CYCA - ECOLI - GREMLIN Contacts

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CYCA - D-serine/D-alanine/glycine transporter

UniProt:	P0AAE0	Sequences: MVDQVKVVADDQAPAEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFASDLLGPWAGYFTGWTYWFCWVVTGMADVVAITAYAQFWFPDLSDWVASLAVIVLLLTLNLATVKMFGEMEFWFAMIKIVAIVSLIVVGLVMVAMHFQSPTGVEASFAHLWNDGGWFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKDPEKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSVVPEKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAPKAFAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVIGAFTMITTVSAILFMFVWTIILCSYLVYRKQRPHLHEKSIYKMPLGKLMCWVCMAFFVFVVVLLTLEDDTRQALLVTPLWFIALGLGWLFIGKKRAAELRK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12504
Length:	470 (423)
Sequences:	24842 (16028)
Seq/√Len:	779.3

ECOLI - CYCA YIFK PHEP GABP AROP ANSP PROY MMUP LYSP PUUP PLAP POTE FRLA GADC ADIC YGJI YCAM YJEM YBAT ARCD CADB YJEH
BACSU - AAPA ROCC YDGF YBGF HUTM YBXG ROCE YTNA GABP YVBW YFNA YHDG ASPP YBEC YCGH STET ARCD YECA YDAO GERBB GERAB YNDE GERKB
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97U05 Q97XM0 Q97Z63 Q97X49 Q97WS3 Q97ZB5 Q7LXI7 Q97U33 Q97VA6 Q97VR4 Q97VA8 Q97WD4 Q97Y76 Q97YN3 Q97YX9 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
147_L	352_C	4.467	1.00
334_A	346_K	4.284	1.00
396_V	400_Q	3.378	1.00
388_T	423_M	3.193	1.00
64_G	257_I	3.183	1.00
337_K	346_K	3.069	1.00
243_K	247_R	3.001	1.00
24_T	239_K	2.885	1.00
88_S	328_E	2.722	1.00
238_T	244_S	2.705	1.00
104_G	325_L	2.658	1.00
339_S	345_A	2.619	1.00
240_D	243_K	2.610	1.00
326_A	336_A	2.537	1.00
29_Q	251_S	2.480	1.00
334_A	337_K	2.460	1.00
140_L	356_L	2.449	1.00
179_G	266_V	2.442	1.00
25_N	251_S	2.428	1.00
236_A	327_Q	2.409	1.00
294_A	298_V	2.374	1.00
448_L	451_I	2.286	1.00
76_E	398_R	2.269	1.00
444_L	448_L	2.261	1.00
177_V	181_V	2.214	1.00
148_T	152_A	2.204	1.00
25_N	244_S	2.171	1.00
92_S	100_G	2.164	1.00
237_E	320_R	2.134	1.00
349_T	353_I	2.124	1.00
155_K	159_E	2.104	1.00
323_F	327_Q	2.098	1.00
391_L	422_C	2.097	1.00
28_I	238_T	2.086	1.00
25_N	29_Q	2.084	1.00
147_L	348_L	2.082	1.00
144_V	356_L	2.076	1.00
420_W	424_A	2.045	1.00
151_L	345_A	2.035	1.00
285_E	288_V	2.015	1.00
95_L	396_V	1.974	1.00
166_M	170_V	1.959	1.00
359_V	363_Y	1.958	1.00
24_T	27_H	1.934	1.00
450_F	454_G	1.923	1.00
73_A	391_L	1.922	1.00
247_R	251_S	1.906	1.00
48_T	56_I	1.903	1.00
19_L	338_L	1.902	1.00
335_F	350_F	1.872	1.00
92_S	97_P	1.871	1.00
329_G	333_K	1.864	1.00
108_W	351_S	1.864	1.00
95_L	392_C	1.844	1.00
65_F	69_F	1.841	1.00
285_E	289_L	1.835	1.00
275_S	289_L	1.831	1.00
272_P	275_S	1.827	1.00
454_G	458_L	1.768	1.00
27_H	162_F	1.757	1.00
55_S	214_F	1.739	1.00
144_V	352_C	1.739	1.00
250_N	254_I	1.714	1.00
115_G	355_L	1.700	1.00
417_L	421_V	1.700	1.00
150_N	312_N	1.694	1.00
240_D	244_S	1.689	1.00
96_G	99_A	1.684	1.00
91_A	103_T	1.681	1.00
29_Q	255_R	1.671	1.00
103_T	389_I	1.670	1.00
453_L	456_G	1.668	1.00
140_L	361_M	1.665	1.00
451_I	455_L	1.663	1.00
59_V	217_G	1.649	1.00
32_A	252_I	1.642	1.00
339_S	343_V	1.641	1.00
66_M	425_F	1.641	1.00
119_V	311_A	1.623	1.00
143_I	355_L	1.618	1.00
170_V	174_S	1.607	1.00
151_L	349_T	1.595	1.00
424_A	428_F	1.587	1.00
392_C	423_M	1.559	1.00
95_L	99_A	1.558	1.00
195_A	198_A	1.556	1.00
23_L	27_H	1.553	1.00
279_E	285_E	1.535	1.00
396_V	399_K	1.527	1.00
126_A	138_A	1.512	1.00
346_K	350_F	1.508	1.00
288_V	296_A	1.506	1.00
446_T	450_F	1.488	1.00
322_L	347_G	1.488	1.00
254_I	258_M	1.486	1.00
69_F	421_V	1.481	1.00
171_A	302_V	1.479	1.00
234_T	316_F	1.467	1.00
63_I	221_A	1.456	1.00
452_A	456_G	1.456	1.00
91_A	389_I	1.449	1.00
119_V	143_I	1.442	1.00
134_S	137_V	1.438	1.00
442_A	446_T	1.435	1.00
318_T	351_S	1.426	1.00
240_D	247_R	1.424	1.00
143_I	352_C	1.418	1.00
323_F	338_L	1.418	1.00
19_L	323_F	1.412	1.00
438_D	441_Q	1.411	1.00
392_C	396_V	1.409	1.00
84_Y	236_A	1.377	1.00
71_M	253_P	1.368	1.00
333_K	336_A	1.365	1.00
147_L	349_T	1.362	1.00
448_L	452_A	1.362	1.00
65_F	421_V	1.357	1.00
180_L	266_V	1.350	1.00
122_I	304_L	1.349	1.00
169_I	173_V	1.348	1.00
297_S	301_F	1.341	1.00
27_H	158_G	1.339	1.00
122_I	142_V	1.338	1.00
20_R	342_A	1.328	1.00
442_A	458_L	1.327	1.00
140_L	144_V	1.320	1.00
288_V	293_P	1.315	1.00
43_M	121_A	1.315	1.00
319_S	348_L	1.314	1.00
337_K	345_A	1.314	1.00
415_G	419_C	1.304	1.00
333_K	337_K	1.302	1.00
241_P	246_P	1.299	1.00
71_M	249_I	1.297	1.00
437_D	440_R	1.292	1.00
73_A	419_C	1.292	1.00
244_S	247_R	1.291	1.00
281_S	285_E	1.286	1.00
81_N	93_D	1.282	1.00
176_I	262_F	1.264	1.00
25_N	247_R	1.262	1.00
98_W	457_W	1.260	1.00
23_L	158_G	1.257	1.00
175_L	179_G	1.253	1.00
401_R	404_L	1.251	1.00
361_M	364_V	1.249	1.00
183_V	269_S	1.247	1.00
404_L	408_S	1.245	1.00
70_V	391_L	1.240	1.00
444_L	451_I	1.240	1.00
422_C	426_F	1.239	1.00
449_W	453_L	1.236	1.00
80_S	408_S	1.233	1.00
23_L	28_I	1.231	1.00
57_I	265_I	1.228	1.00
94_L	393_S	1.226	1.00
258_M	262_F	1.226	1.00
428_F	432_L	1.218	1.00
72_R	250_N	1.215	1.00
146_L	311_A	1.214	1.00
322_L	331_A	1.213	1.00
89_D	93_D	1.212	1.00
26_R	30_L	1.210	1.00
118_D	310_S	1.208	1.00
180_L	184_A	1.207	1.00
55_S	207_F	1.191	1.00
36_A	256_I	1.172	1.00
136_W	140_L	1.172	1.00
133_L	137_V	1.171	1.00
273_W	276_V	1.147	1.00
416_K	420_W	1.137	1.00
452_A	458_L	1.135	1.00
452_A	457_W	1.132	1.00
362_L	366_P	1.129	1.00
32_A	231_V	1.129	1.00
28_I	248_A	1.124	1.00
414_L	418_M	1.115	1.00
83_E	89_D	1.111	1.00
239_K	244_S	1.106	1.00
279_E	282_P	1.103	1.00
451_I	454_G	1.103	1.00
346_K	349_T	1.102	1.00
31_I	234_T	1.102	1.00
160_M	164_F	1.102	1.00
402_P	408_S	1.096	1.00
74_M	87_F	1.096	1.00
49_I	56_I	1.095	1.00
414_L	417_L	1.093	1.00
149_L	160_M	1.092	1.00
417_L	420_W	1.089	1.00
193_V	198_A	1.085	1.00
394_Y	419_C	1.082	1.00
193_V	196_S	1.082	1.00
395_L	420_W	1.081	1.00
161_E	312_N	1.079	1.00
159_E	163_W	1.078	1.00
443_L	446_T	1.075	1.00
33_I	255_R	1.075	1.00
108_W	322_L	1.072	1.00
22_N	239_K	1.063	1.00
427_V	431_V	1.059	1.00
101_Y	105_W	1.056	1.00
78_L	90_F	1.053	1.00
137_V	141_A	1.048	1.00
327_Q	336_A	1.048	1.00
405_H	408_S	1.047	1.00
445_V	449_W	1.045	1.00
76_E	79_L	1.043	1.00
141_A	145_L	1.037	1.00
179_G	270_V	1.036	1.00
173_V	177_V	1.034	1.00
454_G	457_W	1.031	1.00
450_F	453_L	1.029	1.00
83_E	93_D	1.029	1.00
33_I	256_I	1.027	1.00
123_T	138_A	1.027	1.00
442_A	455_L	1.026	1.00
154_V	316_F	1.019	1.00
147_L	151_L	1.018	1.00
338_L	342_A	1.015	1.00
215_F	428_F	1.014	1.00
88_S	324_G	1.011	1.00
210_G	213_G	1.011	1.00
151_L	343_V	1.011	1.00
174_S	178_V	1.005	1.00
388_T	427_V	1.000	1.00
445_V	448_L	0.995	1.00
144_V	148_T	0.994	1.00
126_A	304_L	0.994	1.00
69_F	418_M	0.992	1.00
169_I	259_F	0.985	1.00
444_L	452_A	0.983	1.00
93_D	401_R	0.981	1.00
453_L	457_W	0.980	1.00
235_A	245_L	0.979	1.00
444_L	455_L	0.978	1.00
423_M	427_V	0.976	1.00
444_L	449_W	0.975	1.00
206_W	209_K	0.971	1.00
448_L	455_L	0.970	1.00
61_M	261_V	0.967	1.00
448_L	453_L	0.965	1.00
164_F	309_S	0.953	1.00
363_Y	366_P	0.953	1.00
442_A	447_P	0.944	1.00
442_A	449_W	0.942	1.00
80_S	404_L	0.941	1.00
272_P	289_L	0.936	1.00
442_A	445_V	0.934	1.00
359_V	364_V	0.934	1.00
447_P	451_I	0.933	1.00
443_L	447_P	0.932	1.00
151_L	339_S	0.928	1.00
85_K	89_D	0.923	1.00
359_V	362_L	0.921	1.00
226_V	383_F	0.920	1.00
391_L	423_M	0.919	1.00
123_T	139_S	0.910	1.00
181_V	184_A	0.909	1.00
229_E	233_T	0.908	1.00
168_K	306_S	0.903	1.00
145_L	308_A	0.902	1.00
176_I	180_L	0.900	1.00
437_D	441_Q	0.899	1.00
204_G	208_P	0.896	1.00
22_N	155_K	0.895	1.00
426_F	429_V	0.894	1.00
282_P	287_F	0.893	1.00
57_I	268_M	0.890	1.00
257_I	261_V	0.885	1.00
444_L	453_L	0.884	1.00
194_E	197_F	0.883	1.00
91_A	99_A	0.882	1.00
430_V	433_L	0.879	1.00
85_K	88_S	0.877	1.00
64_G	225_F	0.874	1.00
30_L	162_F	0.874	1.00
419_C	423_M	0.873	1.00
395_L	419_C	0.871	1.00
345_A	349_T	0.871	1.00
388_T	392_C	0.869	1.00
117_A	223_F	0.868	1.00
337_K	340_K	0.866	1.00
207_F	214_F	0.865	1.00
139_S	360_V	0.862	1.00
315_V	352_C	0.859	1.00
27_H	159_E	0.855	1.00
442_A	448_L	0.852	1.00
270_V	286_L	0.851	1.00
251_S	255_R	0.850	1.00
415_G	418_M	0.847	1.00
80_S	409_I	0.847	1.00
443_L	453_L	0.846	1.00
37_I	40_G	0.844	1.00
19_L	320_R	0.844	1.00
175_L	287_F	0.841	1.00
399_K	416_K	0.840	1.00
444_L	450_F	0.838	1.00
455_L	458_L	0.837	1.00
79_L	409_I	0.837	1.00
282_P	286_L	0.837	1.00
138_A	141_A	0.836	1.00
428_F	431_V	0.836	1.00
340_K	345_A	0.832	1.00
122_I	307_A	0.832	1.00
293_P	297_S	0.829	1.00
362_L	365_N	0.829	1.00
194_E	198_A	0.826	1.00
126_A	130_F	0.826	1.00
335_F	346_K	0.825	1.00
146_L	315_V	0.825	1.00
179_G	183_V	0.825	1.00
61_M	65_F	0.824	1.00
148_T	151_L	0.824	1.00
291_G	295_A	0.824	1.00
96_G	458_L	0.824	1.00
146_L	312_N	0.823	1.00
19_L	22_N	0.823	1.00
92_S	328_E	0.822	1.00
230_L	317_S	0.822	1.00
176_I	266_V	0.821	1.00
117_A	376_T	0.821	1.00
265_I	269_S	0.820	1.00
107_Y	111_W	0.819	1.00
434_T	437_D	0.819	1.00
105_W	331_A	0.817	1.00
25_N	248_A	0.815	1.00
211_L	214_F	0.814	1.00
26_R	162_F	0.811	1.00
287_F	290_V	0.802	1.00
68_F	72_R	0.801	1.00
91_A	393_S	0.800	1.00
403_H	408_S	0.800	1.00
127_Q	131_P	0.794	1.00
443_L	452_A	0.794	1.00
443_L	450_F	0.794	1.00
68_F	250_N	0.794	1.00
19_L	237_E	0.793	1.00
444_L	456_G	0.790	1.00
216_A	220_I	0.789	1.00
120_V	375_I	0.784	1.00
292_L	295_A	0.783	1.00
393_S	397_Y	0.782	1.00
58_F	214_F	0.780	1.00
112_V	354_C	0.774	1.00
388_T	426_F	0.772	1.00
446_T	452_A	0.771	1.00
159_E	162_F	0.770	1.00
352_C	356_L	0.770	1.00
48_T	52_A	0.770	1.00
378_V	382_L	0.768	1.00
402_P	405_H	0.768	1.00
123_T	135_D	0.765	1.00
122_I	308_A	0.765	1.00
419_C	422_C	0.764	1.00
69_F	73_A	0.762	1.00
331_A	335_F	0.761	1.00
353_I	356_L	0.759	1.00
95_L	98_W	0.756	1.00
183_V	266_V	0.755	1.00
442_A	453_L	0.754	1.00
70_V	426_F	0.753	1.00
29_Q	248_A	0.750	1.00
184_A	194_E	0.748	1.00
431_V	435_L	0.744	1.00
443_L	448_L	0.740	1.00
98_W	102_F	0.740	1.00
152_A	156_M	0.740	1.00
99_A	389_I	0.738	1.00
180_L	262_F	0.736	1.00
448_L	457_W	0.734	1.00
444_L	454_G	0.729	1.00
442_A	456_G	0.729	1.00
176_I	263_A	0.727	1.00
136_W	139_S	0.725	1.00
77_L	394_Y	0.723	1.00
226_V	387_W	0.723	1.00
114_T	379_S	0.719	1.00
105_W	448_L	0.715	1.00
29_Q	32_A	0.714	1.00
37_I	168_K	0.712	1.00
26_R	159_E	0.711	1.00
446_T	449_W	0.711	1.00
77_L	90_F	0.708	1.00
281_S	284_V	0.707	1.00
395_L	399_K	0.706	1.00
193_V	197_F	0.702	1.00
197_F	269_S	0.702	1.00
150_N	348_L	0.701	1.00
202_N	205_G	0.699	1.00
41_L	263_A	0.698	1.00
36_A	252_I	0.697	1.00
204_G	207_F	0.697	1.00
432_L	436_E	0.697	1.00
205_G	208_P	0.695	1.00
394_Y	398_R	0.692	1.00
246_P	249_I	0.690	1.00
72_R	418_M	0.686	1.00
320_R	323_F	0.685	1.00
447_P	453_L	0.685	1.00
242_E	409_I	0.683	1.00
449_W	455_L	0.682	1.00
74_M	390_I	0.682	1.00
113_V	378_V	0.681	1.00
240_D	246_P	0.678	1.00
408_S	412_M	0.678	1.00
408_S	411_K	0.677	1.00
67_L	228_I	0.676	1.00
34_G	165_A	0.674	1.00
443_L	457_W	0.674	1.00
322_L	350_F	0.673	1.00
94_L	396_V	0.670	1.00
429_V	433_L	0.666	1.00
22_N	154_V	0.666	1.00
334_A	350_F	0.665	1.00
80_S	402_P	0.664	1.00
443_L	454_G	0.662	1.00
58_F	62_I	0.660	1.00
213_G	216_A	0.659	1.00
116_M	375_I	0.658	1.00
54_P	268_M	0.657	1.00
358_G	365_N	0.657	1.00
123_T	126_A	0.657	1.00
442_A	454_G	0.657	1.00
359_V	365_N	0.656	1.00
315_V	319_S	0.656	1.00
447_P	450_F	0.656	1.00
445_V	450_F	0.656	1.00
255_R	259_F	0.656	1.00
245_L	249_I	0.655	1.00
420_W	423_M	0.655	1.00
158_G	162_F	0.651	1.00
57_I	61_M	0.651	1.00
127_Q	135_D	0.649	1.00
262_F	266_V	0.649	1.00
382_L	386_V	0.649	1.00
150_N	316_F	0.648	1.00
22_N	26_R	0.647	1.00
156_M	159_E	0.646	1.00
236_A	323_F	0.646	1.00
425_F	429_V	0.645	1.00
84_Y	323_F	0.645	1.00
444_L	447_P	0.643	1.00
35_G	314_G	0.642	1.00
106_T	386_V	0.641	1.00
211_L	215_F	0.639	1.00
45_S	264_L	0.639	1.00
429_V	432_L	0.639	1.00
35_G	313_S	0.638	1.00
128_F	300_N	0.637	1.00
335_F	347_G	0.637	1.00
451_I	457_W	0.636	1.00
110_C	383_F	0.636	1.00
339_S	342_A	0.634	1.00
151_L	348_L	0.633	1.00
306_S	309_S	0.633	1.00
114_T	117_A	0.631	1.00
125_Y	303_V	0.631	1.00
294_A	297_S	0.630	1.00
207_F	210_G	0.630	1.00
282_P	290_V	0.629	1.00
419_C	433_L	0.629	1.00
88_S	92_S	0.627	1.00
449_W	452_A	0.626	1.00
44_G	376_T	0.626	1.00
154_V	234_T	0.625	1.00
144_V	147_L	0.624	1.00
446_T	457_W	0.623	1.00
62_I	218_F	0.623	1.00
439_T	443_L	0.621	1.00
95_L	393_S	0.620	1.00
419_C	426_F	0.619	1.00
341_R	345_A	0.618	1.00
58_F	61_M	0.618	1.00
71_M	228_I	0.617	1.00
447_P	454_G	0.617	1.00
319_S	347_G	0.615	1.00
146_L	308_A	0.615	1.00
449_W	456_G	0.614	1.00
251_S	254_I	0.614	1.00
444_L	457_W	0.613	1.00
360_V	363_Y	0.612	1.00
196_S	269_S	0.610	1.00
37_I	259_F	0.609	1.00
129_W	301_F	0.609	1.00
344_P	347_G	0.608	1.00
111_W	314_G	0.607	1.00
69_F	422_C	0.607	1.00
126_A	142_V	0.607	1.00
87_F	229_E	0.607	1.00
37_I	42_F	0.606	1.00
360_V	364_V	0.605	1.00
128_F	131_P	0.605	1.00
215_F	432_L	0.605	1.00
283_F	287_F	0.603	1.00
451_I	456_G	0.602	1.00
75_G	79_L	0.602	1.00
153_T	156_M	0.601	1.00
132_D	135_D	0.599	1.00
450_F	456_G	0.598	1.00
232_G	249_I	0.597	1.00
47_K	373_T	0.597	1.00
142_V	311_A	0.595	1.00
18_S	21_R	0.595	1.00
78_L	232_G	0.595	1.00
446_T	451_I	0.594	1.00
94_L	397_Y	0.594	1.00
442_A	450_F	0.591	1.00
443_L	456_G	0.590	1.00
178_V	182_M	0.590	1.00
158_G	312_N	0.588	1.00
46_G	49_I	0.588	1.00
412_M	415_G	0.587	1.00
301_F	305_T	0.586	1.00
88_S	104_G	0.586	1.00
73_A	422_C	0.586	1.00
326_A	335_F	0.585	1.00
33_I	165_A	0.585	1.00
450_F	457_W	0.585	1.00
422_C	425_F	0.584	1.00
78_L	245_L	0.581	1.00
318_T	322_L	0.581	1.00
280_K	287_F	0.581	1.00
410_Y	413_P	0.580	1.00
56_I	264_L	0.579	1.00
88_S	100_G	0.578	1.00
373_T	376_T	0.577	1.00
237_E	344_P	0.575	1.00
442_A	451_I	0.575	1.00
278_P	282_P	0.574	1.00
395_L	416_K	0.573	1.00
143_I	356_L	0.573	1.00
119_V	123_T	0.573	1.00
60_Y	224_A	0.572	1.00
263_A	267_I	0.571	1.00
57_I	261_V	0.571	1.00
358_G	363_Y	0.571	1.00
446_T	453_L	0.570	1.00
33_I	36_A	0.570	1.00
32_A	36_A	0.569	1.00
167_I	171_A	0.569	1.00
399_K	402_P	0.569	1.00
443_L	449_W	0.568	1.00
63_I	225_F	0.568	1.00
129_W	300_N	0.567	1.00
442_A	452_A	0.566	1.00
238_T	245_L	0.566	1.00
226_V	229_E	0.566	1.00
183_V	270_V	0.565	1.00
63_I	222_V	0.564	1.00
443_L	458_L	0.564	1.00
77_L	94_L	0.563	1.00
202_N	206_W	0.563	1.00
162_F	166_M	0.562	1.00
35_G	230_L	0.561	1.00
241_P	244_S	0.560	1.00
26_R	29_Q	0.560	1.00
255_R	258_M	0.559	1.00
233_T	317_S	0.559	1.00
118_D	311_A	0.558	1.00
413_P	417_L	0.558	1.00
87_F	233_T	0.558	1.00
198_A	202_N	0.558	1.00
114_T	118_D	0.557	1.00
112_V	351_S	0.557	1.00
156_M	160_M	0.556	1.00
284_V	288_V	0.556	1.00
71_M	75_G	0.554	1.00
118_D	121_A	0.554	1.00
51_L	216_A	0.553	1.00
434_T	438_D	0.552	1.00
243_K	246_P	0.551	1.00
165_A	168_K	0.550	1.00
414_L	419_C	0.549	1.00
96_G	100_G	0.548	1.00
446_T	456_G	0.545	1.00
418_M	422_C	0.544	1.00
452_A	455_L	0.544	1.00
157_F	316_F	0.542	1.00
372_F	376_T	0.542	1.00
19_L	84_Y	0.542	1.00
226_V	379_S	0.542	1.00
431_V	434_T	0.541	1.00
255_R	262_F	0.538	1.00
451_I	458_L	0.536	1.00
449_W	457_W	0.535	1.00
167_I	302_V	0.533	1.00
405_H	409_I	0.533	1.00
271_T	275_S	0.532	1.00
57_I	60_Y	0.531	1.00
121_A	125_Y	0.530	1.00
384_M	426_F	0.529	1.00
118_D	307_A	0.529	1.00
445_V	456_G	0.528	1.00
103_T	386_V	0.528	1.00
345_A	348_L	0.527	1.00
266_V	269_S	0.526	1.00
122_I	126_A	0.526	1.00
207_F	211_L	0.525	1.00
287_F	292_L	0.524	1.00
163_W	166_M	0.524	1.00
86_S	232_G	0.523	1.00
167_I	305_T	0.523	1.00
91_A	100_G	0.521	1.00
152_A	341_R	0.519	1.00
59_V	62_I	0.516	1.00
24_T	155_K	0.516	1.00
147_L	315_V	0.514	1.00
320_R	338_L	0.514	1.00
154_V	158_G	0.514	1.00
388_T	430_V	0.514	1.00
436_E	440_R	0.512	1.00
298_V	302_V	0.512	1.00
47_K	50_S	0.512	1.00
319_S	351_S	0.511	1.00
38_G	260_Y	0.510	1.00
152_A	155_K	0.510	1.00
442_A	457_W	0.507	1.00
41_L	44_G	0.507	1.00
322_L	326_A	0.506	1.00
43_M	46_G	0.506	1.00
196_S	202_N	0.505	1.00
45_S	267_I	0.504	1.00
449_W	458_L	0.504	1.00
106_T	385_F	0.504	1.00
231_V	245_L	0.504	1.00
170_V	173_V	0.502	1.00
106_T	110_C	0.502	1.00
263_A	283_F	0.502	1.00
412_M	418_M	0.501	1.00
320_R	344_P	0.500	1.00
48_T	217_G	0.500	1.00
116_M	355_L	0.500	1.00
398_R	415_G	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.8915	100	0.319	Contact Map
4djkA	2	0.8766	100	0.381	Contact Map
3giaA	1	0.8979	100	0.381	Contact Map
3dh4A	3	0.9021	99.2	0.844	Contact Map
2xq2A	2	0.9064	99.1	0.85	Contact Map
2jlnA	1	0.9021	99.1	0.85	Contact Map
4wgvA	2	0.783	98	0.894	Contact Map
2a65A	2	0.9	97.1	0.911	Contact Map
4xp4A	1	0.9064	96.7	0.915	Contact Map
4us3A	1	0.8213	96.6	0.916	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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