DOSC - ECOLI - GREMLIN Contacts

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DOSC - Diguanylate cyclase DosC

UniProt:	P0AA89	Sequences: MEMYFKRMKDEWTGLVEQADPPIRAKAAEIAVAHAHYLSIEFYRIVRIDPHAEEFLSNEQVERQLKSAMERWIINVLSAQVDDVERLIQIQHTVAEVHARIGIPVEIVEMGFRVLKKILYPVIFSSDYSAAEKLQVYHFSINSIDIAMEVMTRAFTFSDSSASKEDENYRIFSLLENAEEEKERQIASILSWEIDIIYKILLDSDLGSSLPLSQADFGLWFNHKGRHYFSGIAEVGHISRLIQDFDGIFNQTMRNTRNLNNRSLRVKFLLQIRNTVSQIITLLRELFEEVSRHEVGMDVLTKLLNRRFLPTIFKREIAHANRTGTPLSVLIIDVDKFKEINDTWGHNTGDEILRKVSQAFYDNVRSSDYVFRYGGDEFIIVLTEASENETLRTAERIRSRVEKTKLKAANGEDIALSLSIGAAMFNGHPDYERLIQIADEALYIAKRRGRNRVELWKASL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13793
Length:	460 (396)
Sequences:	1722 (1624)
Seq/√Len:	81.6

ECOLI - DOSC YEGE YEDQ YDAM GMR YEAJ DOSP YLIF YDEH YEAP YEAI YCDT YFIN ADRA YNEF CSRD
BACSU - YTRP YKOW YHCK

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
336_K	450_R	6.547	1.00
365_R	368_D	6.134	1.00
330_L	394_A	5.444	1.00
330_L	420_I	5.080	1.00
445_A	454_E	4.142	1.00
328_S	424_M	3.857	1.00
293_H	297_M	3.798	1.00
395_E	398_R	3.733	1.00
402_E	451_N	3.545	1.00
401_V	418_L	3.488	1.00
439_D	443_Y	3.025	1.00
346_H	439_D	2.806	1.00
352_I	416_L	2.776	1.00
316_E	319_H	2.750	1.00
422_A	453_V	2.710	1.00
436_Q	440_E	2.626	1.00
342_D	443_Y	2.613	1.00
346_H	443_Y	2.526	1.00
303_L	357_S	2.525	1.00
309_L	371_F	2.501	1.00
309_L	379_I	2.498	1.00
313_F	431_Y	2.444	1.00
334_V	356_V	2.408	1.00
342_D	346_H	2.402	1.00
364_V	370_V	2.373	1.00
347_N	436_Q	2.340	1.00
335_D	419_S	2.292	1.00
322_R	365_R	2.286	1.00
382_L	393_T	2.232	1.00
338_K	342_D	2.216	1.00
328_S	390_T	2.207	1.00
332_I	420_I	2.167	1.00
374_G	443_Y	2.147	1.00
430_D	433_R	2.142	1.00
360_F	370_V	2.138	1.00
334_V	418_L	2.121	1.00
376_D	417_S	2.120	1.00
342_D	439_D	2.098	1.00
340_I	352_I	2.084	1.00
338_K	443_Y	2.071	1.00
331_I	442_L	2.066	1.00
331_I	435_I	2.059	1.00
374_G	439_D	2.042	1.00
304_L	308_F	2.037	1.00
338_K	346_H	2.003	1.00
375_G	439_D	1.996	1.00
365_R	396_R	1.991	1.00
417_S	451_N	1.982	1.00
386_S	389_E	1.981	1.00
445_A	449_G	1.971	1.00
303_L	370_V	1.956	1.00
333_D	338_K	1.944	1.00
375_G	443_Y	1.936	1.00
445_A	452_R	1.930	1.00
334_V	353_L	1.928	1.00
359_A	405_K	1.905	1.00
330_L	382_L	1.892	1.00
312_I	315_R	1.856	1.00
398_R	453_V	1.850	1.00
304_L	369_Y	1.825	1.00
330_L	380_I	1.800	1.00
296_G	308_F	1.791	1.00
312_I	371_F	1.757	1.00
394_A	420_I	1.744	1.00
333_D	346_H	1.740	1.00
390_T	394_A	1.736	1.00
346_H	377_E	1.710	1.00
398_R	451_N	1.706	1.00
342_D	375_G	1.704	1.00
429_P	437_I	1.696	1.00
308_F	312_I	1.695	1.00
379_I	435_I	1.692	1.00
284_R	288_E	1.667	1.00
333_D	443_Y	1.648	1.00
426_N	437_I	1.631	1.00
423_A	434_L	1.621	1.00
301_T	353_L	1.616	1.00
319_H	322_R	1.615	1.00
309_L	435_I	1.603	1.00
377_E	443_Y	1.596	1.00
398_R	402_E	1.594	1.00
390_T	422_A	1.589	1.00
421_G	438_A	1.563	1.00
373_Y	435_I	1.561	1.00
346_H	375_G	1.553	1.00
303_L	360_F	1.543	1.00
448_R	452_R	1.529	0.99
331_I	376_D	1.526	0.99
331_I	379_I	1.526	0.99
355_K	358_Q	1.510	0.99
371_F	379_I	1.506	0.99
308_F	369_Y	1.490	0.99
352_I	376_D	1.480	0.99
357_S	370_V	1.476	0.99
337_F	445_A	1.471	0.99
339_E	376_D	1.465	0.99
357_S	360_F	1.454	0.99
333_D	375_G	1.449	0.99
368_D	396_R	1.434	0.99
393_T	396_R	1.419	0.99
448_R	454_E	1.417	0.99
425_F	434_L	1.409	0.99
341_N	349_G	1.388	0.99
352_I	442_L	1.372	0.99
325_T	384_E	1.370	0.99
376_D	442_L	1.368	0.99
444_I	454_E	1.353	0.99
316_E	383_T	1.347	0.99
335_D	450_R	1.345	0.99
376_D	452_R	1.339	0.99
338_K	439_D	1.338	0.99
373_Y	379_I	1.330	0.99
334_V	417_S	1.330	0.99
428_H	437_I	1.318	0.98
299_V	307_R	1.312	0.98
342_D	377_E	1.282	0.98
276_V	279_I	1.245	0.98
374_G	377_E	1.244	0.98
394_A	422_A	1.236	0.98
359_A	404_T	1.234	0.98
328_S	385_A	1.223	0.97
336_K	442_L	1.220	0.97
288_E	292_R	1.211	0.97
316_E	322_R	1.211	0.97
382_L	390_T	1.210	0.97
337_F	353_L	1.204	0.97
206_L	210_L	1.194	0.97
377_E	439_D	1.194	0.97
271_Q	274_N	1.183	0.97
279_I	282_L	1.172	0.97
172_F	176_E	1.171	0.97
385_A	389_E	1.169	0.97
350_D	439_D	1.166	0.97
346_H	374_G	1.161	0.96
317_I	425_F	1.159	0.96
395_E	399_S	1.159	0.96
292_R	296_G	1.159	0.96
333_D	446_K	1.154	0.96
376_D	451_N	1.152	0.96
398_R	417_S	1.148	0.96
420_I	453_V	1.139	0.96
376_D	453_V	1.139	0.96
333_D	377_E	1.135	0.96
336_K	376_D	1.133	0.96
322_R	367_S	1.133	0.96
348_T	409_A	1.128	0.96
310_P	371_F	1.128	0.96
350_D	375_G	1.126	0.96
176_E	180_E	1.124	0.96
309_L	381_V	1.122	0.96
294_E	307_R	1.112	0.95
333_D	342_D	1.111	0.95
439_D	450_R	1.109	0.95
347_N	435_I	1.104	0.95
306_R	350_D	1.099	0.95
337_F	441_A	1.099	0.95
155_F	158_S	1.086	0.95
348_T	414_I	1.070	0.94
338_K	375_G	1.066	0.94
312_I	369_Y	1.057	0.94
442_L	450_R	1.057	0.94
323_T	384_E	1.052	0.94
333_D	439_D	1.049	0.94
417_S	442_L	1.045	0.94
349_G	375_G	1.041	0.94
351_E	355_K	1.031	0.93
331_I	438_A	1.030	0.93
297_M	303_L	1.029	0.93
443_Y	450_R	1.018	0.93
335_D	442_L	1.017	0.93
183_E	187_A	1.014	0.93
317_I	434_L	1.013	0.93
346_H	419_S	1.012	0.93
394_A	418_L	1.011	0.93
376_D	398_R	1.008	0.92
376_D	443_Y	1.006	0.92
351_E	354_R	1.006	0.92
296_G	304_L	1.004	0.92
341_N	377_E	1.001	0.92
329_V	435_I	0.999	0.92
198_Y	206_L	0.996	0.92
219_L	223_H	0.991	0.92
441_A	445_A	0.990	0.92
335_D	417_S	0.990	0.92
335_D	439_D	0.988	0.92
332_I	360_F	0.987	0.92
284_R	287_F	0.981	0.91
309_L	313_F	0.981	0.91
337_F	376_D	0.975	0.91
316_E	327_L	0.972	0.91
375_G	446_K	0.970	0.91
339_E	343_T	0.965	0.91
434_L	437_I	0.965	0.91
297_M	304_L	0.962	0.91
186_I	190_L	0.960	0.91
342_D	419_S	0.960	0.91
423_A	438_A	0.959	0.90
308_F	371_F	0.956	0.90
426_N	434_L	0.953	0.90
327_L	381_V	0.952	0.90
337_F	352_I	0.946	0.90
344_W	352_I	0.944	0.90
338_K	377_E	0.937	0.89
333_D	376_D	0.937	0.89
377_E	446_K	0.936	0.89
333_D	341_N	0.936	0.89
88_I	93_T	0.934	0.89
313_F	381_V	0.931	0.89
346_H	450_R	0.931	0.89
208_S	268_F	0.930	0.89
242_I	246_D	0.928	0.89
338_K	341_N	0.927	0.89
439_D	446_K	0.925	0.89
297_M	442_L	0.925	0.89
356_V	401_V	0.916	0.88
338_K	374_G	0.914	0.88
59_E	63_R	0.914	0.88
342_D	446_K	0.910	0.88
374_G	419_S	0.905	0.88
294_E	299_V	0.897	0.87
317_I	371_F	0.896	0.87
405_K	409_A	0.893	0.87
308_F	311_T	0.891	0.87
346_H	446_K	0.891	0.87
78_S	82_D	0.886	0.87
341_N	375_G	0.884	0.86
330_L	422_A	0.884	0.86
360_F	397_I	0.884	0.86
449_G	452_R	0.883	0.86
261_N	264_L	0.883	0.86
376_D	450_R	0.882	0.86
275_T	279_I	0.881	0.86
320_A	327_L	0.876	0.86
197_I	210_L	0.875	0.86
419_S	439_D	0.872	0.86
282_L	286_L	0.868	0.85
332_I	380_I	0.866	0.85
204_S	221_F	0.864	0.85
198_Y	275_T	0.864	0.85
154_A	157_F	0.857	0.85
171_I	179_E	0.857	0.85
332_I	418_L	0.857	0.85
338_K	450_R	0.854	0.85
346_H	350_D	0.850	0.84
335_D	451_N	0.849	0.84
219_L	255_N	0.843	0.84
162_A	166_D	0.842	0.84
130_A	134_L	0.839	0.84
100_R	103_I	0.837	0.83
338_K	349_G	0.829	0.83
280_I	285_E	0.827	0.83
213_S	223_H	0.827	0.83
376_D	445_A	0.826	0.83
242_I	248_I	0.825	0.82
87_L	91_Q	0.822	0.82
335_D	449_G	0.820	0.82
376_D	439_D	0.816	0.82
333_D	349_G	0.816	0.82
206_L	213_S	0.815	0.82
419_S	443_Y	0.812	0.81
398_R	418_L	0.811	0.81
279_I	284_R	0.810	0.81
402_E	417_S	0.806	0.81
431_Y	435_I	0.805	0.81
261_N	268_F	0.804	0.81
337_F	442_L	0.802	0.81
385_A	390_T	0.801	0.81
337_F	449_G	0.799	0.80
333_D	374_G	0.794	0.80
444_I	447_R	0.790	0.80
254_R	258_N	0.787	0.79
423_A	437_I	0.781	0.79
350_D	372_R	0.781	0.79
212_L	215_A	0.779	0.79
72_W	76_V	0.778	0.79
299_V	373_Y	0.777	0.79
87_L	94_V	0.773	0.78
300_L	377_E	0.772	0.78
308_F	442_L	0.772	0.78
355_K	359_A	0.772	0.78
340_I	405_K	0.771	0.78
88_I	94_V	0.770	0.78
409_A	412_E	0.769	0.78
263_S	269_L	0.768	0.78
342_D	374_G	0.767	0.78
168_N	175_L	0.767	0.78
376_D	449_G	0.766	0.78
237_H	240_R	0.766	0.78
374_G	446_K	0.764	0.77
210_L	279_I	0.763	0.77
242_I	245_F	0.762	0.77
93_T	96_E	0.762	0.77
289_E	292_R	0.760	0.77
365_R	393_T	0.760	0.77
340_I	415_A	0.759	0.77
63_R	68_A	0.758	0.77
417_S	449_G	0.758	0.77
342_D	450_R	0.756	0.77
365_R	385_A	0.755	0.77
398_R	401_V	0.754	0.76
308_F	416_L	0.747	0.76
287_F	291_S	0.746	0.76
331_I	373_Y	0.744	0.75
344_W	376_D	0.744	0.75
306_R	374_G	0.744	0.75
297_M	376_D	0.743	0.75
342_D	350_D	0.742	0.75
254_R	257_R	0.740	0.75
427_G	455_L	0.738	0.75
352_I	409_A	0.738	0.75
341_N	346_H	0.736	0.75
352_I	371_F	0.730	0.74
299_V	310_P	0.728	0.74
327_L	425_F	0.728	0.74
168_N	172_F	0.728	0.74
290_V	294_E	0.727	0.74
443_Y	446_K	0.727	0.74
73_I	80_Q	0.726	0.74
295_V	308_F	0.725	0.74
322_R	368_D	0.725	0.74
368_D	393_T	0.725	0.74
285_E	288_E	0.723	0.73
296_G	307_R	0.722	0.73
421_G	443_Y	0.722	0.73
176_E	186_I	0.721	0.73
344_W	414_I	0.721	0.73
444_I	448_R	0.721	0.73
311_T	315_R	0.719	0.73
186_I	193_E	0.715	0.73
119_L	123_I	0.709	0.72
328_S	422_A	0.708	0.72
162_A	165_E	0.706	0.72
304_L	331_I	0.703	0.71
352_I	406_L	0.703	0.71
306_R	346_H	0.702	0.71
70_E	73_I	0.696	0.71
349_G	377_E	0.695	0.70
385_A	424_M	0.693	0.70
356_V	416_L	0.692	0.70
146_I	151_M	0.690	0.70
95_A	102_G	0.685	0.69
154_A	159_D	0.684	0.69
68_A	76_V	0.683	0.69
338_K	446_K	0.683	0.69
340_I	343_T	0.683	0.69
364_V	393_T	0.682	0.69
182_K	185_Q	0.682	0.69
67_S	74_I	0.681	0.69
62_E	75_N	0.679	0.69
199_K	210_L	0.679	0.69
180_E	183_E	0.678	0.69
307_R	352_I	0.678	0.69
277_S	280_I	0.676	0.68
371_F	431_Y	0.674	0.68
423_A	441_A	0.673	0.68
300_L	349_G	0.669	0.67
109_E	113_R	0.668	0.67
98_H	103_I	0.668	0.67
337_F	419_S	0.668	0.67
295_V	342_D	0.667	0.67
349_G	446_K	0.666	0.67
300_L	333_D	0.664	0.67
307_R	365_R	0.664	0.67
276_V	280_I	0.664	0.67
121_P	126_S	0.663	0.67
189_I	194_I	0.662	0.67
62_E	65_L	0.662	0.67
226_R	242_I	0.661	0.67
295_V	373_Y	0.661	0.67
266_V	273_R	0.660	0.66
196_I	216_D	0.656	0.66
333_D	372_R	0.656	0.66
333_D	350_D	0.655	0.66
156_T	162_A	0.655	0.66
74_I	78_S	0.653	0.66
215_A	223_H	0.653	0.66
372_R	419_S	0.652	0.66
346_H	349_G	0.652	0.66
399_S	402_E	0.651	0.65
191_S	196_I	0.650	0.65
59_E	78_S	0.647	0.65
365_R	382_L	0.646	0.65
387_E	455_L	0.645	0.65
275_T	280_I	0.645	0.65
311_T	369_Y	0.643	0.64
238_I	241_L	0.641	0.64
360_F	364_V	0.640	0.64
60_Q	65_L	0.639	0.64
296_G	312_I	0.639	0.64
336_K	340_I	0.639	0.64
58_N	63_R	0.638	0.64
179_E	183_E	0.638	0.64
342_D	349_G	0.638	0.64
206_L	211_P	0.637	0.64
124_F	130_A	0.637	0.64
61_V	64_Q	0.635	0.63
60_Q	63_R	0.634	0.63
302_K	354_R	0.633	0.63
338_K	376_D	0.633	0.63
356_V	418_L	0.632	0.63
185_Q	203_D	0.630	0.63
157_F	161_S	0.629	0.63
244_D	248_I	0.628	0.63
317_I	320_A	0.628	0.63
370_V	380_I	0.626	0.62
72_W	78_S	0.625	0.62
342_D	376_D	0.625	0.62
78_S	84_V	0.624	0.62
291_S	294_E	0.624	0.62
343_T	397_I	0.624	0.62
359_A	363_N	0.623	0.62
126_S	140_S	0.623	0.62
196_I	199_K	0.623	0.62
61_V	68_A	0.623	0.62
91_Q	95_A	0.622	0.62
138_H	142_N	0.621	0.62
407_K	413_D	0.621	0.62
63_R	66_K	0.621	0.62
59_E	68_A	0.619	0.62
395_E	453_V	0.617	0.61
75_N	79_A	0.617	0.61
114_V	117_K	0.616	0.61
66_K	81_V	0.616	0.61
191_S	216_D	0.616	0.61
417_S	450_R	0.615	0.61
279_I	285_E	0.614	0.61
254_R	271_Q	0.613	0.61
352_I	398_R	0.613	0.61
306_R	310_P	0.611	0.61
189_I	200_I	0.608	0.60
99_A	105_V	0.607	0.60
383_T	390_T	0.607	0.60
300_L	341_N	0.606	0.60
186_I	197_I	0.606	0.60
346_H	376_D	0.605	0.60
91_Q	104_P	0.605	0.60
304_L	379_I	0.604	0.60
336_K	339_E	0.604	0.60
334_V	442_L	0.603	0.60
296_G	371_F	0.603	0.60
68_A	74_I	0.603	0.60
70_E	78_S	0.602	0.59
409_A	414_I	0.601	0.59
86_R	90_I	0.601	0.59
195_D	278_Q	0.601	0.59
328_S	394_A	0.600	0.59
110_M	116_K	0.598	0.59
74_I	80_Q	0.598	0.59
169_Y	172_F	0.597	0.59
130_A	133_K	0.595	0.58
425_F	428_H	0.593	0.58
135_Q	144_I	0.593	0.58
241_L	245_F	0.593	0.58
340_I	414_I	0.592	0.58
391_L	453_V	0.591	0.58
391_L	395_E	0.591	0.58
295_V	439_D	0.591	0.58
239_S	242_I	0.590	0.58
320_A	425_F	0.590	0.58
61_V	70_E	0.589	0.58
364_V	368_D	0.588	0.58
183_E	189_I	0.588	0.58
310_P	432_E	0.588	0.58
107_I	112_F	0.586	0.57
147_A	160_S	0.586	0.57
295_V	436_Q	0.584	0.57
423_A	426_N	0.584	0.57
335_D	346_H	0.583	0.57
104_P	108_V	0.583	0.57
205_D	210_L	0.582	0.57
346_H	442_L	0.581	0.57
319_H	383_T	0.580	0.57
339_E	417_S	0.576	0.56
174_L	177_N	0.576	0.56
360_F	451_N	0.576	0.56
240_R	253_M	0.575	0.56
320_A	324_G	0.572	0.56
332_I	435_I	0.572	0.56
91_Q	98_H	0.572	0.56
234_E	241_L	0.571	0.55
263_S	278_Q	0.571	0.55
96_E	103_I	0.570	0.55
345_G	349_G	0.569	0.55
133_K	136_V	0.569	0.55
196_I	200_I	0.568	0.55
147_A	155_F	0.568	0.55
161_S	168_N	0.568	0.55
199_K	202_L	0.568	0.55
212_L	219_L	0.568	0.55
387_E	424_M	0.566	0.55
330_L	393_T	0.565	0.55
406_L	416_L	0.564	0.54
297_M	340_I	0.562	0.54
359_A	398_R	0.562	0.54
68_A	73_I	0.561	0.54
402_E	415_A	0.560	0.54
88_I	103_I	0.559	0.54
278_Q	282_L	0.559	0.54
115_L	120_Y	0.559	0.54
161_S	164_K	0.558	0.54
352_I	369_Y	0.558	0.54
306_R	439_D	0.557	0.54
306_R	345_G	0.557	0.54
398_R	450_R	0.557	0.54
190_L	193_E	0.555	0.53
337_F	394_A	0.555	0.53
307_R	376_D	0.552	0.53
334_V	398_R	0.552	0.53
70_E	75_N	0.552	0.53
304_L	371_F	0.551	0.53
323_T	367_S	0.551	0.53
387_E	390_T	0.550	0.53
77_L	81_V	0.549	0.53
179_E	185_Q	0.549	0.53
392_R	396_R	0.548	0.52
295_V	419_S	0.547	0.52
87_L	98_H	0.544	0.52
305_N	378_F	0.544	0.52
72_W	79_A	0.543	0.52
348_T	351_E	0.543	0.52
67_S	70_E	0.543	0.52
344_W	442_L	0.542	0.52
389_E	392_R	0.542	0.52
59_E	79_A	0.540	0.51
177_N	181_E	0.540	0.51
300_L	353_L	0.540	0.51
60_Q	77_L	0.540	0.51
277_S	281_T	0.539	0.51
84_V	87_L	0.538	0.51
372_R	375_G	0.538	0.51
312_I	316_E	0.538	0.51
175_L	183_E	0.537	0.51
380_I	422_A	0.536	0.51
257_R	260_N	0.536	0.51
73_I	78_S	0.535	0.51
69_M	72_W	0.534	0.51
364_V	397_I	0.534	0.51
94_V	103_I	0.533	0.50
145_D	159_D	0.532	0.50
160_S	165_E	0.531	0.50
226_R	249_F	0.531	0.50
58_N	62_E	0.531	0.50
150_V	154_A	0.531	0.50
258_N	265_R	0.530	0.50
317_I	431_Y	0.529	0.50
185_Q	199_K	0.529	0.50
170_R	175_L	0.528	0.50
151_M	154_A	0.527	0.50
223_H	231_G	0.525	0.49
158_S	161_S	0.525	0.49
312_I	381_V	0.525	0.49
74_I	77_L	0.524	0.49
303_L	352_I	0.524	0.49
62_E	68_A	0.523	0.49
358_Q	361_Y	0.523	0.49
67_S	73_I	0.522	0.49
285_E	289_E	0.522	0.49
345_G	406_L	0.521	0.49
226_R	229_F	0.521	0.49
407_K	411_G	0.521	0.49
62_E	80_Q	0.520	0.49
414_I	442_L	0.518	0.48
229_F	232_I	0.517	0.48
71_R	74_I	0.517	0.48
334_V	436_Q	0.517	0.48
223_H	229_F	0.516	0.48
296_G	431_Y	0.515	0.48
237_H	244_D	0.513	0.48
365_R	443_Y	0.512	0.48
440_E	447_R	0.512	0.48
297_M	331_I	0.512	0.48
327_L	384_E	0.512	0.48
280_I	288_E	0.511	0.48
162_A	172_F	0.511	0.48
76_V	80_Q	0.508	0.47
58_N	77_L	0.508	0.47
150_V	209_S	0.508	0.47
259_L	264_L	0.508	0.47
220_W	225_G	0.507	0.47
446_K	450_R	0.507	0.47
369_Y	381_V	0.506	0.47
300_L	372_R	0.506	0.47
308_F	316_E	0.506	0.47
120_Y	127_D	0.506	0.47
119_L	126_S	0.505	0.47
136_V	139_F	0.505	0.47
238_I	242_I	0.504	0.47
146_I	169_Y	0.503	0.47
382_L	441_A	0.502	0.46
196_I	334_V	0.502	0.46
254_R	260_N	0.502	0.46
179_E	184_R	0.501	0.46
183_E	186_I	0.501	0.46
61_V	71_R	0.500	0.46

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1w25A	2	0.6457	100	0.473	Contact Map
4h54A	2	0.5891	100	0.495	Contact Map
4j40A	2	0	100	0.499	Contact Map
3pjxA	1	0.3848	100	0.507	Contact Map
3ezuA	2	0.663	100	0.511	Contact Map
4rnhA	2	0.3457	100	0.517	Contact Map
3i5cA	2	0.4196	100	0.522	Contact Map
3tvkA	1	0.3609	100	0.529	Contact Map
3ignA	1	0.3587	100	0.531	Contact Map
3mtkA	2	0.3457	100	0.532	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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