GREMLIN Database
YKGJ - Uncharacterized protein YkgJ
UniProt: P0AAL9 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14323
Length: 109 (100)
Sequences: 294 (187)
Seq/√Len: 18.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
39_E52_N4.9321.00
64_T67_K3.6391.00
28_D35_A3.5591.00
84_F96_A2.9120.99
87_S98_N2.6270.98
26_A46_R2.5900.97
16_F103_K2.4840.97
62_A72_T2.3990.96
52_N56_P2.0790.91
12_A15_A2.0300.90
28_D46_R2.0130.90
62_A70_C1.8950.87
87_S94_N1.8720.86
27_D35_A1.7530.82
33_I73_I1.6200.76
23_W26_A1.5590.73
25_E79_S1.5180.71
7_C11_G1.4970.70
63_G66_G1.4710.69
8_M68_N1.4350.67
96_A99_R1.3970.65
84_F94_N1.3840.64
56_P80_T1.3690.63
20_S47_C1.3210.60
102_A108_P1.2840.58
63_G74_Y1.2810.58
19_V51_T1.2630.57
15_A49_S1.2600.57
40_Q43_P1.2430.55
12_A19_V1.2270.55
24_A94_N1.2140.54
8_M98_N1.1970.53
10_C14_C1.1940.52
10_C13_C1.1940.52
79_S100_A1.1700.51
23_W38_T1.1460.49
23_W46_R1.1220.48
5_N69_A1.1160.48
63_G69_A1.1130.47
9_T104_Y1.0780.45
26_A35_A1.0640.44
23_W47_C1.0620.44
11_G14_C1.0620.44
31_G37_L1.0270.42
65_P104_Y0.9870.40
75_K84_F0.9810.39
22_Y47_C0.9790.39
42_S46_R0.9740.39
39_E53_Q0.9710.39
98_N108_P0.9690.39
83_E95_E0.9540.38
20_S23_W0.9510.37
39_E47_C0.9480.37
14_C18_R0.9180.36
13_C18_R0.9180.36
10_C18_R0.9180.36
5_N22_Y0.9170.35
37_L72_T0.9050.35
13_C19_V0.8960.34
10_C19_V0.8960.34
14_C19_V0.8960.34
37_L59_I0.8700.33
24_A28_D0.8670.33
95_E99_R0.8660.33
5_N8_M0.8480.32
22_Y38_T0.8470.32
33_I84_F0.8360.31
100_A104_Y0.8310.31
24_A95_E0.8290.31
35_A46_R0.8290.31
11_G19_V0.8220.30
26_A47_C0.8030.29
4_L9_T0.8010.29
7_C13_C0.7940.29
7_C14_C0.7940.29
7_C10_C0.7940.29
85_A94_N0.7800.28
24_A29_A0.7760.28
5_N94_N0.7680.27
5_N84_F0.7630.27
94_N98_N0.7600.27
79_S86_M0.7580.27
53_Q76_N0.7560.27
5_N87_S0.7500.27
42_S45_H0.7480.26
42_S83_E0.7460.26
11_G18_R0.7410.26
20_S24_A0.7350.26
15_A104_Y0.7300.26
22_Y52_N0.7230.25
59_I76_N0.7190.25
8_M86_M0.7070.25
37_L45_H0.7060.24
37_L73_I0.7030.24
43_P59_I0.7020.24
80_T103_K0.6950.24
37_L75_K0.6880.24
12_A100_A0.6860.24
15_A66_G0.6850.23
55_N99_R0.6760.23
16_F54_K0.6680.23
30_G40_Q0.6660.23
40_Q47_C0.6540.22
70_C74_Y0.6510.22
20_S94_N0.6500.22
49_S86_M0.6450.22
24_A47_C0.6440.22
78_S82_R0.6410.22
49_S59_I0.6390.21
35_A65_P0.6370.21
27_D46_R0.6310.21
43_P46_R0.6310.21
65_P72_T0.6300.21
63_G80_T0.6260.21
31_G94_N0.6160.21
51_T59_I0.6150.20
16_F108_P0.6120.20
26_A30_G0.6090.20
38_T46_R0.6040.20
15_A65_P0.6010.20
15_A63_G0.6000.20
67_K105_G0.6000.20
19_V43_P0.5980.20
27_D31_G0.5980.20
23_W29_A0.5970.20
59_I103_K0.5910.20
42_S52_N0.5890.19
17_F79_S0.5850.19
51_T71_C0.5840.19
38_T78_S0.5840.19
22_Y94_N0.5780.19
18_R25_E0.5760.19
45_H96_A0.5740.19
26_A39_E0.5690.19
23_W87_S0.5650.19
36_R106_L0.5630.18
6_P69_A0.5620.18
36_R103_K0.5580.18
51_T62_A0.5580.18
65_P98_N0.5560.18
8_M104_Y0.5480.18
17_F63_G0.5460.18
27_D36_R0.5250.17
37_L107_T0.5170.17
30_G75_K0.5120.17
54_K87_S0.5110.17
33_I60_A0.5040.16
20_S69_A0.5020.16
20_S96_A0.5000.16
56_P104_Y0.5000.16
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3plvC 1 0.1743 17.9 0.947 Contact Map
3ec1A 1 0.1835 7.7 0.955 Contact Map
2bs2B 1 0.3486 6.8 0.956 Contact Map
1kf6B 1 0.422 3.8 0.961 Contact Map
1gteA 4 0.6147 3 0.963 Contact Map
3h2yA 1 0.1927 2.9 0.963 Contact Map
2gfiA 4 0.3394 2.5 0.965 Contact Map
3e9vA 1 0.5229 2.3 0.966 Contact Map
3i9v9 1 0.6972 2.2 0.966 Contact Map
3dwbA 1 0.3853 2.2 0.966 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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