ARCD - ECOLI - GREMLIN Contacts

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ARCD - Putative arginine/ornithine antiporter

UniProt:	P0AAE5	Sequences: MEKKLGLSALTALVLSSMLGAGVFSLPQNMAAVASPAALLIGWGITGAGILLLAFAMLILTRIRPELDGGIFTYAREGFGELIGFCSAWGYWLCAVIANVSYLVIVFSALSFFTDTPELRLFGDGNTWQSIVGASALLWIVHFLILRGVQTAASINLVATLAKLLPLGLFVVLAMMMFKLDTFKLDFTGLALGVPVWEQVKNTMLITLWVFIGVEGAVVVSARARNKRDVGKATLLAVLSALGVYLLVTLLSLGVVARPELAEIRNPSMAGLMVEMMGPWGEIIIAAGLIVSVCGAYLSWTIMAAEVPFLAATHKAFPRIFARQNAQAAPSASLWLTNICVQICLVLIWLTGSDYNTLLTIASEMILVPYFLVGAFLLKIATRPLHKAVGVGACIYGLWLLYASGPMHLLLSVVLYAPGLLVFLYARKTHTHDNVLNRQEMVLIGMLLIASVPATWMLVG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13930
Length:	460 (406)
Sequences:	24651 (15798)
Seq/√Len:	784.1

ECOLI - ARCD ANSP POTE ADIC PUUP PROY FRLA AROP CADB PLAP YJEH MMUP YIFK LYSP GABP CYCA PHEP GADC YGJI YBAT YCAM YJEM
BACSU - ASPP GABP YBXG ROCC YBEC ARCD YTNA YBGF HUTM YHDG YCGH YDGF YVBW YECA ROCE YFNA AAPA STET YDAO GERBB YNDE GERAB GERKB
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97U05 Q7LXI7 Q97X49 Q97U33 Q97WS3 Q97XM0 Q97WD4 Q97Z63 Q97ZB5 Q97VR4 Q97VA8 Q97VA6 Q97Y76 Q97YN3 Q97YX9 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
142_H	338_N	4.346	1.00
320_I	332_A	4.254	1.00
47_G	242_L	3.149	1.00
323_R	332_A	3.088	1.00
228_R	232_K	3.025	1.00
6_G	225_R	2.914	1.00
59_I	381_A	2.765	1.00
72_F	314_H	2.727	1.00
224_A	229_D	2.712	1.00
88_A	311_A	2.643	1.00
325_N	331_S	2.615	1.00
312_A	322_A	2.530	1.00
174_A	251_L	2.458	1.00
135_S	342_Q	2.436	1.00
11_T	236_L	2.417	1.00
172_V	176_M	2.407	1.00
222_A	313_T	2.398	1.00
280_W	284_I	2.379	1.00
320_I	323_R	2.372	1.00
415_L	419_G	2.362	1.00
7_L	236_L	2.320	1.00
223_R	306_E	2.285	1.00
371_F	394_C	2.257	1.00
76_R	84_G	2.237	1.00
79_F	379_K	2.176	1.00
335_W	339_I	2.160	1.00
309_F	313_T	2.129	1.00
399_W	403_A	2.119	1.00
142_H	334_L	2.110	1.00
143_F	147_R	2.103	1.00
7_L	229_D	2.083	1.00
150_Q	154_S	2.051	1.00
7_L	11_T	2.045	1.00
139_W	342_Q	2.039	1.00
10_L	224_A	2.023	1.00
134_A	345_L	1.979	1.00
374_G	393_A	1.966	1.00
146_L	331_S	1.950	1.00
6_G	9_A	1.941	1.00
161_L	165_L	1.930	1.00
56_A	374_G	1.929	1.00
383_R	387_K	1.924	1.00
315_K	319_R	1.920	1.00
135_S	345_L	1.916	1.00
232_K	236_L	1.915	1.00
92_W	337_T	1.897	1.00
76_R	81_E	1.890	1.00
321_F	336_L	1.883	1.00
48_A	52_L	1.882	1.00
30_M	39_L	1.876	1.00
406_P	409_L	1.866	1.00
391_V	395_I	1.858	1.00
235_L	239_L	1.830	1.00
79_F	375_A	1.829	1.00
271_G	274_V	1.793	1.00
257_A	260_E	1.787	1.00
419_G	422_V	1.783	1.00
405_G	408_H	1.775	1.00
395_I	399_W	1.739	1.00
393_A	397_G	1.731	1.00
226_N	229_D	1.726	1.00
260_E	275_E	1.721	1.00
139_W	338_N	1.714	1.00
103_L	297_Y	1.693	1.00
9_A	157_L	1.685	1.00
390_G	393_A	1.672	1.00
145_I	298_L	1.669	1.00
388_A	392_G	1.663	1.00
421_L	425_Y	1.661	1.00
87_S	372_L	1.657	1.00
75_A	87_S	1.648	1.00
14_V	237_A	1.639	1.00
325_N	329_A	1.635	1.00
42_G	203_T	1.615	1.00
138_L	341_V	1.612	1.00
146_L	335_W	1.605	1.00
99_N	341_V	1.605	1.00
166_P	288_G	1.569	1.00
11_T	240_S	1.567	1.00
399_W	402_Y	1.555	1.00
165_L	169_L	1.554	1.00
89_W	419_G	1.553	1.00
129_Q	132_V	1.547	1.00
5_L	9_A	1.544	1.00
382_T	385_L	1.538	1.00
424_L	428_K	1.538	1.00
390_G	394_C	1.524	1.00
110_L	133_G	1.510	1.00
239_L	243_G	1.494	1.00
220_V	302_I	1.479	1.00
226_N	232_K	1.467	1.00
164_L	168_G	1.461	1.00
103_L	138_L	1.461	1.00
404_S	408_H	1.458	1.00
309_F	324_Q	1.453	1.00
375_A	379_K	1.450	1.00
308_P	333_S	1.447	1.00
46_T	207_T	1.432	1.00
68_D	222_A	1.429	1.00
332_A	336_L	1.426	1.00
54_A	238_V	1.425	1.00
80_G	83_I	1.424	1.00
413_V	417_A	1.397	1.00
142_H	335_W	1.394	1.00
37_A	193_G	1.386	1.00
75_A	372_L	1.386	1.00
175_M	251_L	1.381	1.00
319_R	323_R	1.379	1.00
138_L	338_N	1.372	1.00
304_A	337_T	1.372	1.00
106_V	290_I	1.370	1.00
243_G	247_L	1.365	1.00
319_R	322_A	1.354	1.00
390_G	402_Y	1.342	1.00
283_I	287_A	1.341	1.00
393_A	396_Y	1.336	1.00
128_W	132_V	1.334	1.00
323_R	331_S	1.331	1.00
79_F	83_I	1.330	1.00
397_G	400_L	1.321	1.00
305_A	334_L	1.320	1.00
229_D	232_K	1.310	1.00
25_S	105_I	1.307	1.00
264_I	271_G	1.303	1.00
106_V	137_L	1.296	1.00
274_V	282_E	1.294	1.00
9_A	153_A	1.293	1.00
53_L	374_G	1.288	1.00
390_G	397_G	1.277	1.00
64_R	77_E	1.276	1.00
171_V	247_L	1.271	1.00
135_S	139_W	1.261	1.00
82_L	426_A	1.259	1.00
54_A	234_T	1.258	1.00
78_G	376_F	1.253	1.00
5_L	10_L	1.251	1.00
375_A	394_C	1.248	1.00
40_L	250_L	1.247	1.00
308_P	317_F	1.245	1.00
7_L	232_K	1.236	1.00
102_Y	296_A	1.222	1.00
425_Y	429_T	1.221	1.00
55_F	235_L	1.219	1.00
49_G	396_Y	1.217	1.00
271_G	275_E	1.217	1.00
384_P	387_K	1.208	1.00
419_G	423_F	1.206	1.00
18_M	241_A	1.205	1.00
73_T	77_E	1.205	1.00
258_R	261_L	1.201	1.00
396_Y	399_W	1.200	1.00
264_I	267_P	1.199	1.00
178_F	254_G	1.196	1.00
5_L	153_A	1.195	1.00
141_V	297_Y	1.189	1.00
48_A	392_G	1.189	1.00
393_A	403_A	1.185	1.00
92_W	308_P	1.175	1.00
59_I	62_R	1.172	1.00
170_F	174_A	1.170	1.00
398_L	402_Y	1.162	1.00
31_A	39_L	1.161	1.00
389_V	393_A	1.159	1.00
8_S	12_A	1.156	1.00
422_V	426_A	1.154	1.00
411_L	414_V	1.148	1.00
404_S	409_L	1.148	1.00
420_L	424_L	1.148	1.00
131_I	135_S	1.148	1.00
174_A	255_V	1.143	1.00
176_M	181_D	1.141	1.00
397_G	401_L	1.138	1.00
75_A	83_I	1.130	1.00
191_A	194_V	1.129	1.00
273_M	278_G	1.127	1.00
188_T	191_A	1.123	1.00
390_G	396_Y	1.121	1.00
405_G	409_L	1.119	1.00
313_T	322_A	1.119	1.00
144_L	155_I	1.119	1.00
225_R	229_D	1.116	1.00
66_E	73_T	1.115	1.00
175_M	179_K	1.114	1.00
37_A	200_V	1.113	1.00
404_S	407_M	1.112	1.00
417_A	421_L	1.110	1.00
10_L	233_A	1.107	1.00
426_A	429_T	1.107	1.00
132_V	136_A	1.105	1.00
136_A	140_I	1.100	1.00
61_T	74_Y	1.098	1.00
169_L	173_L	1.097	1.00
57_M	71_I	1.096	1.00
414_V	418_P	1.095	1.00
15_L	240_S	1.094	1.00
13_L	220_V	1.093	1.00
415_L	422_V	1.088	1.00
155_I	159_A	1.088	1.00
390_G	400_L	1.082	1.00
422_V	425_Y	1.079	1.00
4_K	225_R	1.074	1.00
324_Q	328_A	1.074	1.00
332_A	335_W	1.062	1.00
394_C	397_G	1.049	1.00
14_V	217_A	1.048	1.00
339_I	343_I	1.043	1.00
142_H	146_L	1.040	1.00
52_L	392_G	1.040	1.00
186_D	189_G	1.037	1.00
44_G	246_L	1.033	1.00
406_P	410_L	1.033	1.00
407_M	410_L	1.029	1.00
196_V	199_Q	1.028	1.00
156_N	298_L	1.028	1.00
107_F	133_G	1.026	1.00
168_G	172_V	1.024	1.00
277_M	281_G	1.017	1.00
371_F	398_L	1.016	1.00
85_F	89_W	1.011	1.00
425_Y	428_K	1.006	1.00
382_T	387_K	1.004	1.00
146_L	329_A	1.003	1.00
394_C	398_L	0.999	1.00
154_S	158_V	0.999	1.00
110_L	290_I	0.989	1.00
212_I	366_I	0.982	1.00
72_F	310_L	0.981	1.00
139_W	143_F	0.977	1.00
278_G	281_G	0.970	1.00
389_V	397_G	0.966	1.00
179_K	182_T	0.966	1.00
190_L	193_G	0.965	1.00
274_V	279_P	0.962	1.00
110_L	114_T	0.961	1.00
186_D	190_L	0.958	1.00
149_V	302_I	0.957	1.00
146_L	325_N	0.956	1.00
66_E	77_E	0.956	1.00
164_L	244_V	0.956	1.00
179_K	183_F	0.952	1.00
389_V	403_A	0.950	1.00
412_S	416_Y	0.948	1.00
388_A	391_V	0.946	1.00
396_Y	400_L	0.938	1.00
140_I	294_C	0.938	1.00
159_A	295_G	0.932	1.00
171_V	251_L	0.926	1.00
407_M	411_L	0.926	1.00
107_F	134_A	0.925	1.00
377_L	381_A	0.918	1.00
364_E	412_S	0.916	1.00
390_G	403_A	0.916	1.00
423_F	426_A	0.914	1.00
197_W	200_V	0.913	1.00
15_L	241_A	0.912	1.00
397_G	403_A	0.908	1.00
101_S	209_W	0.901	1.00
19_L	22_G	0.900	1.00
408_H	411_L	0.899	1.00
176_M	180_L	0.895	1.00
89_W	317_F	0.894	1.00
301_T	338_N	0.890	1.00
393_A	400_L	0.890	1.00
40_L	253_L	0.890	1.00
141_V	298_L	0.889	1.00
4_K	150_Q	0.888	1.00
82_L	86_C	0.886	1.00
221_S	230_V	0.884	1.00
236_L	240_S	0.882	1.00
393_A	402_Y	0.878	1.00
414_V	417_A	0.877	1.00
107_F	130_S	0.875	1.00
412_S	415_L	0.874	1.00
215_E	219_V	0.874	1.00
242_L	246_L	0.873	1.00
101_S	359_L	0.873	1.00
323_R	326_A	0.871	1.00
226_N	231_G	0.869	1.00
69_G	73_T	0.865	1.00
371_F	375_A	0.864	1.00
44_G	48_A	0.860	1.00
250_L	254_G	0.857	1.00
163_K	292_S	0.857	1.00
76_R	314_H	0.856	1.00
279_P	283_I	0.853	1.00
321_F	332_A	0.851	1.00
171_V	175_M	0.848	1.00
190_L	194_V	0.841	1.00
422_V	428_K	0.840	1.00
180_L	183_F	0.840	1.00
133_G	136_A	0.835	1.00
271_G	277_M	0.835	1.00
69_G	72_F	0.834	1.00
12_A	157_L	0.834	1.00
82_L	420_L	0.833	1.00
47_G	211_F	0.830	1.00
36_P	253_L	0.822	1.00
216_G	303_M	0.821	1.00
106_V	294_C	0.818	1.00
338_N	342_Q	0.815	1.00
51_L	55_F	0.811	1.00
9_A	154_S	0.810	1.00
98_A	362_A	0.806	1.00
197_W	201_K	0.806	1.00
60_L	377_L	0.805	1.00
273_M	276_M	0.804	1.00
317_F	321_F	0.803	1.00
202_N	206_I	0.803	1.00
80_G	427_R	0.802	1.00
271_G	278_G	0.801	1.00
423_F	427_R	0.800	1.00
83_I	372_L	0.799	1.00
378_L	391_V	0.799	1.00
75_A	376_F	0.799	1.00
331_S	335_W	0.798	1.00
400_L	403_A	0.797	1.00
410_L	414_V	0.797	1.00
187_F	190_L	0.797	1.00
51_L	235_L	0.792	1.00
79_F	376_F	0.791	1.00
106_V	293_V	0.791	1.00
8_S	157_L	0.790	1.00
393_A	401_L	0.788	1.00
131_I	345_L	0.788	1.00
143_F	146_L	0.787	1.00
376_F	380_I	0.787	1.00
41_I	200_V	0.787	1.00
141_V	301_T	0.785	1.00
273_M	277_M	0.784	1.00
111_S	130_S	0.783	1.00
193_G	200_V	0.783	1.00
175_M	247_L	0.781	1.00
18_M	237_A	0.776	1.00
391_V	401_L	0.772	1.00
396_Y	403_A	0.771	1.00
326_A	331_S	0.771	1.00
52_L	56_A	0.770	1.00
418_P	422_V	0.768	1.00
390_G	401_L	0.766	1.00
410_L	413_V	0.762	1.00
263_E	266_N	0.760	1.00
339_I	342_Q	0.758	1.00
19_L	24_F	0.754	1.00
154_S	157_L	0.753	1.00
257_A	275_E	0.747	1.00
40_L	44_G	0.747	1.00
201_K	399_W	0.747	1.00
231_G	234_T	0.747	1.00
176_M	179_K	0.746	1.00
19_L	163_K	0.745	1.00
23_V	248_V	0.743	1.00
8_S	154_S	0.741	1.00
138_L	345_L	0.740	1.00
188_T	193_G	0.735	1.00
306_E	309_F	0.733	1.00
388_A	396_Y	0.733	1.00
7_L	233_A	0.727	1.00
420_L	423_F	0.727	1.00
59_I	63_I	0.725	1.00
56_A	390_G	0.723	1.00
272_L	275_E	0.722	1.00
193_G	196_V	0.722	1.00
178_F	181_D	0.721	1.00
413_V	416_Y	0.719	1.00
236_L	239_L	0.718	1.00
374_G	394_C	0.716	1.00
415_L	418_P	0.715	1.00
147_R	151_T	0.715	1.00
60_L	74_Y	0.715	1.00
271_G	276_M	0.712	1.00
11_T	233_A	0.710	1.00
418_P	421_L	0.710	1.00
212_I	370_Y	0.707	1.00
72_F	76_R	0.705	1.00
27_P	249_T	0.705	1.00
104_V	358_L	0.703	1.00
247_L	251_L	0.702	1.00
320_I	336_L	0.702	1.00
419_G	426_A	0.702	1.00
135_S	346_V	0.699	1.00
361_I	365_M	0.698	1.00
178_F	182_T	0.697	1.00
391_V	394_C	0.697	1.00
393_A	399_W	0.695	1.00
145_I	302_I	0.694	1.00
409_L	412_S	0.694	1.00
41_I	44_G	0.693	1.00
96_V	340_C	0.693	1.00
145_I	334_L	0.692	1.00
230_V	234_T	0.689	1.00
389_V	396_Y	0.688	1.00
391_V	403_A	0.688	1.00
416_Y	420_L	0.685	1.00
240_S	244_V	0.683	1.00
424_L	427_R	0.683	1.00
308_P	336_L	0.683	1.00
327_Q	331_S	0.683	1.00
41_I	45_I	0.682	1.00
68_D	309_F	0.682	1.00
410_L	415_L	0.677	1.00
178_F	251_L	0.677	1.00
301_T	305_A	0.676	1.00
173_L	278_G	0.675	1.00
222_A	309_F	0.674	1.00
141_V	294_C	0.674	1.00
97_I	361_I	0.670	1.00
11_T	14_V	0.670	1.00
415_L	420_L	0.669	1.00
78_G	379_K	0.668	1.00
419_G	428_K	0.667	1.00
109_A	289_L	0.667	1.00
396_Y	401_L	0.667	1.00
151_T	154_S	0.664	1.00
280_W	283_I	0.663	1.00
411_L	415_L	0.662	1.00
110_L	137_L	0.662	1.00
16_S	160_T	0.662	1.00
98_A	101_S	0.661	1.00
394_C	403_A	0.661	1.00
153_A	157_L	0.658	1.00
354_D	357_T	0.658	1.00
416_Y	419_G	0.656	1.00
218_V	234_T	0.656	1.00
57_M	373_V	0.656	1.00
395_I	398_L	0.656	1.00
4_K	149_V	0.654	1.00
223_R	324_Q	0.650	1.00
59_I	384_P	0.649	1.00
272_L	276_M	0.649	1.00
312_A	321_F	0.648	1.00
139_W	142_H	0.648	1.00
50_I	214_V	0.648	1.00
183_F	254_G	0.648	1.00
127_T	130_S	0.646	1.00
19_L	244_V	0.645	1.00
391_V	399_W	0.645	1.00
184_K	188_T	0.645	1.00
131_I	134_A	0.644	1.00
94_C	366_I	0.644	1.00
72_F	88_A	0.644	1.00
255_V	272_L	0.644	1.00
415_L	423_F	0.643	1.00
171_V	248_V	0.640	1.00
100_V	344_C	0.640	1.00
245_Y	249_T	0.636	1.00
40_L	246_L	0.635	1.00
142_H	301_T	0.633	1.00
91_Y	95_A	0.632	1.00
321_F	333_S	0.631	1.00
389_V	392_G	0.630	1.00
419_G	427_R	0.629	1.00
365_M	369_P	0.628	1.00
78_G	380_I	0.628	1.00
305_A	333_S	0.626	1.00
102_Y	297_Y	0.624	1.00
325_N	328_A	0.623	1.00
248_V	252_S	0.622	1.00
61_T	230_V	0.622	1.00
52_L	389_V	0.622	1.00
392_G	396_Y	0.620	1.00
398_L	401_L	0.620	1.00
149_V	220_V	0.619	1.00
356_N	359_L	0.619	1.00
113_F	287_A	0.617	1.00
390_G	399_W	0.617	1.00
137_L	297_Y	0.617	1.00
39_L	249_T	0.616	1.00
228_R	231_G	0.615	1.00
146_L	334_L	0.614	1.00
173_L	177_M	0.613	1.00
408_H	412_S	0.613	1.00
58_L	62_R	0.612	1.00
406_P	412_S	0.611	1.00
100_V	358_L	0.609	1.00
90_G	369_P	0.608	1.00
36_P	40_L	0.607	1.00
71_I	215_E	0.607	1.00
63_I	380_I	0.606	1.00
34_A	37_A	0.605	1.00
112_F	286_A	0.604	1.00
20_G	245_Y	0.604	1.00
151_T	155_I	0.603	1.00
20_G	24_F	0.602	1.00
391_V	402_Y	0.602	1.00
170_F	273_M	0.602	1.00
422_V	427_R	0.601	1.00
388_A	393_A	0.601	1.00
55_F	389_V	0.601	1.00
70_G	218_V	0.601	1.00
107_F	110_L	0.600	1.00
153_A	298_L	0.597	1.00
414_V	421_L	0.594	1.00
43_W	210_V	0.594	1.00
98_A	102_Y	0.594	1.00
405_G	411_L	0.592	1.00
162_A	288_G	0.591	1.00
61_T	218_V	0.590	1.00
45_I	204_M	0.589	1.00
388_A	399_W	0.588	1.00
388_A	402_Y	0.588	1.00
266_N	271_G	0.587	1.00
199_Q	202_N	0.586	1.00
391_V	397_G	0.584	1.00
54_A	58_L	0.583	1.00
306_E	324_Q	0.580	1.00
304_A	308_P	0.580	1.00
184_K	187_F	0.579	1.00
287_A	291_V	0.579	1.00
54_A	214_V	0.579	1.00
21_A	209_W	0.579	1.00
25_S	28_Q	0.578	1.00
14_V	18_M	0.576	1.00
186_D	192_L	0.575	1.00
13_L	16_S	0.574	1.00
160_T	163_K	0.570	1.00
113_F	286_A	0.570	1.00
26_L	359_L	0.570	1.00
415_L	427_R	0.569	1.00
95_A	300_W	0.569	1.00
240_S	243_G	0.568	1.00
140_I	144_L	0.568	1.00
263_E	267_P	0.566	1.00
219_V	303_M	0.563	1.00
90_G	368_V	0.563	1.00
147_R	327_Q	0.563	1.00
138_L	342_Q	0.562	1.00
184_K	189_G	0.562	1.00
212_I	215_E	0.562	1.00
17_S	300_W	0.562	1.00
224_A	230_V	0.561	1.00
148_G	151_T	0.559	1.00
72_F	84_G	0.558	1.00
405_G	410_L	0.557	1.00
178_F	255_V	0.557	1.00
46_T	211_F	0.557	1.00
408_H	415_L	0.556	1.00
406_P	413_V	0.556	1.00
8_S	11_T	0.555	1.00
223_R	330_P	0.555	1.00
292_S	295_G	0.555	1.00
15_L	160_T	0.553	1.00
162_A	166_P	0.553	1.00
46_T	208_L	0.553	1.00
43_W	249_T	0.553	1.00
366_I	369_P	0.551	1.00
29_N	32_A	0.550	1.00
306_E	330_P	0.549	1.00
251_L	254_G	0.549	1.00
75_A	84_G	0.549	1.00
178_F	183_F	0.547	1.00
413_V	428_K	0.546	1.00
166_P	284_I	0.545	1.00
284_I	288_G	0.544	1.00
152_A	302_I	0.542	1.00
423_F	429_T	0.542	1.00
331_S	334_L	0.541	1.00
421_L	424_L	0.540	1.00
36_P	258_R	0.540	1.00
128_W	133_G	0.540	1.00
417_A	420_L	0.540	1.00
105_I	109_A	0.540	1.00
23_V	167_L	0.539	1.00
100_V	341_V	0.538	1.00
17_S	299_S	0.537	1.00
80_G	84_G	0.535	1.00
137_L	294_C	0.535	1.00
19_L	26_L	0.535	1.00
130_S	134_A	0.535	1.00
136_A	139_W	0.535	1.00
71_I	219_V	0.534	1.00
10_L	220_V	0.533	1.00
212_I	362_A	0.533	1.00
103_L	107_F	0.532	1.00
96_V	337_T	0.531	1.00
355_Y	359_L	0.530	1.00
60_L	78_G	0.530	1.00
4_K	8_S	0.528	1.00
193_G	197_W	0.528	1.00
406_P	415_L	0.527	1.00
183_F	253_L	0.526	1.00
96_V	344_C	0.526	1.00
308_P	312_A	0.525	1.00
258_R	262_A	0.525	1.00
330_P	333_S	0.524	1.00
240_S	247_L	0.523	1.00
108_S	130_S	0.523	1.00
418_P	426_A	0.521	1.00
343_I	346_V	0.520	1.00
139_W	335_W	0.520	1.00
353_S	356_N	0.518	1.00
412_S	419_G	0.518	1.00
184_K	191_A	0.518	1.00
29_N	33_V	0.517	1.00
94_C	365_M	0.517	1.00
58_L	234_T	0.516	1.00
224_A	233_A	0.514	1.00
416_Y	422_V	0.513	1.00
97_I	362_A	0.513	1.00
423_F	428_K	0.511	1.00
24_F	167_L	0.510	1.00
30_M	203_T	0.510	1.00
90_G	94_C	0.510	1.00
301_T	334_L	0.509	1.00
420_L	428_K	0.508	1.00
174_A	178_F	0.505	1.00
165_L	168_G	0.503	1.00
413_V	422_V	0.501	1.00
37_A	192_L	0.500	1.00
29_N	356_N	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.9	100	0.29	Contact Map
3giaA	1	0.9152	100	0.346	Contact Map
4djkA	2	0.8826	100	0.393	Contact Map
2jlnA	1	0.8848	99.1	0.842	Contact Map
3dh4A	3	0.9261	99	0.85	Contact Map
2xq2A	2	0.9239	98.9	0.853	Contact Map
4wgvA	2	0.7913	97.7	0.897	Contact Map
4xp4A	1	0.9326	96.8	0.911	Contact Map
2a65A	2	0.9022	96.1	0.917	Contact Map
4c7rA	3	0.8739	95	0.924	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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