GREMLIN Database
FTSH - ATP-dependent zinc metalloprotease FtsH
UniProt: P0AAI3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11506
Length: 644 (590)
Sequences: 4859 (2658)
Seq/√Len: 109.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
568_M572_H5.8291.00
562_Q566_D4.8671.00
328_E347_A3.9271.00
551_A555_R3.8811.00
321_L357_S3.7861.00
466_I556_N3.6211.00
479_I568_M3.6041.00
335_M365_V3.6011.00
169_E177_F3.5881.00
328_E332_K3.5851.00
338_V380_V3.4451.00
377_K384_E3.4421.00
540_E543_R3.4091.00
40_E45_Q3.3591.00
424_L563_L3.2501.00
238_E242_K3.2381.00
512_K544_I3.2081.00
335_M346_A3.1871.00
331_L361_L3.1451.00
581_Y588_Q3.0801.00
477_E561_R3.0651.00
572_H576_D3.0291.00
365_V385_F2.9651.00
504_V552_L2.9061.00
421_I467_S2.8691.00
561_R565_T2.8641.00
478_I564_L2.8351.00
424_L567_N2.8081.00
479_I571_L2.8041.00
460_Q484_H2.7811.00
512_K548_E2.7521.00
491_N494_K2.7481.00
377_K381_S2.7451.00
467_S556_N2.7351.00
427_E464_S2.7331.00
567_N570_I2.7171.00
179_K378_R2.7161.00
479_I572_H2.7031.00
409_E576_D2.7001.00
466_I500_A2.6151.00
469_L495_V2.5971.00
66_Y71_P2.5851.00
416_A574_M2.5211.00
477_E557_Y2.5201.00
512_K547_Q2.4811.00
496_A553_I2.4271.00
550_K554_E2.4171.00
411_T456_S2.4161.00
466_I552_L2.4031.00
381_S384_E2.3981.00
422_G448_F2.3711.00
467_S560_A2.3451.00
175_S179_K2.3361.00
474_L561_R2.3271.00
115_V119_F2.3191.00
375_G387_K2.2651.00
183_K362_A2.2561.00
558_N562_Q2.2281.00
76_K79_D2.2161.00
462_L499_L2.2151.00
487_T507_W2.1611.00
448_F468_T2.1601.00
502_N507_W2.1511.00
557_Y561_R2.1231.00
435_T583_T2.1141.00
510_S548_E2.0771.00
375_G384_E2.0591.00
33_D36_T2.0541.00
422_G468_T2.0501.00
491_N495_V2.0411.00
164_V205_I2.0251.00
425_V464_S2.0201.00
214_F243_A1.9981.00
454_A461_K1.9911.00
502_N506_Q1.9881.00
577_A584_I1.9841.00
423_R590_D1.9791.00
463_E555_R1.9681.00
44_D84_K1.9581.00
257_G307_L1.9521.00
37_F41_V1.9451.00
478_I565_T1.9221.00
329_Q332_K1.9171.00
408_K579_M1.9081.00
459_R463_E1.9031.00
372_A384_E1.8991.00
463_E556_N1.8911.00
41_V46_V1.8601.00
342_P379_V1.8571.00
516_L553_I1.8511.00
176_R376_N1.8331.00
467_S559_R1.8301.00
341_A379_V1.7951.00
585_D588_Q1.7821.00
410_S480_Y1.7651.00
113_I117_I1.7581.00
42_N80_N1.7401.00
48_E59_T1.7131.00
46_V60_K1.6881.00
443_L456_S1.6881.00
434_V446_T1.6751.00
338_V365_V1.6711.00
464_S559_R1.6611.00
431_V446_T1.6601.00
406_A409_E1.6591.00
335_M385_F1.6541.00
79_D83_T1.6461.00
98_L102_I1.6451.00
241_K288_N1.6451.00
410_S486_S1.6341.00
325_R328_E1.6311.00
577_A581_Y1.6301.00
554_E558_N1.6281.00
167_L188_V1.6261.00
68_T71_P1.6071.00
109_M113_I1.5931.00
110_L114_G1.5851.00
158_D326_G1.5851.00
518_Y545_I1.5771.00
462_L487_T1.5671.00
340_L346_A1.5621.00
576_D580_K1.5541.00
459_R511_E1.5521.00
565_T568_M1.5441.00
37_F49_A1.5351.00
465_Q495_V1.5161.00
420_I574_M1.5091.00
201_L319_V1.5051.00
69_Y72_V1.4991.00
413_Y572_H1.4931.00
48_E87_K1.4781.00
341_A381_S1.4751.00
543_R547_Q1.4691.00
558_N561_R1.4661.00
66_Y69_Y1.4551.00
246_C291_I1.4511.00
469_L499_L1.4511.00
428_H468_T1.4501.00
442_A445_V1.4481.00
383_V387_K1.4471.00
345_D348_I1.4381.00
559_R562_Q1.4311.00
474_L557_Y1.4291.00
390_D433_K1.4181.00
409_E480_Y1.4171.00
114_G118_F1.4021.00
413_Y576_D1.3971.00
36_T40_E1.3851.00
548_E551_A1.3841.00
67_T70_I1.3771.00
106_W110_L1.3681.00
49_A56_I1.3681.00
586_A590_D1.3591.00
428_H464_S1.3571.00
80_N84_K1.3501.00
371_F384_E1.3481.00
540_E544_I1.3471.00
570_I593_M1.3401.00
570_I573_A1.3391.00
544_I547_Q1.3381.00
458_S486_S1.3371.00
493_I517_L1.3311.00
428_H448_F1.3250.99
32_V58_V1.3150.99
40_E60_K1.3050.99
478_I561_R1.3030.99
498_N502_N1.2990.99
67_T71_P1.2890.99
420_I571_L1.2870.99
77_L81_L1.2800.99
500_A552_L1.2780.99
36_T39_Q1.2760.99
432_H449_L1.2720.99
262_A526_F1.2710.99
424_L570_I1.2710.99
108_P111_L1.2670.99
39_Q43_N1.2660.99
473_R489_A1.2650.99
117_I121_R1.2590.99
526_F529_R1.2570.99
474_L565_T1.2540.99
463_E467_S1.2530.99
67_T72_V1.2430.99
537_M542_A1.2430.99
421_I560_A1.2430.99
82_L88_V1.2360.99
480_Y486_S1.2350.99
239_Q242_K1.2300.99
240_A248_I1.2200.99
573_A595_R1.2200.99
149_T203_K1.2120.99
136_K139_A1.2090.99
478_I568_M1.2090.99
352_G389_K1.2080.99
193_P320_G1.2080.99
414_H418_H1.2040.99
151_F168_V1.1980.99
574_M592_L1.1970.99
386_E432_H1.1970.99
41_V84_K1.1910.99
405_E409_E1.1890.99
513_L518_Y1.1830.99
469_L496_A1.1810.99
160_A320_G1.1800.99
364_L389_K1.1780.99
560_A563_L1.1780.99
421_I471_G1.1720.99
573_A577_A1.1710.99
434_V589_I1.1670.99
131_A134_F1.1660.99
406_A452_G1.1650.99
203_K287_G1.1610.99
577_A591_D1.1590.99
475_A571_L1.1580.99
15_L19_F1.1560.99
469_L491_N1.1550.99
418_H488_G1.1490.99
335_M340_L1.1480.99
205_I294_I1.1470.99
259_Q529_R1.1410.98
328_E346_A1.1330.98
220_D277_Q1.1260.98
107_F110_L1.1230.98
423_R589_I1.1180.98
47_R61_K1.1180.98
513_L545_I1.1180.98
463_E559_R1.1100.98
425_V428_H1.1080.98
325_R329_Q1.1050.98
587_P591_D1.1040.98
137_S235_D1.1040.98
264_L527_L1.1030.98
591_D596_R1.1000.98
389_K394_M1.0960.98
421_I563_L1.0950.98
34_Y74_D1.0920.98
474_L560_A1.0910.98
588_Q591_D1.0870.98
512_K551_A1.0850.98
81_L86_V1.0830.98
457_A461_K1.0800.98
387_K397_E1.0760.98
32_V40_E1.0750.98
347_A351_R1.0730.98
356_F364_L1.0720.98
564_L571_L1.0700.98
591_D595_R1.0680.98
158_D329_Q1.0650.98
429_D465_Q1.0640.98
144_E147_I1.0580.98
8_W12_A1.0580.98
416_A575_K1.0560.97
493_I516_L1.0520.97
10_V17_S1.0500.97
448_F469_L1.0470.97
481_G484_H1.0430.97
412_A579_M1.0400.97
108_P123_M1.0400.97
180_L373_A1.0370.97
419_A584_I1.0350.97
323_D326_G1.0350.97
466_I496_A1.0320.97
14_V18_V1.0310.97
394_M401_M1.0280.97
331_L349_I1.0250.97
410_S456_S1.0240.97
573_A592_L1.0220.97
222_V270_E1.0210.97
246_C290_G1.0210.97
407_Q456_S1.0190.97
162_E165_A1.0190.97
112_L116_W1.0180.97
44_D85_N1.0150.97
413_Y479_I1.0060.97
535_K539_D1.0020.97
8_W22_F1.0020.97
188_V292_I0.9970.96
348_I386_E0.9910.96
574_M589_I0.9900.96
467_S563_L0.9890.96
416_A420_I0.9780.96
167_L205_I0.9770.96
118_F122_Q0.9770.96
38_L82_L0.9710.96
414_H488_G0.9710.96
448_F465_Q0.9680.96
413_Y575_K0.9660.96
431_V434_V0.9660.96
49_A81_L0.9620.96
495_V498_N0.9620.96
71_P74_D0.9600.96
258_R302_V0.9590.96
435_T445_V0.9590.96
410_S443_L0.9560.95
200_L358_G0.9550.95
352_G391_K0.9520.95
70_I73_Q0.9510.95
104_I108_P0.9500.95
33_D87_K0.9490.95
544_I550_K0.9480.95
577_A580_K0.9450.95
331_L346_A0.9440.95
405_E408_K0.9400.95
494_K498_N0.9400.95
565_T569_D0.9370.95
255_A280_V0.9360.95
47_R59_T0.9350.95
574_M584_I0.9320.95
62_D65_R0.9310.95
139_A142_L0.9310.95
390_D445_V0.9260.95
556_N559_R0.9230.95
184_I292_I0.9230.95
202_A358_G0.9230.95
406_A410_S0.9220.94
98_L104_I0.9210.94
79_D82_L0.9200.94
515_P554_E0.9100.94
163_E391_K0.9100.94
348_I382_M0.9090.94
500_A549_V0.9040.94
74_D77_L0.9030.94
109_M114_G0.9020.94
17_S21_S0.9010.94
69_Y73_Q0.8980.94
594_A597_D0.8940.94
562_Q565_T0.8940.94
169_E173_E0.8910.93
423_R593_M0.8900.93
510_S551_A0.8900.93
461_K465_Q0.8890.93
577_A588_Q0.8840.93
32_V36_T0.8840.93
37_F58_V0.8820.93
157_C326_G0.8800.93
569_D573_A0.8760.93
505_T545_I0.8730.93
300_P527_L0.8730.93
462_L507_W0.8730.93
590_D594_A0.8670.92
102_I106_W0.8670.92
38_L80_N0.8660.92
464_S467_S0.8650.92
19_F23_G0.8600.92
16_M20_Q0.8590.92
188_V317_V0.8580.92
391_K394_M0.8580.92
107_F114_G0.8570.92
443_L455_I0.8570.92
163_E396_A0.8570.92
465_Q469_L0.8550.92
214_F239_Q0.8540.92
349_I361_L0.8510.92
547_Q551_A0.8510.92
132_M135_G0.8500.92
349_I385_F0.8490.92
544_I548_E0.8490.92
109_M115_V0.8490.92
78_L88_V0.8480.92
116_W120_M0.8470.92
324_V347_A0.8450.92
434_V584_I0.8430.91
108_P121_R0.8410.91
460_Q464_S0.8400.91
190_M370_L0.8390.91
513_L544_I0.8370.91
164_V167_L0.8370.91
40_E58_V0.8360.91
37_F56_I0.8360.91
8_W20_Q0.8350.91
66_Y70_I0.8330.91
240_A291_I0.8330.91
595_R598_V0.8310.91
109_M116_W0.8310.91
235_D239_Q0.8300.91
157_C160_A0.8300.91
264_L529_R0.8290.91
50_R57_N0.8290.91
268_H271_R0.8280.91
419_A434_V0.8270.91
539_D543_R0.8250.91
113_I116_W0.8230.90
244_A290_G0.8210.90
513_L541_T0.8210.90
409_E413_Y0.8100.90
18_V22_F0.8090.90
338_V385_F0.8070.90
427_E460_Q0.8060.89
368_A385_F0.8060.89
397_E445_V0.8030.89
243_A246_C0.8020.89
504_V549_V0.8020.89
433_K583_T0.8010.89
125_G130_G0.8010.89
32_V37_F0.8010.89
573_A576_D0.8000.89
465_Q499_L0.7990.89
30_R36_T0.7990.89
286_E289_E0.7950.89
169_E176_R0.7940.89
572_H575_K0.7940.89
13_V17_S0.7890.88
480_Y485_V0.7890.88
352_G390_D0.7880.88
109_M112_L0.7880.88
552_L556_N0.7860.88
175_S178_Q0.7860.88
390_D447_F0.7850.88
348_I351_R0.7840.88
591_D599_R0.7840.88
38_L46_V0.7830.88
106_W109_M0.7830.88
434_V445_V0.7800.88
34_Y37_F0.7800.88
571_L575_K0.7800.88
108_P112_L0.7790.88
264_L526_F0.7760.88
12_A20_Q0.7750.88
165_A169_E0.7750.88
262_A528_G0.7730.87
403_M408_K0.7720.87
42_N84_K0.7700.87
78_L82_L0.7700.87
58_V66_Y0.7700.87
112_L115_V0.7670.87
69_Y74_D0.7670.87
14_V17_S0.7650.87
403_M411_T0.7630.87
129_K167_L0.7610.87
410_S484_H0.7600.87
470_Y560_A0.7600.87
249_F296_A0.7590.86
217_S280_V0.7580.86
50_R91_E0.7570.86
189_L316_Q0.7570.86
48_E89_V0.7560.86
13_V16_M0.7540.86
555_R562_Q0.7540.86
111_L115_V0.7520.86
80_N83_T0.7510.86
403_M443_L0.7500.86
404_T452_G0.7490.86
480_Y579_M0.7490.86
17_S22_F0.7490.86
178_Q290_G0.7490.86
137_S140_R0.7480.86
76_K80_N0.7480.86
587_P590_D0.7480.86
466_I553_I0.7470.86
97_S101_S0.7460.86
136_K140_R0.7450.85
338_V443_L0.7430.85
554_E557_Y0.7410.85
570_I592_L0.7390.85
134_F228_V0.7380.85
334_H362_A0.7370.85
222_V271_R0.7340.85
420_I424_L0.7340.85
191_V300_P0.7330.85
40_E43_N0.7310.84
41_V86_V0.7310.84
56_I60_K0.7310.84
41_V81_L0.7290.84
44_D61_K0.7270.84
456_S486_S0.7270.84
380_V385_F0.7260.84
132_M136_K0.7240.84
166_E374_R0.7230.84
11_I20_Q0.7230.84
520_E536_H0.7230.84
371_F387_K0.7220.84
535_K542_A0.7200.83
409_E579_M0.7190.83
421_I424_L0.7190.83
539_D542_A0.7180.83
180_L372_A0.7180.83
170_Y184_I0.7180.83
496_A560_A0.7180.83
46_V58_V0.7170.83
157_C205_I0.7170.83
108_P118_F0.7170.83
422_G447_F0.7170.83
114_G117_I0.7160.83
152_A329_Q0.7150.83
191_V317_V0.7150.83
506_Q517_L0.7150.83
514_G557_Y0.7140.83
170_Y285_F0.7140.83
426_P464_S0.7130.83
11_I14_V0.7120.83
147_I150_T0.7110.83
480_Y575_K0.7110.83
191_V316_Q0.7110.83
354_P449_L0.7100.83
352_G386_E0.7100.83
109_M123_M0.7090.83
317_V391_K0.7080.82
116_W123_M0.7070.82
263_G266_G0.7070.82
127_G130_G0.7050.82
108_P116_W0.7040.82
224_M228_V0.7030.82
188_V294_I0.6990.82
389_K445_V0.6970.81
190_M588_Q0.6960.81
500_A504_V0.6960.81
130_G133_S0.6960.81
8_W15_L0.6940.81
97_S100_A0.6940.81
8_W16_M0.6930.81
586_A589_I0.6920.81
460_Q481_G0.6900.81
425_V467_S0.6900.81
258_R269_D0.6880.81
180_L584_I0.6870.80
418_H492_D0.6870.80
105_S112_L0.6860.80
107_F111_L0.6860.80
407_Q454_A0.6850.80
398_R411_T0.6850.80
514_G550_K0.6830.80
340_L344_I0.6830.80
146_Q210_K0.6810.80
581_Y595_R0.6800.80
421_I431_V0.6790.80
316_Q441_R0.6780.80
386_E390_D0.6750.79
470_Y496_A0.6740.79
37_F81_L0.6730.79
333_V362_A0.6730.79
34_Y38_L0.6690.79
159_E323_D0.6670.79
570_I596_R0.6670.79
415_E418_H0.6670.79
72_V77_L0.6660.78
411_T455_I0.6650.78
386_E592_L0.6650.78
480_Y571_L0.6640.78
38_L42_N0.6640.78
424_L593_M0.6640.78
73_Q76_K0.6630.78
152_A336_R0.6630.78
20_Q24_P0.6630.78
401_M507_W0.6630.78
340_L365_V0.6630.78
458_S484_H0.6610.78
123_M126_G0.6590.78
153_D336_R0.6590.78
8_W18_V0.6580.78
457_A499_L0.6580.78
562_Q567_N0.6560.77
555_R559_R0.6560.77
31_K36_T0.6560.77
511_E551_A0.6560.77
135_G231_S0.6540.77
541_T544_I0.6510.77
85_N88_V0.6510.77
256_V301_D0.6510.77
130_G134_F0.6500.77
318_V441_R0.6500.77
160_A433_K0.6480.77
12_A22_F0.6470.76
36_T87_K0.6460.76
268_H529_R0.6460.76
145_D148_K0.6450.76
105_S116_W0.6430.76
8_W17_S0.6430.76
500_A553_I0.6430.76
488_G492_D0.6420.76
10_V13_V0.6410.76
371_F396_A0.6390.76
36_T47_R0.6390.76
406_A484_H0.6380.75
263_G269_D0.6370.75
226_V285_F0.6370.75
12_A16_M0.6360.75
18_V21_S0.6360.75
493_I515_P0.6360.75
230_A273_Q0.6350.75
524_E530_S0.6350.75
412_A504_V0.6340.75
409_E572_H0.6340.75
558_N565_T0.6330.75
463_E552_L0.6330.75
222_V230_A0.6320.75
338_V362_A0.6320.75
150_T200_L0.6320.75
58_V68_T0.6310.75
76_K82_L0.6310.75
49_A86_V0.6300.74
407_Q455_I0.6300.74
343_D381_S0.6290.74
398_R401_M0.6290.74
356_F393_M0.6280.74
142_L145_D0.6280.74
8_W19_F0.6270.74
436_I443_L0.6270.74
45_Q61_K0.6260.74
324_V328_E0.6260.74
530_S536_H0.6240.74
222_V269_D0.6240.74
570_I595_R0.6220.74
516_L545_I0.6220.74
417_G488_G0.6210.73
10_V14_V0.6210.73
387_K439_R0.6200.73
103_F107_F0.6200.73
555_R558_N0.6190.73
390_D456_S0.6190.73
50_R59_T0.6190.73
573_A580_K0.6190.73
186_K290_G0.6160.73
425_V563_L0.6160.73
241_K339_P0.6160.73
161_K168_V0.6150.73
151_F164_V0.6140.73
11_I19_F0.6140.73
538_S543_R0.6140.73
160_A398_R0.6130.72
96_P100_A0.6120.72
337_R380_V0.6090.72
403_M410_S0.6090.72
214_F236_M0.6090.72
75_P78_L0.6080.72
186_K362_A0.6080.72
126_G225_F0.6070.72
414_H417_G0.6060.72
516_L549_V0.6050.72
528_G531_V0.6050.72
487_T491_N0.6040.71
49_A58_V0.6030.71
19_F22_F0.6020.71
446_T471_G0.6020.71
527_L533_K0.6020.71
321_L441_R0.6020.71
343_D382_M0.6010.71
475_A479_I0.6000.71
324_V351_R0.6000.71
118_F121_R0.6000.71
291_I533_K0.5990.71
498_N520_E0.5990.71
326_G357_S0.5990.71
244_A291_I0.5980.71
9_L16_M0.5970.71
394_M461_K0.5970.71
437_I584_I0.5970.71
34_Y77_L0.5970.71
157_C329_Q0.5960.70
105_S113_I0.5960.70
44_D86_V0.5960.70
263_G301_D0.5960.70
10_V19_F0.5950.70
527_L531_V0.5950.70
431_V445_V0.5950.70
262_A529_R0.5940.70
106_W112_L0.5930.70
58_V67_T0.5930.70
96_P101_S0.5920.70
77_L88_V0.5920.70
334_H337_R0.5920.70
178_Q182_G0.5920.70
339_P379_V0.5920.70
400_S403_M0.5910.70
462_L502_N0.5910.70
45_Q62_D0.5900.70
429_D450_P0.5890.69
105_S108_P0.5890.69
135_G139_A0.5880.69
277_Q281_E0.5880.69
485_V557_Y0.5870.69
389_K393_M0.5870.69
407_Q461_K0.5870.69
236_M248_I0.5870.69
418_H444_G0.5860.69
270_E367_E0.5860.69
125_G129_K0.5860.69
259_Q305_P0.5850.69
510_S514_G0.5850.69
447_F457_A0.5850.69
179_K339_P0.5850.69
321_L326_G0.5850.69
220_D280_V0.5840.69
214_F399_R0.5840.69
526_F531_V0.5830.69
74_D90_G0.5810.68
300_P319_V0.5810.68
472_G492_D0.5810.68
52_N57_N0.5810.68
104_I107_F0.5800.68
33_D39_Q0.5800.68
447_F574_M0.5800.68
172_R210_K0.5790.68
186_K293_V0.5780.68
393_M447_F0.5780.68
241_K286_E0.5770.68
100_A103_F0.5770.68
278_M316_Q0.5760.68
73_Q78_L0.5760.68
59_T63_S0.5750.68
446_T493_I0.5750.68
133_S136_K0.5740.68
456_S507_W0.5740.68
501_R549_V0.5740.68
112_L117_I0.5720.67
247_I402_V0.5720.67
375_G383_V0.5710.67
9_L14_V0.5700.67
256_V295_A0.5680.67
394_M432_H0.5670.67
594_A598_V0.5670.67
446_T589_I0.5660.66
112_L119_F0.5660.66
428_H493_I0.5650.66
310_P392_I0.5650.66
365_V368_A0.5650.66
13_V20_Q0.5650.66
300_P318_V0.5640.66
401_M445_V0.5640.66
535_K541_T0.5630.66
173_E176_R0.5630.66
224_M235_D0.5620.66
470_Y553_I0.5620.66
540_E547_Q0.5620.66
143_T148_K0.5620.66
467_S474_L0.5600.66
521_E531_V0.5590.65
335_M361_L0.5590.65
529_R536_H0.5590.65
493_I496_A0.5580.65
159_E326_G0.5580.65
414_H492_D0.5570.65
390_D422_G0.5570.65
70_I74_D0.5560.65
333_V585_D0.5550.65
121_R125_G0.5550.65
530_S533_K0.5550.65
11_I18_V0.5540.65
163_E440_G0.5540.65
189_L300_P0.5530.65
13_V19_F0.5520.65
519_A536_H0.5510.64
481_G485_V0.5510.64
390_D435_T0.5500.64
10_V125_G0.5500.64
445_V448_F0.5490.64
523_G527_L0.5480.64
81_L88_V0.5480.64
77_L80_N0.5470.64
597_D600_P0.5470.64
351_R580_K0.5460.64
117_I120_M0.5460.64
11_I15_L0.5450.64
88_V92_P0.5440.63
15_L22_F0.5440.63
431_V468_T0.5440.63
109_M119_F0.5440.63
418_H489_A0.5430.63
382_M386_E0.5430.63
31_K89_V0.5430.63
158_D325_R0.5430.63
109_M121_R0.5420.63
409_E479_I0.5420.63
530_S537_M0.5420.63
576_D579_M0.5420.63
9_L13_V0.5410.63
100_A104_I0.5410.63
556_N560_A0.5400.63
125_G128_G0.5400.63
178_Q186_K0.5390.63
111_L114_G0.5380.63
9_L17_S0.5380.63
42_N87_K0.5380.63
501_R536_H0.5370.62
406_A461_K0.5370.62
573_A597_D0.5370.62
416_A589_I0.5370.62
515_P557_Y0.5360.62
423_R586_A0.5350.62
438_P473_R0.5350.62
136_K235_D0.5350.62
402_V410_S0.5340.62
74_D78_L0.5340.62
15_L23_G0.5330.62
9_L12_A0.5320.62
460_Q463_E0.5310.62
9_L18_V0.5310.62
229_G274_T0.5310.62
258_R261_G0.5310.62
419_A589_I0.5300.61
374_R391_K0.5300.61
42_N82_L0.5300.61
240_A505_T0.5290.61
352_G449_L0.5290.61
444_G508_G0.5290.61
305_P528_G0.5290.61
49_A88_V0.5280.61
516_L550_K0.5280.61
253_I333_V0.5280.61
51_I90_G0.5280.61
155_A333_V0.5280.61
188_V453_D0.5280.61
47_R62_D0.5280.61
477_E481_G0.5280.61
398_R445_V0.5270.61
444_G488_G0.5270.61
577_A592_L0.5270.61
14_V22_F0.5260.61
17_S20_Q0.5260.61
531_V536_H0.5240.61
182_G380_V0.5240.61
448_F464_S0.5220.60
15_L30_R0.5220.60
471_G493_I0.5210.60
265_G529_R0.5210.60
353_T361_L0.5210.60
53_G74_D0.5210.60
564_L574_M0.5210.60
415_E444_G0.5200.60
241_K289_E0.5190.60
148_K203_K0.5190.60
59_T62_D0.5180.60
379_V593_M0.5180.60
432_H447_F0.5180.60
501_R505_T0.5170.60
489_A492_D0.5170.60
19_F106_W0.5170.60
458_S461_K0.5170.60
300_P441_R0.5170.60
217_S269_D0.5160.59
104_I109_M0.5160.59
365_V380_V0.5160.59
137_S141_M0.5150.59
183_K454_A0.5150.59
38_L88_V0.5150.59
182_G583_T0.5140.59
324_V402_V0.5140.59
323_D401_M0.5140.59
183_K337_R0.5120.59
70_I92_P0.5120.59
523_G530_S0.5120.59
66_Y72_V0.5120.59
9_L20_Q0.5110.59
9_L22_F0.5110.59
406_A427_E0.5110.59
592_L595_R0.5110.59
108_P114_G0.5110.59
164_V188_V0.5110.59
67_T73_Q0.5110.59
394_M421_I0.5100.59
422_G433_K0.5090.58
348_I352_G0.5090.58
411_T469_L0.5090.58
20_Q23_G0.5090.58
437_I553_I0.5090.58
11_I16_M0.5090.58
435_T446_T0.5090.58
377_K383_V0.5080.58
371_F388_A0.5080.58
387_K396_A0.5080.58
74_D81_L0.5070.58
69_Y75_P0.5070.58
408_K437_I0.5060.58
435_T438_P0.5050.58
164_V292_I0.5050.58
435_T495_V0.5050.58
39_Q83_T0.5050.58
72_V75_P0.5040.58
99_L102_I0.5040.58
397_E443_L0.5040.58
413_Y480_Y0.5040.58
41_V80_N0.5040.58
538_S541_T0.5030.57
97_S102_I0.5030.57
415_E473_R0.5020.57
16_M21_S0.5020.57
414_H444_G0.5020.57
261_G264_L0.5010.57
112_L121_R0.5010.57
527_L536_H0.5010.57
35_S88_V0.5010.57
397_E437_I0.5010.57
376_N458_S0.5010.57
50_R75_P0.5010.57
98_L101_S0.5010.57
259_Q264_L0.5000.57
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2ce7A 3 0.6661 100 0.399 Contact Map
4ww0A 4 0.6724 100 0.407 Contact Map
2dhrA 5 0.7112 100 0.442 Contact Map
4cr2J 1 0.5637 100 0.664 Contact Map
4cr2I 1 0.5606 100 0.682 Contact Map
4cr2K 1 0.573 100 0.694 Contact Map
4cr2L 1 0.5466 100 0.697 Contact Map
4cr2M 1 0.5512 100 0.7 Contact Map
4cr2H 1 0.5404 100 0.703 Contact Map
3cf2A 3 0.5047 100 0.705 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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