FDNH - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

FDNH - Formate dehydrogenase, nitrate-inducible, iron-sulfur subunit

UniProt:	P0AAJ3	Sequences: MAMETQDIIKRSATNSITPPSQVRDYKAEVAKLIDVSTCIGCKACQVACSEWNDIRDEVGHCVGVYDNPADLSAKSWTVMRFSETEQNGKLEWLIRKDGCMHCEDPGCLKACPSAGAIIQYANGIVDFQSENCIGCGYCIAGCPFNIPRLNKEDNRVYKCTLCVDRVSVGQEPACVKTCPTGAIHFGTKKEMLELAEQRVAKLKARGYEHAGVYNPEGVGGTHVMYVLHHADQPELYHGLPKDPKIDTSVSLWKGALKPLAAAGFIATFAGLIFHYIGIGPNKEVDDDEEDHHE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11228
Length:	294 (254)
Sequences:	855 (484)
Seq/√Len:	30.3

ECOLI - FDNH FDOH HYBA NRFC YDHX YNFG DMSB
HALSA - DMSB
SULSO - Q97V38 Q97XX9 Q97V75

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
176_V	184_I	5.083	1.00
197_E	216_P	3.268	1.00
117_A	120_Q	3.228	1.00
235_E	242_K	3.107	1.00
30_V	188_T	3.064	1.00
189_K	193_L	3.060	1.00
185_H	195_L	2.942	1.00
46_Q	69_P	2.892	1.00
195_L	198_Q	2.807	1.00
78_T	97_K	2.685	1.00
116_G	120_Q	2.632	1.00
107_G	142_G	2.564	1.00
219_V	222_T	2.545	0.99
52_W	165_D	2.494	0.99
31_A	192_M	2.442	0.99
137_G	150_L	2.283	0.99
150_L	157_V	2.278	0.99
197_E	213_V	2.246	0.99
164_V	168_S	2.220	0.99
32_K	224_V	2.212	0.99
71_D	149_R	2.204	0.98
106_P	120_Q	2.137	0.98
40_I	181_T	2.134	0.98
104_E	223_H	2.054	0.98
52_W	174_A	2.026	0.97
34_I	224_V	1.986	0.97
33_L	225_M	1.963	0.97
172_E	177_K	1.924	0.96
33_L	227_V	1.909	0.96
194_E	197_E	1.888	0.96
112_C	133_C	1.872	0.96
28_A	190_K	1.869	0.96
23_V	26_Y	1.869	0.96
112_C	139_C	1.859	0.96
133_C	139_C	1.852	0.96
228_L	234_P	1.825	0.95
194_E	198_Q	1.816	0.95
29_E	223_H	1.763	0.94
53_N	161_T	1.761	0.94
37_S	231_A	1.748	0.94
276_Y	280_G	1.723	0.93
198_Q	201_A	1.693	0.93
105_D	110_K	1.682	0.93
275_H	280_G	1.641	0.92
215_N	218_G	1.636	0.91
203_L	207_G	1.631	0.91
267_A	270_A	1.619	0.91
193_L	216_P	1.606	0.91
257_L	271_G	1.605	0.91
192_M	225_M	1.601	0.91
42_C	45_C	1.593	0.90
39_C	45_C	1.593	0.90
39_C	42_C	1.593	0.90
109_L	118_I	1.576	0.90
57_D	76_S	1.562	0.89
193_L	213_V	1.551	0.89
262_A	266_I	1.503	0.87
58_E	73_S	1.495	0.87
198_Q	202_K	1.493	0.87
188_T	191_E	1.478	0.87
189_K	225_M	1.463	0.86
260_L	266_I	1.456	0.86
24_R	27_K	1.454	0.86
113_P	134_I	1.433	0.85
77_W	158_Y	1.410	0.84
165_D	174_A	1.409	0.84
52_W	166_R	1.400	0.83
187_G	192_M	1.399	0.83
271_G	274_F	1.397	0.83
31_A	162_L	1.393	0.83
121_Y	127_D	1.365	0.82
29_E	104_E	1.353	0.81
38_T	182_G	1.348	0.81
34_I	162_L	1.339	0.81
129_Q	132_N	1.334	0.80
204_K	207_G	1.325	0.80
267_A	271_G	1.297	0.78
28_A	188_T	1.283	0.78
130_S	141_A	1.267	0.77
99_G	224_V	1.264	0.76
116_G	119_I	1.255	0.76
137_G	140_I	1.250	0.76
145_F	222_T	1.250	0.76
257_L	260_L	1.235	0.75
166_R	177_K	1.233	0.75
261_A	267_A	1.227	0.74
30_V	186_F	1.224	0.74
57_D	60_G	1.205	0.73
32_K	184_I	1.203	0.73
172_E	182_G	1.202	0.73
195_L	201_A	1.176	0.71
105_D	273_I	1.165	0.70
40_I	44_A	1.159	0.70
266_I	269_F	1.151	0.69
193_L	197_E	1.148	0.69
151_N	154_D	1.142	0.69
171_Q	177_K	1.141	0.69
34_I	226_Y	1.132	0.68
205_A	209_E	1.121	0.67
166_R	171_Q	1.121	0.67
256_A	266_I	1.119	0.67
46_Q	68_N	1.119	0.67
146_N	184_I	1.113	0.67
116_G	123_N	1.113	0.67
78_T	99_G	1.111	0.67
34_I	99_G	1.102	0.66
125_I	167_V	1.098	0.66
112_C	135_G	1.093	0.65
200_V	227_V	1.074	0.64
269_F	278_G	1.067	0.63
33_L	192_M	1.063	0.63
135_G	139_C	1.058	0.63
197_E	201_A	1.048	0.62
80_M	125_I	1.047	0.62
146_N	176_V	1.040	0.61
189_K	222_T	1.029	0.61
172_E	272_L	1.026	0.60
182_G	225_M	1.024	0.60
200_V	203_L	1.021	0.60
68_N	82_F	1.013	0.59
154_D	158_Y	1.008	0.59
265_F	269_F	1.005	0.59
213_V	216_P	1.003	0.59
36_V	226_Y	1.003	0.59
128_F	148_P	0.999	0.58
173_P	176_V	0.995	0.58
203_L	211_A	0.989	0.57
128_F	157_V	0.986	0.57
257_L	263_A	0.986	0.57
212_G	231_A	0.980	0.57
104_E	119_I	0.975	0.56
24_R	28_A	0.973	0.56
270_A	273_I	0.964	0.56
36_V	94_L	0.955	0.55
72_L	178_T	0.945	0.54
198_Q	248_T	0.937	0.53
193_L	225_M	0.933	0.53
255_G	259_P	0.932	0.53
106_P	123_N	0.923	0.52
80_M	95_I	0.922	0.52
120_Q	123_N	0.922	0.52
117_A	121_Y	0.918	0.52
234_P	239_G	0.913	0.51
43_K	67_D	0.912	0.51
27_K	88_N	0.906	0.51
176_V	183_A	0.903	0.51
71_D	81_R	0.902	0.51
44_A	178_T	0.900	0.50
87_Q	90_K	0.890	0.50
114_S	136_C	0.890	0.50
38_T	185_H	0.886	0.49
193_L	215_N	0.885	0.49
71_D	148_P	0.882	0.49
23_V	27_K	0.881	0.49
47_V	178_T	0.876	0.49
32_K	176_V	0.871	0.48
260_L	263_A	0.871	0.48
47_V	52_W	0.870	0.48
52_W	82_F	0.869	0.48
77_W	151_N	0.857	0.47
262_A	269_F	0.857	0.47
156_R	252_L	0.857	0.47
121_Y	125_I	0.856	0.47
67_D	79_V	0.855	0.47
34_I	134_I	0.854	0.47
117_A	132_N	0.854	0.47
126_V	165_D	0.853	0.47
218_G	221_G	0.853	0.47
256_A	259_P	0.850	0.46
84_E	165_D	0.849	0.46
74_A	153_E	0.849	0.46
136_C	142_G	0.846	0.46
272_L	279_I	0.844	0.46
198_Q	269_F	0.844	0.46
89_G	233_Q	0.841	0.46
254_K	259_P	0.841	0.46
43_K	46_Q	0.839	0.46
106_P	148_P	0.838	0.45
250_V	253_W	0.834	0.45
118_I	128_F	0.830	0.45
113_P	133_C	0.819	0.44
35_D	199_R	0.817	0.44
207_G	211_A	0.811	0.43
260_L	279_I	0.799	0.42
259_P	273_I	0.797	0.42
65_V	68_N	0.797	0.42
189_K	216_P	0.795	0.42
119_I	129_Q	0.792	0.42
140_I	157_V	0.790	0.42
30_V	125_I	0.788	0.42
44_A	51_E	0.787	0.41
64_G	72_L	0.786	0.41
201_A	206_R	0.783	0.41
235_E	241_P	0.780	0.41
113_P	139_C	0.780	0.41
51_E	177_K	0.775	0.41
31_A	188_T	0.774	0.40
167_V	276_Y	0.766	0.40
213_V	227_V	0.766	0.40
215_N	220_G	0.762	0.40
97_K	226_Y	0.762	0.40
234_P	237_Y	0.762	0.40
172_E	176_V	0.761	0.39
265_F	271_G	0.761	0.39
97_K	224_V	0.755	0.39
142_G	224_V	0.754	0.39
241_P	244_P	0.751	0.39
86_E	90_K	0.746	0.38
60_G	69_P	0.745	0.38
35_D	42_C	0.745	0.38
35_D	45_C	0.745	0.38
35_D	39_C	0.745	0.38
54_D	168_S	0.745	0.38
162_L	167_V	0.743	0.38
138_Y	142_G	0.739	0.38
43_K	69_P	0.739	0.38
58_E	142_G	0.733	0.37
90_K	208_Y	0.731	0.37
61_H	264_G	0.730	0.37
273_I	276_Y	0.728	0.37
156_R	206_R	0.727	0.37
257_L	261_A	0.725	0.37
202_K	205_A	0.722	0.37
211_A	228_L	0.722	0.37
192_M	208_Y	0.719	0.36
34_I	97_K	0.716	0.36
55_I	77_W	0.715	0.36
232_D	237_Y	0.714	0.36
82_F	93_W	0.712	0.36
56_R	158_Y	0.709	0.36
256_A	263_A	0.709	0.36
84_E	93_W	0.707	0.35
43_K	82_F	0.707	0.35
266_I	274_F	0.699	0.35
140_I	151_N	0.699	0.35
187_G	191_E	0.695	0.35
136_C	139_C	0.694	0.34
114_S	137_G	0.692	0.34
37_S	212_G	0.692	0.34
130_S	156_R	0.692	0.34
60_G	151_N	0.691	0.34
101_M	226_Y	0.690	0.34
113_P	116_G	0.690	0.34
72_L	161_T	0.688	0.34
67_D	70_A	0.687	0.34
145_F	214_Y	0.685	0.34
185_H	201_A	0.685	0.34
214_Y	221_G	0.684	0.34
227_V	248_T	0.681	0.34
257_L	264_G	0.676	0.33
110_K	223_H	0.673	0.33
125_I	147_I	0.672	0.33
43_K	181_T	0.671	0.33
80_M	121_Y	0.670	0.33
44_A	104_E	0.669	0.33
106_P	121_Y	0.667	0.33
253_W	259_P	0.661	0.32
95_I	183_A	0.659	0.32
37_S	199_R	0.657	0.32
190_K	194_E	0.656	0.32
36_V	228_L	0.651	0.31
130_S	158_Y	0.649	0.31
34_I	184_I	0.649	0.31
137_G	154_D	0.646	0.31
43_K	95_I	0.643	0.31
233_Q	236_L	0.640	0.31
46_Q	116_G	0.640	0.31
195_L	199_R	0.639	0.31
43_K	207_G	0.639	0.31
48_A	174_A	0.633	0.30
25_D	122_A	0.633	0.30
256_A	271_G	0.629	0.30
34_I	183_A	0.627	0.30
204_K	209_E	0.626	0.30
87_Q	198_Q	0.623	0.30
31_A	225_M	0.620	0.29
73_S	227_V	0.619	0.29
243_D	246_I	0.618	0.29
260_L	274_F	0.617	0.29
263_A	267_A	0.616	0.29
100_C	143_C	0.616	0.29
100_C	108_C	0.616	0.29
103_C	179_C	0.616	0.29
108_C	143_C	0.616	0.29
103_C	108_C	0.616	0.29
100_C	103_C	0.616	0.29
143_C	179_C	0.616	0.29
103_C	143_C	0.616	0.29
100_C	179_C	0.616	0.29
108_C	179_C	0.616	0.29
41_G	222_T	0.611	0.29
96_R	254_K	0.610	0.29
143_C	175_C	0.609	0.29
103_C	175_C	0.609	0.29
108_C	175_C	0.609	0.29
175_C	179_C	0.609	0.29
100_C	175_C	0.609	0.29
188_T	192_M	0.607	0.29
90_K	169_V	0.606	0.28
34_I	165_D	0.605	0.28
182_G	217_E	0.604	0.28
116_G	121_Y	0.604	0.28
135_G	222_T	0.603	0.28
40_I	69_P	0.602	0.28
196_A	199_R	0.601	0.28
256_A	269_F	0.601	0.28
86_E	89_G	0.601	0.28
168_S	271_G	0.600	0.28
119_I	127_D	0.598	0.28
31_A	54_D	0.597	0.28
275_H	279_I	0.595	0.28
34_I	113_P	0.594	0.28
189_K	196_A	0.593	0.28
123_N	127_D	0.584	0.27
234_P	240_L	0.583	0.27
111_A	142_G	0.581	0.27
32_K	162_L	0.581	0.27
265_F	277_I	0.580	0.27
189_K	215_N	0.578	0.27
57_D	171_Q	0.575	0.26
40_I	111_A	0.571	0.26
213_V	261_A	0.571	0.26
200_V	212_G	0.568	0.26
214_Y	244_P	0.568	0.26
257_L	268_T	0.566	0.26
148_P	196_A	0.565	0.26
122_A	236_L	0.565	0.26
182_G	192_M	0.561	0.26
85_T	263_A	0.560	0.26
41_G	80_M	0.560	0.26
112_C	136_C	0.559	0.25
129_Q	194_E	0.559	0.25
151_N	156_R	0.558	0.25
56_R	166_R	0.558	0.25
106_P	195_L	0.557	0.25
110_K	232_D	0.555	0.25
273_I	277_I	0.555	0.25
169_V	251_S	0.554	0.25
40_I	180_P	0.553	0.25
185_H	198_Q	0.552	0.25
39_C	49_C	0.551	0.25
42_C	49_C	0.551	0.25
45_C	49_C	0.551	0.25
72_L	149_R	0.551	0.25
50_S	76_S	0.550	0.25
52_W	84_E	0.548	0.25
200_V	225_M	0.546	0.25
33_L	221_G	0.545	0.25
260_L	280_G	0.545	0.25
36_V	40_I	0.544	0.25
242_K	246_I	0.541	0.24
99_G	183_A	0.540	0.24
133_C	136_C	0.540	0.24
118_I	165_D	0.538	0.24
127_D	164_V	0.536	0.24
99_G	140_I	0.530	0.24
111_A	267_A	0.529	0.24
44_A	95_I	0.527	0.24
174_A	240_L	0.526	0.24
40_I	113_P	0.525	0.23
265_F	268_T	0.525	0.23
196_A	225_M	0.523	0.23
265_F	278_G	0.523	0.23
260_L	264_G	0.521	0.23
257_L	266_I	0.520	0.23
46_Q	80_M	0.518	0.23
158_Y	222_T	0.517	0.23
50_S	262_A	0.517	0.23
245_K	269_F	0.516	0.23
38_T	129_Q	0.515	0.23
218_G	222_T	0.515	0.23
164_V	249_S	0.514	0.23
258_K	262_A	0.514	0.23
258_K	261_A	0.513	0.23
84_E	91_L	0.513	0.23
189_K	221_G	0.512	0.23
41_G	239_G	0.507	0.22
109_L	120_Q	0.506	0.22
252_L	255_G	0.505	0.22
86_E	170_G	0.500	0.22
166_R	174_A	0.500	0.22

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1kqfB	3	0.983	100	0.398	Contact Map
1h0hB	1	0.7075	100	0.542	Contact Map
2ivfB	1	0.8707	100	0.585	Contact Map
1ti6B	2	0.8401	100	0.606	Contact Map
2vpzB	2	0.6565	100	0.643	Contact Map
1q16B	2	0.898	100	0.674	Contact Map
4z3xE	2	0.5782	100	0.735	Contact Map
3mm5B	2	0.8469	99.8	0.808	Contact Map
1jnrB	1	0.5	99.4	0.858	Contact Map
2fgoA	1	0.2517	99.4	0.858	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0098 seconds.