CADB - ECOLI - GREMLIN Contacts

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CADB - Probable cadaverine/lysine antiporter

UniProt:	P0AAE8	Sequences: MSSAKKIGLFACTGVVAGNMMGSGIALLPANLASIGGIAIWGWIISIIGAMSLAYVYARLATKNPQQGGPIAYAGEISPAFGFQTGVLYYHANWIGNLAIGITAVSYLSTFFPVLNDPVPAGIACIAIVWVFTFVNMLGGTWVSRLTTIGLVLVLIPVVMTAIVGWHWFDAATYAANWNTADTTDGHAIIKSILLCLWAFVGVESAAVSTGMVKNPKRTVPLATMLGTGLAGIVYIAATQVLSGMYPSSVMAASGAPFAISASTILGNWAAPLVSAFTAFACLTSLGSWMMLVGQAGVRAANDGNFPKVYGEVDSNGIPKKGLLLAAVKMTALMILITLMNSAGGKASDLFGELTGIAVLLTMLPYFYSCVDLIRFEGVNIRNFVSLICSVLGCVFCFIALMGASSFELAGTFIVSLIILMFYARKMHERQSHSMDNHTASNAH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10132
Length:	444 (411)
Sequences:	24644 (15998)
Seq/√Len:	789.1

ECOLI - CADB ADIC POTE PUUP AROP PROY ARCD PLAP LYSP ANSP MMUP FRLA YIFK YJEH PHEP YGJI GABP CYCA YBAT GADC YCAM YJEM TNAB
BACSU - HUTM ARCD YTNA ASPP YBGF GABP YBXG ROCC YBEC YHDG YCGH YECA STET YDGF YVBW ROCE YFNA AAPA YDAO GERBB GERAB YNDE GERKB YFKT
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97U05 Q97XM0 Q7LXI7 Q97WS3 Q97U33 Q97X49 Q97ZB5 Q97Z63 Q97VR4 Q97WD4 Q97Y76 Q97VA6 Q97VA8 Q97YN3 Q97YX9 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
309_V	321_K	4.398	1.00
133_T	327_A	4.389	1.00
47_I	232_G	3.255	1.00
312_E	321_K	3.091	1.00
218_R	222_L	2.967	1.00
8_G	214_K	2.891	1.00
375_R	379_V	2.842	1.00
367_F	394_C	2.833	1.00
71_I	303_D	2.704	1.00
213_V	219_T	2.687	1.00
215_N	218_R	2.676	1.00
86_G	300_A	2.653	1.00
314_D	320_K	2.649	1.00
165_G	241_V	2.591	1.00
301_A	311_G	2.527	1.00
309_V	312_E	2.499	1.00
163_I	167_H	2.383	1.00
13_T	226_L	2.375	1.00
269_W	273_L	2.371	1.00
211_G	302_N	2.308	1.00
9_L	226_L	2.298	1.00
212_M	295_Q	2.244	1.00
260_I	263_S	2.221	1.00
298_V	302_N	2.174	1.00
370_C	393_G	2.174	1.00
9_L	219_T	2.162	1.00
75_G	82_G	2.138	1.00
391_V	395_V	2.124	1.00
421_M	425_R	2.122	1.00
324_L	328_V	2.111	1.00
134_F	138_L	2.095	1.00
379_V	383_N	2.075	1.00
12_C	213_V	2.065	1.00
141_T	145_R	2.050	1.00
9_L	13_T	2.030	1.00
77_I	375_R	2.016	1.00
222_L	226_L	2.013	1.00
137_M	320_K	2.013	1.00
250_V	264_T	1.991	1.00
133_T	323_L	1.986	1.00
75_G	79_P	1.955	1.00
126_I	335_I	1.943	1.00
152_V	156_I	1.937	1.00
90_Y	326_A	1.937	1.00
8_G	11_A	1.920	1.00
56_V	370_C	1.914	1.00
78_S	81_F	1.912	1.00
310_Y	325_L	1.898	1.00
260_I	264_T	1.892	1.00
304_G	308_K	1.885	1.00
48_I	52_S	1.870	1.00
386_S	390_S	1.869	1.00
395_V	399_I	1.857	1.00
126_I	332_A	1.838	1.00
77_I	371_V	1.828	1.00
59_R	377_E	1.819	1.00
247_P	250_V	1.817	1.00
388_I	392_L	1.815	1.00
338_T	341_N	1.799	1.00
130_W	327_A	1.785	1.00
32_L	39_A	1.742	1.00
11_A	148_T	1.741	1.00
136_N	287_G	1.738	1.00
215_N	219_T	1.734	1.00
375_R	378_G	1.726	1.00
87_V	419_I	1.724	1.00
74_A	85_T	1.709	1.00
225_M	229_G	1.671	1.00
16_V	227_G	1.655	1.00
380_N	383_N	1.649	1.00
42_G	192_S	1.633	1.00
101_G	286_L	1.608	1.00
49_G	396_F	1.601	1.00
314_D	318_I	1.601	1.00
415_V	419_I	1.595	1.00
85_T	368_Y	1.586	1.00
156_I	160_M	1.581	1.00
108_L	124_A	1.570	1.00
13_T	230_L	1.570	1.00
377_E	381_I	1.565	1.00
177_N	180_T	1.562	1.00
385_V	389_C	1.556	1.00
413_F	417_L	1.552	1.00
137_M	324_L	1.535	1.00
387_L	391_V	1.530	1.00
321_K	325_L	1.516	1.00
157_P	277_F	1.513	1.00
254_S	260_I	1.512	1.00
298_V	313_V	1.510	1.00
263_S	271_A	1.501	1.00
371_V	394_C	1.500	1.00
7_I	11_A	1.490	1.00
229_G	233_I	1.489	1.00
420_L	424_A	1.484	1.00
378_G	381_I	1.460	1.00
371_V	375_R	1.457	1.00
101_G	129_V	1.454	1.00
209_S	291_M	1.450	1.00
215_N	222_L	1.449	1.00
297_G	322_G	1.449	1.00
293_V	326_A	1.447	1.00
399_I	403_G	1.446	1.00
46_S	196_C	1.444	1.00
104_A	128_I	1.444	1.00
4_A	317_G	1.428	1.00
308_K	311_G	1.425	1.00
74_A	368_Y	1.424	1.00
104_A	279_A	1.417	1.00
166_W	241_V	1.412	1.00
126_I	130_W	1.408	1.00
54_A	228_T	1.407	1.00
48_I	392_L	1.396	1.00
406_S	409_L	1.387	1.00
272_P	276_A	1.386	1.00
133_T	324_L	1.384	1.00
64_N	76_E	1.377	1.00
120_P	123_I	1.365	1.00
233_I	237_A	1.363	1.00
176_A	180_T	1.357	1.00
129_V	331_T	1.354	1.00
308_K	312_E	1.353	1.00
77_I	81_F	1.346	1.00
52_S	392_L	1.345	1.00
67_Q	211_G	1.343	1.00
54_A	224_T	1.341	1.00
409_L	412_T	1.338	1.00
129_V	327_A	1.337	1.00
385_V	388_I	1.335	1.00
219_T	222_L	1.333	1.00
169_F	244_G	1.326	1.00
312_E	320_K	1.324	1.00
216_P	221_P	1.305	1.00
11_A	144_S	1.303	1.00
266_L	270_A	1.298	1.00
155_L	159_V	1.297	1.00
162_A	237_A	1.292	1.00
414_I	418_I	1.288	1.00
40_I	240_Q	1.287	1.00
294_G	323_L	1.285	1.00
7_I	12_C	1.279	1.00
170_D	173_T	1.266	1.00
132_F	286_L	1.256	1.00
100_I	285_S	1.248	1.00
331_T	334_M	1.241	1.00
169_F	172_A	1.240	1.00
406_S	410_A	1.233	1.00
55_Y	225_M	1.230	1.00
90_Y	297_G	1.223	1.00
393_G	397_C	1.222	1.00
72_A	76_E	1.214	1.00
59_R	62_T	1.213	1.00
20_M	231_A	1.207	1.00
419_I	422_F	1.207	1.00
419_I	423_Y	1.206	1.00
263_S	268_N	1.206	1.00
9_L	222_L	1.206	1.00
10_F	14_G	1.205	1.00
122_G	126_I	1.198	1.00
397_C	400_A	1.198	1.00
385_V	390_S	1.196	1.00
53_L	370_C	1.194	1.00
165_G	245_M	1.191	1.00
422_F	425_R	1.188	1.00
80_A	426_K	1.185	1.00
27_L	103_T	1.183	1.00
56_V	390_S	1.177	1.00
321_K	324_L	1.173	1.00
297_G	306_F	1.170	1.00
7_I	144_S	1.160	1.00
63_K	383_N	1.160	1.00
254_S	257_P	1.155	1.00
388_I	391_V	1.152	1.00
135_V	146_L	1.151	1.00
57_Y	70_P	1.137	1.00
409_L	413_F	1.135	1.00
313_V	317_G	1.129	1.00
66_Q	72_A	1.129	1.00
161_T	165_G	1.129	1.00
302_N	311_G	1.128	1.00
83_F	87_V	1.125	1.00
160_M	164_V	1.124	1.00
398_F	402_M	1.123	1.00
412_T	416_S	1.122	1.00
105_V	124_A	1.121	1.00
367_F	398_F	1.115	1.00
125_C	335_I	1.110	1.00
97_N	331_T	1.107	1.00
214_K	219_T	1.106	1.00
411_G	414_I	1.104	1.00
417_L	421_M	1.103	1.00
61_A	73_Y	1.098	1.00
407_F	410_A	1.094	1.00
12_C	223_A	1.092	1.00
127_A	131_V	1.081	1.00
74_A	81_F	1.081	1.00
185_D	188_A	1.076	1.00
374_I	391_V	1.075	1.00
123_I	127_A	1.069	1.00
17_A	231_A	1.064	1.00
6_K	214_K	1.064	1.00
147_T	287_G	1.058	1.00
256_A	260_I	1.056	1.00
145_R	149_I	1.052	1.00
16_V	206_A	1.050	1.00
174_Y	244_G	1.049	1.00
15_V	209_S	1.044	1.00
133_T	137_M	1.039	1.00
407_F	411_G	1.035	1.00
332_A	335_I	1.033	1.00
17_A	230_L	1.027	1.00
401_L	404_A	1.024	1.00
33_A	39_A	1.020	1.00
146_L	150_G	1.019	1.00
384_F	387_L	1.012	1.00
422_F	426_K	1.010	1.00
21_M	24_G	1.004	1.00
178_W	183_T	0.996	1.00
140_G	291_M	0.994	1.00
393_G	396_F	0.991	1.00
247_P	264_T	0.990	1.00
66_Q	76_E	0.986	1.00
159_V	163_I	0.983	1.00
119_V	123_I	0.981	1.00
373_L	390_S	0.979	1.00
131_V	283_L	0.976	1.00
44_I	236_I	0.973	1.00
71_I	299_R	0.973	1.00
137_M	318_I	0.966	1.00
414_I	417_L	0.963	1.00
268_N	272_P	0.963	1.00
394_C	398_F	0.962	1.00
161_T	262_A	0.957	1.00
390_S	394_C	0.955	1.00
108_L	112_F	0.954	1.00
377_E	380_N	0.946	1.00
410_A	413_F	0.943	1.00
190_I	399_I	0.943	1.00
210_T	220_V	0.938	1.00
150_G	284_T	0.930	1.00
402_M	405_S	0.929	1.00
374_I	387_L	0.928	1.00
130_W	134_F	0.928	1.00
240_Q	244_G	0.927	1.00
6_K	141_T	0.924	1.00
162_A	241_V	0.923	1.00
99_A	198_W	0.923	1.00
385_V	404_A	0.914	1.00
201_V	362_T	0.913	1.00
132_F	287_G	0.913	1.00
387_L	390_S	0.912	1.00
290_M	327_A	0.911	1.00
40_I	243_S	0.909	1.00
14_G	148_T	0.908	1.00
176_A	179_N	0.908	1.00
137_M	314_D	0.907	1.00
378_G	387_L	0.905	1.00
245_M	261_S	0.903	1.00
410_A	414_I	0.903	1.00
105_V	125_C	0.902	1.00
226_L	230_L	0.901	1.00
387_L	404_A	0.899	1.00
360_L	412_T	0.899	1.00
386_S	389_C	0.898	1.00
155_L	234_V	0.896	1.00
204_E	208_V	0.895	1.00
367_F	371_V	0.892	1.00
186_G	189_I	0.891	1.00
174_Y	177_N	0.885	1.00
162_A	166_W	0.882	1.00
179_N	183_T	0.882	1.00
87_V	306_F	0.881	1.00
68_G	72_A	0.879	1.00
379_V	382_R	0.879	1.00
76_E	380_N	0.876	1.00
130_W	332_A	0.876	1.00
312_E	315_S	0.874	1.00
232_G	236_I	0.874	1.00
134_F	137_M	0.869	1.00
390_S	404_A	0.866	1.00
154_V	281_A	0.861	1.00
418_I	422_F	0.860	1.00
367_F	397_C	0.860	1.00
205_S	292_L	0.856	1.00
306_F	310_Y	0.854	1.00
124_A	127_A	0.853	1.00
52_S	389_C	0.851	1.00
41_W	45_I	0.849	1.00
378_G	382_R	0.848	1.00
178_W	182_D	0.848	1.00
191_K	195_L	0.845	1.00
384_F	388_I	0.844	1.00
406_S	419_I	0.844	1.00
99_A	355_T	0.843	1.00
75_G	303_D	0.841	1.00
399_I	402_M	0.841	1.00
9_L	223_A	0.840	1.00
310_Y	321_K	0.834	1.00
320_K	324_L	0.832	1.00
68_G	71_I	0.831	1.00
370_C	394_C	0.831	1.00
11_A	145_R	0.826	1.00
80_A	84_Q	0.822	1.00
51_M	55_Y	0.819	1.00
334_M	338_T	0.819	1.00
145_R	148_T	0.818	1.00
315_S	320_K	0.817	1.00
400_A	404_A	0.816	1.00
166_W	170_D	0.811	1.00
80_A	420_L	0.807	1.00
47_I	200_F	0.807	1.00
186_G	190_I	0.805	1.00
44_I	48_I	0.803	1.00
390_S	397_C	0.802	1.00
174_Y	178_W	0.798	1.00
41_W	189_I	0.797	1.00
418_I	421_M	0.797	1.00
104_A	283_L	0.796	1.00
384_F	390_S	0.796	1.00
167_H	171_A	0.796	1.00
408_E	411_G	0.796	1.00
108_L	279_A	0.790	1.00
357_I	361_L	0.788	1.00
60_L	373_L	0.784	1.00
408_E	412_T	0.780	1.00
166_W	237_A	0.778	1.00
167_H	170_D	0.778	1.00
78_S	427_M	0.777	1.00
238_A	258_F	0.777	1.00
178_W	181_A	0.776	1.00
331_T	335_I	0.774	1.00
177_N	182_D	0.774	1.00
51_M	225_M	0.767	1.00
104_A	282_C	0.766	1.00
221_P	224_T	0.766	1.00
81_F	368_Y	0.762	1.00
22_G	26_A	0.762	1.00
52_S	56_V	0.762	1.00
393_G	404_A	0.756	1.00
10_F	145_R	0.756	1.00
138_L	142_W	0.755	1.00
63_K	381_I	0.755	1.00
267_G	270_A	0.753	1.00
10_F	148_T	0.753	1.00
13_T	16_V	0.752	1.00
96_G	358_A	0.751	1.00
384_F	404_A	0.751	1.00
413_F	419_I	0.751	1.00
397_C	404_A	0.749	1.00
177_N	183_T	0.744	1.00
132_F	290_M	0.743	1.00
176_A	181_A	0.743	1.00
294_G	322_G	0.736	1.00
256_A	259_A	0.733	1.00
53_L	397_C	0.733	1.00
162_A	238_A	0.733	1.00
60_L	73_Y	0.728	1.00
407_F	412_T	0.726	1.00
174_Y	179_N	0.726	1.00
295_Q	298_V	0.723	1.00
167_H	172_A	0.721	1.00
415_V	418_I	0.721	1.00
201_V	366_Y	0.720	1.00
71_I	75_G	0.719	1.00
13_T	223_A	0.716	1.00
144_S	148_T	0.714	1.00
237_A	241_V	0.713	1.00
372_D	376_F	0.709	1.00
176_A	183_T	0.709	1.00
395_V	398_F	0.709	1.00
6_K	140_G	0.708	1.00
29_P	239_T	0.706	1.00
78_S	82_G	0.705	1.00
416_S	419_I	0.704	1.00
136_N	323_L	0.704	1.00
390_S	405_S	0.703	1.00
290_M	294_G	0.701	1.00
74_A	372_D	0.699	1.00
21_M	26_A	0.698	1.00
67_Q	298_V	0.697	1.00
215_N	221_P	0.697	1.00
50_A	203_V	0.695	1.00
137_M	323_L	0.693	1.00
397_C	401_L	0.693	1.00
310_Y	322_G	0.692	1.00
20_M	227_G	0.692	1.00
211_G	298_V	0.692	1.00
39_A	239_T	0.690	1.00
400_A	403_G	0.687	1.00
179_N	182_D	0.687	1.00
108_L	128_I	0.687	1.00
109_S	113_P	0.687	1.00
301_A	310_Y	0.686	1.00
421_M	424_A	0.686	1.00
57_Y	369_S	0.685	1.00
80_A	423_Y	0.685	1.00
132_F	283_L	0.684	1.00
413_F	416_S	0.683	1.00
332_A	336_L	0.682	1.00
101_G	105_V	0.682	1.00
21_M	154_V	0.681	1.00
25_I	238_A	0.677	1.00
153_L	277_F	0.676	1.00
164_V	168_W	0.671	1.00
309_V	325_L	0.670	1.00
43_W	199_A	0.668	1.00
316_N	320_K	0.666	1.00
133_T	290_M	0.666	1.00
94_W	326_A	0.665	1.00
35_I	191_K	0.665	1.00
102_I	354_L	0.664	1.00
226_L	229_G	0.664	1.00
88_L	365_P	0.664	1.00
100_I	103_T	0.663	1.00
269_W	272_P	0.663	1.00
164_V	266_L	0.663	1.00
59_R	63_K	0.662	1.00
361_L	365_P	0.662	1.00
71_I	86_G	0.659	1.00
32_L	36_G	0.657	1.00
41_W	44_I	0.656	1.00
58_A	62_T	0.653	1.00
94_W	329_K	0.651	1.00
262_A	267_G	0.651	1.00
314_D	317_G	0.648	1.00
77_I	82_G	0.648	1.00
401_L	405_S	0.645	1.00
98_L	354_L	0.645	1.00
38_I	243_S	0.645	1.00
328_V	333_L	0.642	1.00
230_L	234_V	0.642	1.00
297_G	325_L	0.641	1.00
142_W	145_R	0.640	1.00
18_G	151_L	0.639	1.00
384_F	389_C	0.638	1.00
81_F	84_Q	0.638	1.00
31_N	352_G	0.636	1.00
111_F	275_S	0.636	1.00
31_N	34_S	0.635	1.00
335_I	338_T	0.635	1.00
40_I	44_I	0.634	1.00
207_A	224_T	0.634	1.00
386_S	401_L	0.633	1.00
262_A	270_A	0.633	1.00
6_K	10_F	0.633	1.00
394_C	397_C	0.631	1.00
415_V	422_F	0.630	1.00
109_S	121_A	0.630	1.00
136_N	291_M	0.630	1.00
406_S	413_F	0.629	1.00
45_I	193_I	0.628	1.00
19_N	289_W	0.627	1.00
95_I	357_I	0.626	1.00
377_E	382_R	0.626	1.00
386_S	393_G	0.625	1.00
325_L	329_K	0.625	1.00
35_I	38_I	0.625	1.00
139_G	142_W	0.625	1.00
416_S	420_L	0.624	1.00
212_M	313_V	0.624	1.00
89_Y	93_N	0.623	1.00
19_N	288_S	0.623	1.00
128_I	286_L	0.622	1.00
96_G	99_A	0.621	1.00
138_L	316_N	0.621	1.00
61_A	207_A	0.619	1.00
16_V	20_M	0.619	1.00
293_V	297_G	0.617	1.00
212_M	319_P	0.617	1.00
54_A	203_V	0.616	1.00
373_L	377_E	0.616	1.00
396_F	400_A	0.616	1.00
130_W	133_T	0.615	1.00
54_A	58_A	0.614	1.00
406_S	412_T	0.612	1.00
248_S	251_M	0.611	1.00
105_V	108_L	0.610	1.00
61_A	220_V	0.609	1.00
208_V	292_L	0.608	1.00
216_P	219_T	0.608	1.00
77_I	372_D	0.607	1.00
220_V	224_T	0.606	1.00
112_F	118_P	0.606	1.00
390_S	400_A	0.606	1.00
70_P	204_E	0.604	1.00
230_L	233_I	0.604	1.00
42_G	189_I	0.603	1.00
169_F	173_T	0.603	1.00
92_A	362_T	0.601	1.00
103_T	107_Y	0.601	1.00
396_F	399_I	0.601	1.00
105_V	121_A	0.599	1.00
31_N	35_I	0.599	1.00
201_V	204_E	0.598	1.00
143_V	291_M	0.597	1.00
176_A	182_D	0.592	1.00
360_L	401_L	0.592	1.00
408_E	415_V	0.590	1.00
71_I	82_G	0.590	1.00
93_N	289_W	0.589	1.00
374_I	378_G	0.588	1.00
113_P	118_P	0.587	1.00
257_P	262_A	0.587	1.00
412_T	423_Y	0.586	1.00
52_S	393_G	0.586	1.00
238_A	242_L	0.586	1.00
180_T	183_T	0.586	1.00
107_Y	278_T	0.584	1.00
169_F	245_M	0.583	1.00
386_S	404_A	0.579	1.00
21_M	234_V	0.579	1.00
188_A	191_K	0.578	1.00
412_T	422_F	0.577	1.00
111_F	276_A	0.576	1.00
43_W	239_T	0.574	1.00
140_G	209_S	0.571	1.00
122_G	125_C	0.571	1.00
391_V	394_C	0.569	1.00
295_Q	313_V	0.569	1.00
334_M	341_N	0.569	1.00
406_S	416_S	0.569	1.00
19_N	205_S	0.568	1.00
100_I	286_L	0.567	1.00
157_P	273_L	0.563	1.00
213_V	220_V	0.563	1.00
63_K	376_F	0.562	1.00
142_W	146_L	0.561	1.00
407_F	419_I	0.561	1.00
389_C	403_G	0.561	1.00
352_G	355_T	0.560	1.00
8_G	141_T	0.559	1.00
70_P	208_V	0.558	1.00
127_A	130_W	0.556	1.00
46_S	200_F	0.556	1.00
46_S	197_L	0.555	1.00
281_A	284_T	0.555	1.00
319_P	322_G	0.555	1.00
190_I	403_G	0.555	1.00
144_S	287_G	0.554	1.00
38_I	248_S	0.554	1.00
389_C	393_G	0.554	1.00
175_A	179_N	0.554	1.00
362_T	365_P	0.552	1.00
110_T	113_P	0.552	1.00
378_G	383_N	0.551	1.00
17_A	151_L	0.551	1.00
276_A	280_F	0.551	1.00
262_A	266_L	0.551	1.00
98_L	101_G	0.548	1.00
10_F	13_T	0.548	1.00
156_I	159_V	0.547	1.00
148_T	152_V	0.547	1.00
59_R	384_F	0.546	1.00
295_Q	319_P	0.546	1.00
151_L	154_V	0.546	1.00
394_C	405_S	0.546	1.00
12_C	209_S	0.545	1.00
401_L	409_L	0.544	1.00
230_L	237_A	0.544	1.00
164_V	267_G	0.543	1.00
242_L	258_F	0.541	1.00
177_N	181_A	0.541	1.00
386_S	391_V	0.540	1.00
400_A	405_S	0.538	1.00
409_L	416_S	0.538	1.00
241_V	244_G	0.537	1.00
159_V	162_A	0.537	1.00
129_V	335_I	0.535	1.00
392_L	396_F	0.535	1.00
218_R	221_P	0.535	1.00
119_V	122_G	0.530	1.00
327_A	332_A	0.529	1.00
32_L	192_S	0.529	1.00
415_V	423_Y	0.527	1.00
110_T	275_S	0.526	1.00
273_L	277_F	0.525	1.00
309_V	313_V	0.525	1.00
23_S	198_W	0.524	1.00
40_I	236_I	0.523	1.00
408_E	419_I	0.523	1.00
128_I	132_F	0.522	1.00
217_K	222_L	0.521	1.00
286_L	289_W	0.521	1.00
100_I	282_C	0.519	1.00
336_L	339_L	0.519	1.00
320_K	323_L	0.519	1.00
92_A	95_I	0.518	1.00
201_V	358_A	0.515	1.00
390_S	393_G	0.515	1.00
394_C	404_A	0.515	1.00
29_P	33_A	0.514	1.00
69_G	207_A	0.513	1.00
28_L	355_T	0.513	1.00
5_K	214_K	0.513	1.00
25_I	158_V	0.513	1.00
74_A	82_G	0.513	1.00
107_Y	259_A	0.512	1.00
416_S	423_Y	0.512	1.00
377_E	386_S	0.510	1.00
351_F	355_T	0.510	1.00
365_P	369_S	0.509	1.00
410_A	415_V	0.507	1.00
393_G	400_A	0.506	1.00
128_I	283_L	0.506	1.00
208_V	296_A	0.505	1.00
391_V	401_L	0.505	1.00
53_L	204_E	0.505	1.00
149_I	153_L	0.505	1.00
82_G	86_G	0.504	1.00
32_L	196_C	0.504	1.00
85_T	365_P	0.502	1.00
213_V	223_A	0.502	1.00
66_Q	211_G	0.501	1.00
36_G	42_G	0.501	1.00
88_L	92_A	0.500	1.00
153_L	157_P	0.500	1.00
406_S	423_Y	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.9459	100	0.221	Contact Map
3giaA	1	0.9572	100	0.302	Contact Map
4djkA	2	0.9189	100	0.371	Contact Map
3dh4A	3	0.9347	99	0.847	Contact Map
2xq2A	2	0.9347	98.9	0.85	Contact Map
2jlnA	1	0.9167	98.7	0.86	Contact Map
2a65A	2	0.9189	97.2	0.904	Contact Map
4wgvA	2	0.8108	97.1	0.905	Contact Map
4xp4A	1	0.9482	96.4	0.913	Contact Map
4us3A	1	0.8739	94.8	0.922	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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