GREMLIN Database
YAEQ - Uncharacterized protein YaeQ
UniProt: P0AA97 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13223
Length: 181 (176)
Sequences: 634 (410)
Seq/√Len: 30.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
21_Q25_A5.3471.00
50_Y105_F4.5271.00
73_N77_G3.7431.00
80_L103_A3.2821.00
52_D71_L3.2461.00
154_A163_L3.0761.00
15_A24_D2.9381.00
50_Y103_A2.9131.00
112_A177_W2.6081.00
8_Y37_Q2.5741.00
165_D168_N2.5551.00
42_L84_L2.4570.99
133_Y177_W2.4340.99
14_V25_A2.2710.99
45_L161_I2.2660.99
8_Y31_R2.2430.99
71_L79_D2.2000.99
160_V171_E2.1700.98
54_R74_D2.1190.98
11_T151_T2.0690.98
14_V21_Q1.9830.97
42_L134_L1.9770.97
92_I104_L1.9510.97
86_L139_L1.9500.97
31_R37_Q1.9410.97
25_A47_W1.9000.96
21_Q51_A1.8610.96
96_C129_L1.7910.95
116_W131_V1.7810.95
147_D165_D1.7790.95
95_A102_V1.7240.94
12_V48_L1.6560.92
42_L139_L1.6530.92
48_L154_A1.6440.92
55_L69_A1.6030.91
109_S133_Y1.5710.90
123_C129_L1.5370.89
105_F132_W1.4840.87
72_R76_L1.4830.87
66_E70_W1.4550.86
106_T112_A1.4530.86
134_L139_L1.4200.85
8_Y40_M1.3800.83
160_V173_N1.3680.83
10_A150_M1.3460.81
86_L112_A1.3440.81
83_E92_I1.3400.81
69_A105_F1.3210.80
138_Q172_V1.3010.79
155_T162_W1.2970.79
10_A44_L1.2890.79
29_L44_L1.2640.77
147_D167_K1.2570.77
58_T91_R1.2560.77
60_G68_E1.2540.77
15_A155_T1.2330.75
17_L155_T1.1970.73
18_D159_G1.1910.73
22_F69_A1.1740.72
83_E91_R1.1600.71
29_L40_M1.1510.70
80_L101_E1.1490.70
135_D138_Q1.1220.68
15_A153_Q1.1210.68
15_A74_D1.1120.67
135_D175_T1.0960.66
20_N101_E1.0870.66
58_T70_W1.0780.65
11_T24_D1.0720.65
119_N123_C1.0650.64
79_D100_A1.0470.63
41_M150_M1.0290.61
41_M152_L1.0200.61
90_R162_W1.0190.61
17_L158_D1.0090.60
101_E130_S1.0040.59
121_S124_V1.0040.59
48_L163_L0.9950.59
92_I129_L0.9910.58
106_T133_Y0.9790.57
49_K161_I0.9720.57
145_F152_L0.9380.54
118_Q171_E0.9350.54
67_P72_R0.9330.54
47_W109_S0.9330.54
63_A119_N0.9330.54
24_D163_L0.9120.52
49_K174_L0.9070.52
58_T67_P0.9060.52
86_L106_T0.9040.51
93_K126_F0.8920.50
112_A134_L0.8880.50
58_T61_L0.8860.50
48_L98_Q0.8850.50
138_Q170_L0.8770.49
23_L47_W0.8760.49
21_Q47_W0.8730.49
59_R158_D0.8720.49
75_H126_F0.8620.48
134_L138_Q0.8600.48
41_M145_F0.8580.48
71_L80_L0.8560.48
83_E132_W0.8550.47
16_D19_R0.8540.47
162_W171_E0.8490.47
157_Q162_W0.8480.47
4_K120_Q0.8480.47
84_L126_F0.8460.47
97_T126_F0.8390.46
58_T62_C0.8380.46
41_M146_A0.8360.46
133_Y175_T0.8360.46
58_T68_E0.8310.46
26_S104_L0.8270.45
76_L83_E0.8240.45
24_D170_L0.8220.45
82_I91_R0.8190.45
152_L169_N0.8160.44
42_L98_Q0.8120.44
4_K17_L0.8060.44
68_E84_L0.8030.43
31_R38_E0.8010.43
39_R115_W0.7980.43
122_K149_T0.7980.43
28_T115_W0.7980.43
31_R146_A0.7890.42
62_C83_E0.7880.42
117_Q120_Q0.7830.42
47_W51_A0.7820.42
96_C123_C0.7800.41
145_F170_L0.7790.41
5_A48_L0.7730.41
99_A128_N0.7720.41
161_I174_L0.7710.41
3_L58_T0.7680.41
108_N111_A0.7680.41
109_S136_D0.7660.40
83_E95_A0.7650.40
46_A55_L0.7590.40
63_A68_E0.7550.40
109_S114_I0.7540.39
14_V23_L0.7490.39
145_F165_D0.7410.38
103_A130_S0.7310.38
84_L91_R0.7290.38
5_A155_T0.7270.37
141_K144_A0.7260.37
58_T122_K0.7260.37
38_E109_S0.7210.37
37_Q146_A0.7120.36
127_A144_A0.7090.36
17_L53_E0.7010.35
153_Q164_S0.6990.35
21_Q109_S0.6960.35
63_A93_K0.6950.35
155_T164_S0.6940.35
151_T166_D0.6930.35
46_A105_F0.6920.35
112_A163_L0.6900.35
4_K153_Q0.6850.34
153_Q162_W0.6840.34
90_R118_Q0.6830.34
104_L131_V0.6780.34
18_D160_V0.6770.34
31_R90_R0.6760.34
7_I66_E0.6730.33
48_L89_E0.6730.33
40_M168_N0.6660.33
58_T117_Q0.6650.33
24_D106_T0.6640.33
18_D158_D0.6600.33
58_T63_A0.6600.33
104_L126_F0.6590.32
58_T84_L0.6580.32
142_V146_A0.6580.32
132_W176_A0.6550.32
13_N93_K0.6440.31
138_Q153_Q0.6430.31
31_R84_L0.6430.31
32_H43_R0.6410.31
33_P85_G0.6380.31
44_L161_I0.6360.31
52_D177_W0.6360.31
24_D152_L0.6330.31
10_A29_L0.6310.30
18_D157_Q0.6300.30
49_K83_E0.6300.30
25_A69_A0.6290.30
50_Y130_S0.6280.30
108_N139_L0.6260.30
62_C104_L0.6220.30
105_F151_T0.6210.30
47_W177_W0.6180.30
19_R66_E0.6150.29
38_E143_S0.6140.29
29_L131_V0.6130.29
64_D68_E0.6100.29
19_R53_E0.6100.29
134_L174_L0.6090.29
19_R78_I0.6080.29
73_N79_D0.6060.29
96_C157_Q0.6040.29
67_P134_L0.5970.28
24_D153_Q0.5960.28
12_V47_W0.5950.28
113_Q177_W0.5930.28
53_E134_L0.5920.28
144_A168_N0.5910.28
162_W169_N0.5910.28
86_L111_A0.5830.27
54_R166_D0.5800.27
145_F168_N0.5800.27
93_K97_T0.5750.27
67_P83_E0.5750.27
50_Y132_W0.5700.26
13_N65_D0.5700.26
27_L145_F0.5700.26
164_S169_N0.5680.26
17_L157_Q0.5650.26
3_L61_L0.5630.26
97_T128_N0.5620.26
2_A6_T0.5600.26
67_P91_R0.5590.26
13_N24_D0.5580.26
50_Y101_E0.5570.26
28_T39_R0.5560.26
115_W131_V0.5560.26
3_L13_N0.5550.26
153_Q172_V0.5520.25
132_W154_A0.5510.25
140_A164_S0.5480.25
56_Q117_Q0.5470.25
27_L40_M0.5430.25
119_N126_F0.5400.25
47_W69_A0.5380.25
16_D28_T0.5340.24
40_M146_A0.5330.24
87_P96_C0.5320.24
9_K115_W0.5310.24
38_E131_V0.5280.24
59_R72_R0.5270.24
24_D125_Q0.5270.24
152_L164_S0.5260.24
89_E157_Q0.5260.24
52_D69_A0.5250.24
113_Q117_Q0.5240.24
74_D98_Q0.5210.24
72_R149_T0.5200.23
140_A156_I0.5180.23
83_E104_L0.5140.23
12_V170_L0.5130.23
31_R94_K0.5090.23
84_L87_P0.5070.23
51_A154_A0.5070.23
61_L148_R0.5060.23
104_L129_L0.5050.23
64_D107_Y0.5050.23
19_R88_D0.5040.23
47_W160_V0.5040.23
31_R154_A0.5040.23
64_D129_L0.5020.22
86_L177_W0.5010.22
34_S57_F0.5000.22
87_P104_L0.5000.22
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3c0uA 2 0.989 100 0.006 Contact Map
2g3wA 2 0.9834 100 0.007 Contact Map
2ot9A 1 0.9834 100 0.028 Contact Map
3gb3A 2 0.3149 31.8 0.956 Contact Map
4naoA 2 0.4586 13.2 0.963 Contact Map
4chbA 1 0.6464 10.3 0.965 Contact Map
2nvuB 1 0.4641 9.4 0.966 Contact Map
3wckA 1 0.2762 8.9 0.966 Contact Map
1ew4A 1 0.2928 7.1 0.967 Contact Map
2h8bB 1 0.1657 7 0.967 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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