POTE - ECOLI - GREMLIN Contacts

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POTE - Putrescine-ornithine antiporter

UniProt:	P0AAF1	Sequences: MSQAKSNKMGVVQLTILTMVNMMGSGIIMLPTKLAEVGTISIISWLVTAVGSMALAWAFAKCGMFSRKSGGMGGYAEYAFGKSGNFMANYTYGVSLLIANVAIAISAVGYGTELLGASLSPVQIGLATIGVLWICTVANFGGARITGQISSITVWGVIIPVVGLCIIGWFWFSPTLYVDSWNPHHAPFFSAVGSSIAMTLWAFLGLESACANTDVVENPERNVPIAVLGGTLGAAVIYIVSTNVIAGIVPNMELANSTAPFGLAFAQMFTPEVGKVIMALMVMSCCGSLLGWQFTIAQVFKSSSDEGYFPKIFSRVTKVDAPVQGMLTIVIIQSGLALMTISPSLNSQFNVLVNLAVVTNIIPYILSMAALVIIQKVANVPPSKAKVANFVAFVGAMYSFYALYSSGEEAMLYGSIVTFLGWTLYGLVSPRFELKNKHG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10753
Length:	439 (411)
Sequences:	24546 (15546)
Seq/√Len:	766.8

ECOLI - POTE ADIC PROY AROP FRLA YIFK CADB ANSP PLAP PUUP YGJI LYSP PHEP MMUP YCAM GABP YBAT YJEH CYCA GADC ARCD YJEM TNAB MTR TYRP
BACSU - YBXG YBEC GABP YTNA YHDG ARCD YVBW ASPP YECA ROCC YDGF YFNA AAPA YBGF HUTM YCGH STET ROCE YDAO GERBB YNDE GERAB GERKB YFKT
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97U05 Q97XM0 Q7LXI7 Q97X49 Q97WS3 Q97ZB5 Q97Y76 Q97Z63 Q97U33 Q97WD4 Q97VR4 Q97VA6 Q97VA8 Q97YN3 Q97YX9 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
136_T	330_V	4.425	1.00
312_I	324_Q	4.315	1.00
379_N	383_S	3.525	1.00
365_I	396_A	3.288	1.00
49_A	235_A	3.244	1.00
373_I	377_V	3.195	1.00
315_R	324_Q	3.113	1.00
221_R	225_I	2.976	1.00
10_G	217_E	2.965	1.00
73_G	306_E	2.751	1.00
216_V	222_N	2.745	1.00
89_N	303_S	2.654	1.00
304_S	314_S	2.584	1.00
218_N	221_R	2.526	1.00
168_G	244_V	2.517	1.00
317_T	323_V	2.501	1.00
312_I	315_R	2.481	1.00
129_I	334_S	2.477	1.00
166_I	170_F	2.416	1.00
15_T	229_G	2.406	1.00
11_V	229_G	2.377	1.00
214_D	305_D	2.357	1.00
368_M	395_G	2.319	1.00
61_K	375_Q	2.314	1.00
215_V	298_Q	2.280	1.00
77_E	85_N	2.228	1.00
393_F	397_M	2.190	1.00
301_K	305_D	2.143	1.00
11_V	222_N	2.128	1.00
327_L	331_I	2.126	1.00
137_V	141_G	2.125	1.00
136_T	326_M	2.094	1.00
80_F	373_I	2.089	1.00
263_L	266_A	2.088	1.00
11_V	15_T	2.074	1.00
14_L	216_V	2.065	1.00
144_R	148_Q	2.049	1.00
140_F	323_V	2.023	1.00
133_W	334_S	2.011	1.00
225_I	229_G	2.000	1.00
253_E	267_Q	1.990	1.00
423_T	427_L	1.956	1.00
10_G	13_Q	1.956	1.00
128_T	337_A	1.944	1.00
155_W	159_I	1.936	1.00
129_I	337_A	1.899	1.00
380_V	383_S	1.878	1.00
272_E	276_V	1.878	1.00
58_A	368_M	1.871	1.00
313_F	328_T	1.871	1.00
77_E	82_K	1.870	1.00
93_G	329_I	1.866	1.00
50_V	54_A	1.846	1.00
307_G	311_K	1.844	1.00
250_P	253_E	1.834	1.00
379_N	382_P	1.833	1.00
369_A	396_A	1.820	1.00
80_F	369_A	1.812	1.00
13_Q	151_S	1.775	1.00
81_G	84_G	1.773	1.00
139_N	290_L	1.772	1.00
263_L	267_Q	1.772	1.00
34_L	41_S	1.771	1.00
317_T	321_A	1.748	1.00
133_W	330_V	1.742	1.00
218_N	222_N	1.736	1.00
228_L	232_L	1.716	1.00
76_A	88_A	1.707	1.00
51_G	398_Y	1.704	1.00
397_M	401_Y	1.702	1.00
417_V	421_G	1.653	1.00
104_A	289_L	1.633	1.00
390_F	394_V	1.633	1.00
319_V	323_V	1.631	1.00
140_F	327_L	1.620	1.00
18_T	230_G	1.606	1.00
44_S	195_S	1.600	1.00
373_I	376_K	1.598	1.00
159_I	163_G	1.595	1.00
132_L	333_Q	1.584	1.00
88_A	366_L	1.580	1.00
15_T	233_G	1.571	1.00
123_Q	126_L	1.571	1.00
40_I	192_V	1.551	1.00
415_S	419_F	1.530	1.00
111_G	127_A	1.528	1.00
9_M	13_Q	1.513	1.00
232_L	236_V	1.500	1.00
182_N	186_A	1.485	1.00
301_K	316_V	1.482	1.00
178_V	181_W	1.478	1.00
422_W	426_G	1.472	1.00
266_A	274_G	1.464	1.00
324_Q	328_T	1.462	1.00
122_V	126_L	1.451	1.00
48_T	199_T	1.449	1.00
257_S	263_L	1.449	1.00
212_N	294_F	1.449	1.00
100_N	333_Q	1.448	1.00
54_A	394_V	1.447	1.00
300_F	325_G	1.443	1.00
387_V	391_V	1.442	1.00
56_A	231_T	1.436	1.00
311_K	314_S	1.429	1.00
160_P	280_L	1.423	1.00
107_A	131_V	1.423	1.00
107_A	282_V	1.421	1.00
90_Y	421_G	1.417	1.00
104_A	132_L	1.417	1.00
136_T	327_L	1.416	1.00
129_I	133_W	1.411	1.00
6_S	320_D	1.410	1.00
169_W	244_V	1.406	1.00
369_A	373_I	1.404	1.00
141_G	319_V	1.392	1.00
218_N	225_I	1.384	1.00
50_V	394_V	1.383	1.00
158_I	162_V	1.383	1.00
296_I	329_I	1.382	1.00
269_F	273_V	1.363	1.00
275_K	279_A	1.359	1.00
311_K	315_R	1.354	1.00
219_P	224_P	1.349	1.00
315_R	323_V	1.347	1.00
132_L	330_V	1.339	1.00
76_A	366_L	1.339	1.00
69_S	214_D	1.338	1.00
416_I	420_L	1.337	1.00
13_Q	147_G	1.333	1.00
172_F	247_G	1.330	1.00
388_A	392_A	1.320	1.00
421_G	424_L	1.319	1.00
365_I	400_F	1.301	1.00
56_A	227_V	1.294	1.00
9_M	14_L	1.294	1.00
297_A	326_M	1.293	1.00
222_N	225_I	1.285	1.00
165_C	240_V	1.273	1.00
66_S	78_Y	1.271	1.00
42_I	243_N	1.268	1.00
266_A	271_P	1.266	1.00
384_K	387_V	1.266	1.00
79_A	370_A	1.260	1.00
11_V	225_I	1.255	1.00
401_Y	405_S	1.253	1.00
236_V	240_V	1.252	1.00
68_K	74_G	1.248	1.00
57_W	228_L	1.243	1.00
80_F	84_G	1.240	1.00
103_I	288_S	1.237	1.00
9_M	147_G	1.234	1.00
125_G	129_I	1.234	1.00
372_V	393_F	1.228	1.00
55_L	368_M	1.227	1.00
385_A	388_A	1.226	1.00
135_C	289_L	1.223	1.00
168_G	248_I	1.217	1.00
300_F	309_F	1.217	1.00
22_M	234_A	1.211	1.00
58_A	392_A	1.208	1.00
182_N	185_H	1.208	1.00
74_G	78_Y	1.205	1.00
83_S	428_V	1.202	1.00
12_V	16_I	1.196	1.00
164_L	168_G	1.161	1.00
40_I	185_H	1.160	1.00
68_K	78_Y	1.159	1.00
14_L	226_A	1.158	1.00
138_A	149_I	1.155	1.00
217_E	222_N	1.149	1.00
93_G	300_F	1.147	1.00
59_F	72_M	1.145	1.00
65_F	381_P	1.138	1.00
419_F	423_T	1.136	1.00
173_S	176_L	1.129	1.00
424_L	427_L	1.119	1.00
163_G	167_I	1.118	1.00
389_N	393_F	1.112	1.00
35_A	41_S	1.108	1.00
29_M	106_S	1.102	1.00
169_W	173_S	1.096	1.00
63_G	75_Y	1.095	1.00
78_Y	378_A	1.094	1.00
8_K	217_E	1.087	1.00
324_Q	327_L	1.079	1.00
61_K	64_M	1.074	1.00
390_F	393_F	1.073	1.00
410_A	414_G	1.070	1.00
17_L	212_N	1.070	1.00
126_L	130_G	1.067	1.00
316_V	320_D	1.065	1.00
130_G	134_I	1.062	1.00
188_F	191_A	1.061	1.00
18_T	209_A	1.057	1.00
305_D	314_S	1.056	1.00
86_F	90_Y	1.056	1.00
411_M	415_S	1.051	1.00
185_H	188_F	1.047	1.00
73_G	302_S	1.046	1.00
395_G	399_S	1.042	1.00
19_M	233_G	1.040	1.00
414_G	418_T	1.037	1.00
150_S	290_L	1.034	1.00
170_F	175_T	1.032	1.00
371_L	392_A	1.028	1.00
149_I	153_T	1.017	1.00
76_A	84_G	1.017	1.00
108_V	127_A	1.016	1.00
400_F	404_Y	1.011	1.00
412_L	415_S	1.009	1.00
257_S	260_P	1.007	1.00
193_G	401_Y	1.003	1.00
81_G	85_N	1.003	1.00
148_Q	152_I	1.003	1.00
136_T	140_F	1.002	1.00
411_M	414_G	1.001	1.00
133_W	137_V	0.995	1.00
19_M	234_A	0.995	1.00
170_F	174_P	0.995	1.00
412_L	416_I	0.994	1.00
413_Y	416_I	0.993	1.00
162_V	166_I	0.991	1.00
46_L	239_I	0.990	1.00
189_F	192_V	0.990	1.00
259_A	263_L	0.983	1.00
183_P	186_A	0.976	1.00
385_A	389_N	0.974	1.00
376_K	389_N	0.973	1.00
396_A	400_F	0.972	1.00
111_G	115_L	0.970	1.00
368_M	396_A	0.968	1.00
331_I	335_G	0.967	1.00
248_I	264_A	0.966	1.00
134_I	286_C	0.964	1.00
140_F	321_A	0.959	1.00
143_A	294_F	0.958	1.00
392_A	396_A	0.957	1.00
372_V	389_N	0.955	1.00
213_T	223_V	0.953	1.00
54_A	391_V	0.950	1.00
365_I	399_S	0.947	1.00
250_P	267_Q	0.945	1.00
385_A	392_A	0.931	1.00
365_I	369_A	0.930	1.00
42_I	246_A	0.928	1.00
424_L	428_V	0.926	1.00
207_E	211_A	0.924	1.00
111_G	282_V	0.922	1.00
140_F	317_T	0.919	1.00
165_C	244_V	0.918	1.00
358_V	414_G	0.909	1.00
108_V	128_T	0.908	1.00
204_L	360_N	0.905	1.00
251_N	254_L	0.905	1.00
404_Y	408_E	0.904	1.00
153_T	287_G	0.904	1.00
235_A	239_I	0.903	1.00
421_G	425_Y	0.900	1.00
293_Q	330_V	0.897	1.00
164_L	265_F	0.895	1.00
70_G	74_G	0.895	1.00
229_G	233_G	0.893	1.00
387_V	390_F	0.881	1.00
165_C	169_W	0.873	1.00
43_I	192_V	0.873	1.00
102_A	201_W	0.871	1.00
157_V	284_S	0.870	1.00
70_G	73_G	0.866	1.00
189_F	193_G	0.865	1.00
16_I	151_S	0.860	1.00
158_I	237_I	0.860	1.00
243_N	247_G	0.859	1.00
49_A	203_F	0.852	1.00
330_V	334_S	0.850	1.00
270_T	273_V	0.849	1.00
135_C	290_L	0.847	1.00
90_Y	309_F	0.846	1.00
102_A	353_V	0.845	1.00
77_E	306_E	0.843	1.00
107_A	286_C	0.842	1.00
62_C	371_L	0.842	1.00
11_V	226_A	0.841	1.00
208_S	295_T	0.840	1.00
416_I	419_F	0.834	1.00
13_Q	148_Q	0.832	1.00
384_K	389_N	0.832	1.00
372_V	392_A	0.832	1.00
8_K	144_R	0.828	1.00
84_G	366_L	0.828	1.00
410_A	413_Y	0.824	1.00
317_T	320_D	0.822	1.00
309_F	313_F	0.821	1.00
127_A	130_G	0.821	1.00
98_I	101_V	0.820	1.00
392_A	406_S	0.813	1.00
137_V	140_F	0.810	1.00
403_L	406_S	0.807	1.00
53_M	57_W	0.805	1.00
194_S	198_M	0.804	1.00
172_F	175_T	0.800	1.00
389_N	392_A	0.799	1.00
385_A	391_V	0.796	1.00
83_S	87_M	0.796	1.00
83_S	422_W	0.794	1.00
313_F	324_Q	0.792	1.00
414_G	417_V	0.792	1.00
23_M	26_G	0.792	1.00
55_L	399_S	0.789	1.00
169_W	240_V	0.788	1.00
425_Y	429_S	0.787	1.00
107_A	285_C	0.786	1.00
401_Y	404_Y	0.786	1.00
420_L	424_L	0.785	1.00
323_V	327_L	0.784	1.00
148_Q	151_S	0.779	1.00
22_M	230_G	0.779	1.00
112_T	124_I	0.778	1.00
53_M	228_L	0.778	1.00
411_M	424_L	0.775	1.00
15_T	226_A	0.771	1.00
386_K	389_N	0.770	1.00
132_L	337_A	0.765	1.00
417_V	424_L	0.764	1.00
12_V	151_S	0.764	1.00
410_A	421_G	0.757	1.00
135_C	293_Q	0.757	1.00
185_H	192_V	0.756	1.00
139_N	326_M	0.755	1.00
399_S	402_A	0.754	1.00
141_G	145_I	0.754	1.00
355_L	359_T	0.751	1.00
125_G	337_A	0.749	1.00
371_L	375_Q	0.748	1.00
57_W	391_V	0.747	1.00
54_A	58_A	0.746	1.00
174_P	177_Y	0.745	1.00
410_A	415_S	0.744	1.00
170_F	173_S	0.742	1.00
76_A	370_A	0.742	1.00
46_L	50_V	0.742	1.00
388_A	391_V	0.739	1.00
411_M	421_G	0.738	1.00
80_F	370_A	0.737	1.00
386_K	390_F	0.736	1.00
410_A	417_V	0.736	1.00
224_P	227_V	0.735	1.00
331_I	334_S	0.733	1.00
318_K	323_V	0.732	1.00
43_I	46_L	0.730	1.00
108_V	124_I	0.729	1.00
395_G	398_Y	0.727	1.00
97_L	101_V	0.724	1.00
426_G	429_S	0.723	1.00
147_G	151_S	0.722	1.00
298_Q	301_K	0.722	1.00
417_V	420_L	0.721	1.00
105_I	352_L	0.721	1.00
411_M	425_Y	0.719	1.00
92_Y	96_L	0.718	1.00
204_L	364_Y	0.716	1.00
62_C	75_Y	0.714	1.00
129_I	338_L	0.712	1.00
122_V	125_G	0.711	1.00
297_A	325_G	0.710	1.00
139_N	294_F	0.710	1.00
358_V	403_L	0.708	1.00
218_N	224_P	0.707	1.00
372_V	376_K	0.707	1.00
172_F	176_L	0.706	1.00
313_F	325_G	0.705	1.00
73_G	77_E	0.705	1.00
418_T	422_W	0.701	1.00
27_I	241_S	0.700	1.00
69_S	301_K	0.700	1.00
220_E	382_P	0.699	1.00
412_L	428_V	0.698	1.00
423_T	426_G	0.697	1.00
165_C	241_S	0.696	1.00
140_F	319_V	0.696	1.00
413_Y	417_V	0.694	1.00
271_P	275_K	0.691	1.00
43_I	47_V	0.690	1.00
214_D	301_K	0.689	1.00
293_Q	297_A	0.686	1.00
12_V	148_Q	0.686	1.00
39_T	246_A	0.686	1.00
99_A	356_A	0.685	1.00
312_I	328_T	0.685	1.00
8_K	143_A	0.684	1.00
387_V	392_A	0.683	1.00
52_S	206_L	0.683	1.00
42_I	46_L	0.680	1.00
322_P	325_G	0.677	1.00
370_A	374_I	0.674	1.00
383_S	386_K	0.674	1.00
15_T	18_T	0.673	1.00
108_V	111_G	0.671	1.00
21_N	291_G	0.670	1.00
99_A	102_A	0.670	1.00
420_L	423_T	0.669	1.00
348_Q	351_V	0.669	1.00
415_S	418_T	0.668	1.00
378_A	381_P	0.668	1.00
97_L	332_I	0.668	1.00
388_A	393_F	0.667	1.00
54_A	395_G	0.666	1.00
111_G	131_V	0.665	1.00
23_M	157_V	0.665	1.00
63_G	223_V	0.664	1.00
8_K	12_V	0.662	1.00
304_S	313_F	0.661	1.00
79_A	373_I	0.660	1.00
260_P	264_A	0.659	1.00
215_V	316_V	0.659	1.00
425_Y	428_V	0.655	1.00
73_G	89_N	0.650	1.00
233_G	237_I	0.649	1.00
95_S	360_N	0.649	1.00
145_I	148_Q	0.648	1.00
29_M	32_T	0.647	1.00
33_K	350_N	0.645	1.00
172_F	244_V	0.645	1.00
59_F	367_S	0.645	1.00
411_M	418_T	0.644	1.00
173_S	177_Y	0.643	1.00
65_F	379_N	0.640	1.00
27_I	30_L	0.638	1.00
241_S	261_F	0.637	1.00
131_V	289_L	0.637	1.00
415_S	422_W	0.636	1.00
215_V	322_P	0.635	1.00
107_A	111_G	0.635	1.00
56_A	206_L	0.633	1.00
45_W	202_A	0.633	1.00
135_C	286_C	0.633	1.00
79_A	374_I	0.631	1.00
20_V	154_V	0.630	1.00
374_I	378_A	0.629	1.00
397_M	400_F	0.629	1.00
58_A	385_A	0.628	1.00
97_L	329_I	0.628	1.00
284_S	287_G	0.627	1.00
41_S	242_T	0.625	1.00
417_V	425_Y	0.625	1.00
81_G	429_S	0.624	1.00
229_G	232_L	0.623	1.00
359_T	363_P	0.623	1.00
23_M	28_I	0.623	1.00
133_W	136_T	0.622	1.00
219_P	222_N	0.622	1.00
33_K	36_E	0.621	1.00
27_I	31_P	0.621	1.00
34_L	37_V	0.621	1.00
106_S	110_Y	0.620	1.00
60_A	64_M	0.617	1.00
393_F	396_A	0.616	1.00
300_F	328_T	0.615	1.00
298_Q	316_V	0.615	1.00
140_F	326_M	0.613	1.00
19_M	22_M	0.613	1.00
383_S	389_N	0.611	1.00
104_A	108_V	0.610	1.00
42_I	239_I	0.608	1.00
136_T	293_Q	0.608	1.00
421_G	426_G	0.606	1.00
412_L	425_Y	0.605	1.00
72_M	207_E	0.603	1.00
167_I	171_W	0.602	1.00
31_P	242_T	0.602	1.00
103_I	289_L	0.602	1.00
404_Y	407_G	0.601	1.00
143_A	212_N	0.601	1.00
411_M	417_V	0.600	1.00
260_P	265_F	0.599	1.00
216_V	223_V	0.599	1.00
276_V	280_L	0.598	1.00
414_G	423_T	0.598	1.00
125_G	128_T	0.597	1.00
132_L	334_S	0.597	1.00
113_E	278_M	0.597	1.00
19_M	154_V	0.595	1.00
417_V	422_W	0.594	1.00
23_M	237_I	0.593	1.00
233_G	236_V	0.592	1.00
350_N	353_V	0.592	1.00
372_V	396_A	0.591	1.00
73_G	85_N	0.591	1.00
410_A	425_Y	0.590	1.00
414_G	419_F	0.590	1.00
58_A	395_G	0.590	1.00
399_S	403_L	0.589	1.00
114_L	279_A	0.589	1.00
259_A	262_G	0.588	1.00
156_G	280_L	0.588	1.00
142_G	145_I	0.588	1.00
63_G	210_C	0.587	1.00
402_A	407_G	0.585	1.00
91_T	363_P	0.585	1.00
411_M	428_V	0.584	1.00
12_V	15_T	0.584	1.00
296_I	300_F	0.583	1.00
211_A	295_T	0.583	1.00
241_S	245_I	0.582	1.00
61_K	65_F	0.581	1.00
402_A	406_S	0.581	1.00
56_A	60_A	0.581	1.00
398_Y	402_A	0.580	1.00
244_V	247_G	0.579	1.00
416_I	427_L	0.578	1.00
160_P	276_V	0.578	1.00
91_T	362_I	0.577	1.00
204_L	207_E	0.576	1.00
419_F	422_W	0.576	1.00
416_I	421_G	0.576	1.00
62_C	79_A	0.576	1.00
269_F	272_E	0.575	1.00
240_V	244_V	0.575	1.00
412_L	419_F	0.574	1.00
265_F	269_F	0.573	1.00
101_V	352_L	0.573	1.00
96_L	292_W	0.570	1.00
98_I	355_L	0.569	1.00
24_G	238_Y	0.569	1.00
47_V	196_I	0.568	1.00
103_I	106_S	0.568	1.00
328_T	332_I	0.566	1.00
145_I	149_I	0.566	1.00
39_T	251_N	0.566	1.00
147_G	290_L	0.565	1.00
48_T	203_F	0.563	1.00
14_L	212_N	0.561	1.00
210_C	227_V	0.561	1.00
298_Q	322_P	0.560	1.00
110_Y	281_M	0.560	1.00
375_Q	388_A	0.559	1.00
110_Y	262_G	0.558	1.00
349_F	353_V	0.558	1.00
191_A	194_S	0.558	1.00
48_T	200_L	0.553	1.00
31_P	34_L	0.553	1.00
416_I	423_T	0.552	1.00
223_V	227_V	0.551	1.00
72_M	211_A	0.550	1.00
167_I	269_F	0.550	1.00
335_G	338_L	0.549	1.00
361_I	399_S	0.548	1.00
421_G	429_S	0.547	1.00
365_I	403_L	0.546	1.00
25_S	201_W	0.546	1.00
159_I	162_V	0.544	1.00
413_Y	425_Y	0.544	1.00
380_V	384_K	0.538	1.00
24_G	31_P	0.535	1.00
156_G	160_P	0.535	1.00
412_L	417_V	0.534	1.00
209_A	223_V	0.534	1.00
39_T	42_I	0.534	1.00
193_G	405_S	0.534	1.00
30_L	353_V	0.533	1.00
422_W	425_Y	0.532	1.00
7_N	217_E	0.531	1.00
42_I	45_W	0.531	1.00
133_W	327_L	0.530	1.00
151_S	155_W	0.530	1.00
34_L	199_T	0.529	1.00
131_V	286_C	0.528	1.00
219_P	223_V	0.528	1.00
216_V	226_A	0.527	1.00
413_Y	419_F	0.526	1.00
265_F	270_T	0.526	1.00
200_L	402_A	0.526	1.00
424_L	429_S	0.525	1.00
18_T	22_M	0.525	1.00
414_G	428_V	0.523	1.00
410_A	426_G	0.523	1.00
204_L	356_A	0.522	1.00
392_A	399_S	0.521	1.00
272_E	275_K	0.521	1.00
21_N	292_W	0.521	1.00
134_I	138_A	0.520	1.00
91_T	95_S	0.520	1.00
154_V	157_V	0.520	1.00
184_H	187_P	0.519	1.00
316_V	319_V	0.518	1.00
146_T	294_F	0.518	1.00
279_A	283_M	0.517	1.00
418_T	421_G	0.516	1.00
29_M	33_K	0.516	1.00
114_L	282_V	0.515	1.00
44_S	192_V	0.514	1.00
76_A	85_N	0.513	1.00
171_W	268_M	0.513	1.00
415_S	421_G	0.512	1.00
265_F	273_V	0.511	1.00
45_W	242_T	0.511	1.00
245_I	261_F	0.510	1.00
312_I	316_V	0.509	1.00
18_T	226_A	0.508	1.00
24_G	28_I	0.507	1.00
122_V	127_A	0.507	1.00
293_Q	326_M	0.507	1.00
172_F	248_I	0.506	1.00
114_L	278_M	0.506	1.00
87_M	91_T	0.504	1.00
410_A	419_F	0.504	1.00
88_A	363_P	0.503	1.00
21_N	208_S	0.503	1.00
396_A	399_S	0.503	1.00
300_F	304_S	0.503	1.00
55_L	207_E	0.503	1.00
413_Y	421_G	0.502	1.00
233_G	240_V	0.502	1.00
150_S	287_G	0.501	1.00
10_G	144_R	0.501	1.00
60_A	227_V	0.500	1.00
80_F	85_N	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.959	100	0.221	Contact Map
3giaA	1	0.959	100	0.312	Contact Map
4djkA	2	0.9294	100	0.331	Contact Map
3dh4A	3	0.9339	98.7	0.862	Contact Map
2jlnA	1	0.918	98.7	0.864	Contact Map
2xq2A	2	0.9317	98.7	0.865	Contact Map
4wgvA	2	0.8405	98.1	0.886	Contact Map
2a65A	2	0.9476	98	0.889	Contact Map
4us3A	1	0.8815	97	0.908	Contact Map
4xp4A	1	0.9544	96.8	0.91	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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