25
151_V179_A0.7630.24
46_G256_T0.7610.24
171_D175_G0.7570.24
166_T175_G0.7570.24
208_V246_L0.7560.24
22_L32_L0.7550.24
43_H169_H0.7530.24
170_D249_G0.7530.24
170_D252_S0.7530.24
170_D259_G0.7530.24
52_G223_S0.7490.24
54_W176_M0.7440.24
177_L221_F0.7430.24
208_V255_D0.7420.23
114_Q134_P0.7400.23
48_G172_T0.7340.23
28_R76_V0.7330.23
216_A225_L0.7310.23
77_V224_P0.7300.23
171_D252_S0.7260.23
171_D259_G0.7260.23
171_D249_G0.7260.23
166_T252_S0.7260.23
166_T249_G0.7260.23
166_T259_G0.7260.23
156_R204_V0.7230.23
97_L122_F0.7230.23
19_S99_I0.7210.23
168_S225_L0.7200.23
177_L222_A0.7200.23
160_G209_S0.7190.23
37_G132_P0.7190.23
154_D258_L0.7160.22
38_E236_K0.7130.22
29_A83_L0.7110.22
41_T250_H0.7070.22
18_Q113_M0.7020.22
122_F180_A0.6970.22
163_P257_L0.6960.22
76_V103_A0.6930.21
41_T44_R0.6920.21
43_H161_K0.6890.21
119_T142_H0.6870.21
24_G212_Y0.6850.21
155_W201_L0.6830.21
172_T180_A0.6830.21
59_A159_L0.6820.21
14_P29_A0.6790.21
168_S256_T0.6770.21
40_L52_G0.6770.21
41_T258_L0.6690.21
36_S143_C0.6680.21
243_D248_L0.6670.20
71_N154_D0.6630.20
170_D205_T0.6620.20
167_P253_G0.6580.20
164_G253_G0.6580.20
162_G253_G0.6580.20
221_F256_T0.6560.20
78_A168_S0.6560.20
71_N263_G0.6510.20
213_L222_A0.6480.20
161_K180_A0.6450.20
161_K248_L0.6420.20
112_W228_F0.6410.20
161_K172_T0.6400.19
105_P139_Q0.6390.19
52_G215_Y0.6370.19
166_T205_T0.6360.19
171_D205_T0.6360.19
56_L112_W0.6310.19
92_Q149_N0.6280.19
179_A263_G0.6250.19
28_R41_T0.6240.19
32_L173_L0.6230.19
38_E225_L0.6190.19
15_N230_H0.6180.19
26_W255_D0.6110.18
18_Q140_F0.6090.18
168_S172_T0.6060.18
223_S258_L0.6060.18
214_R225_L0.6030.18
54_W153_T0.6030.18
151_V176_M0.6020.18
146_A149_N0.6010.18
117_E230_H0.6010.18
110_A179_A0.6000.18
42_L184_G0.5980.18
160_G253_G0.5970.18
230_H239_A0.5960.18
24_G54_W0.5950.18
100_T145_Q0.5930.18
16_Y230_H0.5920.18
169_H264_Q0.5920.18
22_L154_D0.5920.18
94_Y148_L0.5910.18
242_I245_L0.5890.18
85_R138_R0.5860.18
52_G212_Y0.5840.18
170_D209_S0.5840.18
167_P255_D0.5830.17
162_G255_D0.5830.17
164_G255_D0.5830.17
175_G257_L0.5800.17
30_I161_K0.5800.17
241_A244_S0.5790.17
30_I75_Q0.5780.17
30_I159_L0.5770.17
26_W43_H0.5760.17
27_R100_T0.5760.17
62_D110_A0.5740.17
26_W169_H0.5720.17
145_Q177_L0.5720.17
49_F223_S0.5710.17
114_Q156_R0.5710.17
79_Q229_V0.5680.17
242_I257_L0.5680.17
79_Q82_R0.5670.17
30_I157_H0.5670.17
175_G252_S0.5660.17
175_G249_G0.5660.17
52_G97_L0.5660.17
175_G259_G0.5660.17
51_P176_M0.5660.17
23_A26_W0.5640.17
74_P105_P0.5630.17
128_A243_D0.5610.17
93_R178_L0.5600.17
212_Y256_T0.5600.17
29_A55_V0.5600.17
207_A210_V0.5590.17
12_S69_C0.5570.17
82_R94_Y0.5570.17
166_T209_S0.5560.17
171_D209_S0.5560.17
56_L78_A0.5540.17
53_G223_S0.5540.17
198_S206_T0.5540.17
193_P243_D0.5540.17
32_L147_A0.5520.16
188_A242_I0.5520.16
71_N200_N0.5510.16
52_G176_M0.5460.16
127_L232_L0.5410.16
108_L154_D0.5380.16
28_R31_N0.5370.16
190_S258_L0.5360.16
56_L64_L0.5360.16
81_I151_V0.5350.16
41_T180_A0.5330.16
43_H47_S0.5330.16
76_V260_F0.5310.16
213_L260_F0.5290.16
93_R244_S0.5290.16
24_G161_K0.5240.16
69_C83_L0.5150.15
27_R32_L0.5130.15
154_D251_T0.5130.15
206_T242_I0.5120.15
98_R145_Q0.5120.15
160_G255_D0.5110.15
103_A110_A0.5100.15
12_S17_R0.5100.15
25_V71_N0.5090.15
202_Q245_L0.5000.15
119_T122_F0.5000.15
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2od5A 4 0.2989 10.8 0.96 Contact Map
1eoqA 1 0.2694 9.6 0.961 Contact Map
1jalA 1 0.2768 4.4 0.967 Contact Map
2zbvA 3 0.2694 4.1 0.967 Contact Map
2r7dA 1 0.2731 4 0.967 Contact Map
2qcpX 1 0.2878 3.9 0.968 Contact Map
2qyvA 2 0.417 3.7 0.968 Contact Map
2r3sA 4 0.5904 3.4 0.968 Contact Map
1rqpA 4 0.2694 3.4 0.968 Contact Map
2gprA 1 0.4207 3.3 0.969 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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